The genetics of affective disorder and suicide

European Psychiatry

Volumn 25, Issue 5, 2010, Pages 275-277

  McGuffin, P ^a   Perroud, N ^a   Uher, R ^a   Butler, A ^a   Aitchison, K J ^a   Craig, I ^a   Lewis, C ^a   Farmer, A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Affective disorder; Genetics; Genome wide association studies (GWAS); Suicide

Indexed keywords

ARTICLE; BIPOLAR DISORDER; FAMILY STUDY; GENETIC ASSOCIATION; HERITABILITY; HUMAN; MAJOR DEPRESSION; MOOD DISORDER; PRIORITY JOURNAL; SUICIDAL BEHAVIOR; SUICIDAL IDEATION; SUICIDE; TWINS; GENETICS; SOCIAL ENVIRONMENT;

GENOME-WIDE ASSOCIATION STUDY; HUMANS; MOOD DISORDERS; SOCIAL ENVIRONMENT; SUICIDE;

EID: 77953958066     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2009.12.012     Document Type: Article

References (27)

1. Bellivier F., Chaste P., Malafosse A. Association between the TPH gene A218C polymorphism and suicidal behavior: a metaanalysis. Am J Med Genet B Neuropsychiatr Genet 2004, 124B:87-91.
2. Bertelsen A., Harvald B., Hauge M. A Danish twin study of manic-depressive disorders. Br J Psychiatry 1977, 130:330-351.
3. Brezo J., Bureau A., Mérette C., Jomphe V., Barker E.D., Vitaro F., et al. Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene-environment study. Mol Psychiatry 2009, 21. [Epub ahead of print].
4. Courtet P., Jollant F., Castelnau D., Buresi C., Malafosse A. Suicidal behavior: relationship between phenotype and serotonergic genotype. Am J Med Genet C Semin Med Genet 2005, 133C:25-33.
5. Escriba P.V., Ozaita A., Garcia-Sevilla J.A. Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims. Neuropsychopharmacology 2004, 29:1512-1521.
6. Farmer A., Harris T., Redman K., Sadler S., Mahmood A., McGuffin P. The Cardiff Depression Study - A sib pair study of life events and familiality in major depression. Br J Psychiatry 2000, 176:150-155.
7. Green E.K., Grozeva D., Jones I., Jones L., Kirov G., Caesar S., et al. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry 2009, 21. [Epub ahead of print].
8. Jones I., Craddock N. Bipolar disorder and childbirth: the importance of recognising risk. Br J Psychiatry 2005, 186:453-454.
9. Kendler K.S., Neale M.C., Kessler R.C., Heath A.C., Eaves L.J. Familial influences on the clinical characteristics of major depression: a twin study. Acta Psychiatr Scand 1992, 86:371-378.
10. Kendler K.S., Neale M.C., Kessler R.C., Heath A.C., Eaves L.J. The lifetime history of major depression in women: reliability of diagnosis and heritability. Arch Gen Psychiatry 1993, 50:863-870.
11. Laje G., Paddock S., Manji H., Rush A.J., Wilson A.F., Charney D., et al. Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry 2007, 164:1530-1538.
12. Li D., He L. Meta-analysis supports association between serotonin transporter (5-HTT) and suicidal behavior. Mol Psychiatry 2007, 12:47-54.
13. Mann J.J. Neurobiology of suicidal behaviour. Nat Rev Neurosci 2003, 4:819-828.
14. Marušič A., Roskar S., Hughes R.H. Familial study of suicide behaviour among adolescents in Slovenia. Crisis 2004, 25:74-77.
15. McGuffin P., Katz R. Nature, nurture and affective disorder. The Biology of Depression 1986, 25-51. Gaskell, London, UK. J.W.F. Deakin (Ed.).
16. McGuffin P., Katz R., Rutherford J., Watkins S. A hospital based twin register of the Heritability of DSM-IV Unipolar Depression. Arc Gen Psychiatry 1996, 53:129-136.
17. McGuffin P., Rijsdijk F., Andrew M., Sham P., Katz R., Cardno A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry 2003, 60:497-502.
18. McGuffin P., Knight J., Breen G., Brewster S., Boyd P., Craddock N., et al. Whole genome linkage scan of recurrent depressive disorder from the Depression Network Study. Hum Mol Genet 2005, 14(22):3337-3345.
19. Muglia P., Tozzi F., Galwey N.W., Francks C., UpmanyuR, Kong X.Q., et al. Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. Mol Psychiatry 2008, [December 23: Epub ahead of print].
20. Perlis R.H., Purcell S., Fava M., Fagerness J., Rush A.J., Trivedi M.H., et al. Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch Gen Psych 2007, 64:689-697.
21. Perroud N., Courtet P., Vincze I., Jaussent I., Jollant F., Bellivier F., et al. Interaction between BDNF Val66Met and childhood trauma on adults violent suicide attempt. Genes Brain Behav 2008, 7:314-322.
22. Perroud N., Uher R., Marusic A., Rietschel M., Mors O., Henigsberg N., et al. Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial. BMC Med 2009, 7:60.
23. Rice J.P., Rochberg N., Endicott J., Lavori P.W., Miller C. Stability of psychiatric diagnoses. An application to the affective disorders. Arch Gen Psychiatry 1992, 49:824-830.
24. Roy A., Segal N.I., Centerwall B.S., Robinette C.D. Suicide in twins. Arch Gen Psych 1991, 48:28-32.
25. Sequeira A., Mamdani F., Lalovic A., Anguelova M., Lesage A., Seguin M., et al. Alpha 2A adrenergic receptor gene and suicide. Psychiatry Res 2004, 125:87-93.
26. Sklar P., Smoller J.W., Fan J., Ferreira M.A., Perlis R.H., Chambert K., et al. Whole-genome association study of bipolar disorder. Mol Psychiatry 2008, 13:558-569.
27. Sullivan P.F., de Geus E.J., Willemsen G., James M.R., Smit J.H., Zandbelt T., et al. Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry 2009, 14:359-375.