Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.

Journal of clinical pharmacology

Volumn 52, Issue 1 Suppl, 2012, Pages

  Zhao, Ping ^a   Vieira, Manuela de L T ^b   Grillo, Joseph A ^b   Song, Pengfei ^b   Wu, Ta Chen ^b   Zheng, Jenny H ^b   Arya, Vikram ^b   Berglund, Eva Gil ^b   Atkinson, Arthur J ^b   Sugiyama, Yuichi ^b   Pang, K Sandy ^b   Reynolds, Kellie S ^b   Abernethy, Darrell R ^b   Zhang, Lei ^b   Lesko, Lawrence J ^b   Huang, Shiew Mei ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMIC ACID DERIVATIVE; KETOLIDE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; PURINE DERIVATIVE; REPAGLINIDE; SILDENAFIL; SULFONE; TELITHROMYCIN;

AREA UNDER THE CURVE; ARTICLE; BIOLOGICAL MODEL; BLOOD; CHRONIC DISEASE; COMPUTER SIMULATION; DRUG INTERACTION; HUMAN; KIDNEY DISEASE; METABOLISM;

AREA UNDER CURVE; CARBAMATES; CHRONIC DISEASE; COMPUTER SIMULATION; DRUG INTERACTIONS; HUMANS; KETOLIDES; KIDNEY DISEASES; MODELS, BIOLOGICAL; PIPERAZINES; PIPERIDINES; PURINES; SULFONES;

MLCS; MLOWN;

EID: 84857239735     PISSN: None     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011415528     Document Type: Article

References (0)