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Volumn 23, Issue , 2014, Pages 47-55

Targeting B-cell lymphomas with inhibitors of the MALT1 paracaspase

Author keywords

[No Author keywords available]

Indexed keywords

5 [4 (2 DIETHYLAMINOETHYLAMINO) 3 NITROPHENYL] 1,4 DIPHENYL 1,2,4 TRIAZOLIUM 3 THIOLATE; ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MOLECULAR SCAFFOLD; MUCOSA ASSOCIATED LYMPHOID TISSUE PROTEIN 1; MUCOSA ASSOCIATED LYMPHOID TISSUE PROTEIN 1 INHIBITOR; PECAZINE; PROTEINASE; PROTEINASE INHIBITOR; THIORIDAZINE; UNCLASSIFIED DRUG; CASPASE; ENZYME INHIBITOR; MALT1 PROTEIN, HUMAN; TUMOR PROTEIN;

EID: 84921898265     PISSN: 13675931     EISSN: 18790402     Source Type: Journal    
DOI: 10.1016/j.cbpa.2014.09.025     Document Type: Review
Times cited : (15)

References (60)
  • 1
    • 79955835059 scopus 로고    scopus 로고
    • Pathogenesis of non-Hodgkin's lymphoma
    • Nogai H., Dorken B., Lenz G. Pathogenesis of non-Hodgkin's lymphoma. J Clin Oncol 2011, 29:1803-1811.
    • (2011) J Clin Oncol , vol.29 , pp. 1803-1811
    • Nogai, H.1    Dorken, B.2    Lenz, G.3
  • 2
    • 84867168141 scopus 로고    scopus 로고
    • Lymphoid malignancies: many tumor types, many altered genes, many therapeutic challenges
    • Dalla-Favera R. Lymphoid malignancies: many tumor types, many altered genes, many therapeutic challenges. J Clin Invest 2012, 122:3396-3397.
    • (2012) J Clin Invest , vol.122 , pp. 3396-3397
    • Dalla-Favera, R.1
  • 3
    • 3543066288 scopus 로고    scopus 로고
    • MALT lymphoma: from morphology to molecules
    • Isaacson P.G., Du M.Q. MALT lymphoma: from morphology to molecules. Nat Rev Cancer 2004, 4:644-653.
    • (2004) Nat Rev Cancer , vol.4 , pp. 644-653
    • Isaacson, P.G.1    Du, M.Q.2
  • 4
    • 0033638182 scopus 로고    scopus 로고
    • Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
    • Uren A.G., O'Rourke K., Aravind L.A., Pisabarro M.T., Seshagiri S., Koonin E.V., Dixit V.M. Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell 2000, 6:961-967.
    • (2000) Mol Cell , vol.6 , pp. 961-967
    • Uren, A.G.1    O'Rourke, K.2    Aravind, L.A.3    Pisabarro, M.T.4    Seshagiri, S.5    Koonin, E.V.6    Dixit, V.M.7
  • 5
    • 0035374349 scopus 로고    scopus 로고
    • Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway
    • Lucas P.C., Yonezumi M., Inohara N., McAllister-Lucas L.M., Abazeed M.E., Chen F.F., Yamaoka S., Seto M., Nunez G. Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem 2001, 276:19012-19019.
    • (2001) J Biol Chem , vol.276 , pp. 19012-19019
    • Lucas, P.C.1    Yonezumi, M.2    Inohara, N.3    McAllister-Lucas, L.M.4    Abazeed, M.E.5    Chen, F.F.6    Yamaoka, S.7    Seto, M.8    Nunez, G.9
  • 6
    • 19344373133 scopus 로고    scopus 로고
    • Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity
    • Zhou H., Du M.Q., Dixit V.M. Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity. Cancer Cell 2005, 7:425-431.
    • (2005) Cancer Cell , vol.7 , pp. 425-431
    • Zhou, H.1    Du, M.Q.2    Dixit, V.M.3
  • 8
    • 1942469524 scopus 로고    scopus 로고
    • MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation
    • Che T., You Y., Wang D., Tanner M.J., Dixit V.M., Lin X. MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation. J Biol Chem 2004, 279:15870-15876.
    • (2004) J Biol Chem , vol.279 , pp. 15870-15876
    • Che, T.1    You, Y.2    Wang, D.3    Tanner, M.J.4    Dixit, V.M.5    Lin, X.6
  • 9
    • 37549011707 scopus 로고    scopus 로고
    • IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells
    • Shinohara H., Maeda S., Watarai H., Kurosaki T. IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells. J Exp Med 2007, 204:3285-3293.
    • (2007) J Exp Med , vol.204 , pp. 3285-3293
    • Shinohara, H.1    Maeda, S.2    Watarai, H.3    Kurosaki, T.4
  • 10
    • 2342629277 scopus 로고    scopus 로고
    • The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
    • Sun L., Deng L., Ea C.K., Xia Z.P., Chen Z.J. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 2004, 14:289-301.
    • (2004) Mol Cell , vol.14 , pp. 289-301
    • Sun, L.1    Deng, L.2    Ea, C.K.3    Xia, Z.P.4    Chen, Z.J.5
  • 11
    • 34249863050 scopus 로고    scopus 로고
    • A novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2-MALT1 fusions
    • Noels H., van Loo G., Hagens S., Broeckx V., Beyaert R., Marynen P., Baens M. A novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2-MALT1 fusions. J Biol Chem 2007, 282:10180-10189.
    • (2007) J Biol Chem , vol.282 , pp. 10180-10189
    • Noels, H.1    van Loo, G.2    Hagens, S.3    Broeckx, V.4    Beyaert, R.5    Marynen, P.6    Baens, M.7
  • 18
    • 84900440370 scopus 로고    scopus 로고
    • Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation
    • Nakaya M., Xiao Y., Zhou X., Chang J.H., Chang M., Cheng X., Blonska M., Lin X., Sun S.C. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity 2014, 40:692-705.
    • (2014) Immunity , vol.40 , pp. 692-705
    • Nakaya, M.1    Xiao, Y.2    Zhou, X.3    Chang, J.H.4    Chang, M.5    Cheng, X.6    Blonska, M.7    Lin, X.8    Sun, S.C.9
  • 20
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • Karin M., Cao Y., Greten F.R., Li Z.W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002, 2:301-310.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 22
    • 84899101931 scopus 로고    scopus 로고
    • A catalytic-independent role for the LUBAC in NF-kappaB activation upon antigen receptor engagement and in lymphoma cells
    • Dubois S.M., Alexia C., Wu Y., Leclair H.M., Leveau C., Schol E., Fest T., Tarte K., Chen Z.J., Gavard J., et al. A catalytic-independent role for the LUBAC in NF-kappaB activation upon antigen receptor engagement and in lymphoma cells. Blood 2014, 123:2199-2203.
    • (2014) Blood , vol.123 , pp. 2199-2203
    • Dubois, S.M.1    Alexia, C.2    Wu, Y.3    Leclair, H.M.4    Leveau, C.5    Schol, E.6    Fest, T.7    Tarte, K.8    Chen, Z.J.9    Gavard, J.10
  • 28
    • 70449713757 scopus 로고    scopus 로고
    • Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells
    • Ferch U., Kloo B., Gewies A., Pfander V., Duwel M., Peschel C., Krappmann D., Ruland J. Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells. J Exp Med 2009, 206:2313-2320.
    • (2009) J Exp Med , vol.206 , pp. 2313-2320
    • Ferch, U.1    Kloo, B.2    Gewies, A.3    Pfander, V.4    Duwel, M.5    Peschel, C.6    Krappmann, D.7    Ruland, J.8
  • 31
    • 84875185728 scopus 로고    scopus 로고
    • Targeting pathological B cell receptor signalling in lymphoid malignancies
    • Young R.M., Staudt L.M. Targeting pathological B cell receptor signalling in lymphoid malignancies. Nat Rev Drug Discov 2013, 12:229-243.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 229-243
    • Young, R.M.1    Staudt, L.M.2
  • 34
    • 33750344655 scopus 로고    scopus 로고
    • The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes
    • Rawlings D.J., Sommer K., Moreno-Garcia M.E. The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes. Nat Rev Immunol 2006, 6:799-812.
    • (2006) Nat Rev Immunol , vol.6 , pp. 799-812
    • Rawlings, D.J.1    Sommer, K.2    Moreno-Garcia, M.E.3
  • 37
    • 0033554647 scopus 로고    scopus 로고
    • A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue
    • Akagi T., Motegi M., Tamura A., Suzuki R., Hosokawa Y., Suzuki H., Ota H., Nakamura S., Morishima Y., Taniwaki M., et al. A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. Oncogene 1999, 18:5785-5794.
    • (1999) Oncogene , vol.18 , pp. 5785-5794
    • Akagi, T.1    Motegi, M.2    Tamura, A.3    Suzuki, R.4    Hosokawa, Y.5    Suzuki, H.6    Ota, H.7    Nakamura, S.8    Morishima, Y.9    Taniwaki, M.10
  • 38
    • 0033572308 scopus 로고    scopus 로고
    • Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18
    • Morgan J.A., Yin Y., Borowsky A.D., Kuo F., Nourmand N., Koontz J.I., Reynolds C., Soreng L., Griffin C.A., Graeme-Cook F., et al. Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18. Cancer Res 1999, 59:6205-6213.
    • (1999) Cancer Res , vol.59 , pp. 6205-6213
    • Morgan, J.A.1    Yin, Y.2    Borowsky, A.D.3    Kuo, F.4    Nourmand, N.5    Koontz, J.I.6    Reynolds, C.7    Soreng, L.8    Griffin, C.A.9    Graeme-Cook, F.10
  • 40
    • 0033847542 scopus 로고    scopus 로고
    • The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation
    • Baens M., Maes B., Steyls A., Geboes K., Marynen P., De Wolf-Peeters C. The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation. Am J Pathol 2000, 156:1433-1439.
    • (2000) Am J Pathol , vol.156 , pp. 1433-1439
    • Baens, M.1    Maes, B.2    Steyls, A.3    Geboes, K.4    Marynen, P.5    De Wolf-Peeters, C.6
  • 42
    • 0037443498 scopus 로고    scopus 로고
    • T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma
    • Streubel B., Lamprecht A., Dierlamm J., Cerroni L., Stolte M., Ott G., Raderer M., Chott A. T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 2003, 101:2335-2339.
    • (2003) Blood , vol.101 , pp. 2335-2339
    • Streubel, B.1    Lamprecht, A.2    Dierlamm, J.3    Cerroni, L.4    Stolte, M.5    Ott, G.6    Raderer, M.7    Chott, A.8
  • 44
    • 13844266269 scopus 로고    scopus 로고
    • MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression
    • Ye H., Gong L., Liu H., Hamoudi R.A., Shirali S., Ho L., Chott A., Streubel B., Siebert R., Gesk S., et al. MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol 2005, 205:293-301.
    • (2005) J Pathol , vol.205 , pp. 293-301
    • Ye, H.1    Gong, L.2    Liu, H.3    Hamoudi, R.A.4    Shirali, S.5    Ho, L.6    Chott, A.7    Streubel, B.8    Siebert, R.9    Gesk, S.10
  • 46
    • 0032958801 scopus 로고    scopus 로고
    • Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)
    • Zhang Q., Siebert R., Yan M., Hinzmann B., Cui X., Xue L., Rakestraw K.M., Naeve C.W., Beckmann G., Weisenburger D.D., et al. Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet 1999, 22:63-68.
    • (1999) Nat Genet , vol.22 , pp. 63-68
    • Zhang, Q.1    Siebert, R.2    Yan, M.3    Hinzmann, B.4    Cui, X.5    Xue, L.6    Rakestraw, K.M.7    Naeve, C.W.8    Beckmann, G.9    Weisenburger, D.D.10
  • 47
    • 84958778236 scopus 로고    scopus 로고
    • Detection and measurement of paracaspase MALT1 activity
    • Hailfinger S., Pelzer C., Thome M. Detection and measurement of paracaspase MALT1 activity. Methods Mol Biol 2014, 1133:177-188.
    • (2014) Methods Mol Biol , vol.1133 , pp. 177-188
    • Hailfinger, S.1    Pelzer, C.2    Thome, M.3
  • 50
    • 84862907834 scopus 로고    scopus 로고
    • Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region
    • Yu J.W., Jeffrey P.D., Ha J.Y., Yang X., Shi Y. Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region. Proc Natl Acad Sci U S A 2011, 108:21004-21009.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 21004-21009
    • Yu, J.W.1    Jeffrey, P.D.2    Ha, J.Y.3    Yang, X.4    Shi, Y.5
  • 52
    • 84897925144 scopus 로고    scopus 로고
    • Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface
    • Cabalzar K., Pelzer C., Wolf A., Lenz G., Iwaszkiewicz J., Zoete V., Hailfinger S., Thome M. Monoubiquitination and activity of the paracaspase MALT1 requires glutamate 549 in the dimerization interface. PLOS ONE 2013, 8:e72051.
    • (2013) PLOS ONE , vol.8 , pp. e72051
    • Cabalzar, K.1    Pelzer, C.2    Wolf, A.3    Lenz, G.4    Iwaszkiewicz, J.5    Zoete, V.6    Hailfinger, S.7    Thome, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.