Division of Labor with a workforce of one: Challenges in specifying effector and memory T cell fate

Science

Volumn 317, Issue 5838, 2007, Pages 622-625

  Reiner, Steven L ^a   Sallusto, Federica ^b   Lanzavecchia, Antonio ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; IMMUNE RESPONSE; LABOR DIVISION;

CELL DIVISION; CELL FATE; CELL MATURATION; CELL STIMULATION; EFFECTOR CELL; GENETIC TRANSCRIPTION; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CYTOKINES; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 34547735648     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1143775     Document Type: Short Survey

References (24)

1. K. M. Murphy, S. L. Reiner, Nat. Rev. Immunol. 2, 933 (2002).
2. S. Sakaguchi, F. Powrie, Science 317, 627 (2007).
3. B. Stockinger, M. Veldhoen, Curr. Opin. Immunol. 19, 281 (2007).
4. C. G. Vinuesa, S. G. Tangye, B. Moser, C. R. Mackay, Nat. Rev. Immunol. 5, 853 (2005).
5. A. Peixoto et al., J. Exp. Med. 204, 1193 (2007).
6. F. Sallusto, D. Lenig, R. Forster, M. Lipp, A. Lanzavecchia, Nature 401, 708 (1999).
7. D. M. Catron, L. K. Rusch, J. Hataye, A. A. Itano, M. K. Jenkins, J. Exp. Med. 203, 1045 (2006).
8. A. O'Garra, P. Vieira, Nat. Rev. Immunol. 7, 425 (2007).
9. J. T. Chang et al., Science 315, 1687 (2007).
10. S. E. Henrickson, U. H. von Andrian, Curr. Opin. Immunol. 19, 249 (2007).
11. A. V. Gett, F. Sallusto, A. Lanzavecchia, J. Geginat, Nat. Immunol. 4, 355 (2003).
12. D. Mucida et al., Science 317, 256 (2007); published online 18 June 2007 (10.1126/science.1145697).
13. I. Ivanov et al., Cell 126, 1121 (2006).
14. M. Messi et al., Nat. Immunol. 4, 78 (2003).
15. J. J. Bird et al., Immunity 9, 229 (1998).
16. S. Celli, Z. Garcia, P. Bousso, J. Exp. Med. 202, 1271 (2005).
17. R. A. Maldonado, D. J. Irvine, R. Schreiber, L. H. Glimcher, Nature 431, 527 (2004).
18. K. Kretschmer et al., Nat. Immunol. 6, 1219 (2005).
19. V. P. Badovinac, J. S. Haring, J. T. Harty, Immunity 26, 827 (2007).
20. D. T. Fearon, P. Manders, S. D. Wagner, Science 293, 248 (2001).
21. Z. Garcia et al., Proc. Natl. Acad. Sci. U.S.A. 104, 4553 (2007).
22. J. Hataye, J. J. Moon, A. Khoruts, C. Reilly, M. K. Jenkins, Science 312, 114 (2006).
23. R. L. Reinhardt, S. Hong, S. J. Kang, Z. E. Wang, R. M. Locksley, J. Immunol. 177, 1618 (2006).
24. S.L.R. is grateful for support from the NIH and the Abramson Family. A.L. and F.S. are grateful for support from the Swiss National Science Foundation and the Helmut Horten Foundation.