Autonomic control of heart rate and QT interval variability influences arrhythmic risk in long QT syndrome type 1

Journal of the American College of Cardiology

Volumn 65, Issue 4, 2015, Pages 367-374

  Porta, Alberto ^a,b   Girardengo, Giulia ^c   Bari, Vlasta ^d   George, Alfred L ^e,f   Brink, Paul A ^g   Goosen, Althea ^g   Crotti, Lia ^c,h   Schwartz, Peter J ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^d IRCCS POLICLINICO SAN DONATO   (Italy)

^e NORTHWESTERN UNIVERSITY   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g STELLENBOSCH UNIVERSITY   (South Africa)

^h INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

autonomic nervous system; beta blocker therapy; cardiovascular control; heart rate variability; QT variability

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL KCNQ1;

ADULT; ARTICLE; BRADYCARDIA; CARDIOVASCULAR RISK; CIRCADIAN RHYTHM; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; GENETIC HETEROGENEITY; GENETIC REGULATION; HEART ARRHYTHMIA; HEART RATE VARIABILITY; HETEROZYGOTE; HIGH RISK PATIENT; HOLTER MONITORING; HUMAN; KCNQ1 GENE; LONG QT SYNDROME 1; LOW RISK PATIENT; MUTATION CARRIER; MUTATIONAL ANALYSIS; NONMUTATION CARRIER; PATHOGENESIS; PHENOTYPE; QT INTERVAL; SLEEP PATTERN; SOUTH AFRICAN; SPECTROSCOPY; SYMPATHETIC TONE; SYMPTOM; TREATMENT RESPONSE; VAGUS NERVE STIMULATION; ADRENERGIC SYSTEM; CASE CONTROL STUDY; ELECTROCARDIOGRAPHY; GENETICS; PATHOPHYSIOLOGY; ROMANO-WARD SYNDROME; VAGUS NERVE;

ADRENERGIC BETA-ANTAGONISTS; ADULT; CASE-CONTROL STUDIES; CIRCADIAN RHYTHM; ELECTROCARDIOGRAPHY; HUMANS; KCNQ1 POTASSIUM CHANNEL; ROMANO-WARD SYNDROME; SYMPATHETIC NERVOUS SYSTEM; VAGUS NERVE;

EID: 84921694268     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.11.015     Document Type: Article

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