HTRA1 (high temperature requirement a serine peptidase 1) gene is transcriptionally regulated by insertion/deletion nucleotides located at the 3′ end of the ARMS2 (age-related maculopathy susceptibility 2) gene in patients with age-related macular degeneration

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 2784-2797

  Iejima, Daisuke ^a   Itabashi, Takeshi ^a   Kawamura, Yuich ^a   Noda, Toru ^b   Yuasa, Shinsuke ^c   Fukuda, Keiichi ^c   Oka, Chio ^d   Iwata, Takeshi ^a  

^a National Institute of Sensory Organs   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION TOKYO MEDICAL CENTER   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELLS; CYTOLOGY; GENES; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; OPHTHALMOLOGY; PROTEINS; STEM CELLS; VISION;

AGE-RELATED MACULAR DEGENERATION; DOUBLE STRANDED DNA; GENOME-WIDE ASSOCIATION STUDIES; HIGH TEMPERATURE; INDUCED PLURIPOTENT STEM CELLS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; PHOTORECEPTOR CELL; REGULATORY REGIONS;

TRANSCRIPTION;

BETA GALACTOSIDASE; COMPLEMENTARY DNA; DOUBLE STRANDED DNA; LYRIC PROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; ARMS2 PROTEIN, HUMAN; HTRA1 PROTEIN, HUMAN; PROTEIN; SERINE PROTEINASE;

3' UNTRANSLATED REGION; ADULT; AGE RELATED MACULAR DEGENERATION; AGED; ANIMAL CELL; ARMS2 GENE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA PROBE; EXON; FEMALE; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE INSERTION; GENE LOCATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HETEROZYGOSITY; HTRA1 GENE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PLURIPOTENT STEM CELL; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; CELL LINE; GEL MOBILITY SHIFT ASSAY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; METABOLISM; MUTATION; RAT; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

MUS; MUS MUSCULUS;

AGED; ANIMALS; BLOTTING, WESTERN; CELL LINE; CHROMATOGRAPHY, LIQUID; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, KNOCKOUT; MUTATION; PROTEINS; RATS; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE ENDOPEPTIDASES; TANDEM MASS SPECTROMETRY;

EID: 84921917037     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.593384     Document Type: Article

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