메뉴 건너뛰기




Volumn 1, Issue 1, 2014, Pages 37-47

Interventions for Youth at Risk of Bipolar Disorder

Author keywords

Adolescent; Antidepressants; Antioxidants; Bipolar disorder; Clinical staging; Early intervention; High risk; Lithium; Mood disorders; Mood stabilizers; Novel treatment; Nutraceuticals; Prevention; Treatment

Indexed keywords


EID: 84921746465     PISSN: None     EISSN: 21963061     Source Type: Journal    
DOI: 10.1007/s40501-013-0006-x     Document Type: Review
Times cited : (7)

References (81)
  • 1
    • 77956912628 scopus 로고    scopus 로고
    • Clinical staging: a heuristic and practical strategy for new research and better health and social outcomes for psychotic and related mood disorders
    • This is a comprehensive review of key findings supporting that clinical staging is an important framework to refine mood and psychotic disorders and includes a discussion of the advantages of this diagtic approach
    • McGorry PD, Nelson B, Goldstone S, Yung AR. Clinical staging: a heuristic and practical strategy for new research and better health and social outcomes for psychotic and related mood disorders. Can J Psychiatr Rev Can Psychiatr. 2010;55(8):486–97. This is a comprehensive review of key findings supporting that clinical staging is an important framework to refine mood and psychotic disorders and includes a discussion of the advantages of this diagnostic approach.
    • (2010) Can J Psychiatr Rev Can Psychiatr , vol.55 , Issue.8 , pp. 486-497
    • McGorry, P.D.1    Nelson, B.2    Goldstone, S.3    Yung, A.R.4
  • 2
    • 84883173403 scopus 로고    scopus 로고
    • Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder
    • Pfaffenseller B, Fries GR, Wollenhaupt-Aguiar B, Colpo GD, Stertz L, Panizzutti B, et al. Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder. Expert Rev Neurother. 2013;13(7):827–42. This is a current concise overview of key candidate biomarkers related to bipolar disorder.
    • (2013) Expert Rev Neurother , vol.13 , Issue.7 , pp. 827
    • Pfaffenseller, B.1    Fries, G.R.2    Wollenhaupt-Aguiar, B.3    Colpo, G.D.4    Stertz, L.5    Panizzutti, B.6
  • 3
    • 0029598731 scopus 로고
    • Clinical course of affective disorders: were Emil Kraepelin and Jules Angst wrong?
    • PID: 8903893, This paper provides a cogent discussion as to how the diagis of Bipolar Disorder has changed over recent history and highlights the implications for treatment response and clinical course and progis
    • Grof P, Alda M, Ahrens B. Clinical course of affective disorders: were Emil Kraepelin and Jules Angst wrong? Psychopathology. 1995;28 Suppl 1:73–80. This paper provides a cogent discussion as to how the diagnosis of Bipolar Disorder has changed over recent history and highlights the implications for treatment response and clinical course and prognosis.
    • (1995) Psychopathology , vol.28 , pp. 73-80
    • Grof, P.1    Alda, M.2    Ahrens, B.3
  • 5
    • 70450197768 scopus 로고    scopus 로고
    • Early course of bipolar disorder in high-risk offspring: prospective study
    • Duffy A, Alda M, Hajek T, Grof P. Early course of bipolar disorder in high-risk offspring: prospective study. Br J Psychiatry: J Ment Sci. 2009;195(5):457–8.
    • (2009) Br J Psychiatry: J Ment Sci , vol.195 , Issue.5 , pp. 457-458
    • Duffy, A.1    Alda, M.2    Hajek, T.3    Grof, P.4
  • 7
    • 77649218193 scopus 로고    scopus 로고
    • Severe mental disorders in offspring with 2 psychiatrically ill parents
    • PID: 20194825, This paper describes a large population-based study from Denmark showing the risk to age 52 offspring with either no affected, 1 affected or 2 affected parents with either bipolar disorder or schizophrenia. It demonstrates that bipolar disorder risk is very much determined by a positive family history and that the illness starts to manifest during adolescence. It also demonstrates the importance of taking into account the major depression as part of the bipolar phenotype at-risk youth
    • Gottesman II, Laursen TM, Bertelsen A, Mortensen PB. Severe mental disorders in offspring with 2 psychiatrically ill parents. Arch Gen Psychiatry. 2010;67(3):252–7. This paper describes a large population-based study from Denmark showing the risk to age 52 in offspring with either no affected, 1 affected or 2 affected parents with either bipolar disorder or schizophrenia. It demonstrates that bipolar disorder risk is very much determined by a positive family history and that the illness starts to manifest during adolescence. It also demonstrates the importance of taking into account the major depression as part of the bipolar phenotype in at-risk youth.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.3 , pp. 252-257
    • Gottesman, I.I.1    Laursen, T.M.2    Bertelsen, A.3    Mortensen, P.B.4
  • 8
    • 0034666204 scopus 로고    scopus 로고
    • Historical perspectives and natural history of bipolar disorder
    • PID: 11018218, COI: 1:STN:280:DC%2BD3M7gvFKisg%3D%3D
    • Angst J, Sellaro R. Historical perspectives and natural history of bipolar disorder. Biol Psychiatry. 2000;48(6):445–57.
    • (2000) Biol Psychiatry , vol.48 , Issue.6 , pp. 445-457
    • Angst, J.1    Sellaro, R.2
  • 9
    • 22044431860 scopus 로고    scopus 로고
    • Manic-Depressive Illness: Evolution in Kraepelin's Textbook, 1883–1926
    • May/June, This is a very thorough and fasincating historical account of the development of Kraepelin's observations and how these shaped his thinking of the natural history of psychiatric illness and the basis upon which he drew categorical divisions
    • Trede KS, P.; Baethge, C.; Gerhard, A.; Maggini, C; Baldessarini, R.J. Manic-Depressive Illness: evolution in Kraepelin's Textbook, 1883–1926. Harv Rev Psychiatry. 2005(May/June):155–78.This is a very thorough and fasincating historical account of the development of Kraepelin's observations and how these shaped his thinking of the natural history of psychiatric illness and the basis upon which he drew categorical divisions.
    • (2005) Harv Rev Psychiatry , pp. 155-178
    • Trede, K.S.P.1    Baethge, C.2    Gerhard, A.3    Maggini, C.4    Baldessarini, R.J.5
  • 10
    • 22144435565 scopus 로고    scopus 로고
    • The impact of lithium long-term medication on suicidal behavior and mortality of bipolar patients
    • PID: 16020173
    • Muller-Oerlinghausen B, Felber W, Berghofer A, Lauterbach E, Ahrens B. The impact of lithium long-term medication on suicidal behavior and mortality of bipolar patients. Arch Suicide Res. 2005;9(3):307–19.
    • (2005) Arch Suicide Res , vol.9 , Issue.3 , pp. 307-319
    • Muller-Oerlinghausen, B.1    Felber, W.2    Berghofer, A.3    Lauterbach, E.4    Ahrens, B.5
  • 11
    • 84886549318 scopus 로고    scopus 로고
    • Fighting on the side of life: a special issue on suicide in bipolar disorder
    • PID: 23919261
    • Baethge C, Cassidy F. Fighting on the side of life: a special issue on suicide in bipolar disorder. Bipolar Disord. 2013;15(5):453–6.
    • (2013) Bipolar Disord , vol.15 , Issue.5 , pp. 453-456
    • Baethge, C.1    Cassidy, F.2
  • 12
    • 18744385560 scopus 로고    scopus 로고
    • Substance abuse in first-episode bipolar I disorder: indications for early intervention
    • PID: 15863809
    • Baethge C, Baldessarini RJ, Khalsa HM, Hennen J, Salvatore P, Tohen M. Substance abuse in first-episode bipolar I disorder: indications for early intervention. Am J Psychiatry. 2005;162(5):1008–10.
    • (2005) Am J Psychiatry , vol.162 , Issue.5 , pp. 1008-1010
    • Baethge, C.1    Baldessarini, R.J.2    Khalsa, H.M.3    Hennen, J.4    Salvatore, P.5    Tohen, M.6
  • 13
    • 78649938042 scopus 로고    scopus 로고
    • Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors
    • PID: 20934453, COI: 1:CAS:528:DC%2BC3cXhsFCrurvO, This paper summarizes the evidence regarding promising neurobiological pathways related to established illness progression and burden of illness patients with bipolar disorder. The paper focuses on end-stage broadly defined bipolar disorder and highlights the need for such studies high-risk youth order to identify primary disease markers and separate these from burden of illness effects
    • Berk M, Kapczinski F, Andreazza AC, Dean OM, Giorlando F, Maes M, et al. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci Biobehav Rev. 2011;35(3):804–17. This paper summarizes the evidence regarding promising neurobiological pathways related to established illness progression and burden of illness in patients with bipolar disorder. The paper focuses on end-stage broadly defined bipolar disorder and highlights the need for such studies in high-risk youth in order to identify primary disease markers and separate these from burden of illness effects.
    • (2011) Neurosci Biobehav Rev , vol.35 , Issue.3 , pp. 804-817
    • Berk, M.1    Kapczinski, F.2    Andreazza, A.C.3    Dean, O.M.4    Giorlando, F.5    Maes, M.6
  • 14
    • 66649091774 scopus 로고    scopus 로고
    • A critical appraisal of lithium's efficacy and effectiveness: the last 60 years
    • PID: 19538682, COI: 1:CAS:528:DC%2BD1MXhtVGit7jI, This is a very concise comprehensive review of the evidence supporting the clinical effectiveness of lithium various patient populations from the two authors with collectively the most experience using and studing lithium the world today
    • Grof P, Muller-Oerlinghausen B. A critical appraisal of lithium's efficacy and effectiveness: the last 60 years. Bipolar Disord. 2009;11 Suppl 2:10–9. This is a very concise comprehensive review of the evidence supporting the clinical effectiveness of lithium in various patient populations from the two authors with collectively the most experience using and studing lithium in the world today.
    • (2009) Bipolar Disord , vol.11 , pp. 10-19
    • Grof, P.1    Muller-Oerlinghausen, B.2
  • 15
    • 0035682590 scopus 로고    scopus 로고
    • Psychiatric diagnoses in the context of genetic studies of bipolar disorder
    • PID: 11843777, COI: 1:STN:280:DC%2BD387htVyisw%3D%3D
    • Duffy A, Grof P. Psychiatric diagnoses in the context of genetic studies of bipolar disorder. Bipolar Disord. 2001;3(6):270–5.
    • (2001) Bipolar Disord , vol.3 , Issue.6 , pp. 270-275
    • Duffy, A.1    Grof, P.2
  • 17
    • 35748956396 scopus 로고    scopus 로고
    • Prophylactic treatment response in bipolar disorder: results of a naturalistic observation study
    • PID: 17442400
    • Garnham J, Munro A, Slaney C, Macdougall M, Passmore M, Duffy A, et al. Prophylactic treatment response in bipolar disorder: results of a naturalistic observation study. J Affect Disord. 2007;104(1–3):185–90.
    • (2007) J Affect Disord , vol.104 , Issue.1-3 , pp. 185-190
    • Garnham, J.1    Munro, A.2    Slaney, C.3    Macdougall, M.4    Passmore, M.5    Duffy, A.6
  • 18
    • 77951973754 scopus 로고    scopus 로고
    • Sixty years of lithium responders
    • PID: 20453530, COI: 1:CAS:528:DC%2BC3cXmvFSqsbY%3D, A very good comprehensive review of a lifetime of work and learning from patients whose lives have been changed through effective treatment with lithium. This is a must read for any professional working with patients who warrant a trial of lithium treatment
    • Grof P. Sixty years of lithium responders. Neuropsychobiology. 2010;62(1):8–16. A very good comprehensive review of a lifetime of work and learning from patients whose lives have been changed through effective treatment with lithium. This is a must read for any professional working with patients who warrant a trial of lithium treatment.
    • (2010) Neuropsychobiology , vol.62 , Issue.1 , pp. 8-16
    • Grof, P.1
  • 19
    • 0033623241 scopus 로고    scopus 로고
    • The implications of genetics studies of major mood disorders for clinical practice
    • PID: 11030482, COI: 1:STN:280:DC%2BD3cvnvVOnsA%3D%3D
    • Duffy A, Grof P, Robertson C, Alda M. The implications of genetics studies of major mood disorders for clinical practice. J Clin Psychiatry. 2000;61(9):630–7.
    • (2000) J Clin Psychiatry , vol.61 , Issue.9 , pp. 630-637
    • Duffy, A.1    Grof, P.2    Robertson, C.3    Alda, M.4
  • 20
    • 34347250485 scopus 로고    scopus 로고
    • A consecutive series of treated affected offspring of parents with bipolar disorder: is response associated with the clinical profile?
    • Duffy A, Alda M, Milin R, Grof P. A consecutive series of treated affected offspring of parents with bipolar disorder: is response associated with the clinical profile? Can J Psychiatr Rev Can Psychiatr. 2007;52(6):369–76.
    • (2007) Can J Psychiatr Rev Can Psychiatr , vol.52 , Issue.6 , pp. 369-376
    • Duffy, A.1    Alda, M.2    Milin, R.3    Grof, P.4
  • 21
    • 61349108790 scopus 로고    scopus 로고
    • Maintenance treatment of adolescent bipolar disorder: open study of the effectiveness and tolerability of quetiapine
    • PID: 19200370, COI: 1:CAS:528:DC%2BD1MXitFOnsb0%3D
    • Duffy A, Milin R, Grof P. Maintenance treatment of adolescent bipolar disorder: open study of the effectiveness and tolerability of quetiapine. BMC Psychiatry. 2009;9:4.
    • (2009) BMC Psychiatry , vol.9 , pp. 4
    • Duffy, A.1    Milin, R.2    Grof, P.3
  • 22
    • 0036773679 scopus 로고    scopus 로고
    • Is response to prophylactic lithium a familial trait?
    • PID: 12416605, COI: 1:CAS:528:DC%2BD38Xosl2qsbo%3D
    • DA Grof P, Cavazzoni P, et al. Is response to prophylactic lithium a familial trait? J Clin Psychiatry. 2002;63:942–7.
    • (2002) J Clin Psychiatry , vol.63 , pp. 942-947
    • DA Grof, P.1    Cavazzoni, P.2
  • 23
    • 77953958066 scopus 로고    scopus 로고
    • The genetics of affective disorder and suicide
    • PID: 20462744, COI: 1:STN:280:DC%2BC3crgt1Siuw%3D%3D, A comprehensive overview of the key findings genetic studies related to bipolar disorder and suicide
    • McGuffin P, Perroud N, Uher R, Butler A, Aitchison KJ, Craig I, et al. The genetics of affective disorder and suicide. Eur Psychiatry. 2010;25(5):275–7. A comprehensive overview of the key findings in genetic studies related to bipolar disorder and suicide.
    • (2010) Eur Psychiatry , vol.25 , Issue.5 , pp. 275-277
    • McGuffin, P.1    Perroud, N.2    Uher, R.3    Butler, A.4    Aitchison, K.J.5    Craig, I.6
  • 24
    • 78650309711 scopus 로고    scopus 로고
    • Psychiatric 'diseases' versus behavioral disorders and degree of genetic influence
    • PID: 20459884, COI: 1:STN:280:DC%2BC3M%2FgvFCiuw%3D%3D
    • Bienvenu OJ, Davydow DS, Kendler KS. Psychiatric 'diseases' versus behavioral disorders and degree of genetic influence. Psychol Med. 2011;41(1):33–40.
    • (2011) Psychol Med , vol.41 , Issue.1 , pp. 33-40
    • Bienvenu, O.J.1    Davydow, D.S.2    Kendler, K.S.3
  • 25
    • 0035682236 scopus 로고    scopus 로고
    • Review of studies of child and adolescent offspring of bipolar parents
    • PID: 11843782, COI: 1:STN:280:DC%2BD387isVeqtg%3D%3D
    • DelBello MP, Geller B. Review of studies of child and adolescent offspring of bipolar parents. Bipolar Disord. 2001;3(6):325–34.
    • (2001) Bipolar Disord , vol.3 , Issue.6 , pp. 325-334
    • DelBello, M.P.1    Geller, B.2
  • 26
    • 77949344190 scopus 로고    scopus 로고
    • The early natural history of bipolar disorder: what we have learned from longitudinal high-risk research
    • A comprehensive overview of the key findings and resolved controversies the pediatric mania debate on the basis of complementary evidence from longitudinal high-risk studies
    • Duffy A. The early natural history of bipolar disorder: what we have learned from longitudinal high-risk research. Can J Psychiatr. 2010;55(8):477–85. A comprehensive overview of the key findings and resolved controversies in the pediatric mania debate on the basis of complementary evidence from longitudinal high-risk studies.
    • (2010) Can J Psychiatr , vol.55 , Issue.8 , pp. 477-485
    • Duffy, A.1
  • 28
    • 84882908039 scopus 로고    scopus 로고
    • Childhood anxiety: an early predictor of mood disorders in offspring of bipolar parents
    • PID: 23707033
    • Duffy A, Horrocks J, Doucette S, Keown-Stoneman C, McCloskey S, Grof P. Childhood anxiety: an early predictor of mood disorders in offspring of bipolar parents. J Affect Disord. 2013;150(2):363–9.
    • (2013) J Affect Disord , vol.150 , Issue.2 , pp. 363-369
    • Duffy, A.1    Horrocks, J.2    Doucette, S.3    Keown-Stoneman, C.4    McCloskey, S.5    Grof, P.6
  • 29
    • 80053542442 scopus 로고    scopus 로고
    • A high-risk study of bipolar disorder. Childhood clinical phenotypes as precursors of major mood disorders
    • PID: 21969459
    • Nurnberger JIJ, McInnis M, Reich W, Kastelic E, Wilcox HC, Glowinski A, et al. A high-risk study of bipolar disorder. Childhood clinical phenotypes as precursors of major mood disorders. Arch Gen Psychiatry. 2011;68(10):1012–20.
    • (2011) Arch Gen Psychiatry , vol.68 , Issue.10 , pp. 1012-1020
    • Nurnberger, J.I.J.1    McInnis, M.2    Reich, W.3    Kastelic, E.4    Wilcox, H.C.5    Glowinski, A.6
  • 30
    • 84892550642 scopus 로고    scopus 로고
    • The developmental trajectory of bipolar disorder
    • Summarizes findings in support of a clinical staging model describing the early natural history of bipolar disorder as it develops in high-risk children and adolescents
    • Duffy A, Horrocks J, Doucette S, Keown-Stoneman C, McCloskey S, Grof P. The developmental trajectory of bipolar disorder. Br J Psychiatry: J Ment Sci. 2013. Summarizes findings in support of a clinical staging model describing the early natural history of bipolar disorder as it develops in high-risk children and adolescents.
    • (2013) Br J Psychiatry: J Ment Sci.
    • Duffy, A.1    Horrocks, J.2    Doucette, S.3    Keown-Stoneman, C.4    McCloskey, S.5    Grof, P.6
  • 31
    • 84871822702 scopus 로고    scopus 로고
    • The nature of the association between childhood ADHD and the development of bipolar disorder: a review of prospective high-risk studies
    • PID: 23212056
    • Duffy A. The nature of the association between childhood ADHD and the development of bipolar disorder: a review of prospective high-risk studies. Am J Psychiatry. 2012;169(12):1247–55.
    • (2012) Am J Psychiatry , vol.169 , Issue.12 , pp. 1247-1255
    • Duffy, A.1
  • 32
    • 23044476506 scopus 로고    scopus 로고
    • Five-year prospective outcome of psychopathology in the adolescent offspring of bipolar parents
    • PID: 16026487
    • Hillegers MH, Reichart CG, Wals M, Verhulst FC, Ormel J, Nolen WA. Five-year prospective outcome of psychopathology in the adolescent offspring of bipolar parents. Bipolar Disord. 2005;7(4):344–50.
    • (2005) Bipolar Disord , vol.7 , Issue.4 , pp. 344-350
    • Hillegers, M.H.1    Reichart, C.G.2    Wals, M.3    Verhulst, F.C.4    Ormel, J.5    Nolen, W.A.6
  • 33
    • 0348111566 scopus 로고    scopus 로고
    • Earlier onset of bipolar disorder in children by antidepressants or stimulants? An hypothesis
    • PID: 14672801
    • Reichart CG, Nolen WA. Earlier onset of bipolar disorder in children by antidepressants or stimulants? An hypothesis. J Affect Disord. 2004;78(1):81–4.
    • (2004) J Affect Disord , vol.78 , Issue.1 , pp. 81-84
    • Reichart, C.G.1    Nolen, W.A.2
  • 34
    • 0034998787 scopus 로고    scopus 로고
    • Prior stimulant treatment in adolescents with bipolar disorder: association with age at onset
    • PID: 11333062, COI: 1:STN:280:DC%2BD3Mris1Gjuw%3D%3D
    • DelBello MP, Soutullo CA, Hendricks W, Niemeier RT, McElroy SL, Strakowski SM. Prior stimulant treatment in adolescents with bipolar disorder: association with age at onset. Bipolar Disord. 2001;3(2):53–7.
    • (2001) Bipolar Disord , vol.3 , Issue.2 , pp. 53-57
    • DelBello, M.P.1    Soutullo, C.A.2    Hendricks, W.3    Niemeier, R.T.4    McElroy, S.L.5    Strakowski, S.M.6
  • 35
    • 0027136893 scopus 로고
    • Unipolar relatives in bipolar pedigrees: a search for indicators of underlying bipolarity
    • PID: 8135302, COI: 1:STN:280:DyaK2c7ot1Klug%3D%3D
    • Blacker D, Lavori PW, Faraone SV, Tsuang MT. Unipolar relatives in bipolar pedigrees: a search for indicators of underlying bipolarity. Am J Med Genet. 1993;48(4):192–9.
    • (1993) Am J Med Genet , vol.48 , Issue.4 , pp. 192-199
    • Blacker, D.1    Lavori, P.W.2    Faraone, S.V.3    Tsuang, M.T.4
  • 36
    • 0020051408 scopus 로고
    • The Iowa 500: affective disorder in relatives of manic and depressed patients
    • PID: 7055292, COI: 1:STN:280:DyaL387htFaqsQ%3D%3D
    • Winokur G, Tsuang MT, Crowe RR. The Iowa 500: affective disorder in relatives of manic and depressed patients. Am J Psychiatry. 1982;139(2):209–12.
    • (1982) Am J Psychiatry , vol.139 , Issue.2 , pp. 209-212
    • Winokur, G.1    Tsuang, M.T.2    Crowe, R.R.3
  • 37
    • 72449176882 scopus 로고    scopus 로고
    • Early stages in the development of bipolar disorder
    • PID: 19541368
    • Duffy A, Alda M, Hajek T, Sherry SB, Grof P. Early stages in the development of bipolar disorder. J Affect Disord. 2010;121(1–2):127–35.
    • (2010) J Affect Disord , vol.121 , Issue.1-2 , pp. 127-135
    • Duffy, A.1    Alda, M.2    Hajek, T.3    Sherry, S.B.4    Grof, P.5
  • 38
    • 84868122760 scopus 로고    scopus 로고
    • Adolescent substance use disorder during the early stages of bipolar disorder: a prospective high-risk study
    • PID: 22959686
    • Duffy A, Horrocks J, Milin R, Doucette S, Persson G, Grof P. Adolescent substance use disorder during the early stages of bipolar disorder: a prospective high-risk study. J Affect Disord. 2012;142(1–3):57–64.
    • (2012) J Affect Disord , vol.142 , Issue.1-3 , pp. 57-64
    • Duffy, A.1    Horrocks, J.2    Milin, R.3    Doucette, S.4    Persson, G.5    Grof, P.6
  • 39
    • 49849087422 scopus 로고    scopus 로고
    • Sequencing of substance use and affective morbidity in 166 first-episode bipolar I disorder patients
    • PID: 18837869
    • Baethge C, Hennen J, Khalsa HM, Salvatore P, Tohen M, Baldessarini RJ. Sequencing of substance use and affective morbidity in 166 first-episode bipolar I disorder patients. Bipolar Disord. 2008;10(6):738–41.
    • (2008) Bipolar Disord , vol.10 , Issue.6 , pp. 738-741
    • Baethge, C.1    Hennen, J.2    Khalsa, H.M.3    Salvatore, P.4    Tohen, M.5    Baldessarini, R.J.6
  • 40
    • 70350441313 scopus 로고    scopus 로고
    • Intervention in individuals at ultra high risk for psychosis: A review and future directions
    • McGorry PD NB, Amminger GP, et al. Intervention in individuals at ultra high risk for psychosis: a review and future directions. J Clin Psychiatry. 2009.
    • (2009) J Clin Psychiatry
    • McGorry, P.D.N.B.1    Amminger, G.P.2
  • 41
    • 0036300575 scopus 로고    scopus 로고
    • First-episode mania: a neglected priority for early intervention
    • Conus P, McGorry PD. First-episode mania: a neglected priority for early intervention. Aust NZ J Psychiatry. 2002;36(2):158–72.
    • (2002) Aust NZ J Psychiatry , vol.36 , Issue.2 , pp. 158-172
    • Conus, P.1    McGorry, P.D.2
  • 42
    • 84876175841 scopus 로고    scopus 로고
    • Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value
    • Scott J, Leboyer M, Hickie I, Berk M, Kapczinski F, Frank E, et al. Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value. Br J Psychiatry: J Ment Sci. 2013;202(4):243–5.
    • (2013) Br J Psychiatry: J Ment Sci , vol.202 , Issue.4 , pp. 243-245
    • Scott, J.1    Leboyer, M.2    Hickie, I.3    Berk, M.4    Kapczinski, F.5    Frank, E.6
  • 43
    • 80053388898 scopus 로고    scopus 로고
    • Rumination-focused cognitive-behavioural therapy for residual depression: phase II randomised controlled trial
    • Watkins ER, Mullan E, Wingrove J, Rimes K, Steiner H, Bathurst N, et al. Rumination-focused cognitive-behavioural therapy for residual depression: phase II randomised controlled trial. Br J Psychiatry: J Ment Sci. 2011;199(4):317–22.
    • (2011) Br J Psychiatry: J Ment Sci , vol.199 , Issue.4 , pp. 317-322
    • Watkins, E.R.1    Mullan, E.2    Wingrove, J.3    Rimes, K.4    Steiner, H.5    Bathurst, N.6
  • 44
    • 33645097192 scopus 로고    scopus 로고
    • Psychotherapy for bipolar disorders - efficacy and effectiveness
    • PID: 16551672
    • Scott J. Psychotherapy for bipolar disorders - efficacy and effectiveness. J Psychopharmacol. 2006;20(2 Suppl):46–50.
    • (2006) J Psychopharmacol , vol.20 , pp. 46-50
    • Scott, J.1
  • 45
    • 84855898558 scopus 로고    scopus 로고
    • Functional impairment, stress, and psychosocial intervention in bipolar disorder
    • PID: 21830073
    • Miklowitz DJ. Functional impairment, stress, and psychosocial intervention in bipolar disorder. Curr Psychiatry Rep. 2011;13(6):504–12.
    • (2011) Curr Psychiatry Rep , vol.13 , Issue.6 , pp. 504-512
    • Miklowitz, D.J.1
  • 47
    • 79951471014 scopus 로고    scopus 로고
    • Early psychosocial intervention for youth at risk for bipolar I or II disorder: a one-year treatment development trial
    • PID: 21320254
    • Miklowitz DJ, Chang KD, Taylor DO, George EL, Singh MK, Schneck CD, et al. Early psychosocial intervention for youth at risk for bipolar I or II disorder: a one-year treatment development trial. Bipolar Disord. 2011;13(1):67–75.
    • (2011) Bipolar Disord , vol.13 , Issue.1 , pp. 67-75
    • Miklowitz, D.J.1    Chang, K.D.2    Taylor, D.O.3    George, E.L.4    Singh, M.K.5    Schneck, C.D.6
  • 48
    • 77956996479 scopus 로고    scopus 로고
    • From neuroprogression to neuroprotection: implications for clinical care
    • PID: 20712560
    • Berk M, Conus P, Kapczinski F, Andreazza AC, Yucel M, Wood SJ, et al. From neuroprogression to neuroprotection: implications for clinical care. Med J Aust. 2010;193(4 Suppl):S36–40.
    • (2010) Med J Aust , vol.193 , pp. S36-S40
    • Berk, M.1    Conus, P.2    Kapczinski, F.3    Andreazza, A.C.4    Yucel, M.5    Wood, S.J.6
  • 49
    • 84855908314 scopus 로고    scopus 로고
    • Is depression an inflammatory disorder?
    • PID: 21927805, This is an excellent summary of the evidence supporting the role of the central and peripheral immune system the development and recurrence of major depressive episodes and implications for novel treatments
    • Raison CL, Miller AH. Is depression an inflammatory disorder? Curr Psychiatry Rep. 2011;13(6):467–75. This is an excellent summary of the evidence supporting the role of the central and peripheral immune system in the development and recurrence of major depressive episodes and implications for novel treatments.
    • (2011) Curr Psychiatry Rep , vol.13 , Issue.6 , pp. 467-475
    • Raison, C.L.1    Miller, A.H.2
  • 50
    • 84875580072 scopus 로고    scopus 로고
    • Exercising the worry away: how inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours
    • PID: 23415701, COI: 1:CAS:528:DC%2BC3sXmtV2mtrw%3D
    • Moylan S, Eyre HA, Maes M, Baune BT, Jacka FN, Berk M. Exercising the worry away: how inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours. Neurosci Biobehav Rev. 2013;37(4):573–84.
    • (2013) Neurosci Biobehav Rev , vol.37 , Issue.4 , pp. 573-584
    • Moylan, S.1    Eyre, H.A.2    Maes, M.3    Baune, B.T.4    Jacka, F.N.5    Berk, M.6
  • 51
    • 84885484957 scopus 로고    scopus 로고
    • Association of exercise with quality of life and mood symptoms in a comparative effectiveness study of bipolar disorder
    • PID: 23993440
    • Sylvia LG, Friedman ES, Kocsis JH, Bernstein EE, Brody BD, Kinrys G, et al. Association of exercise with quality of life and mood symptoms in a comparative effectiveness study of bipolar disorder. J Affect Disord. 2013;151(2):722–7.
    • (2013) J Affect Disord , vol.151 , Issue.2 , pp. 722-727
    • Sylvia, L.G.1    Friedman, E.S.2    Kocsis, J.H.3    Bernstein, E.E.4    Brody, B.D.5    Kinrys, G.6
  • 52
    • 78651412528 scopus 로고    scopus 로고
    • Immune modulation of learning, memory, neural plasticity and neurogenesis
    • PID: 20970492, COI: 1:CAS:528:DC%2BC3MXhtVSru7w%3D
    • Yirmiya R, Goshen I. Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav Immun. 2011;25(2):181–213.
    • (2011) Brain Behav Immun , vol.25 , Issue.2 , pp. 181-213
    • Yirmiya, R.1    Goshen, I.2
  • 53
    • 84870930692 scopus 로고    scopus 로고
    • Is bipolar disorder an inflammatory condition? The relevance of microglial activation
    • PID: 23196997
    • Stertz L, Magalhaes PV, Kapczinski F. Is bipolar disorder an inflammatory condition? The relevance of microglial activation. Curr Opin Psychiatry. 2013;26(1):19–26.
    • (2013) Curr Opin Psychiatry , vol.26 , Issue.1 , pp. 19-26
    • Stertz, L.1    Magalhaes, P.V.2    Kapczinski, F.3
  • 54
    • 84882282383 scopus 로고    scopus 로고
    • Evidence for a dysregulated immune system in the etiology of psychiatric disorders
    • PID: 23645137
    • Gibney SM, Drexhage HA. Evidence for a dysregulated immune system in the etiology of psychiatric disorders. J Neuroimmune Pharmacol. 2013;8(4):900–20.
    • (2013) J Neuroimmune Pharmacol , vol.8 , Issue.4 , pp. 900-920
    • Gibney, S.M.1    Drexhage, H.A.2
  • 55
    • 67649205987 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder
    • PID: 18771602, COI: 1:CAS:528:DC%2BD1MXkslKlsb4%3D
    • Kauer-Sant'Anna M, Kapczinski F, Andreazza AC, Bond DJ, Lam RW, Young LT, et al. Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder. Int J Neuropsychopharmacol. 2009;12(4):447–58.
    • (2009) Int J Neuropsychopharmacol , vol.12 , Issue.4 , pp. 447-458
    • Kauer-Sant'Anna, M.1    Kapczinski, F.2    Andreazza, A.C.3    Bond, D.J.4    Lam, R.W.5    Young, L.T.6
  • 56
    • 42049092538 scopus 로고    scopus 로고
    • A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
    • PID: 18391128, COI: 1:CAS:528:DC%2BD1cXltFyhtr0%3D, This is an important paper describing novel gene expression findings pro-inflammatory genes both parents with bipolar disorder and their high-risk offspring
    • Padmos RC, Hillegers MH, Knijff EM, Vonk R, Bouvy A, Staal FJ, et al. A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry. 2008;65(4):395–407. This is an important paper describing novel gene expression findings in pro-inflammatory genes in both parents with bipolar disorder and their high-risk offspring.
    • (2008) Arch Gen Psychiatry , vol.65 , Issue.4 , pp. 395-407
    • Padmos, R.C.1    Hillegers, M.H.2    Knijff, E.M.3    Vonk, R.4    Bouvy, A.5    Staal, F.J.6
  • 57
    • 84859886494 scopus 로고    scopus 로고
    • Biological indicators of illness risk in offspring of bipolar parents: targeting the hypothalamic-pituitary-adrenal axis and immune system
    • PID: 22182213
    • Duffy A, Lewitzka U, Doucette S, Andreazza A, Grof P. Biological indicators of illness risk in offspring of bipolar parents: targeting the hypothalamic-pituitary-adrenal axis and immune system. Early Interv Psychiatry. 2012;6(2):128–37.
    • (2012) Early Interv Psychiatry , vol.6 , Issue.2 , pp. 128-137
    • Duffy, A.1    Lewitzka, U.2    Doucette, S.3    Andreazza, A.4    Grof, P.5
  • 58
    • 33947656940 scopus 로고    scopus 로고
    • Signs of a higher prevalence of autoimmune thyroiditis in female offspring of bipolar parents
    • PID: 17140771, COI: 1:CAS:528:DC%2BD2sXjslGlt7Y%3D
    • Hillegers MH, Reichart CG, Wals M, Verhulst FC, Ormel J, Nolen WA, et al. Signs of a higher prevalence of autoimmune thyroiditis in female offspring of bipolar parents. Eur Neuropsychopharmacol. 2007;17(6–7):394–9.
    • (2007) Eur Neuropsychopharmacol , vol.17 , Issue.6-7 , pp. 394-399
    • Hillegers, M.H.1    Reichart, C.G.2    Wals, M.3    Verhulst, F.C.4    Ormel, J.5    Nolen, W.A.6
  • 59
    • 79958173135 scopus 로고    scopus 로고
    • Elevated daytime cortisol levels: a biomarker of subsequent major affective disorder?
    • PID: 21329985, COI: 1:CAS:528:DC%2BC3MXntlGnsrY%3D
    • Ellenbogen MA, Hodgins S, Linnen AM, Ostiguy CS. Elevated daytime cortisol levels: a biomarker of subsequent major affective disorder? J Affect Disord. 2011;132(1–2):265–9.
    • (2011) J Affect Disord , vol.132 , Issue.1-2 , pp. 265-269
    • Ellenbogen, M.A.1    Hodgins, S.2    Linnen, A.M.3    Ostiguy, C.S.4
  • 60
    • 0032498325 scopus 로고    scopus 로고
    • Depression, stress and immunological activation: the role of cytokines in depressive disorders
    • PID: 9472719, COI: 1:CAS:528:DyaK1cXlsVGmuw%3D%3D
    • Connor TJ, Leonard BE. Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci. 1998;62(7):583–606.
    • (1998) Life Sci , vol.62 , Issue.7 , pp. 583-606
    • Connor, T.J.1    Leonard, B.E.2
  • 61
    • 0033561306 scopus 로고    scopus 로고
    • Patterns of DST positivity in remitted affective disorders
    • PID: 10386185, COI: 1:STN:280:DyaK1Mzhtl2lsQ%3D%3D
    • Deshauer D, Grof E, Alda M, Grof P. Patterns of DST positivity in remitted affective disorders. Biol Psychiatry. 1999;45(8):1023–9.
    • (1999) Biol Psychiatry , vol.45 , Issue.8 , pp. 1023-1029
    • Deshauer, D.1    Grof, E.2    Alda, M.3    Grof, P.4
  • 62
    • 84857361203 scopus 로고    scopus 로고
    • Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression
    • PID: 22166399, COI: 1:CAS:528:DC%2BC38XisFWmtr4%3D
    • Maes M, Ringel K, Kubera M, Berk M, Rybakowski J. Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression. J Affect Disord. 2012;136(3):386–92.
    • (2012) J Affect Disord , vol.136 , Issue.3 , pp. 386-392
    • Maes, M.1    Ringel, K.2    Kubera, M.3    Berk, M.4    Rybakowski, J.5
  • 63
    • 70349562518 scopus 로고    scopus 로고
    • Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature
    • PID: 19497250
    • Goldstein BI, Kemp DE, Soczynska JK, McIntyre RS. Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature. J Clin Psychiatry. 2009;70(8):1078–90.
    • (2009) J Clin Psychiatry , vol.70 , Issue.8 , pp. 1078-1090
    • Goldstein, B.I.1    Kemp, D.E.2    Soczynska, J.K.3    McIntyre, R.S.4
  • 64
    • 84883560286 scopus 로고    scopus 로고
    • Oxidative stress and therapeutic implications in psychiatric disorders
    • COI: 1:CAS:528:DC%2BC3sXlvFSjsLY%3D
    • Zhang XY, Yao JK. Oxidative stress and therapeutic implications in psychiatric disorders. Prog Neuro-Psychopharmacol Biol Psychiatry. 2013;46:197–9.
    • (2013) Prog Neuro-Psychopharmacol Biol Psychiatry , vol.46 , pp. 197-199
    • Zhang, X.Y.1    Yao, J.K.2
  • 65
    • 84883558764 scopus 로고    scopus 로고
    • Antioxidants as potential therapeutics for neuropsychiatric disorders
    • COI: 1:CAS:528:DC%2BC3sXhsVKktbvO
    • Pandya CD, Howell KR, Pillai A. Antioxidants as potential therapeutics for neuropsychiatric disorders. Prog Neuro-Psychopharmacol Biol Psychiatry. 2013;46:214–23.
    • (2013) Prog Neuro-Psychopharmacol Biol Psychiatry , vol.46 , pp. 214-223
    • Pandya, C.D.1    Howell, K.R.2    Pillai, A.3
  • 66
    • 79851512462 scopus 로고    scopus 로고
    • N-acetyl cysteine add-on treatment for bipolar II disorder: a subgroup analysis of a randomized placebo-controlled trial
    • PID: 20800897, COI: 1:CAS:528:DC%2BC3MXhvVyrs7o%3D
    • Magalhaes PV, Dean OM, Bush AI, Copolov DL, Malhi GS, Kohlmann K, et al. N-acetyl cysteine add-on treatment for bipolar II disorder: a subgroup analysis of a randomized placebo-controlled trial. J Affect Disord. 2011;129(1–3):317–20.
    • (2011) J Affect Disord , vol.129 , Issue.1-3 , pp. 317-320
    • Magalhaes, P.V.1    Dean, O.M.2    Bush, A.I.3    Copolov, D.L.4    Malhi, G.S.5    Kohlmann, K.6
  • 67
    • 80055010828 scopus 로고    scopus 로고
    • The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial
    • PID: 21719110, COI: 1:CAS:528:DC%2BC3MXhsVSktL7J
    • Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, et al. The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial. J Affect Disord. 2011;135(1–3):389–94.
    • (2011) J Affect Disord , vol.135 , Issue.1-3 , pp. 389-394
    • Berk, M.1    Dean, O.2    Cotton, S.M.3    Gama, C.S.4    Kapczinski, F.5    Fernandes, B.S.6
  • 68
    • 84864794946 scopus 로고    scopus 로고
    • A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents
    • PID: 22706327
    • Gray KM, Carpenter MJ, Baker NL, DeSantis SM, Kryway E, Hartwell KJ, et al. A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents. Am J Psychiatry. 2012;169(8):805–12.
    • (2012) Am J Psychiatry , vol.169 , Issue.8 , pp. 805-812
    • Gray, K.M.1    Carpenter, M.J.2    Baker, N.L.3    DeSantis, S.M.4    Kryway, E.5    Hartwell, K.J.6
  • 69
    • 84961888302 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation changes intracellular phospholipase A activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis
    • Smesny S, Milleit B, Hipler UC, Milleit C, Schafer MR, Klier CM, et al. Omega-3 fatty acid supplementation changes intracellular phospholipase A activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis. Mol Psychiatry. 2013.
    • (2013) Mol Psychiatry
    • Smesny, S.1    Milleit, B.2    Hipler, U.C.3    Milleit, C.4    Schafer, M.R.5    Klier, C.M.6
  • 70
    • 84876242211 scopus 로고    scopus 로고
    • Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats
    • PID: 23614006, COI: 1:CAS:528:DC%2BC3sXmvVCrsr8%3D
    • Bernardi JR, Ferreira CF, Senter G, Krolow R, de Aguiar BW, Portella AK, et al. Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats. PLoS One. 2013;8(4):e62031.
    • (2013) PLoS One , vol.8 , Issue.4
    • Bernardi, J.R.1    Ferreira, C.F.2    Senter, G.3    Krolow, R.4    de Aguiar, B.W.5    Portella, A.K.6
  • 71
    • 70149115047 scopus 로고    scopus 로고
    • 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder
    • PID: 19568477
    • Andreazza AC, Kapczinski F, Kauer-Sant'Anna M, Walz JC, Bond DJ, Goncalves CA, et al. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J Psychiatry Neurosci. 2009;34(4):263–71.
    • (2009) J Psychiatry Neurosci , vol.34 , Issue.4 , pp. 263-271
    • Andreazza, A.C.1    Kapczinski, F.2    Kauer-Sant'Anna, M.3    Walz, J.C.4    Bond, D.J.5    Goncalves, C.A.6
  • 72
    • 84856086688 scopus 로고    scopus 로고
    • Update on omega-3 polyunsaturated fatty acids in early-stage psychotic disorders
    • COI: 1:CAS:528:DC%2BC3MXhs1ejsrfE
    • Amminger GP, McGorry PD. Update on omega-3 polyunsaturated fatty acids in early-stage psychotic disorders. Neuropsychopharmacol: Off Publ Am Coll Neuropsychopharmacol. 2012;37(1):309–10.
    • (2012) Neuropsychopharmacol: Off Publ Am Coll Neuropsychopharmacol , vol.37 , Issue.1 , pp. 309-310
    • Amminger, G.P.1    McGorry, P.D.2
  • 73
    • 76149102249 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial
    • PID: 20124114, COI: 1:CAS:528:DC%2BC3cXis1aisbo%3D, Important randomized placebo controlled 12-week trial of omega-3-fatty acids showing effectiveness preventing conversion to psychosis clinically high-risk individuals
    • Amminger GP, Schafer MR, Papageorgiou K, Klier CM, Cotton SM, Harrigan SM, et al. Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial. Arch Gen Psychiatry. 2010;67(2):146–54. Important randomized placebo controlled 12-week trial of omega-3-fatty acids showing effectiveness in preventing conversion to psychosis in clinically high-risk individuals.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.2 , pp. 146-154
    • Amminger, G.P.1    Schafer, M.R.2    Papageorgiou, K.3    Klier, C.M.4    Cotton, S.M.5    Harrigan, S.M.6
  • 74
    • 84881027641 scopus 로고    scopus 로고
    • Effect of omega-3 fatty acids for indicated prevention of young patients at risk for psychosis: when do they begin to be effective?
    • PID: 23778032
    • Mossaheb N, Schafer MR, Schlogelhofer M, Klier CM, Cotton SM, McGorry PD, et al. Effect of omega-3 fatty acids for indicated prevention of young patients at risk for psychosis: when do they begin to be effective? Schizophr Res. 2013;148(1–3):163–7.
    • (2013) Schizophr Res , vol.148 , Issue.1-3 , pp. 163-167
    • Mossaheb, N.1    Schafer, M.R.2    Schlogelhofer, M.3    Klier, C.M.4    Cotton, S.M.5    McGorry, P.D.6
  • 75
    • 0020348484 scopus 로고
    • Predictors of bipolar illness in adolescents with major depression: a follow-up investigation
    • PID: 7171103, COI: 1:STN:280:DyaL3s3gtFylsg%3D%3D, An important sentinel paper identifying clinical predictors of bipolarity depressed adolescents
    • Strober M, Carlson G. Predictors of bipolar illness in adolescents with major depression: a follow-up investigation. Adolesc Psychiatry. 1982;10:299–319. An important sentinel paper identifying clinical predictors of bipolarity in depressed adolescents.
    • (1982) Adolesc Psychiatry , vol.10 , pp. 299-319
    • Strober, M.1    Carlson, G.2
  • 76
    • 85065206168 scopus 로고    scopus 로고
    • Antidepressant tolerability in anxious and depressed youth at high risk for bipolar disorder: A prospective naturalistic treatment study
    • Strawn JR, Adler CM, McNamara RK, Welge JA, Bitter SM, Mills NP, et al. Antidepressant tolerability in anxious and depressed youth at high risk for bipolar disorder: a prospective naturalistic treatment study. Bipolar Disord. 2013.
    • (2013) Bipolar Disord
    • Strawn, J.R.1    Adler, C.M.2    McNamara, R.K.3    Welge, J.A.4    Bitter, S.M.5    Mills, N.P.6
  • 77
    • 84872410156 scopus 로고    scopus 로고
    • Beyond the guidelines for bipolar disorder: practical issues in long-term treatment with lithium
    • Calkin C, Alda M. Beyond the guidelines for bipolar disorder: practical issues in long-term treatment with lithium. Can J Psychiatr Rev Can Psychiatr. 2012;57(7):437–45.
    • (2012) Can J Psychiatr Rev Can Psychiatr , vol.57 , Issue.7 , pp. 437-445
    • Calkin, C.1    Alda, M.2
  • 78
    • 70349671440 scopus 로고    scopus 로고
    • Lithium response across generations
    • PID: 19807719, COI: 1:CAS:528:DC%2BD1MXhtlyqur7J
    • Grof P, Duffy A, Alda M, Hajek T. Lithium response across generations. Acta Psychiatr Scand. 2009;120(5):378–85.
    • (2009) Acta Psychiatr Scand , vol.120 , Issue.5 , pp. 378-385
    • Grof, P.1    Duffy, A.2    Alda, M.3    Hajek, T.4
  • 79
    • 60349124065 scopus 로고    scopus 로고
    • Long-term effectiveness of lithium in bipolar disorder: a multicenter investigation of patients with typical and atypical features
    • PID: 19026269
    • Berghofer A, Alda M, Adli M, Baethge C, Bauer M, Bschor T, et al. Long-term effectiveness of lithium in bipolar disorder: a multicenter investigation of patients with typical and atypical features. J Clin Psychiatry. 2008;69(12):1860–8.
    • (2008) J Clin Psychiatry , vol.69 , Issue.12 , pp. 1860-1868
    • Berghofer, A.1    Alda, M.2    Adli, M.3    Baethge, C.4    Bauer, M.5    Bschor, T.6
  • 80
    • 84873400499 scopus 로고    scopus 로고
    • The relationship between bipolar disorder and type 2 diabetes: more than just co-morbid disorders
    • PID: 22621171, COI: 1:CAS:528:DC%2BC3sXit1Wrsbo%3D
    • Calkin CV, Gardner DM, Ransom T, Alda M. The relationship between bipolar disorder and type 2 diabetes: more than just co-morbid disorders. Ann Med. 2013;45(2):171–81.
    • (2013) Ann Med , vol.45 , Issue.2 , pp. 171-181
    • Calkin, C.V.1    Gardner, D.M.2    Ransom, T.3    Alda, M.4
  • 81
    • 0038397616 scopus 로고    scopus 로고
    • Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challenge
    • PID: 12742677, COI: 1:CAS:528:DC%2BD3sXjs1agsr4%3D
    • Gyulai L, Bauer M, Bauer MS, Garcia-Espana F, Cnaan A, Whybrow PC. Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challenge. Biol Psychiatry. 2003;53(10):899–905.
    • (2003) Biol Psychiatry , vol.53 , Issue.10 , pp. 899-905
    • Gyulai, L.1    Bauer, M.2    Bauer, M.S.3    Garcia-Espana, F.4    Cnaan, A.5    Whybrow, P.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.