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Volumn 54, Issue 2, 2015, Pages 179-193

Prediction of Drug Disposition in Diabetic Patients by Means of a Physiologically Based Pharmacokinetic Model

Author keywords

[No Author keywords available]

Indexed keywords

CHLORZOXAZONE; GLIBENCLAMIDE; GLIMEPIRIDE; LIVER ENZYME; METFORMIN; NISOLDIPINE; PHENAZONE; REPAGLINIDE; HYPOGLYCEMIC AGENTS;

EID: 84921809481     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.1007/s40262-014-0192-8     Document Type: Article
Times cited : (28)

References (86)
  • 1
    • 84863449162 scopus 로고    scopus 로고
    • Effect of diabetes mellitus on pharmacokinetic and pharmacodynamic properties of drugs
    • COI: 1:CAS:528:DC%2BC38Xht1ygur3L, PID: 22668340
    • Dostalek M, Akhlaghi F, Puzanovova M. Effect of diabetes mellitus on pharmacokinetic and pharmacodynamic properties of drugs. Clin Pharmacokinet. 2012;51(8):481–99. doi:10.2165/11631900-000000000-00000.
    • (2012) Clin Pharmacokinet. , vol.51 , Issue.8 , pp. 481-499
    • Dostalek, M.1    Akhlaghi, F.2    Puzanovova, M.3
  • 2
    • 0031864010 scopus 로고    scopus 로고
    • Drug administration in patients with diabetes mellitus: safety considerations
    • COI: 1:CAS:528:DyaK1cXktVSjsbw%3D, PID: 9638389
    • Gilbert RE, Cooper ME, Krum H. Drug administration in patients with diabetes mellitus: safety considerations. Drug Saf. 1998;18(6):441–55.
    • (1998) Drug Saf. , vol.18 , Issue.6 , pp. 441-455
    • Gilbert, R.E.1    Cooper, M.E.2    Krum, H.3
  • 3
    • 74249120678 scopus 로고    scopus 로고
    • Effect of obesity on the pharmacokinetics of drugs in humans
    • COI: 1:CAS:528:DC%2BC3cXjtV2isbg%3D, PID: 20067334
    • Hanley MJ, Abernethy DR, Greenblatt DJ. Effect of obesity on the pharmacokinetics of drugs in humans. Clin Pharmacokinet. 2010;49(2):71–87. doi:10.2165/11318100-000000000-00000.
    • (2010) Clin Pharmacokinet. , vol.49 , Issue.2 , pp. 71-87
    • Hanley, M.J.1    Abernethy, D.R.2    Greenblatt, D.J.3
  • 4
    • 33645790070 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamic target attainment of ertapenem in normal-weight, obese, and extremely obese adults
    • COI: 1:CAS:528:DC%2BD28XjvFOku74%3D, PID: 16569832
    • Chen M, Nafziger AN, Drusano GL, Ma L, Bertino JS Jr. Comparative pharmacokinetics and pharmacodynamic target attainment of ertapenem in normal-weight, obese, and extremely obese adults. Antimicrob Agents Chemother. 2006;50(4):1222–7. doi:10.1128/AAC.50.4.1222-1227.2006.
    • (2006) Antimicrob Agents Chemother. , vol.50 , Issue.4 , pp. 1222-1227
    • Chen, M.1    Nafziger, A.N.2    Drusano, G.L.3    Ma, L.4    Bertino, J.S.5
  • 5
    • 0036042732 scopus 로고    scopus 로고
    • Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin
    • PID: 12203108
    • De Jonge ME, Mathot RA, Van Dam SM, Beijnen JH, Rodenhuis S. Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin. Cancer Chemother Pharmacol. 2002;50(3):251–5. doi:10.1007/s00280-002-0494-7.
    • (2002) Cancer Chemother Pharmacol. , vol.50 , Issue.3 , pp. 251-255
    • De Jonge, M.E.1    Mathot, R.A.2    Van Dam, S.M.3    Beijnen, J.H.4    Rodenhuis, S.5
  • 6
    • 0029662031 scopus 로고    scopus 로고
    • [13C] octanoic acid breath test for non-invasive assessment of gastric emptying in diabetic patients: validation and relationship to gastric symptoms and cardiovascular autonomic function
    • COI: 1:STN:280:DyaK28vhsVSntQ%3D%3D, PID: 8817107
    • Ziegler D, Schadewaldt P, Pour Mirza A, Piolot R, Schommartz B, Reinhardt M, et al. [13C] octanoic acid breath test for non-invasive assessment of gastric emptying in diabetic patients: validation and relationship to gastric symptoms and cardiovascular autonomic function. Diabetologia. 1996;39(7):823–30.
    • (1996) Diabetologia , vol.39 , Issue.7 , pp. 823-830
    • Ziegler, D.1    Schadewaldt, P.2    Pour Mirza, A.3    Piolot, R.4    Schommartz, B.5    Reinhardt, M.6
  • 7
    • 0033055448 scopus 로고    scopus 로고
    • Euglycaemic hyperinsulinaemia does not affect gastric emptying in type I and type II diabetes mellitus
    • COI: 1:CAS:528:DyaK1MXhvVGktL8%3D, PID: 10096791
    • Kong MF, King P, Macdonald IA, Blackshaw PE, Horowitz M, Perkins AC, et al. Euglycaemic hyperinsulinaemia does not affect gastric emptying in type I and type II diabetes mellitus. Diabetologia. 1999;42(3):365–72. doi:10.1007/s001250051164.
    • (1999) Diabetologia. , vol.42 , Issue.3 , pp. 365-372
    • Kong, M.F.1    King, P.2    Macdonald, I.A.3    Blackshaw, P.E.4    Horowitz, M.5    Perkins, A.C.6
  • 8
    • 0029971741 scopus 로고    scopus 로고
    • Rapid gastric emptying of a solid pancake meal in type II diabetic patients
    • COI: 1:STN:280:DyaK28zhtFSqsQ%3D%3D, PID: 8732711
    • Schwartz JG, Green GM, Guan D, McMahan CA, Phillips WT. Rapid gastric emptying of a solid pancake meal in type II diabetic patients. Diabetes Care. 1996;19(5):468–71.
    • (1996) Diabetes Care. , vol.19 , Issue.5 , pp. 468-471
    • Schwartz, J.G.1    Green, G.M.2    Guan, D.3    McMahan, C.A.4    Phillips, W.T.5
  • 9
    • 0029126551 scopus 로고
    • Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus
    • COI: 1:STN:280:DyaK2MzosF2gsA%3D%3D, PID: 7657103
    • Frank JW, Saslow SB, Camilleri M, Thomforde GM, Dinneen S, Rizza RA. Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus. Gastroenterology. 1995;109(3):755–65.
    • (1995) Gastroenterology. , vol.109 , Issue.3 , pp. 755-765
    • Frank, J.W.1    Saslow, S.B.2    Camilleri, M.3    Thomforde, G.M.4    Dinneen, S.5    Rizza, R.A.6
  • 10
    • 0029812278 scopus 로고    scopus 로고
    • Gastric emptying in diabetes: an overview
    • COI: 1:STN:280:DyaK2s%2FkvFOgtQ%3D%3D, PID: 8894465
    • Horowitz M, Wishart JM, Jones KL, Hebbard GS. Gastric emptying in diabetes: an overview. Diabet Med. 1996;13(9 Suppl 5):S16–22.
    • (1996) Diabet Med. , vol.13 , Issue.9 , pp. S16-S22
    • Horowitz, M.1    Wishart, J.M.2    Jones, K.L.3    Hebbard, G.S.4
  • 11
    • 34447331420 scopus 로고    scopus 로고
    • Gastric emptying in diabetic patients by the (13) C-octanoic acid breath test: role of insulin in gastric motility
    • COI: 1:CAS:528:DC%2BD2sXntFKjsLc%3D, PID: 17671762
    • Matsumoto M, Yoshimura R, Akiho H, Higuchi N, Kobayashi K, Matsui N, et al. Gastric emptying in diabetic patients by the (13) C-octanoic acid breath test: role of insulin in gastric motility. J Gastroenterol. 2007;42(6):469–74. doi:10.1007/s00535-007-2031-2.
    • (2007) J Gastroenterol. , vol.42 , Issue.6 , pp. 469-474
    • Matsumoto, M.1    Yoshimura, R.2    Akiho, H.3    Higuchi, N.4    Kobayashi, K.5    Matsui, N.6
  • 12
    • 0034016949 scopus 로고    scopus 로고
    • Evaluation of gut motility in type II diabetes by the radiopaque marker method
    • COI: 1:STN:280:DC%2BD3c3ot12qtw%3D%3D, PID: 10824881
    • Iida M, Ikeda M, Kishimoto M, Tsujino T, Kaneto H, Matsuhisa M, et al. Evaluation of gut motility in type II diabetes by the radiopaque marker method. J Gastroenterol Hepatol. 2000;15(4):381–5.
    • (2000) J Gastroenterol Hepatol. , vol.15 , Issue.4 , pp. 381-385
    • Iida, M.1    Ikeda, M.2    Kishimoto, M.3    Tsujino, T.4    Kaneto, H.5    Matsuhisa, M.6
  • 13
    • 0017312230 scopus 로고
    • Small intestinal transit in diabetics
    • COI: 1:STN:280:DyaE2s%2Fks1Clsg%3D%3D, PID: 990859
    • Scarpello JH, Greaves M, Sladen GE. Small intestinal transit in diabetics. Br Med J. 1976;2(6046):1225–6.
    • (1976) Br Med J. , vol.2 , Issue.6046 , pp. 1225-1226
    • Scarpello, J.H.1    Greaves, M.2    Sladen, G.E.3
  • 14
    • 79958811096 scopus 로고    scopus 로고
    • Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
    • COI: 1:CAS:528:DC%2BC3MXnsFOhsb0%3D, PID: 21323901
    • Dostalek M, Court MH, Yan B, Akhlaghi F. Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus. Br J Pharmacol. 2011;163(5):937–47. doi:10.1111/j.1476-5381.2011.01270.x.
    • (2011) Br J Pharmacol. , vol.163 , Issue.5 , pp. 937-947
    • Dostalek, M.1    Court, M.H.2    Yan, B.3    Akhlaghi, F.4
  • 15
    • 84864775547 scopus 로고    scopus 로고
    • Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes
    • COI: 1:CAS:528:DC%2BC38XhsVCru7vP, PID: 22775412
    • Dostalek M, Sam WJ, Paryani KR, Macwan JS, Gohh RY, Akhlaghi F. Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes. Clin Pharmacokinet. 2012;51(9):591–606. doi:10.2165/11632690-000000000-00000.
    • (2012) Clin Pharmacokinet. , vol.51 , Issue.9 , pp. 591-606
    • Dostalek, M.1    Sam, W.J.2    Paryani, K.R.3    Macwan, J.S.4    Gohh, R.Y.5    Akhlaghi, F.6
  • 16
    • 33744987368 scopus 로고    scopus 로고
    • Cardiovascular risk factors and disease management in type 2 diabetic patients with diabetic nephropathy
    • PID: 16505495
    • Sasso FC, De Nicola L, Carbonara O, Nasti R, Minutolo R, Salvatore T, et al. Cardiovascular risk factors and disease management in type 2 diabetic patients with diabetic nephropathy. Diabetes Care. 2006;29(3):498–503.
    • (2006) Diabetes Care. , vol.29 , Issue.3 , pp. 498-503
    • Sasso, F.C.1    De Nicola, L.2    Carbonara, O.3    Nasti, R.4    Minutolo, R.5    Salvatore, T.6
  • 17
    • 70350219254 scopus 로고    scopus 로고
    • When to conduct a renal impairment study during drug development: US Food and Drug Administration perspective
    • COI: 1:CAS:528:DC%2BD1MXht1ymsrjM, PID: 19844224
    • Huang SM, Temple R, Xiao S, Zhang L, Lesko LJ. When to conduct a renal impairment study during drug development: US Food and Drug Administration perspective. Clin Pharmacol Ther. 2009;86(5):475–9. doi:10.1038/clpt.2009.190.
    • (2009) Clin Pharmacol Ther. , vol.86 , Issue.5 , pp. 475-479
    • Huang, S.M.1    Temple, R.2    Xiao, S.3    Zhang, L.4    Lesko, L.J.5
  • 18
    • 0028856712 scopus 로고
    • Kidney function and age are both predictors of pharmacokinetics of metformin
    • COI: 1:CAS:528:DyaK28XkslWguw%3D%3D, PID: 8626883
    • Sambol NC, Chiang J, Lin ET, Goodman AM, Liu CY, Benet LZ, et al. Kidney function and age are both predictors of pharmacokinetics of metformin. J Clin Pharmacol. 1995;35(11):1094–102.
    • (1995) J Clin Pharmacol. , vol.35 , Issue.11 , pp. 1094-1102
    • Sambol, N.C.1    Chiang, J.2    Lin, E.T.3    Goodman, A.M.4    Liu, C.Y.5    Benet, L.Z.6
  • 19
    • 0031974803 scopus 로고    scopus 로고
    • Rate of gastric emptying is a determinant of postprandial hypotension in non-insulin-dependent diabetes mellitus
    • COI: 1:STN:280:DyaK1c7ms1OltQ%3D%3D, PID: 9505868
    • Jones KL, Tonkin A, Horowitz M, Wishart JM, Carney BI, Guha S, et al. Rate of gastric emptying is a determinant of postprandial hypotension in non-insulin-dependent diabetes mellitus. Clin Sci (Lond). 1998;94(1):65–70.
    • (1998) Clin Sci (Lond). , vol.94 , Issue.1 , pp. 65-70
    • Jones, K.L.1    Tonkin, A.2    Horowitz, M.3    Wishart, J.M.4    Carney, B.I.5    Guha, S.6
  • 21
    • 79951765993 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetics in drug development and regulatory science
    • COI: 1:CAS:528:DC%2BC3MXisFOjurw%3D, PID: 20854171
    • Rowland M, Peck C, Tucker G. Physiologically-based pharmacokinetics in drug development and regulatory science. Annu Rev Pharmacol Toxicol. 2011;51:45–73. doi:10.1146/annurev-pharmtox-010510-100540.
    • (2011) Annu Rev Pharmacol Toxicol. , vol.51 , pp. 45-73
    • Rowland, M.1    Peck, C.2    Tucker, G.3
  • 22
    • 78951482203 scopus 로고    scopus 로고
    • Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review
    • COI: 1:STN:280:DC%2BC3M7ivFKisw%3D%3D, PID: 21191381
    • Zhao P, Zhang L, Grillo JA, Liu Q, Bullock JM, Moon YJ, et al. Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review. Clin Pharmacol Ther. 2011;89(2):259–67. doi:10.1038/clpt.2010.298.
    • (2011) Clin Pharmacol Ther. , vol.89 , Issue.2 , pp. 259-267
    • Zhao, P.1    Zhang, L.2    Grillo, J.A.3    Liu, Q.4    Bullock, J.M.5    Moon, Y.J.6
  • 23
    • 84875847254 scopus 로고    scopus 로고
    • A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women
    • COI: 1:CAS:528:DC%2BC3sXkslSkt7g%3D, PID: 23355638
    • Ke AB, Nallani SC, Zhao P, Rostami-Hodjegan A, Isoherranen N, Unadkat JD. A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women. Drug Metab Dispos. 2013;41(4):801–13. doi:10.1124/dmd.112.050161.
    • (2013) Drug Metab Dispos. , vol.41 , Issue.4 , pp. 801-813
    • Ke, A.B.1    Nallani, S.C.2    Zhao, P.3    Rostami-Hodjegan, A.4    Isoherranen, N.5    Unadkat, J.D.6
  • 24
    • 84867348647 scopus 로고    scopus 로고
    • A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4
    • PID: 22725721
    • Gaohua L, Abduljalil K, Jamei M, Johnson TN, Rostami-Hodjegan A. A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4. Br J Clin Pharmacol. 2012;74(5):873–85. doi:10.1111/j.1365-2125.2012.04363.x.
    • (2012) Br J Clin Pharmacol. , vol.74 , Issue.5 , pp. 873-885
    • Gaohua, L.1    Abduljalil, K.2    Jamei, M.3    Johnson, T.N.4    Rostami-Hodjegan, A.5
  • 25
    • 20644465189 scopus 로고    scopus 로고
    • Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs
    • PID: 15948934
    • Björkman S. Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs. Br J Clin Pharmacol. 2005;59(6):691–704. doi:10.1111/j.1365-2125.2004.02225.x.
    • (2005) Br J Clin Pharmacol. , vol.59 , Issue.6 , pp. 691-704
    • Björkman, S.1
  • 26
    • 0034820636 scopus 로고    scopus 로고
    • Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model
    • PID: 11745776
    • Björkman S, Wada DR, Berling BM, Benoni G. Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model. J Pharm Sci. 2001;90(9):1226–41. doi:10.1002/jps.1076.
    • (2001) J Pharm Sci. , vol.90 , Issue.9 , pp. 1226-1241
    • Björkman, S.1    Wada, D.R.2    Berling, B.M.3    Benoni, G.4
  • 27
    • 81255189066 scopus 로고    scopus 로고
    • Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance
    • COI: 1:CAS:528:DC%2BC38XjsF2kt7s%3D, PID: 22087867
    • Ghobadi C, Johnson TN, Aarabi M, Almond LM, Allabi AC, Rowland-Yeo K, et al. Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance. Clin Pharmacokinet. 2011;50(12):809–22. doi:10.2165/11594420-000000000-00000.
    • (2011) Clin Pharmacokinet. , vol.50 , Issue.12 , pp. 809-822
    • Ghobadi, C.1    Johnson, T.N.2    Aarabi, M.3    Almond, L.M.4    Allabi, A.C.5    Rowland-Yeo, K.6
  • 28
    • 77949381133 scopus 로고    scopus 로고
    • Predictions of metabolic drug-drug interactions using physiologically based modelling: two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil
    • COI: 1:CAS:528:DC%2BC3cXlsFCktLo%3D, PID: 20214408
    • Perdaems N, Blasco H, Vinson C, Chenel M, Whalley S, Cazade F, et al. Predictions of metabolic drug-drug interactions using physiologically based modelling: two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil. Clin Pharmacokinet. 2010;49(4):239–58. doi:10.2165/11318130-000000000-00000.
    • (2010) Clin Pharmacokinet. , vol.49 , Issue.4 , pp. 239-258
    • Perdaems, N.1    Blasco, H.2    Vinson, C.3    Chenel, M.4    Whalley, S.5    Cazade, F.6
  • 29
    • 0035478779 scopus 로고    scopus 로고
    • Predicting the impact of physiological and biochemical processes on oral drug bioavailability
    • COI: 1:CAS:528:DC%2BD3MXntVWku74%3D, PID: 11576695, (S0169409X0100179X)
    • Agoram B, Woltosz WS, Bolger MB. Predicting the impact of physiological and biochemical processes on oral drug bioavailability. Adv Drug Deliv Rev. 2001;50(Suppl 1):S41–67 (S0169409X0100179X).
    • (2001) Adv Drug Deliv Rev. , vol.50 , pp. S41-S67
    • Agoram, B.1    Woltosz, W.S.2    Bolger, M.B.3
  • 30
    • 68249152287 scopus 로고    scopus 로고
    • Mechanistic approaches to predicting oral drug absorption
    • COI: 1:CAS:528:DC%2BD1MXhtVWqs7rM, PID: 19381841
    • Huang W, Lee SL, Yu LX. Mechanistic approaches to predicting oral drug absorption. AAPS J. 2009;11(2):217–24. doi:10.1208/s12248-009-9098-z.
    • (2009) AAPS J. , vol.11 , Issue.2 , pp. 217-224
    • Huang, W.1    Lee, S.L.2    Yu, L.X.3
  • 31
    • 2942529161 scopus 로고    scopus 로고
    • Biowaiver extension potential to BCS Class III high solubility-low permeability drugs: bridging evidence for metformin immediate-release tablet
    • COI: 1:CAS:528:DC%2BD2cXkvV2ju7Y%3D, PID: 15196586
    • Cheng CL, Yu LX, Lee HL, Yang CY, Lue CS, Chou CH. Biowaiver extension potential to BCS Class III high solubility-low permeability drugs: bridging evidence for metformin immediate-release tablet. Eur J Pharm Sci. 2004;22(4):297–304. doi:10.1016/j.ejps.2004.03.016.
    • (2004) Eur J Pharm Sci. , vol.22 , Issue.4 , pp. 297-304
    • Cheng, C.L.1    Yu, L.X.2    Lee, H.L.3    Yang, C.Y.4    Lue, C.S.5    Chou, C.H.6
  • 32
    • 0030747422 scopus 로고    scopus 로고
    • Pharmacokinetics of the controlled-release nisoldipine coat-core tablet formulation
    • COI: 1:CAS:528:DC%2BD2sXhtVWlur7K, PID: 9266290
    • Heinig R, Ahr G, Hayauchi Y, Kuhlmann J. Pharmacokinetics of the controlled-release nisoldipine coat-core tablet formulation. Int J Clin Pharmacol Ther. 1997;35(8):341–51.
    • (1997) Int J Clin Pharmacol Ther. , vol.35 , Issue.8 , pp. 341-351
    • Heinig, R.1    Ahr, G.2    Hayauchi, Y.3    Kuhlmann, J.4
  • 33
    • 80052002510 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction
    • COI: 1:CAS:528:DC%2BC3MXhs1ekurrN, PID: 21632965
    • Gertz M, Houston JB, Galetin A. Physiologically based pharmacokinetic modeling of intestinal first-pass metabolism of CYP3A substrates with high intestinal extraction. Drug Metab Dispos. 2011;39(9):1633–42. doi:10.1124/dmd.111.039248.
    • (2011) Drug Metab Dispos. , vol.39 , Issue.9 , pp. 1633-1642
    • Gertz, M.1    Houston, J.B.2    Galetin, A.3
  • 34
    • 34249107476 scopus 로고    scopus 로고
    • Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus
    • COI: 1:STN:280:DC%2BD2szgtVeisg%3D%3D, PID: 17433797
    • Triantafyllou K, Kalantzis C, Papadopoulos AA, Apostolopoulos P, Rokkas T, Kalantzis N, et al. Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus. Dig Liver Dis. 2007;39(6):575–80. doi:10.1016/j.dld.2007.01.024.
    • (2007) Dig Liver Dis. , vol.39 , Issue.6 , pp. 575-580
    • Triantafyllou, K.1    Kalantzis, C.2    Papadopoulos, A.A.3    Apostolopoulos, P.4    Rokkas, T.5    Kalantzis, N.6
  • 35
    • 0037720113 scopus 로고    scopus 로고
    • Colonic transit time in diabetic patients–comparison with healthy subjects and the effect of autonomic neuropathy
    • PID: 12728467
    • Jung HK, Kim DY, Moon IH, Hong YS. Colonic transit time in diabetic patients–comparison with healthy subjects and the effect of autonomic neuropathy. Yonsei Med J. 2003;44(2):265–72.
    • (2003) Yonsei Med J. , vol.44 , Issue.2 , pp. 265-272
    • Jung, H.K.1    Kim, D.Y.2    Moon, I.H.3    Hong, Y.S.4
  • 36
    • 84881006685 scopus 로고    scopus 로고
    • A mechanistic physiologically based pharmacokinetic-enzyme turnover model involving both intestine and liver to predict CYP3A induction-mediated drug-drug interactions
    • COI: 1:CAS:528:DC%2BC3sXptFCqtL0%3D, PID: 23760985
    • Guo H, Liu C, Li J, Zhang M, Hu M, Xu P, et al. A mechanistic physiologically based pharmacokinetic-enzyme turnover model involving both intestine and liver to predict CYP3A induction-mediated drug-drug interactions. J Pharm Sci. 2013;102(8):2819–36. doi:10.1002/jps.23613.
    • (2013) J Pharm Sci. , vol.102 , Issue.8 , pp. 2819-2836
    • Guo, H.1    Liu, C.2    Li, J.3    Zhang, M.4    Hu, M.5    Xu, P.6
  • 37
    • 84868575110 scopus 로고    scopus 로고
    • Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling
    • COI: 1:CAS:528:DC%2BC38Xhs1ajtb3L, PID: 23085739
    • Li GF, Wang K, Chen R, Zhao HR, Yang J, Zheng QS. Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling. Acta Pharmacol Sin. 2012;33(11):1359–71. doi:10.1038/aps.2012.103.
    • (2012) Acta Pharmacol Sin. , vol.33 , Issue.11 , pp. 1359-1371
    • Li, G.F.1    Wang, K.2    Chen, R.3    Zhao, H.R.4    Yang, J.5    Zheng, Q.S.6
  • 38
    • 80052262709 scopus 로고    scopus 로고
    • PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach
    • Poulin P, Jones RD, Jones HM, Gibson CR, Rowland M, Chien JY, et al. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach. J Pharm Sci. Epub 2011 May 3. doi:10.1002/jps.22550
    • (2011) J Pharm Sci. Epub , pp. 3
    • Poulin, P.1    Jones, R.D.2    Jones, H.M.3    Gibson, C.R.4    Rowland, M.5    Chien, J.Y.6
  • 39
    • 33646124969 scopus 로고    scopus 로고
    • A novel strategy for physiologically based predictions of human pharmacokinetics
    • COI: 1:CAS:528:DC%2BD28Xlt1Kgsbo%3D, PID: 16640456
    • Jones HM, Parrott N, Jorga K, Lave T. A novel strategy for physiologically based predictions of human pharmacokinetics. Clin Pharmacokinet. 2006;45(5):511–42.
    • (2006) Clin Pharmacokinet. , vol.45 , Issue.5 , pp. 511-542
    • Jones, H.M.1    Parrott, N.2    Jorga, K.3    Lave, T.4
  • 40
    • 0028818229 scopus 로고
    • Species similarities and differences in pharmacokinetics
    • COI: 1:CAS:528:DyaK2MXovFGksbw%3D, PID: 8654187
    • Lin JH. Species similarities and differences in pharmacokinetics. Drug Metab Dispos. 1995;23(10):1008–21.
    • (1995) Drug Metab Dispos. , vol.23 , Issue.10 , pp. 1008-1021
    • Lin, J.H.1
  • 41
    • 80052267476 scopus 로고    scopus 로고
    • PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution
    • Jones RD, Jones HM, Rowland M, Gibson CR, Yates JW, Chien JY, et al. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution. J Pharm Sci. Epub 2011 Mar 30. doi:10.1002/jps.22553
    • (2011) J Pharm Sci. Epub , pp. 30
    • Jones, R.D.1    Jones, H.M.2    Rowland, M.3    Gibson, C.R.4    Yates, J.W.5    Chien, J.Y.6
  • 42
    • 21344469211 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases
    • COI: 1:CAS:528:DC%2BD2MXkvF2qtLs%3D, PID: 15858854
    • Rodgers T, Leahy D, Rowland M. Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases. J Pharm Sci. 2005;94(6):1259–76. doi:10.1002/jps.20322.
    • (2005) J Pharm Sci. , vol.94 , Issue.6 , pp. 1259-1276
    • Rodgers, T.1    Leahy, D.2    Rowland, M.3
  • 43
    • 84919681951 scopus 로고    scopus 로고
    • Combining the “bottom-up” and “top-down” approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data
    • Tsamandouras N, Rostami-Hodjegan A, Aarons L. Combining the “bottom-up” and “top-down” approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data. Br J Clin Pharmacol. Epub 2013 Sep 3. doi:10.1111/bcp.12234.
    • (2013) Br J Clin Pharmacol. Epub , pp. 3
    • Tsamandouras, N.1    Rostami-Hodjegan, A.2    Aarons, L.3
  • 44
    • 67649392513 scopus 로고    scopus 로고
    • A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of ‘bottom-up’ vs ‘top-down’ recognition of covariates
    • COI: 1:CAS:528:DC%2BD1MXks1Whu7o%3D, PID: 19252336, (JST.JSTAGE/dmpk/24.53)
    • Jamei M, Dickinson GL, Rostami-Hodjegan A. A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of ‘bottom-up’ vs ‘top-down’ recognition of covariates. Drug Metab Pharmacokinet. 2009;24(1):53–75 (JST.JSTAGE/dmpk/24.53).
    • (2009) Drug Metab Pharmacokinet. , vol.24 , Issue.1 , pp. 53-75
    • Jamei, M.1    Dickinson, G.L.2    Rostami-Hodjegan, A.3
  • 45
    • 33746893861 scopus 로고    scopus 로고
    • In silico modeling of non-linear drug absorption for the P-gp substrate talinolol and of consequences for the resulting pharmacodynamic effect
    • COI: 1:CAS:528:DC%2BD28XnvVyms7s%3D, PID: 16832615
    • Tubic M, Wagner D, Spahn-Langguth H, Bolger MB, Langguth P. In silico modeling of non-linear drug absorption for the P-gp substrate talinolol and of consequences for the resulting pharmacodynamic effect. Pharm Res. 2006;23(8):1712–20. doi:10.1007/s11095-006-9020-7.
    • (2006) Pharm Res. , vol.23 , Issue.8 , pp. 1712-1720
    • Tubic, M.1    Wagner, D.2    Spahn-Langguth, H.3    Bolger, M.B.4    Langguth, P.5
  • 46
    • 84858016380 scopus 로고    scopus 로고
    • In silico modeling for the nonlinear absorption kinetics of UK-343,664: a P-gp and CYP3A4 substrate
    • COI: 1:CAS:528:DC%2BC38XpslGgsg%3D%3D, PID: 22264132
    • Abuasal BS, Bolger MB, Walker DK, Kaddoumi A. In silico modeling for the nonlinear absorption kinetics of UK-343,664: a P-gp and CYP3A4 substrate. Mol Pharm. 2012;9(3):492–504. doi:10.1021/mp200275j.
    • (2012) Mol Pharm. , vol.9 , Issue.3 , pp. 492-504
    • Abuasal, B.S.1    Bolger, M.B.2    Walker, D.K.3    Kaddoumi, A.4
  • 48
    • 54349113314 scopus 로고    scopus 로고
    • Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction
    • COI: 1:CAS:528:DC%2BD1cXhtlWiu77F, PID: 18669588
    • Shou M, Hayashi M, Pan Y, Xu Y, Morrissey K, Xu L, et al. Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction. Drug Metab Dispos. 2008;36(11):2355–70. doi:10.1124/dmd.108.020602.
    • (2008) Drug Metab Dispos. , vol.36 , Issue.11 , pp. 2355-2370
    • Shou, M.1    Hayashi, M.2    Pan, Y.3    Xu, Y.4    Morrissey, K.5    Xu, L.6
  • 49
    • 0028340450 scopus 로고
    • Determination of the enantiomers of nisoldipine in human plasma using high-performance liquid chromatography on a chiral stationary phase and gas chromatography with mass-selective detection
    • COI: 1:CAS:528:DyaK2cXksV2msbc%3D, PID: 8081476
    • Heinig R, Muschalek V, Ahr G. Determination of the enantiomers of nisoldipine in human plasma using high-performance liquid chromatography on a chiral stationary phase and gas chromatography with mass-selective detection. J Chromatogr B Biomed Appl. 1994;655(2):286–92.
    • (1994) J Chromatogr B Biomed Appl. , vol.655 , Issue.2 , pp. 286-292
    • Heinig, R.1    Muschalek, V.2    Ahr, G.3
  • 50
    • 0036460044 scopus 로고    scopus 로고
    • Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD38XpsFSgtrY%3D, PID: 12483453
    • Marques MP, Coelho EB, Dos Santos NA, Geleilete TJ, Lanchote VL. Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus. Eur J Clin Pharmacol. 2002;58(9):607–14. doi:10.1007/s00228-002-0528-4.
    • (2002) Eur J Clin Pharmacol. , vol.58 , Issue.9 , pp. 607-614
    • Marques, M.P.1    Coelho, E.B.2    Dos Santos, N.A.3    Geleilete, T.J.4    Lanchote, V.L.5
  • 51
    • 0032976307 scopus 로고    scopus 로고
    • Repaglinide pharmacokinetics in healthy young adult and elderly subjects
    • COI: 1:CAS:528:DyaK1MXjsl2mt7g%3D, PID: 10363735
    • Hatorp V, Huang WC, Strange P. Repaglinide pharmacokinetics in healthy young adult and elderly subjects. Clin Ther. 1999;21(4):702–10. doi:10.1016/S0149-2918(00)88321-6.
    • (1999) Clin Ther. , vol.21 , Issue.4 , pp. 702-710
    • Hatorp, V.1    Huang, W.C.2    Strange, P.3
  • 52
    • 0035030427 scopus 로고    scopus 로고
    • Single- and multiple-dose pharmacokinetics of repaglinide in patients with type 2 diabetes and renal impairment
    • COI: 1:CAS:528:DC%2BD3MXjtFOqtrw%3D, PID: 11417447
    • Schumacher S, Abbasi I, Weise D, Hatorp V, Sattler K, Sieber J, et al. Single- and multiple-dose pharmacokinetics of repaglinide in patients with type 2 diabetes and renal impairment. Eur J Clin Pharmacol. 2001;57(2):147–52.
    • (2001) Eur J Clin Pharmacol. , vol.57 , Issue.2 , pp. 147-152
    • Schumacher, S.1    Abbasi, I.2    Weise, D.3    Hatorp, V.4    Sattler, K.5    Sieber, J.6
  • 53
    • 0033323986 scopus 로고    scopus 로고
    • Pharmacokinetic profiles of repaglinide in elderly subjects with type 2 diabetes
    • COI: 1:CAS:528:DyaK1MXisVyrtbk%3D, PID: 10199798
    • Hatorp V, Huang WC, Strange P. Pharmacokinetic profiles of repaglinide in elderly subjects with type 2 diabetes. J Clin Endocrinol Metab. 1999;84(4):1475–8. doi:10.1210/jcem.84.4.5726.
    • (1999) J Clin Endocrinol Metab. , vol.84 , Issue.4 , pp. 1475-1478
    • Hatorp, V.1    Huang, W.C.2    Strange, P.3
  • 54
    • 0028575332 scopus 로고
    • Dose linearity assessment of glimepiride (Amaryl) tablets in healthy volunteers
    • COI: 1:CAS:528:DyaK2MXnvFeqsL8%3D, PID: 12369757
    • Malerczyk V, Badian M, Korn A, Lehr KH, Waldhausl W. Dose linearity assessment of glimepiride (Amaryl) tablets in healthy volunteers. Drug Metabol Drug Interact. 1994;11(4):341–57.
    • (1994) Drug Metabol Drug Interact. , vol.11 , Issue.4 , pp. 341-357
    • Malerczyk, V.1    Badian, M.2    Korn, A.3    Lehr, K.H.4    Waldhausl, W.5
  • 55
    • 79955712959 scopus 로고    scopus 로고
    • Assessment of the pharmacokinetic interaction between the novel DPP-4 inhibitor linagliptin and a sulfonylurea, glyburide, in healthy subjects
    • COI: 1:CAS:528:DC%2BC3MXpvVyjtbk%3D, PID: 21084763
    • Graefe-Mody U, Rose P, Ring A, Zander K, Iovino M, Woerle HJ. Assessment of the pharmacokinetic interaction between the novel DPP-4 inhibitor linagliptin and a sulfonylurea, glyburide, in healthy subjects. Drug Metab Pharmacokinet. 2011;26(2):123–9. doi:10.2133/dmpk.DMPK-10-RG-091.
    • (2011) Drug Metab Pharmacokinet. , vol.26 , Issue.2 , pp. 123-129
    • Graefe-Mody, U.1    Rose, P.2    Ring, A.3    Zander, K.4    Iovino, M.5    Woerle, H.J.6
  • 56
    • 0346362456 scopus 로고    scopus 로고
    • Glimepiride pharmacokinetics in obese versus non-obese diabetic patients
    • COI: 1:CAS:528:DC%2BD2cXlvVCntQ%3D%3D, PID: 14742789
    • Shukla UA, Chi EM, Lehr KH. Glimepiride pharmacokinetics in obese versus non-obese diabetic patients. Ann Pharmacother. 2004;38(1):30–5. doi:10.1345/aph.1C397.
    • (2004) Ann Pharmacother. , vol.38 , Issue.1 , pp. 30-35
    • Shukla, U.A.1    Chi, E.M.2    Lehr, K.H.3
  • 57
    • 0028587589 scopus 로고
    • Absolute bioavailability of glimepiride (Amaryl) after oral administration
    • COI: 1:CAS:528:DyaK2MXnvFeqsL4%3D, PID: 12369756
    • Badian M, Korn A, Lehr KH, Malerczyk V, Waldhausl W. Absolute bioavailability of glimepiride (Amaryl) after oral administration. Drug Metabol Drug Interact. 1994;11(4):331–9.
    • (1994) Drug Metabol Drug Interact. , vol.11 , Issue.4 , pp. 331-339
    • Badian, M.1    Korn, A.2    Lehr, K.H.3    Malerczyk, V.4    Waldhausl, W.5
  • 58
    • 0034467568 scopus 로고    scopus 로고
    • Effects and pharmacokinetics of oral glibenclamide and glipizide in Caucasian and Chinese patients with type-2 diabetes
    • COI: 1:CAS:528:DC%2BD3MXlt1Kmuw%3D%3D, PID: 11214781
    • Jonsson A, Chan JC, Rydberg T, Vaaler S, Hallengren B, Cockram CS, et al. Effects and pharmacokinetics of oral glibenclamide and glipizide in Caucasian and Chinese patients with type-2 diabetes. Eur J Clin Pharmacol. 2000;56(9–10):711–4.
    • (2000) Eur J Clin Pharmacol. , vol.56 , Issue.9-10 , pp. 711-714
    • Jonsson, A.1    Chan, J.C.2    Rydberg, T.3    Vaaler, S.4    Hallengren, B.5    Cockram, C.S.6
  • 59
    • 47549105349 scopus 로고    scopus 로고
    • Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXhtVynu7fE, PID: 18793589
    • Serra D, He YL, Bullock J, Riviere GJ, Balez S, Schwartz S, et al. Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes. Int J Clin Pharmacol Ther. 2008;46(7):349–64.
    • (2008) Int J Clin Pharmacol Ther. , vol.46 , Issue.7 , pp. 349-364
    • Serra, D.1    He, Y.L.2    Bullock, J.3    Riviere, G.J.4    Balez, S.5    Schwartz, S.6
  • 60
    • 0028997743 scopus 로고
    • Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1
    • COI: 1:CAS:528:DyaK2MXntVSmt74%3D, PID: 7550365
    • Ono S, Hatanaka T, Hotta H, Tsutsui M, Satoh T, Gonzalez FJ. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1. Pharmacogenetics. 1995;5(3):143–50.
    • (1995) Pharmacogenetics. , vol.5 , Issue.3 , pp. 143-150
    • Ono, S.1    Hatanaka, T.2    Hotta, H.3    Tsutsui, M.4    Satoh, T.5    Gonzalez, F.J.6
  • 61
    • 0037241174 scopus 로고    scopus 로고
    • Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans
    • COI: 1:CAS:528:DC%2BD3sXhsFOkurg%3D, PID: 12534643
    • Wang Z, Hall SD, Maya JF, Li L, Asghar A, Gorski JC. Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans. Br J Clin Pharmacol. 2003;55(1):77–85.
    • (2003) Br J Clin Pharmacol. , vol.55 , Issue.1 , pp. 77-85
    • Wang, Z.1    Hall, S.D.2    Maya, J.F.3    Li, L.4    Asghar, A.5    Gorski, J.C.6
  • 62
    • 0030443768 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus
    • COI: 1:CAS:528:DyaK2sXkvVamtw%3D%3D, PID: 8973990
    • Sambol NC, Chiang J, O’Conner M, Liu CY, Lin ET, Goodman AM, et al. Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus. J Clin Pharmacol. 1996;36(11):1012–21.
    • (1996) J Clin Pharmacol. , vol.36 , Issue.11 , pp. 1012-1021
    • Sambol, N.C.1    Chiang, J.2    O’Conner, M.3    Liu, C.Y.4    Lin, E.T.5    Goodman, A.M.6
  • 63
    • 84255204816 scopus 로고    scopus 로고
    • Transporter-mediated drug-drug interactions with oral antidiabetic drugs
    • COI: 1:CAS:528:DC%2BC3MXhsVKju73N, PID: 24309303
    • Klatt S, Fromm MF, Konig J. Transporter-mediated drug-drug interactions with oral antidiabetic drugs. Pharmaceutics. 2011;3(4):680–705. doi:10.3390/pharmaceutics3040680.
    • (2011) Pharmaceutics. , vol.3 , Issue.4 , pp. 680-705
    • Klatt, S.1    Fromm, M.F.2    Konig, J.3
  • 64
    • 84862113849 scopus 로고    scopus 로고
    • Combined contributions of impaired hepatic CYP2C11 and intestinal breast cancer resistance protein activities and expression to increased oral glibenclamide exposure in rats with streptozotocin-induced diabetes mellitus
    • PID: 22393122
    • Liu H, Liu L, Li J, Mei D, Duan R, Hu N, et al. Combined contributions of impaired hepatic CYP2C11 and intestinal breast cancer resistance protein activities and expression to increased oral glibenclamide exposure in rats with streptozotocin-induced diabetes mellitus. Drug Metab Dispos. 2012;40(6):1104–12. doi:10.1124/dmd.111.043513.
    • (2012) Drug Metab Dispos. , vol.40 , Issue.6 , pp. 1104-1112
    • Liu, H.1    Liu, L.2    Li, J.3    Mei, D.4    Duan, R.5    Hu, N.6
  • 65
    • 79251577704 scopus 로고    scopus 로고
    • Customized in silico population mimics actual population in docetaxel population pharmacokinetic analysis
    • COI: 1:CAS:528:DC%2BC3MXht1Crs74%3D, PID: 20803616
    • Hudachek SF, Gustafson DL. Customized in silico population mimics actual population in docetaxel population pharmacokinetic analysis. J Pharm Sci. 2011;100(3):1156–66. doi:10.1002/jps.22322.
    • (2011) J Pharm Sci. , vol.100 , Issue.3 , pp. 1156-1166
    • Hudachek, S.F.1    Gustafson, D.L.2
  • 66
    • 0035977911 scopus 로고    scopus 로고
    • Modelling and simulation of variability and uncertainty in toxicokinetics and pharmacokinetics
    • COI: 1:CAS:528:DC%2BD3MXivFejt7k%3D, PID: 11323201
    • Nestorov I. Modelling and simulation of variability and uncertainty in toxicokinetics and pharmacokinetics. Toxicol Lett. 2001;120(1–3):411–20. doi:10.1016/S0378-4274(01)00273-9.
    • (2001) Toxicol Lett. , vol.120 , Issue.1-3 , pp. 411-420
    • Nestorov, I.1
  • 67
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • COI: 1:STN:280:DyaK3szptFaqsg%3D%3D, PID: 8378254
    • Davies B, Morris T. Physiological parameters in laboratory animals and humans. Pharm Res. 1993;10(7):1093–5.
    • (1993) Pharm Res. , vol.10 , Issue.7 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 68
    • 0030806348 scopus 로고    scopus 로고
    • Physiological parameter values for physiologically based pharmacokinetic models
    • COI: 1:CAS:528:DyaK2sXltl2itrk%3D, PID: 9249929
    • Brown RP, Delp MD, Lindstedt SL, Rhomberg LR, Beliles RP. Physiological parameter values for physiologically based pharmacokinetic models. Toxicol Ind Health. 1997;13(4):407–84.
    • (1997) Toxicol Ind Health. , vol.13 , Issue.4 , pp. 407-484
    • Brown, R.P.1    Delp, M.D.2    Lindstedt, S.L.3    Rhomberg, L.R.4    Beliles, R.P.5
  • 69
    • 0036144815 scopus 로고    scopus 로고
    • Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution
    • COI: 1:CAS:528:DC%2BD38Xmslyhtg%3D%3D, PID: 11782904
    • Poulin P, Theil FP. Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution. J Pharm Sci. 2002;91(1):129–56. doi:10.1002/jps.10005.
    • (2002) J Pharm Sci. , vol.91 , Issue.1 , pp. 129-156
    • Poulin, P.1    Theil, F.P.2
  • 70
    • 84876483882 scopus 로고    scopus 로고
    • Mechanistic modeling to predict the transporter- and enzyme-mediated drug-drug interactions of repaglinide
    • COI: 1:CAS:528:DC%2BC3sXlvVKjug%3D%3D, PID: 23307347
    • Varma MV, Lai Y, Kimoto E, Goosen TC, El-Kattan AF, Kumar V. Mechanistic modeling to predict the transporter- and enzyme-mediated drug-drug interactions of repaglinide. Pharm Res. 2013;30(4):1188–99. doi:10.1007/s11095-012-0956-5.
    • (2013) Pharm Res. , vol.30 , Issue.4 , pp. 1188-1199
    • Varma, M.V.1    Lai, Y.2    Kimoto, E.3    Goosen, T.C.4    El-Kattan, A.F.5    Kumar, V.6
  • 71
    • 0019467428 scopus 로고
    • Metformin kinetics in healthy subjects and in patients with diabetes mellitus
    • COI: 1:CAS:528:DyaL3MXls1Wltbc%3D, PID: 7306436
    • Tucker GT, Casey C, Phillips PJ, Connor H, Ward JD, Woods HF. Metformin kinetics in healthy subjects and in patients with diabetes mellitus. Br J Clin Pharmacol. 1981;12(2):235–46.
    • (1981) Br J Clin Pharmacol. , vol.12 , Issue.2 , pp. 235-246
    • Tucker, G.T.1    Casey, C.2    Phillips, P.J.3    Connor, H.4    Ward, J.D.5    Woods, H.F.6
  • 72
    • 84872689874 scopus 로고    scopus 로고
    • Application of hybrid approach based on empirical and physiological concept for predicting pharmacokinetics in humans–usefulness of exponent on prospective evaluation of predictability
    • COI: 1:CAS:528:DC%2BC3sXitlGitrw%3D, PID: 23209193
    • Sayama H, Komura H, Kogayu M. Application of hybrid approach based on empirical and physiological concept for predicting pharmacokinetics in humans–usefulness of exponent on prospective evaluation of predictability. Drug Metab Dispos. 2013;41(2):498–507. doi:10.1124/dmd.112.048819.
    • (2013) Drug Metab Dispos. , vol.41 , Issue.2 , pp. 498-507
    • Sayama, H.1    Komura, H.2    Kogayu, M.3
  • 73
    • 84885141801 scopus 로고    scopus 로고
    • Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions
    • COI: 1:CAS:528:DC%2BC3sXhtFygtLjM, PID: 23806476
    • Greupink R, Schreurs M, Benne MS, Huisman MT, Russel FG. Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions. Eur J Pharm Sci. 2013;49(5):819–28. doi:10.1016/j.ejps.2013.06.009.
    • (2013) Eur J Pharm Sci. , vol.49 , Issue.5 , pp. 819-828
    • Greupink, R.1    Schreurs, M.2    Benne, M.S.3    Huisman, M.T.4    Russel, F.G.5
  • 74
    • 0032214518 scopus 로고    scopus 로고
    • Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin
    • COI: 1:CAS:528:DyaK1MXks1ersQ%3D%3D, PID: 9885303
    • Frick A, Moller H, Wirbitzki E. Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin. Eur J Pharm Biopharm. 1998;46(3):305–11. doi:10.1016/S0939-6411(98)00041-1.
    • (1998) Eur J Pharm Biopharm. , vol.46 , Issue.3 , pp. 305-311
    • Frick, A.1    Moller, H.2    Wirbitzki, E.3
  • 75
    • 0029855969 scopus 로고    scopus 로고
    • Comparison between permeability coefficients in rat and human jejunum
    • COI: 1:CAS:528:DyaK28XmtFWltLg%3D, PID: 8893271
    • Fagerholm U, Johansson M, Lennernas H. Comparison between permeability coefficients in rat and human jejunum. Pharm Res. 1996;13(9):1336–42.
    • (1996) Pharm Res. , vol.13 , Issue.9 , pp. 1336-1342
    • Fagerholm, U.1    Johansson, M.2    Lennernas, H.3
  • 76
    • 0030947756 scopus 로고    scopus 로고
    • Concentration-effect relations of glibenclamide and its active metabolites in man: modelling of pharmacokinetics and pharmacodynamics
    • COI: 1:CAS:528:DyaK2sXjtlWisrY%3D, PID: 9146849
    • Rydberg T, Jonsson A, Karlsson MO, Melander A. Concentration-effect relations of glibenclamide and its active metabolites in man: modelling of pharmacokinetics and pharmacodynamics. Br J Clin Pharmacol. 1997;43(4):373–81.
    • (1997) Br J Clin Pharmacol. , vol.43 , Issue.4 , pp. 373-381
    • Rydberg, T.1    Jonsson, A.2    Karlsson, M.O.3    Melander, A.4
  • 77
    • 84857239735 scopus 로고    scopus 로고
    • Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation
    • COI: 1:CAS:528:DC%2BC38XitF2rsbc%3D, PID: 22232759
    • Zhao P, Vieira Mde L, Grillo JA, Song P, Wu TC, Zheng JH, et al. Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation. J Clin Pharmacol. 2012;52(1 Suppl):91S–108S. doi:10.1177/0091270011415528.
    • (2012) J Clin Pharmacol , vol.52 , Issue.1 , pp. 91S-108S
    • Zhao, P.1    Vieira Mde, L.2    Grillo, J.A.3    Song, P.4    Wu, T.C.5    Zheng, J.H.6
  • 78
    • 0019783320 scopus 로고
    • Clinical pharmacokinetics of sulphonylurea hypoglycaemic drugs
    • COI: 1:CAS:528:DyaL3MXksFCnsLs%3D, PID: 7016385
    • Balant L. Clinical pharmacokinetics of sulphonylurea hypoglycaemic drugs. Clin Pharmacokinet. 1981;6(3):215–41.
    • (1981) Clin Pharmacokinet. , vol.6 , Issue.3 , pp. 215-241
    • Balant, L.1
  • 79
    • 0030894106 scopus 로고    scopus 로고
    • Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species
    • COI: 1:CAS:528:DyaK2sXis1KgtLk%3D, PID: 9113344
    • Court MH, Von Moltke LL, Shader RI, Greenblatt DJ. Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species. Biopharm Drug Dispos. 1997;18(3):213–26.
    • (1997) Biopharm Drug Dispos. , vol.18 , Issue.3 , pp. 213-226
    • Court, M.H.1    Von Moltke, L.L.2    Shader, R.I.3    Greenblatt, D.J.4
  • 80
    • 0030918716 scopus 로고    scopus 로고
    • Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs
    • COI: 1:CAS:528:DyaK2sXisVOqtrw%3D, PID: 9145383
    • Lave T, Dupin S, Schmitt C, Chou RC, Jaeck D, Coassolo P. Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs. J Pharm Sci. 1997;86(5):584–90. doi:10.1021/js960440h.
    • (1997) J Pharm Sci. , vol.86 , Issue.5 , pp. 584-590
    • Lave, T.1    Dupin, S.2    Schmitt, C.3    Chou, R.C.4    Jaeck, D.5    Coassolo, P.6
  • 81
    • 0028886355 scopus 로고
    • Comparison of the kinetics of glyburide and its active metabolites in humans
    • COI: 1:CAS:528:DyaK28XisFyh, PID: 8576296
    • Rydberg T, Jonsson A, Melander A. Comparison of the kinetics of glyburide and its active metabolites in humans. J Clin Pharm Ther. 1995;20(5):283–95.
    • (1995) J Clin Pharm Ther. , vol.20 , Issue.5 , pp. 283-295
    • Rydberg, T.1    Jonsson, A.2    Melander, A.3
  • 82
    • 0346731058 scopus 로고    scopus 로고
    • Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
    • COI: 1:CAS:528:DC%2BD3sXpslOit7w%3D, PID: 14610624
    • Kramer I, Dalhoff K, Clemmesen JO, Loft S, Poulsen HE. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans. Eur J Clin Pharmacol. 2003;59(10):775–8. doi:10.1007/s00228-003-0695-y.
    • (2003) Eur J Clin Pharmacol. , vol.59 , Issue.10 , pp. 775-778
    • Kramer, I.1    Dalhoff, K.2    Clemmesen, J.O.3    Loft, S.4    Poulsen, H.E.5
  • 83
    • 77953737073 scopus 로고    scopus 로고
    • Prediction of human intestinal first-pass metabolism of 25 CYP3A substrates from in vitro clearance and permeability data
    • COI: 1:CAS:528:DC%2BC3cXos1Klsb8%3D, PID: 20368326
    • Gertz M, Harrison A, Houston JB, Galetin A. Prediction of human intestinal first-pass metabolism of 25 CYP3A substrates from in vitro clearance and permeability data. Drug Metab Dispos. 2010;38(7):1147–58. doi:10.1124/dmd.110.032649.
    • (2010) Drug Metab Dispos. , vol.38 , Issue.7 , pp. 1147-1158
    • Gertz, M.1    Harrison, A.2    Houston, J.B.3    Galetin, A.4
  • 84
    • 0029683112 scopus 로고    scopus 로고
    • Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation
    • COI: 1:CAS:528:DyaK28XksFemurg%3D, PID: 8681486
    • Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M. Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther. 1996;59(6):613–23. doi:10.1016/S0009-9236(96)90001-6.
    • (1996) Clin Pharmacol Ther. , vol.59 , Issue.6 , pp. 613-623
    • Engel, G.1    Hofmann, U.2    Heidemann, H.3    Cosme, J.4    Eichelbaum, M.5
  • 85
    • 0037403950 scopus 로고    scopus 로고
    • Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitro
    • COI: 1:CAS:528:DC%2BD3sXjt1Ggt7s%3D, PID: 12695346
    • Naritomi Y, Terashita S, Kagayama A, Sugiyama Y. Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitro. Drug Metab Dispos. 2003;31(5):580–8.
    • (2003) Drug Metab Dispos. , vol.31 , Issue.5 , pp. 580-588
    • Naritomi, Y.1    Terashita, S.2    Kagayama, A.3    Sugiyama, Y.4
  • 86
    • 0030781510 scopus 로고    scopus 로고
    • Prediction of species differences (rats, dogs, humans) in the in vivo metabolic clearance of YM796 by the liver from in vitro data
    • COI: 1:CAS:528:DyaK2sXnsV2nu74%3D, PID: 9353358
    • Iwatsubo T, Suzuki H, Sugiyama Y. Prediction of species differences (rats, dogs, humans) in the in vivo metabolic clearance of YM796 by the liver from in vitro data. J Pharmacol Exp Ther. 1997;283(2):462–9.
    • (1997) J Pharmacol Exp Ther. , vol.283 , Issue.2 , pp. 462-469
    • Iwatsubo, T.1    Suzuki, H.2    Sugiyama, Y.3


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