Tanshinone i induces cyclin D1 proteasomal degradation in an ERK1/2 dependent way in human colorectal cancer cells

Fitoterapia

Volumn 101, Issue , 2015, Pages 162-168

  Kim, Mi Kyoung ^a   Park, Gwang Hun ^a   Eo, Hyun Ji ^a   Song, Hun Min ^a   Lee, Jin Wook ^a   Kwon, Min Ji ^a   Koo, Jin Suk ^a   Jeong, Jin Boo ^a  

^a Andong National University   (South Korea)

Author keywords

Cancer chemoprevention; Colorectal cancer; Cyclin D1; Danshen; Tanshinone I

Indexed keywords

ALANINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIN D1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEASOME; TANSHINONE I; THREONINE; ABIETANE DERIVATIVE; ANTINEOPLASTIC AGENT; CCND1 PROTEIN, HUMAN; TANSHINONE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CELL GROWTH; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; HCT116 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; PHOSPHORYLATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; CELL PROLIFERATION; COLORECTAL TUMOR; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

SALVIA MILTIORRHIZA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN D1; DITERPENES, ABIETANE; DOWN-REGULATION; HUMANS; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 84921892789     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2015.01.010     Document Type: Article

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