Dietary α-Linolenic Acid Is Associated with Reduced Risk of Fatal Coronary Heart Disease, but Increased Prostate Cancer Risk: A Meta-Analysis

Journal of Nutrition

Volumn 134, Issue 4, 2004, Pages 919-922

  Brouwer, Ingeborg A ^a   Katan, Martijn B ^a   Zock, Peter L ^a  

^a NONE

Author keywords

(n 3) fatty acids; Cardiovascular; Linolenic acid; Meta analysis; Prostate cancer

Indexed keywords

FATTY ACID; LINOLEIC ACID; VEGETABLE OIL;

CANCER RISK; CARDIOVASCULAR RISK; CLINICAL TRIAL; CONFERENCE PAPER; CORONARY RISK; DIETARY INTAKE; FOOD INTAKE; HEART DISEASE; HEART PROTECTION; HUMAN; ISCHEMIC HEART DISEASE; META ANALYSIS; MORTALITY; PROSTATE CARCINOMA; RISK FACTOR;

EID: 1842530392     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/134.4.919     Document Type: Conference Paper

References (31)

1. GISSI-Prevenzione Investigators (1999) Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354: 447-455.
2. Burr, M. L., Fehily, A. M., Gilbert, J. F., Rogers, S., Holliday, R. M., Sweetnam, P. M., Elwood, P. C. & Deadman, N. M. (1989) Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 2: 757-761.
3. de-Lorgeril, M., Renaud, S., Mamelle, N., Salen, P., Martin, J. L., Monjaud, I., Guidollet, J., Touboul, P. & Delaye, J. (1994) Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 343: 1454-1459.
4. Kromhout, D., Bosschieter, E. B. & de-Lezenne-Coulander, C. (1985) The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N. Engl. J. Med. 312: 1205-1209.
5. Albert, C. M., Hennekens, C. H., O'Donnell, C. J., Ajani, U. A., Carey, V. J., Willett, W. C., Ruskin, J. N. & Manson, J. E. (1998) Fish consumption and risk of sudden cardiac death. J. Am. Med. Assoc. 279: 23-28.
6. Hu, F. B., Bronner, L., Willett, W. C., Stampfer, M. J., Rexrode, K. M., Albert, C. M., Hunter, D. & Manson, J. E. (2002) Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. J. Am. Med. Assoc. 287: 1815-1821.
7. Voskuil, D. W., Feskens, E. J., Katan, M. B. & Kromhout, D. (1996) Intake and sources of alpha-linolenic acid in Dutch elderly men. Eur. J. Clin. Nutr. 50: 784-787.
8. Giovannucci, E., Rimm, E. B., Colditz, G. A., Stampfer, M. J., Ascherio, A., Chute, C. C. & Willett, W. C. (1993) A prospective study of dietary fat and risk of prostate cancer. J. Natl. Cancer Inst. 85: 1571-1579.
9. Naylor, R. L., Goldburg, R. J., Primavera, J. H., Kautsky, N., Beveridge, M. C., Clay, J., Folke, C., Lubchenco, J., Mooney, H. & Troell, M. (2000) Effect of aquaculture on world fish supplies. Nature (Lond.) 405: 1017-1024.
10. DerSimonian, R. & Laird, N. (1986) Meta-analysis in clinical trials. Control Clin. Trials 7: 177-188.
11. Dolecek, T. A. & Granditis, G. (1991) Dietary polyunsaturated fatty acids and mortality in the Multiple Risk Factor Intervention Trial (MRFIT). World Rev. Nutr. Diet. 66: 205-216.
12. Ascherio, A., Rimm, E. B., Giovannucci, E. L., Spiegelman, D., Stampfer, M. & Willett, W.C. (1996) Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. Br. Med. J. 313: 84-90.
13. Pietinen, P., Ascherio, A., Korhonen, P., Hartman, A. M., Willett, W. C., Albanes, D. & Virtamo, J. (1997) Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am. J. Epidemiol. 145: 876-887.
14. Hu, F. B., Stampfer, M. J., Manson, J. E., Rimm, E. B., Wolk, A., Colditz, G. A., Hennekens, C. H. & Willett, W. C. (1999) Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Am. J. Clin. Nutr. 69: 890-897.
15. Oomen, C. M., Ocke, M. C., Feskens, E. J., Kok, F. J. & Kromhout, D. (2001) α-Linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study. Am. J. Clin. Nutr. 74: 457-463.
16. Singh, R. B., Niaz, M. A., Sharma, J. P., Kumar, R., Rastogi, V. & Moshiri, M. (1997) Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival - 4. Cardiovasc. Drugs Ther. 11: 485-491.
17. Singh, R. B., Dubnov, G., Niaz, M. A., Ghosh, S., Singh, R., Rastogi, S. S., Manor, O., Pella, D. & Berry, E. M. (2002) Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial. Lancet 360: 1455-1461.
18. Leaf, A., Kang, J. X., Xiao, Y. F. & Billman, G. E. (1999) n-3 Fatty acids in the prevention of cardiac arrhythmias. Lipids 34 (suppl.):S187-S189.
19. McLennan, P. L. & Dallimore, J. A. (1995) Dietary canola oil modifies myocardial fatty acids and inhibits cardiac arrhythmias in rats. J. Nutr. 125: 1003-1009.
20. Gann, P. H., Hennekens, C. H., Sacks, F. M., Grodstein, F., Giovannucci, E. L. & Stampfer, M. J. (1994) Prospective study of plasma fatty acids and risk of prostate cancer. J. Natl. Cancer Inst. 86: 281-286.
21. Harvei, S., Bjerve, K. S., Tretli, S., Jellum, E., Robsahm, T. E. & Vatten, L. (1997) Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. Int. J. Cancer 71: 545-551.
22. Schuurman, A. G., van-den-Brandt, P. A., Dorant, E., Brants, H. A. & Goldbohm, R. A. (1999) Association of energy and fat intake with prostate carcinoma risk: results from The Netherlands Cohort Study. Cancer 86: 1019-1027.
23. Ramon, J. M., Bou, R., Romea, S., Alkiza, M. E., Jacas, M., Ribes, J. & Oromi, J. (2000) Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 11: 679-685.
24. De-Stefani, E., Deneo-Pellegrini, H., Boffetta, P., Ronco, A. & Mendilaharsu, M. (2000) Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol. Biomark. Prev. 9: 335-338.
25. Godley, P. A., Campbell, M. K., Miller, C., Gallagher, P., Martinson, F. E., Mohler, J. L. & Sandler, R. S. (1996) Correlation between biomarkers of omega-3 fatty acid consumption and questionnaire data in African American and Caucasian United States males with and without prostatic carcinoma. Cancer Epidemiol. Biomark. Prev. 5: 115-119.
26. Newcomer, L. M., King, I. B., Wicklund, K. G. & Stanford, J. L. (2001) The association of fatty acids with prostate cancer risk. Prostate 47: 262-268.
27. Andersson, S. O., Wolk, A., Bergstrom, R., Giovannucci, E., Lindgren, C., Baron, J. & Adami, H. O. (1996) Energy, nutrient intake and prostate cancer risk: a population-based case-control study in Sweden. Int. J. Cancer 68: 716-722.
28. Bjerve, K. S., Brubakk, A. M., Fougner, K. J., Johnsen, H., Midthjell, K. & Vik, T. (1993) Omega-3 fatty acids: essential fatty acids with important biological effects, and serum phospholipid fatty acids as markers of dietary omega 3-fatty acid intake. Am. J. Clin. Nutr. 57: 801S-805S.
29. Zipes, D. P. & Wellens, H. J. (1998) Sudden cardiac death. Circulation 98: 2334-2351.
30. Huikuri, H. V., Castellanos, A. & Myerburg, R. J. (2001) Sudden death, due to cardiac arrhythmias. N. Engl. J. Med. 345: 1473-1482.
31. Augustsson, K., Michaud, D. S., Rimm, E. B., Leitzmann, M. F., Stampfer, M. J., Willett, W. C. & Giovannucci, E. (2003) A prospective study of intake of fish and marine fatty acids and prostate cancer. Cancer Epidemiol. Biomark. Prev. 12: 64-67.