Plasma phospholipid and dietary α-linolenic acid, mortality, CHD and stroke: The Cardiovascular Health Study

British Journal of Nutrition

Volumn 112, Issue 7, 2014, Pages 1206-1213

  Fretts, Amanda M ^a   Mozaffarian, Dariush ^b   Siscovick, David S ^a   Sitlani, Colleen ^a   Psaty, Bruce M ^a   Rimm, Eric B ^b   Song, Xiaoling ^c   McKnight, Barbara ^a   Spiegelman, Donna ^b   King, Irena B ^d   Lemaitre, Rozenn N ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HARVARD UNIVERSITY   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

CVD; Fatty acids; Mortality; Linolenic acid

Indexed keywords

LINOLENIC ACID; PHOSPHOLIPID;

AGED; ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; DISEASE ASSOCIATION; FAT INTAKE; FEMALE; FOLLOW UP; HUMAN; ISCHEMIC HEART DISEASE; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; NUTRITIONAL ASSESSMENT; PHOSPHOLIPID BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR; BLOOD; CARDIOVASCULAR DISEASES; CORONARY DISEASE; DIET; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; STROKE; UNITED STATES;

AGED; ALPHA-LINOLENIC ACID; CARDIOVASCULAR DISEASES; COHORT STUDIES; CORONARY DISEASE; DIET; FEMALE; HUMANS; MALE; MORTALITY; PHOSPHOLIPIDS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; STROKE; UNITED STATES;

EID: 84921742958     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114514001925     Document Type: Article

References (48)

1. Harris WS, Kris-Etherton PM & Harris KA (2008) Intakes of long-chain omega-3 fatty acid associated with reduced risk for death from coronary heart disease in healthy adults. Curr Atheroscler Rep 10, 503-509.
2. Harris WS, Poston WC & Haddock CK (2007) Tissue n-3 and n-6 fatty acids and risk for coronary heart disease events. Atherosclerosis 193, 1-10.
3. Albert CM, Campos H, Stampfer MJ, et al. (2002) Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med 346, 1113-1118.
4. Albert CM, Hennekens CH, O'Donnell CJ, et al. (1998) Fish consumption and risk of sudden cardiac death. JAMA 279, 23-28.
5. Lemaitre RN, King IB, Mozaffarian D, et al. (2003) n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr 77, 319-325.
6. Burr ML, Fehily AM, Gilbert JF, et al. (1989) Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet ii, 757-761.
7. Wang C, Harris WS, Chung M, et al. (2006) n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primaryand secondary-prevention studies: a systematic review. Am J Clin Nutr 84, 5-17.
8. Bushkin-Bedient S & Carpenter DO (2010) Benefits versus risks associated with consumption of fish and other seafood. Rev Environ Health 25, 161-191.
9. Lenihan-Geels G, Bishop KS & Ferguson LR (2013) Alternative sources of omega-3 fats: can we find a sustainable substitute for fish? Nutrients 5, 1301-1315.
10. Fried LP, Borhani NO, Enright P, et al. (1991) The Cardiovascular Health Study: design and rationale. Ann Epidemiol 1, 263-276.
11. Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497-509.
12. Lepage G & Roy CC (1986) Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27, 114-120.
13. Djousse L, Biggs ML, Lemaitre RN, et al. (2011) Plasma omega-3 fatty acids and incident diabetes in older adults. Am J Clin Nutr 94, 527-533.
14. Feskanich D, Rimm EB, Giovannucci EL, et al. (1993) Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire. J Am Diet Assoc 93, 790-796.
15. Lemaitre RN, Sitlani C, Song X, et al. (2012) Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study. Am J Clin Nutr 96, 269-274.
16. Fretts AM, Mozaffarian D, Siscovick DS, et al. (2013) Associations of plasma phospholipid and dietary alpha linolenic acid with incident atrial fibrillation in older adults: the Cardiovascular Health Study. J Am Heart Assoc 2, e003814.
17. Ives DG, Fitzpatrick AL, Bild DE, et al. (1995) Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study. Ann Epidemiol 5, 278-285.
18. Willet W (1998) Nutritional Epidemiology. New York: Oxford University Press.
19. Goyens PL, Spilker ME, Zock PL, et al. (2006) Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. Am J Clin Nutr 84, 44-53.
20. Baylin A, Ruiz-Narvaez E, Kraft P, et al. (2007) Alphalinolenic acid, delta(6)-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. Am J Clin Nutr 85, 554-560.
21. Mozaffarian D, Ascherio A, Hu FB, et al. (2005) Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. Circulation 111, 157-164.
22. du Toit PJ, van Aswegen CH & du Plessis DJ (1996) The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells. Prostaglandins Leukot Essent Fatty Acids 55, 173-177.
23. Kamano K, Okuyama H, Konishi R, et al. (1989) Effects of a high-linoleate and a high-alpha-linolenate diet on spontaneous mammary tumourigenesis in mice. Anticancer Res 9, 1903-1908.
24. Fritsche KL & Johnston PV (1990) Effect of dietary alphalinolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas. J Nutr 120, 1601-1609.
25. Bourre JM (2004) Roles of unsaturated fatty acids (especially omega-3 fatty acids) in the brain at various ages and during ageing. J Nutr Health Aging 8, 163-174.
26. Gerber M (2012) Omega-3 fatty acids and cancers: a systematic update review of epidemiological studies. Br J Nutr 107, Suppl. 2, S228-S239.
27. Geleijnse JM, Giltay EJ & Kromhout D (2012) Effects of n-3 fatty acids on cognitive decline: a randomized, doubleblind, placebo-controlled trial in stable myocardial infarction patients. Alzheimers Dement 8, 278-287.
28. Kim M, Nam JH, Oh DH, et al. (2010) Erythrocyte α-linolenic acid is associated with the risk for mild dementia in Korean elderly. Nutr Res 30, 756-761.
29. Cherubini A, Andres-Lacueva C, Martin A, et al. (2007) Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci 62, 1120-1126.
30. Simon JA, Fong J, Bernert JT Jr, et al. (1995) Serum fatty acids and the risk of stroke. Stroke 26, 778-782.
31. Park Y, Park S, Yi H, et al. (2009) Low level of n-3 polyunsaturated fatty acids in erythrocytes is a risk factor for both acute ischemic and hemorrhagic stroke in Koreans. Nutr Res 29, 825-830.
32. Khaw KT, Friesen MD, Riboli E, et al. (2012) Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk Prospective Study. PLoS Med 9, e1001255.
33. Wang L, Folsom AR & Eckfeldt JH (2003) Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. Nutr Metab Cardiovasc Dis 13, 256-266.
34. Wiberg B, Sundstrom J, Arnlov J, et al. (2006) Metabolic risk factors for stroke and transient ischemic attacks in middleaged men - a community-based study with long-term follow-up. Stroke 37, 2898-2903.
35. Warensjo E, Sundstrom J, Vessby B, et al. (2008) Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: a population-based prospective study. Am J Clin Nutr 88, 203-209.
36. Pan A, Chen M, Chowdhury R, et al. (2012) α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. Am J Clin Nutr 96, 1262-1273.
37. Folsom AR & Demissie Z (2004) Fish intake, marine omega-3 fatty acids, and mortality in a cohort of postmenopausal women. Am J Epidemiol 160, 1005-1010.
38. Oomen CM, Ocke MC, Feskens EJ, et al. (2001) Alphalinolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study. Am J Clin Nutr 74, 457-463.
39. de Goede J, Verschuren WM, Boer JM, et al. (2011) Alphalinolenic acid intake and 10-year incidence of coronary heart disease and stroke in 20,000 middle-aged men and women in the Netherlands. PLoS ONE 6, e17967.
40. Pietinen P, Ascherio A, Korhonen P, et al. (1997) Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am J Epidemiol 145, 876-887.
41. Ascherio A, Rimm EB, Giovannucci EL, et al. (1996) Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. BMJ 313, 84-90.
42. Albert CM, Oh K, Whang W, et al. (2005) Dietary alphalinolenic acid intake and risk of sudden cardiac death and coronary heart disease. Circulation 112, 3232-3238.
43. Vedtofte MS, Jakobsen MU, Lauritzen L, et al. (2011) Dietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. Am J Clin Nutr 94, 1097-1103.
44. Laaksonen DE, Nyyssonen K, Niskanen L, et al. (2005) Prediction of cardiovascular mortality in middle-aged men by dietary and serum linoleic and polyunsaturated fatty acids. Arch Intern Med 165, 193-199.
45. Brouwer IA, Katan MB & Zock PL (2004) Dietary alphalinolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 134, 919-922.
46. Larsson SC, Virtamo J & Wolk A (2012) Dietary fats and dietary cholesterol and risk of stroke in women. Atherosclerosis 221, 282-286.
47. He K, Rimm EB, Merchant A, et al. (2002) Fish consumption and risk of stroke in men. JAMA 288, 3130-3136.
48. Hu FB, Stampfer MJ, Manson JAE, et al. (1999) Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr 69, 890-897.