Mouse models of allergic asthma

Mast Cells: Methods and Protocols

Volumn , Issue , 2014, Pages 503-519

  Gold, Matthew ^a   Marsolais, David ^b   Blanchet, Marie Renee ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Asthma; Bronchoalveolar lavage; House dust mite; Inflammation; Intranasal; Mouse; Ovalbumin

Indexed keywords

EID: 84921734232     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4939-1568-2_31     Document Type: Chapter

References (26)

1. Barnes PJ (2008) Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 8:183-192. doi:10.1038/nri2254.
2. Lee JJ et al (2004) Defining a link with asthma in mice congenitally deficient in eosinophils. Science 305:1773-1776. doi:10.1126/science.1099472.
3. Fulkerson PC et al (2006) A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proc Natl Acad Sci U S A 103:16418-16423. doi:10.1073/pnas.0607863103.
4. Walsh ER et al (2008) Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma. J Exp Med 205:1285-1292. doi:10.1084/jem.20071836.
5. Fattouh R et al (2011) Eosinophils are dispensable for allergic remodeling and immunity in a model of house dust mite-induced airway disease. Am J Respir Crit Care Med 183:179-188. doi:10.1164/rccm.200905-0736OC.
6. Corry DB et al (1998) Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice. Mol Med 4:344-355.
7. Becker M et al (2011) Genetic variation determines mast cell functions in experimental asthma. J Immunol 186:7225-7231. doi:10.4049/jimmunol.1100676.
8. Nakae S et al (2007) Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice. J Allergy Clin Immunol 120:48-55. doi:10.1016/j.jaci.2007.02.046.
9. Desquand S, Lefort J, Liu FT, Mencia-Huerta JM, Vargaftig BB (1989) Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies. Int Arch Allergy Appl Immunol 89:71-77.
10. Sertl K, Kowalski ML, Slater J, Kaliner MA (1988) Passive sensitization and antigen challenge increase vascular permeability in rat airways. Am Rev Respir Dis 138:1295-1299.
11. Van Oosterhout AJ et al (1993) Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs. Am Rev Respir Dis 147:548-552.
12. Lopez E et al (2011) Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes. Mediators Inflamm 2011:823279. doi:10.1155/2011/823279.
13. Yu M et al (2011) Identification of an IFNgamma/mast cell axis in a mouse model of chronic asthma. J Clin Invest 121:3133-3143. doi:10.1172/jci43598.
14. Kung TT et al (1995) Mast cells modulate allergic pulmonary eosinophilia in mice. Am J Respir Cell Mol Biol 12:404-409.
15. Takeda K et al (1997) Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 186:449-454.
16. Williams CM, Galli SJ (2000) Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med 192:455-462.
17. Cho JY et al (2010) Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13. Respir Res 11:154. doi:10.1186/1465-9921-11-154.
18. Cho JY et al (2004) Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 113:551-560. doi:10.1172/jci19133.
19. O'Brien R, Ooi MA, Clarke AH, Thomas WR (1996) Immunologic responses following respiratory sensitization to house dust mite allergens in mice. Immunol Cell Biol 74:174-179. doi:10.1038/icb.1996.24.
20. Cates EC et al (2004) Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J Immunol 173:6384-6392.
21. Jacquet A (2011) The role of innate immunity activation in house dust mite allergy. Trends Mol Med 17:604-611. doi:10.1016/j. molmed.2011.05.014.
22. Thomas WR, Smith WA, Hales BJ, Mills KL, O'Brien RM (2002) Characterization and immunobiology of house dust mite allergens. Int Arch Allergy Immunol 129:1-18.
23. Phipps S et al (2009) Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses. Am J Respir Crit Care Med 179:883-893. doi:10.1164/rccm.200806-974OC.
24. Melgert BN et al (2010) Macrophages: regulators of sex differences in asthma? Am J Respir Cell Mol Biol 42:595-603. doi:10.1165/rcmb.2009-0016OC.
25. Melgert BN et al (2005) Female mice are more susceptible to the development of allergic airway inflammation than male mice. Clin Exp Allergy 35:1496-1503. doi:10.1111/j.1365-2222.2005.02362.x.
26. van Rijt LS et al (2004) A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma. J Immunol Methods 288:111-121. doi:10.1016/j. jim.2004.03.004.