-
1
-
-
33845513010
-
Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis
-
Anderson, C., Bartlett, S. J., Gansner, J. M., Wilson, D., He, L., Gitlin, J. D., Kelsh, R. N. and Dowden, J. (2007). Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis. Mol. Biosyst. 3, 51-59.
-
(2007)
Mol. Biosyst.
, vol.3
, pp. 51-59
-
-
Anderson, C.1
Bartlett, S.J.2
Gansner, J.M.3
Wilson, D.4
He, L.5
Gitlin, J.D.6
Kelsh, R.N.7
Dowden, J.8
-
2
-
-
34547507517
-
Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2
-
Anyatonwu, G. I., Estrada, M., Tian, X., Somlo, S. and Ehrlich, B. E. (2007). Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. Proc. Natl. Acad. Sci. USA 104, 6454-6459.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6454-6459
-
-
Anyatonwu, G.I.1
Estrada, M.2
Tian, X.3
Somlo, S.4
Ehrlich, B.E.5
-
3
-
-
28444497446
-
Integrin structure, allostery, and bidirectional signaling
-
Arnaout, M. A., Mahalingam, B. and Xiong, J. P. (2005). Integrin structure, allostery, and bidirectional signaling. Annu. Rev. Cell Dev. Biol. 21, 381-410.
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 381-410
-
-
Arnaout, M.A.1
Mahalingam, B.2
Xiong, J.P.3
-
4
-
-
27744436054
-
Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis
-
Bisgrove, B. W., Snarr, B. S., Emrazian, A. and Yost, H. J. (2005). Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev. Biol. 287, 274-288.
-
(2005)
Dev. Biol.
, vol.287
, pp. 274-288
-
-
Bisgrove, B.W.1
Snarr, B.S.2
Emrazian, A.3
Yost, H.J.4
-
5
-
-
21244468364
-
A mechanistic approach to inherited polycystic kidney disease
-
Bissler, J. J. and Dixon, B. P. (2005). A mechanistic approach to inherited polycystic kidney disease. Pediatr. Nephrol. 20, 558-566.
-
(2005)
Pediatr. Nephrol.
, vol.20
, pp. 558-566
-
-
Bissler, J.J.1
Dixon, B.P.2
-
6
-
-
34948834648
-
Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion
-
Boca, M., D'Amato, L., Distefano, G., Polishchuk, R. S., Germino, G. G. and Boletta, A. (2007). Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion. Mol. Biol. Cell 18, 4050-4061.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4050-4061
-
-
Boca, M.1
D'Amato, L.2
Distefano, G.3
Polishchuk, R.S.4
Germino, G.G.5
Boletta, A.6
-
7
-
-
0035834136
-
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
-
Boulter, C., Mulroy, S., Webb, S., Fleming, S., Brindle, K. and Sandford, R. (2001). Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene. Proc. Natl. Acad. Sci. USA 98, 12174-12179.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12174-12179
-
-
Boulter, C.1
Mulroy, S.2
Webb, S.3
Fleming, S.4
Brindle, K.5
Sandford, R.6
-
8
-
-
0037213012
-
Extracellular matrix in vascular morphogenesis and disease: Structure versus signal
-
Brooke, B. S., Karnik, S. K. and Li, D. Y. (2003). Extracellular matrix in vascular morphogenesis and disease: structure versus signal. Trends Cell. Biol. 13, 51-56.
-
(2003)
Trends Cell. Biol.
, vol.13
, pp. 51-56
-
-
Brooke, B.S.1
Karnik, S.K.2
Li, D.Y.3
-
9
-
-
0035083551
-
The genetics and physiology of polycystic kidney disease
-
Calvet, J. P. and Grantham, J. J. (2001). The genetics and physiology of polycystic kidney disease. Semin. Nephrol. 21, 107-123.
-
(2001)
Semin. Nephrol.
, vol.21
, pp. 107-123
-
-
Calvet, J.P.1
Grantham, J.J.2
-
10
-
-
0027102902
-
Extracellular matrix formation by epithelial cells from human polycystic kidney cysts in culture
-
Candiano, G., Gusmano, R., Altieri, P., Bertelli, R., Ginevri, F., Coviello, D. A., Sessa, A., Caridi, G. and Ghiggeri, G. M. (1992). Extracellular matrix formation by epithelial cells from human polycystic kidney cysts in culture. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 63, 1-9.
-
(1992)
Virchows Arch. B Cell Pathol. Incl. Mol. Pathol.
, vol.63
, pp. 1-9
-
-
Candiano, G.1
Gusmano, R.2
Altieri, P.3
Bertelli, R.4
Ginevri, F.5
Coviello, D.A.6
Sessa, A.7
Caridi, G.8
Ghiggeri, G.M.9
-
11
-
-
0018820721
-
Ultrastructure and function of cysts from human adult polycystic kidneys
-
Cuppage, F. E., Huseman, R. A., Chapman, A. and Grantham, J. J. (1980). Ultrastructure and function of cysts from human adult polycystic kidneys. Kidney Int. 17, 372-381. (Pubitemid 10101596)
-
(1980)
Kidney International
, vol.17
, Issue.3
, pp. 372-381
-
-
Cuppage, F.E.1
Huseman, R.A.2
Chapman, A.3
Grantham, J.J.4
-
12
-
-
0032446549
-
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
-
Drummond, I. A., Majumdar, A., Hentschel, H., Elger, M., Solnica-Krezel, L., Schier, A. F., Neuhauss, S. C., Stemple, D. L., Zwartkruis, F., Rangini, Z. et al. (1998). Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development 125, 4655-4667. (Pubitemid 29027196)
-
(1998)
Development
, vol.125
, Issue.23
, pp. 4655-4667
-
-
Drummond, I.A.1
Majumdar, A.2
Hentschel, H.3
Elger, M.4
Solnica-Krezel, L.5
Schier, A.F.6
Neuhauss, S.C.F.7
Stemple, D.L.8
Zwartkruis, F.9
Rangini, Z.10
Driever, W.11
Fishman, M.C.12
-
13
-
-
0035887293
-
Visualizing normal and defective bone development in zebrafish embryos using the fluorescent chromophore calcein
-
Du, S. J., Frenkel, V., Kindschi, G. and Zohar, Y. (2001). Visualizing normal and defective bone development in zebrafish embryos using the fluorescent chromophore calcein. Dev. Biol. 238, 239-246.
-
(2001)
Dev. Biol.
, vol.238
, pp. 239-246
-
-
Du, S.J.1
Frenkel, V.2
Kindschi, G.3
Zohar, Y.4
-
14
-
-
0023924440
-
Altered mRNA expression of basement membrane components in a murine model of polycystic kidney disease
-
Ebihara, I., Killen, P. D., Laurie, G. W., Huang, T., Yamada, Y., Martin, G. R. and Brown, K. S. (1988). Altered mRNA expression of basement membrane components in a murine model of polycystic kidney disease. Lab. Invest. 58, 262-269.
-
(1988)
Lab. Invest.
, vol.58
, pp. 262-269
-
-
Ebihara, I.1
Killen, P.D.2
Laurie, G.W.3
Huang, T.4
Yamada, Y.5
Martin, G.R.6
Brown, K.S.7
-
15
-
-
0028935398
-
Altered extracellular matrix component gene expression in murine polycystic kidney
-
Ebihara, I., Nakamura, T., Takahashi, T., Yamamoto, M., Tomino, Y., Nagao, S., Takahashi, H. and Koide, H. (1995). Altered extracellular matrix component gene expression in murine polycystic kidney. Renal Physiol. Biochem. 18, 73-80.
-
(1995)
Renal Physiol. Biochem.
, vol.18
, pp. 73-80
-
-
Ebihara, I.1
Nakamura, T.2
Takahashi, T.3
Yamamoto, M.4
Tomino, Y.5
Nagao, S.6
Takahashi, H.7
Koide, H.8
-
16
-
-
0031955518
-
Base-calling of automated sequencer traces using phred. I. Accuracy assessment
-
Ewing, B., Hillier, L., Wendl, M. C. and Green, P. (1998). Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8, 175-185.
-
(1998)
Genome Res.
, vol.8
, pp. 175-185
-
-
Ewing, B.1
Hillier, L.2
Wendl, M.C.3
Green, P.4
-
17
-
-
48149114326
-
The subcellular localization of TRPP2 modulates its function
-
Fu, X., Wang, Y., Schetle, N., Gao, H., Putz, M., von Gersdorff, G., Walz, G. and Kramer-Zucker, A. G. (2008). The subcellular localization of TRPP2 modulates its function. J. Am. Soc. Nephrol. 19, 1342-1351.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1342-1351
-
-
Fu, X.1
Wang, Y.2
Schetle, N.3
Gao, H.4
Putz, M.5
Von Gersdorff, G.6
Walz, G.7
Kramer-Zucker, A.G.8
-
18
-
-
34347241358
-
Essential role of lysyl oxidases in notochord development
-
Gansner, J. M., Mendelsohn, B. A., Hultman, K. A., Johnson, S. L. and Gitlin, J. D. (2007). Essential role of lysyl oxidases in notochord development. Dev. Biol. 307, 202-213.
-
(2007)
Dev. Biol.
, vol.307
, pp. 202-213
-
-
Gansner, J.M.1
Mendelsohn, B.A.2
Hultman, K.A.3
Johnson, S.L.4
Gitlin, J.D.5
-
19
-
-
33645889655
-
Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways
-
Giannone, G. and Sheetz, M. P. (2006). Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. Trends Cell Biol. 16, 213-223.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 213-223
-
-
Giannone, G.1
Sheetz, M.P.2
-
20
-
-
0141703576
-
Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells
-
Grimm, D. H., Cai, Y., Chauvet, V., Rajendran, V., Zeltner, R., Geng, L., Avner, E. D., Sweeney, W., Somlo, S. and Caplan, M. J. (2003). Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J. Biol. Chem. 278, 36786-36793.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36786-36793
-
-
Grimm, D.H.1
Cai, Y.2
Chauvet, V.3
Rajendran, V.4
Zeltner, R.5
Geng, L.6
Avner, E.D.7
Sweeney, W.8
Somlo, S.9
Caplan, M.J.10
-
21
-
-
0034700483
-
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
-
DOI 10.1038/35050128
-
Hanaoka, K., Qian, F., Boletta, A., Bhunia, A. K., Piontek, K., Tsiokas, L., Sukhatme, V. P., Guggino, W. B. and Germino, G. G. (2000). Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature 408, 990-994. (Pubitemid 32101647)
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 990-994
-
-
Hanaoka, K.1
Qian, F.2
Boletta, A.3
Bhunia, A.K.4
Piontek, K.5
Tsiokas, L.6
Sukhatme, V.P.7
Guggino, W.B.8
Germino, G.G.9
-
22
-
-
0142141199
-
Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility
-
Hanks, S. K., Ryzhova, L., Shin, N. Y. and Brabek, J. (2003). Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility. Front. Biosci. 8, d982-d996.
-
(2003)
Front. Biosci.
, vol.8
-
-
Hanks, S.K.1
Ryzhova, L.2
Shin, N.Y.3
Brabek, J.4
-
23
-
-
35148840431
-
Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model
-
Hassane, S., Claij, N., Lantinga-van Leeuwen, I. S., Van Munsteren, J. C., Van Lent, N., Hanemaaijer, R., Breuning, M. H., Peters, D. J. and DeRuiter, M. C. (2007). Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model. Arterioscler. Thromb. Vasc. Biol. 27, 2177-2183.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 2177-2183
-
-
Hassane, S.1
Claij, N.2
Lantinga-van Leeuwen, I.S.3
Van Munsteren, J.C.4
Van Lent, N.5
Hanemaaijer, R.6
Breuning, M.H.7
Peters, D.J.8
DeRuiter, M.C.9
-
24
-
-
0023899090
-
Basement membrane gene expression in polycystic kidney disease
-
Haverty, T. P. and Neilson, E. G. (1988). Basement membrane gene expression in polycystic kidney disease. Lab. Invest. 58, 245-248.
-
(1988)
Lab. Invest.
, vol.58
, pp. 245-248
-
-
Haverty, T.P.1
Neilson, E.G.2
-
25
-
-
23944484197
-
Expression of polycystin-1 enhances endoplasmic reticulum calcium uptake and decreases capacitative calcium entry in ATP-stimulated MDCK cells
-
Hooper, K. M., Boletta, A., Germino, G. G., Hu, Q., Ziegelstein, R. C. and Sutters, M. (2005). Expression of polycystin-1 enhances endoplasmic reticulum calcium uptake and decreases capacitative calcium entry in ATP-stimulated MDCK cells. Am. J. Physiol. Renal Physiol. 289, F521-F530.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Hooper, K.M.1
Boletta, A.2
Germino, G.G.3
Hu, Q.4
Ziegelstein, R.C.5
Sutters, M.6
-
26
-
-
0023786508
-
Echocardiographic findings in autosomal dominant polycystic kidney disease
-
Hossack, K. F., Leddy, C. L., Johnson, A. M., Schrier, R. W. and Gabow, P. A. (1988). Echocardiographic findings in autosomal dominant polycystic kidney disease. N. Engl. J. Med. 319, 907-912.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 907-912
-
-
Hossack, K.F.1
Leddy, C.L.2
Johnson, A.M.3
Schrier, R.W.4
Gabow, P.A.5
-
27
-
-
0029069583
-
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
-
Hughes, J., Ward, C. J., Peral, B., Aspinwall, R., Clark, K., San Millan, J. L., Gamble, V. and Harris, P. C. (1995). The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains. Nat. Genet. 10, 151-160.
-
(1995)
Nat. Genet.
, vol.10
, pp. 151-160
-
-
Hughes, J.1
Ward, C.J.2
Peral, B.3
Aspinwall, R.4
Clark, K.5
San Millan, J.L.6
Gamble, V.7
Harris, P.C.8
-
28
-
-
0142244215
-
Beta4 integrin and laminin 5 are aberrantly expressed in polycystic kidney disease: Role in increased cell adhesion and migration
-
Joly, D., Morel, V., Hummel, A., Ruello, A., Nusbaum, P., Patey, N., Noel, L. H., Rousselle, P. and Knebelmann, B. (2003). Beta4 integrin and laminin 5 are aberrantly expressed in polycystic kidney disease: role in increased cell adhesion and migration. Am. J. Pathol. 163, 1791-1800.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 1791-1800
-
-
Joly, D.1
Morel, V.2
Hummel, A.3
Ruello, A.4
Nusbaum, P.5
Patey, N.6
Noel, L.H.7
Rousselle, P.8
Knebelmann, B.9
-
29
-
-
33748748479
-
The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells
-
Joly, D., Ishibe, S., Nickel, C., Yu, Z., Somlo, S. and Cantley, L. G. (2006). The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells. J. Biol. Chem. 281, 26329-26339.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26329-26339
-
-
Joly, D.1
Ishibe, S.2
Nickel, C.3
Yu, Z.4
Somlo, S.5
Cantley, L.G.6
-
30
-
-
0031042188
-
Cystic kidneys associated with connective tissue disorders
-
Kaplan, B. S., Kaplan, P. and Kessler, A. (1997). Cystic kidneys associated with connective tissue disorders. Am. J. Med. Genet. 69, 133-137.
-
(1997)
Am. J. Med. Genet.
, vol.69
, pp. 133-137
-
-
Kaplan, B.S.1
Kaplan, P.2
Kessler, A.3
-
31
-
-
0034903044
-
A morpholino phenocopy of the cyclops mutation
-
Karlen, S. and Rebagliati, M. (2001). A morpholino phenocopy of the cyclops mutation. Genesis 30, 126-128.
-
(2001)
Genesis
, vol.30
, pp. 126-128
-
-
Karlen, S.1
Rebagliati, M.2
-
32
-
-
0034652247
-
Polycystin 1 is required for the structural integrity of blood vessels
-
Kim, K., Drummond, I., Ibraghimov-Beskrovnaya, O., Klinger, K. and Arnaout, M. A. (2000). Polycystin 1 is required for the structural integrity of blood vessels. Proc. Natl. Acad. Sci. USA 97, 1731-1736.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1731-1736
-
-
Kim, K.1
Drummond, I.2
Ibraghimov-Beskrovnaya, O.3
Klinger, K.4
Arnaout, M.A.5
-
33
-
-
0037384993
-
Endothelin 1-mediated regulation of pharyngeal bone development in zebrafish
-
DOI 10.1242/dev.00338
-
Kimmel, C. B., Ullmann, B., Walker, M., Miller, C. T. and Crump, J. G. (2003). Endothelin 1-mediated regulation of pharyngeal bone development in zebrafish. Development 130, 1339-1351. (Pubitemid 36410782)
-
(2003)
Development
, vol.130
, Issue.7
, pp. 1339-1351
-
-
Kimmel, C.B.1
Ullmann, B.2
Walker, M.3
Miller, C.T.4
Crump, J.G.5
-
34
-
-
48149104228
-
Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes
-
Kolpakova-Hart, E., Nicolae, C., Zhou, J. and Olsen, B. R. (2008). Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes. Matrix Biol. 27, 505-512.
-
(2008)
Matrix Biol.
, vol.27
, pp. 505-512
-
-
Kolpakova-Hart, E.1
Nicolae, C.2
Zhou, J.3
Olsen, B.R.4
-
35
-
-
0036122434
-
Polycystin-2 is an intracellular calcium release channel
-
Koulen, P., Cai, Y., Geng, L., Maeda, Y., Nishimura, S., Witzgall, R., Ehrlich, B. E. and Somlo, S. (2002). Polycystin-2 is an intracellular calcium release channel. Nat. Cell Biol. 4, 191-197.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 191-197
-
-
Koulen, P.1
Cai, Y.2
Geng, L.3
Maeda, Y.4
Nishimura, S.5
Witzgall, R.6
Ehrlich, B.E.7
Somlo, S.8
-
36
-
-
19944406428
-
Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease
-
Lantinga-van Leeuwen, I. S., Dauwerse, J. G., Baelde, H. J., Leonhard, W. N., van de Wal, A., Ward, C. J., Verbeek, S., Deruiter, M. C., Breuning, M. H., de Heer, E. et al. (2004). Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease. Hum. Mol. Genet. 13, 3069-3077.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 3069-3077
-
-
Lantinga-van Leeuwen, I.S.1
Dauwerse, J.G.2
Baelde, H.J.3
Leonhard, W.N.4
Van De Wal, A.5
Ward, C.J.6
Verbeek, S.7
Deruiter, M.C.8
Breuning, M.H.9
De Heer, E.10
-
37
-
-
0037884961
-
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
-
Lin, F., Hiesberger, T., Cordes, K., Sinclair, A. M., Goldstein, L. S., Somlo, S. and Igarashi, P. (2003). Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc. Natl. Acad. Sci. USA 100, 5286-5291.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5286-5291
-
-
Lin, F.1
Hiesberger, T.2
Cordes, K.3
Sinclair, A.M.4
Goldstein, L.S.5
Somlo, S.6
Igarashi, P.7
-
38
-
-
0035504102
-
Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
-
Lu, W., Shen, X., Pavlova, A., Lakkis, M., Ward, C. J., Pritchard, L., Harris, P. C., Genest, D. R., Perez-Atayde, A. R. and Zhou, J. (2001). Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects. Hum. Mol. Genet. 10, 2385-2396.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2385-2396
-
-
Lu, W.1
Shen, X.2
Pavlova, A.3
Lakkis, M.4
Ward, C.J.5
Pritchard, L.6
Harris, P.C.7
Genest, D.R.8
Perez-Atayde, A.R.9
Zhou, J.10
-
39
-
-
15844385078
-
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
-
Mochizuki, T., Wu, G., Hayashi, T., Xenophontos, S. L., Veldhuisen, B., Saris, J. J., Reynolds, D. M., Cai, Y., Gabow, P. A., Pierides, A. et al. (1996). PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272, 1339-1342. (Pubitemid 26199975)
-
(1996)
Science
, vol.272
, Issue.5266
, pp. 1339-1342
-
-
Mochizuki, T.1
Wu, G.2
Hayashi, T.3
Xenophontos, S.L.4
Veldhuisen, B.5
Saris, J.J.6
Reynolds, D.M.7
Cai, Y.8
Gabow, P.A.9
Pierides, A.10
Kimberling, W.J.11
Breuning, M.H.12
Deltas, C.C.13
Peters, D.J.M.14
Somlo, S.15
-
40
-
-
0030929882
-
Abdominal wall hernia in autosomal dominant polycystic kidney disease
-
Morris-Stiff, G., Coles, G., Moore, R., Jurewicz, A. and Lord, R. (1997). Abdominal wall hernia in autosomal dominant polycystic kidney disease. Br. J. Surg. 84, 615-617.
-
(1997)
Br. J. Surg.
, vol.84
, pp. 615-617
-
-
Morris-Stiff, G.1
Coles, G.2
Moore, R.3
Jurewicz, A.4
Lord, R.5
-
41
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli, S. M., Alenghat, F. J., Luo, Y., Williams, E., Vassilev, P., Li, X., Elia, A. E., Lu, W., Brown, E. M., Quinn, S. J. et al. (2003). Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33, 129-137.
-
(2003)
Nat. Genet.
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
Elia, A.E.7
Lu, W.8
Brown, E.M.9
Quinn, S.J.10
-
42
-
-
33749268369
-
Polycystin-2 immunolocalization and function in zebrafish
-
Obara, T., Mangos, S., Liu, Y., Zhao, J., Wiessner, S., Kramer-Zucker, A. G., Olale, F., Schier, A. F. and Drummond, I. A. (2006). Polycystin-2 immunolocalization and function in zebrafish. J. Am. Soc. Nephrol. 17, 2706-2718.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2706-2718
-
-
Obara, T.1
Mangos, S.2
Liu, Y.3
Zhao, J.4
Wiessner, S.5
Kramer-Zucker, A.G.6
Olale, F.7
Schier, A.F.8
Drummond, I.A.9
-
43
-
-
36849037019
-
A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
-
Piontek, K., Menezes, L. F., Garcia-Gonzalez, M. A., Huso, D. L. and Germino, G. G. (2007). A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1. Nat. Med. 13, 1490-1495.
-
(2007)
Nat. Med.
, vol.13
, pp. 1490-1495
-
-
Piontek, K.1
Menezes, L.F.2
Garcia-Gonzalez, M.A.3
Huso, D.L.4
Germino, G.G.5
-
44
-
-
0034326865
-
A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype
-
Pritchard, L., Sloane-Stanley, J. A., Sharpe, J. A., Aspinwall, R., Lu, W., Buckle, V., Strmecki, L., Walker, D., Ward, C. J., Alpers, C. E. et al. (2000). A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype. Hum. Mol. Genet. 9, 2617-2627.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2617-2627
-
-
Pritchard, L.1
Sloane-Stanley, J.A.2
Sharpe, J.A.3
Aspinwall, R.4
Lu, W.5
Buckle, V.6
Strmecki, L.7
Walker, D.8
Ward, C.J.9
Alpers, C.E.10
-
45
-
-
0030909957
-
PKD1 interacts with PKD2 through a probable coiled-coil domain
-
Qian, F., Germino, F. J., Cai, Y., Zhang, X., Somlo, S. and Germino, G. G. (1997). PKD1 interacts with PKD2 through a probable coiled-coil domain. Nat. Genet. 16, 179-183.
-
(1997)
Nat. Genet.
, vol.16
, pp. 179-183
-
-
Qian, F.1
Germino, F.J.2
Cai, Y.3
Zhang, X.4
Somlo, S.5
Germino, G.G.6
-
46
-
-
0041677595
-
Analysis of the polycystins in aortic vascular smooth muscle cells
-
Qian, Q., Li, M., Cai, Y., Ward, C. J., Somlo, S., Harris, P. C. and Torres, V. E. (2003a). Analysis of the polycystins in aortic vascular smooth muscle cells. J. Am. Soc. Nephrol. 14, 2280-2287.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2280-2287
-
-
Qian, Q.1
Li, M.2
Cai, Y.3
Ward, C.J.4
Somlo, S.5
Harris, P.C.6
Torres, V.E.7
-
47
-
-
0043133391
-
Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells
-
Qian, Q., Hunter, L. W., Li, M., Marin-Padilla, M., Prakash, Y. S., Somlo, S., Harris, P. C., Torres, V. E. and Sieck, G. C. (2003b). Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. Hum. Mol. Genet. 12, 1875-1880.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1875-1880
-
-
Qian, Q.1
Hunter, L.W.2
Li, M.3
Marin-Padilla, M.4
Prakash, Y.S.5
Somlo, S.6
Harris, P.C.7
Torres, V.E.8
Sieck, G.C.9
-
48
-
-
38449114631
-
Increased occurrence of pericardial effusion in patients with autosomal dominant polycystic kidney disease
-
Qian, Q., Hartman, R. P., King, B. F. and Torres, V. E. (2007). Increased occurrence of pericardial effusion in patients with autosomal dominant polycystic kidney disease. Clin. J. Am. Soc. Nephrol. 2, 1223-1227.
-
(2007)
Clin. J. Am. Soc. Nephrol.
, vol.2
, pp. 1223-1227
-
-
Qian, Q.1
Hartman, R.P.2
King, B.F.3
Torres, V.E.4
-
49
-
-
33646521976
-
Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism
-
Riera, M., Burtey, S. and Fontes, M. (2006). Transcriptome analysis of a rat PKD model: Importance of genes involved in extracellular matrix metabolism. Kidney Int. 69, 1558-1563.
-
(2006)
Kidney Int.
, vol.69
, pp. 1558-1563
-
-
Riera, M.1
Burtey, S.2
Fontes, M.3
-
50
-
-
13944264013
-
Genetics of intracranial aneurysms
-
Ruigrok, Y. M., Rinkel, G. J. and Wijmenga, C. (2005). Genetics of intracranial aneurysms. Lancet Neurol. 4, 179-189.
-
(2005)
Lancet Neurol.
, vol.4
, pp. 179-189
-
-
Ruigrok, Y.M.1
Rinkel, G.J.2
Wijmenga, C.3
-
51
-
-
0028293767
-
Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease
-
Schafer, K., Bader, M., Gretz, N., Oberbaumer, I. and Bachmann, S. (1994). Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease. Exp. Nephrol. 2, 190-195.
-
(1994)
Exp. Nephrol.
, vol.2
, pp. 190-195
-
-
Schafer, K.1
Bader, M.2
Gretz, N.3
Oberbaumer, I.4
Bachmann, S.5
-
52
-
-
0034326319
-
Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells
-
Scheffers, M. S., van der Bent, P., Prins, F., Spruit, L., Breuning, M. H., Litvinov, S. V., de Heer, E. and Peters, D. J. (2000). Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells. Hum. Mol. Genet. 9, 2743-2750.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2743-2750
-
-
Scheffers, M.S.1
Van Der Bent, P.2
Prins, F.3
Spruit, L.4
Breuning, M.H.5
Litvinov, S.V.6
De Heer, E.7
Peters, D.J.8
-
53
-
-
34248597580
-
Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw
-
DOI 10.1242/dev.02827
-
Schottenfeld, J., Sullivan-Brown, J. and Burdine, R. D. (2007). Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development 134, 1605-1615. (Pubitemid 46746312)
-
(2007)
Development
, vol.134
, Issue.8
, pp. 1605-1615
-
-
Schottenfeld, J.1
Sullivan-Brown, J.2
Burdine, R.D.3
-
54
-
-
15544375977
-
Zebrafish notochordal basement membrane: Signaling and structure
-
Scott, A. and Stemple, D. L. (2005). Zebrafish notochordal basement membrane: signaling and structure. Curr. Top. Dev. Biol. 65, 229-253.
-
(2005)
Curr. Top. Dev. Biol.
, vol.65
, pp. 229-253
-
-
Scott, A.1
Stemple, D.L.2
-
55
-
-
33745866295
-
A hypomorphic mutation in the mouse laminin alpha5 gene causes polycystic kidney disease
-
Shannon, M. B., Patton, B. L., Harvey, S. J. and Miner, J. H. (2006). A hypomorphic mutation in the mouse laminin alpha5 gene causes polycystic kidney disease. J. Am. Soc. Nephrol. 17, 1913-1922.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1913-1922
-
-
Shannon, M.B.1
Patton, B.L.2
Harvey, S.J.3
Miner, J.H.4
-
56
-
-
44349088262
-
Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1
-
Shibazaki, S., Yu, Z., Nishio, S., Tian, X., Thomson, R. B., Mitobe, M., Louvi, A., Velazquez, H., Ishibe, S., Cantley, L. G. et al. (2008). Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1. Hum. Mol. Genet. 17, 1505-1516.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1505-1516
-
-
Shibazaki, S.1
Yu, Z.2
Nishio, S.3
Tian, X.4
Thomson, R.B.5
Mitobe, M.6
Louvi, A.7
Velazquez, H.8
Ishibe, S.9
Cantley, L.G.10
-
57
-
-
0027721286
-
A kindred exhibiting cosegregation of an overlap connective tissue disorder and the chromosome 16 linked form of autosomal dominant polycystic kidney disease
-
Somlo, S., Rutecki, G., Giuffra, L. A., Reeders, S. T., Cugino, A. and Whittier, F. C. (1993). A kindred exhibiting cosegregation of an overlap connective tissue disorder and the chromosome 16 linked form of autosomal dominant polycystic kidney disease. J. Am. Soc. Nephrol. 4, 1371-1378.
-
(1993)
J. Am. Soc. Nephrol.
, vol.4
, pp. 1371-1378
-
-
Somlo, S.1
Rutecki, G.2
Giuffra, L.A.3
Reeders, S.T.4
Cugino, A.5
Whittier, F.C.6
-
58
-
-
39149144464
-
Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants
-
Sullivan-Brown, J., Schottenfeld, J., Okabe, N., Hostetter, C. L., Serluca, F. C., Thiberge, S. Y. and Burdine, R. D. (2008). Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Dev. Biol. 314, 261-275.
-
(2008)
Dev. Biol.
, vol.314
, pp. 261-275
-
-
Sullivan-Brown, J.1
Schottenfeld, J.2
Okabe, N.3
Hostetter, C.L.4
Serluca, F.C.5
Thiberge, S.Y.6
Burdine, R.D.7
-
59
-
-
4544383179
-
A genetic screen in zebrafish indentifies cilia genes as a principal cause of cystic kidney
-
DOI 10.1242/dev.01240
-
Sun, Z., Amsterdam, A., Pazour, G. J., Cole, D. G., Miller, M. S. and Hopkins, N. (2004). A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development 131, 4085-4093. (Pubitemid 39232166)
-
(2004)
Development
, vol.131
, Issue.16
, pp. 4085-4093
-
-
Sun, Z.1
Amsterdam, A.2
Pazour, G.J.3
Cole, D.G.4
Miller, M.S.5
Hopkins, N.6
-
60
-
-
0037320210
-
Autosomal dominant polycystic kidney disease: Molecular genetics and pathophysiology
-
Sutters, M. and Germino, G. G. (2003). Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology. J. Lab. Clin. Med. 141, 91-101.
-
(2003)
J. Lab. Clin. Med.
, vol.141
, pp. 91-101
-
-
Sutters, M.1
Germino, G.G.2
-
61
-
-
57149094707
-
Pkd1 inactivation induced in adulthood produces focal cystic disease
-
Takakura, A., Contrino, L., Beck, A. W. and Zhou, J. (2008). Pkd1 inactivation induced in adulthood produces focal cystic disease. J. Am. Soc. Nephrol. 19, 2351-2363.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 2351-2363
-
-
Takakura, A.1
Contrino, L.2
Beck, A.W.3
Zhou, J.4
-
62
-
-
0030979629
-
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2
-
Tsiokas, L., Kim, E., Arnould, T., Sukhatme, V. P. and Walz, G. (1997). Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. Proc. Natl. Acad. Sci. USA 94, 6965-6970.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6965-6970
-
-
Tsiokas, L.1
Kim, E.2
Arnould, T.3
Sukhatme, V.P.4
Walz, G.5
-
63
-
-
0029551130
-
Intracranial aneurysms in polycystic kidney disease linked to chromosome 4
-
van Dijk, M. A., Chang, P. C., Peters, D. J. and Breuning, M. H. (1995). Intracranial aneurysms in polycystic kidney disease linked to chromosome 4. J. Am. Soc. Nephrol. 6, 1670-1673.
-
(1995)
J. Am. Soc. Nephrol.
, vol.6
, pp. 1670-1673
-
-
Van Dijk, M.A.1
Chang, P.C.2
Peters, D.J.3
Breuning, M.H.4
-
64
-
-
57349096661
-
Periostin induces proliferation of human autosomal dominant polycystic kidney cells through alphaV-integrin receptor
-
Wallace, D. P., Quante, M. T., Reif, G. A., Nivens, E., Ahmed, F., Hempson, S. J., Blanco, G. and Yamaguchi, T. (2008). Periostin induces proliferation of human autosomal dominant polycystic kidney cells through alphaV-integrin receptor. Am. J. Physiol. Renal Physiol. 295, F1463-F1471.
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.295
-
-
Wallace, D.P.1
Quante, M.T.2
Reif, G.A.3
Nivens, E.4
Ahmed, F.5
Hempson, S.J.6
Blanco, G.7
Yamaguchi, T.8
-
65
-
-
48249091279
-
Heterologous expression of polycystin-1 inhibits endoplasmic reticulum calcium leak in stably transfected MDCK cells
-
Weber, K. H., Lee, E. K., Basavanna, U., Lindley, S., Ziegelstein, R. C., Germino, G. G. and Sutters, M. (2008). Heterologous expression of polycystin-1 inhibits endoplasmic reticulum calcium leak in stably transfected MDCK cells. Am. J. Physiol. Renal Physiol. 294, F1279-F1286.
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.294
-
-
Weber, K.H.1
Lee, E.K.2
Basavanna, U.3
Lindley, S.4
Ziegelstein, R.C.5
Germino, G.G.6
Sutters, M.7
-
67
-
-
0035978520
-
The polycystin-1 C-type lectin domain binds carbohydrate in a calcium-dependent manner, and interacts with extracellular matrix proteins in vitro
-
DOI 10.1016/S0925-4439(01)00046-1, PII S0925443901000461
-
Weston, B. S., Bagneris, C., Price, R. G. and Stirling, J. L. (2001). The polycystin-1 Ctype lectin domain binds carbohydrate in a calcium-dependent manner, and interacts with extracellular matrix proteins in vitro. Biochim. Biophys Acta 1536, 161-176. (Pubitemid 32530815)
-
(2001)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1536
, Issue.2-3
, pp. 161-176
-
-
Weston, B.S.1
Bagneris, C.2
Price, R.G.3
Stirling, J.L.4
-
68
-
-
0344085884
-
Cystic diseases of the kidney: Role of adhesion molecules in normal and abnormal tubulogenesis
-
Wilson, P. D. and Burrow, C. R. (1999). Cystic diseases of the kidney: role of adhesion molecules in normal and abnormal tubulogenesis. Exp. Nephrol. 7, 114-124.
-
(1999)
Exp. Nephrol.
, vol.7
, pp. 114-124
-
-
Wilson, P.D.1
Burrow, C.R.2
-
69
-
-
0026571382
-
Abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia
-
Wilson, P. D., Hreniuk, D. and Gabow, P. A. (1992). Abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia. J. Cell Physiol. 150, 360-369.
-
(1992)
J. Cell Physiol.
, vol.150
, pp. 360-369
-
-
Wilson, P.D.1
Hreniuk, D.2
Gabow, P.A.3
-
70
-
-
0032831465
-
The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia
-
Wilson, P. D., Geng, L., Li, X. and Burrow, C. R. (1999). The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia. Lab. Invest. 79, 1311-1323.
-
(1999)
Lab. Invest.
, vol.79
, pp. 1311-1323
-
-
Wilson, P.D.1
Geng, L.2
Li, X.3
Burrow, C.R.4
-
71
-
-
3042799330
-
Focal adhesion regulation of cell behavior
-
Wozniak, M. A., Modzelewska, K., Kwong, L. and Keely, P. J. (2004). Focal adhesion regulation of cell behavior. Biochim. Biophys. Acta. 1692, 103-119.
-
(2004)
Biochim. Biophys. Acta.
, vol.1692
, pp. 103-119
-
-
Wozniak, M.A.1
Modzelewska, K.2
Kwong, L.3
Keely, P.J.4
-
72
-
-
0036667984
-
Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease
-
Wu, G., Tian, X., Nishimura, S., Markowitz, G. S., D'Agati, V., Park, J. H., Yao, L., Li, L., Geng, L., Zhao, H. et al. (2002). Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Hum. Mol. Genet. 11, 1845-1854.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1845-1854
-
-
Wu, G.1
Tian, X.2
Nishimura, S.3
Markowitz, G.S.4
D'Agati, V.5
Park, J.H.6
Yao, L.7
Li, L.8
Geng, L.9
Zhao, H.10
-
73
-
-
33847792873
-
Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling
-
Xu, C., Rossetti, S., Jiang, L., Harris, P. C., Brown-Glaberman, U., Wandinger-Ness, A., Bacallao, R. and Alper, S. L. (2007). Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling. Am. J. Physiol. Renal. Physiol. 292, F930-F945.
-
(2007)
Am. J. Physiol. Renal. Physiol.
, vol.292
-
-
Xu, C.1
Rossetti, S.2
Jiang, L.3
Harris, P.C.4
Brown-Glaberman, U.5
Wandinger-Ness, A.6
Bacallao, R.7
Alper, S.L.8
-
74
-
-
0035824508
-
Polycystin-1 interacts with intermediate filaments
-
Xu, G. M., Sikaneta, T., Sullivan, B. M., Zhang, Q., Andreucci, M., Stehle, T., Drummond, I. and Arnaout, M. A. (2001). Polycystin-1 interacts with intermediate filaments. J. Biol. Chem. 276, 46544-46552.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46544-46552
-
-
Xu, G.M.1
Sikaneta, T.2
Sullivan, B.M.3
Zhang, Q.4
Andreucci, M.5
Stehle, T.6
Drummond, I.7
Arnaout, M.A.8
-
75
-
-
0036785149
-
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
-
Yoder, B. K., Hou, X. and Guay-Woodford, L. M. (2002). The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J. Am. Soc. Nephrol. 13, 2508-2516.
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2508-2516
-
-
Yoder, B.K.1
Hou, X.2
Guay-Woodford, L.M.3
|