Phosphodiesterase 1A modulates cystogenesis in zebrafish

Journal of the American Society of Nephrology

Volumn 25, Issue 10, 2014, Pages 2222-2230

  Sussman, Caroline R ^a   Ward, Christopher J ^a   Leightner, Amanda C ^a   Smith, Jordan L ^a   Agarwal, Reema ^a   Harris, Peter C ^a   Torres, Vicente E ^a  

^a Mayo Clinic College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; MORPHOLINO OLIGONUCLEOTIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE IA; POLYCYSTIN 2; RNA; UNCLASSIFIED DRUG; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYSTOGENESIS; EMBRYO; EUKARYOTIC FLAGELLUM; EXON; HYDROCEPHALUS; KIDNEY CYST; KIDNEY DEVELOPMENT; NONHUMAN; OOCYTE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; STOP CODON; ZEBRA FISH; AMINO ACID SEQUENCE; ANIMAL; ANIMAL EMBRYO; DISEASE MODEL; EMBRYOLOGY; ENZYMOLOGY; HUMAN; KIDNEY; METABOLISM; MOLECULAR GENETICS; POLYCYSTIC KIDNEY DISEASES;

AMINO ACID SEQUENCE; ANIMALS; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 1; DISEASE MODELS, ANIMAL; EMBRYO, NONMAMMALIAN; HUMANS; HYDROCEPHALUS; KIDNEY; MOLECULAR SEQUENCE DATA; PHENOTYPE; POLYCYSTIC KIDNEY DISEASES; TRPP CATION CHANNELS; ZEBRAFISH;

EID: 84921753571     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013040421     Document Type: Article

References (31)

1. Harris PC, Torres VE: Polycystic kidney disease. Annu Rev Med 60: 321-337, 2009
2. Torres VE, Chapman AB, Devuyst O, Gansevoort RT, Grantham JJ, Higashihara E, Perrone RD, Krasa HB, Ouyang J, Czerwiec FS; TEMPO 3:4 Trial Investigators: Tolvaptan in patients with autosomal dominant polycystic kidney disease. N Engl J Med 367: 2407-2418, 2012
3. Torres VE, Harris PC, Pirson Y: Autosomal dominant polycystic kidney disease. Lancet 369: 1287-1301, 2007
4. Grantham JJ: Clinical practice. Autosomal dominant polycystic kidney disease. N Engl J Med 359: 1477-1485, 2008
5. Rees S, Kittikulsuth W, Roos K, Strait KA, Van Hoek A, Kohan DE: Adenylyl cyclase 6 de ficiency ameliorates polycystic kidney disease. J Am Soc Nephrol 25: 232-237, 2014
6. Torres VE, Harris PC: Autosomal dominant polycystic kidney disease: The last 3 years. Kidney Int 76: 149-168, 2009
7. Gattone VH 2nd, Wang X, Harris PC, Torres VE: Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist. Nat Med 9: 1323-1326, 2003
8. Torres VE, Wang X, Qian Q, Somlo S, Harris PC, Gattone VH 2nd: Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease. Nat Med 10: 363-364, 2004
9. Wang X, Gattone V 2nd, Harris PC, Torres VE: Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCKrat. J Am Soc Nephrol 16: 846-851, 2005
10. Lugnier C: Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents. Pharmacol Ther 109: 366-398, 2006
11. Bender AT, Beavo JA: Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use. Pharmacol Rev 58: 488-520, 2006
12. Conti M, Beavo J: Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling. Annu Rev Biochem 76: 481-511, 2007
13. Wang X, Ward CJ, Harris PC, Torres VE: Cyclic nucleotide signaling in polycystic kidney disease. Kidney Int 77: 129-140, 2010
14. Mangos S, Lam PY, Zhao A, Liu Y, Mudumana S, Vasilyev A, Liu A, Drummond IA: The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. Dis Model Mech 3: 354-365, 2010
15. Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker AG, Olale F, Schier AF, Drummond IA: Polycystin-2 immunolocalization and function in zebrafish. J Am Soc Nephrol 17: 2706-2718, 2006
16. Bisgrove BW, Snarr BS, Emrazian A, Yost HJ: Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebra fish left-right axis. Dev Biol 287: 274-288, 2005
17. Schottenfeld J, Sullivan-Brown J, Burdine RD: Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development 134: 1605-1615, 2007
18. Sun Z, Amsterdam A, Pazour GJ, Cole DG, Miller MS, Hopkins N: A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development 131: 4085-4093, 2004
19. Banales JM, Masyuk TV, Gradilone SA, Masyuk AI, Medina JF, LaRusso NF: The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD). Hepatology 49: 160-174, 2009
20. Rothschild SC, Francescatto L, Drummond IA, Tombes RM: CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia. Development 138: 3387-3397, 2011
21. Magenheimer BS, St John PL, Isom KS, Abrahamson DR, De Lisle RC, Wallace DP, Maser RL, Grantham JJ, Calvet JP: Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation. J Am Soc Nephrol 17: 3424-3437, 2006
22. Mahajan N, Kaur T, Puri V, Singla SK, Jha V, Puri S: Calciumameliorates renal cyst growth inmetanephric organ culture: A morphological study. J Environ Pathol Toxicol Oncol 31: 285-293, 2012
23. Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK: A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development. Dev Biol 364: 11-21, 2012
24. Perez-Aso M, Fernandez P, Mediero A, Chan ES, Cronstein BN: Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3. Faseb J 28: 802-812, 2013
25. Fogelgren B, Lin SY, Zuo X, Jaffe KM, Park KM, Reichert RJ, Bell PD, Burdine RD, Lipschutz JH: The exocyst protein Sec10 interactswith Polycystin-2 and knockdown causes PKD-phenotypes. PLoS Genet 7: e1001361, 2011
26. Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, Baehr W, Lyonnet S, Munnich A, Burglen L, Chassaing N, Encha-Ravazi F, Vekemans M, Gleeson JG, Valente EM, Jackson PK, Drummond IA, Saunier S, Attie-Bitach T: A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Hum Mutat 35: 137-146, 2014
27. Westerfield M: The Zebrafish Book, Eugene, OR, University of Oregon Press, 2000
28. McCurley AT, Callard GV: Characterization of housekeeping genes in zebra fish: Male-female differences and effects of tissue type, developmental stage and chemical treatment. BMCMol Biol 9: 102, 2008
29. Li C, Wen A, Shen B, Lu J, Huang Y, Chang Y: FastCloning: A highly simplified, puri fication-free, sequence- and ligation-independent PCR cloning method. BMC Biotechnol 11: 92, 2011
30. Sussman CR, Zhao J, Plata C, Lu J, Daly C, Angle N, DiPiero J, Drummond IA, Liang JO, Boron WF, Romero MF, Chang MH: Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish. Am J Physiol Cell Physiol 297: C865-C875, 2009
31. Sullivan-Brown J, Bisher ME, Burdine RD: Embedding, serial sectioning and staining of zebrafish embryos using JB-4 resin. Nat Protoc 6: 46-55, 2011