RT variability unrelated to heart period and respiration progressively increases during graded head-up tilt

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 5, 2010, Pages

  Porta, Alberto ^a   Tobaldini, Eleonora ^b   Gnecchi Ruscone, Tomaso ^c   Montano, Nicola ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c A MANZONI HOSPITAL   (Italy)

Author keywords

Autonomic nervous system; Modelling; QT measurement; QT variability; QT RR relationship

Indexed keywords

ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BREATHING; ELECTROCARDIOGRAM; FEMALE; HEAD TILTING; HEART HEMODYNAMICS; HEART REPOLARIZATION; HEART RHYTHM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PREDICTOR VARIABLE; PRIORITY JOURNAL; R WAVE; RECORDING; RR INTERVAL; SYMPATHETIC TONE; T WAVE;

ADULT; ALGORITHMS; DATA INTERPRETATION, STATISTICAL; ELECTROCARDIOGRAPHY; FEMALE; FORECASTING; HEART; HEART RATE; HEART VENTRICLES; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; POSTURE; RESPIRATORY MECHANICS; SYMPATHETIC NERVOUS SYSTEM; YOUNG ADULT;

EID: 77951819124     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01206.2009     Document Type: Article

References (40)

1. Akaike H. A new look at the statistical novel identification. IEEE Trans Autom Contr 19: 716-723, 1974.
2. Atiga WL, Calkins H, Lawrence JH, Tomaselli GF, Smith JM, Berger RD. Beat-to-beat repolarization lability identifies patients at risk for sudden cardiac death. J Cardiovasc Electrophysiol 9: 908, 1998. (Pubitemid 28455959)
3. Baselli G, Porta A, Rimoldi O, Pagani M, Cerutti S. Spectral decomposition in multichannel recordings based on multivariate parametric identification. IEEE Trans Biomed Eng 44: 1092-1101, 1997. (Pubitemid 27467387)
4. Baumert M, Lambert GW, Dawood T, Lambert EA, Esler MD, McGrane M, Barton D, Nalivaiko E. QT inteval variability and cardiac norepinephrine spillover in patients with depression and panic disorder. Am J Physiol Heart Circ Physiol 295: H962-H968, 2008.
5. Bazett HC. An analysis of the time-relations of electrocardiograms. Heart 7: 353-370, 1929.
6. Berger RD. QT Interval variability. Is it a measure of autonomic activity? J Am Coll Cardiol 54: 821-852, 2009.
7. Berger RD, Kasper EK, Baughman KL, Marban E, Calkins H, Tomaselli GF. Beat-to-beat QT interval variability: novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy. Circulation 96: 1557-1565, 1997. (Pubitemid 27375352)
8. Bexton RS, Vallin HO, Camm AJ. Diurnal varaition of the QT interval. Influence of the autonomic nervous system. Br Heart J 55: 253-258, 1986.
9. Browne KF, Prystowsky E, Heger JJ, Chilson DA, Zipes DP. Prolongation of the Q-T interval in man during sleep. Am J Cardiol 52: 55-59, 1983. (Pubitemid 13061326)
10. Cappato R, Alboni P, Pedroni P, Gilli G, Antonioli GE. Sympathetic and vagal influences on rate-dependent changes of QT interval in healthy subjects. Am J Cardiol 68: 1188-1193, 1991.
11. Cooke WH, Hoag JB, Crossman AA, Kuusela TA, Tahvanainen KUO, Eckberg DL. Human responses to upright tilt: a window on central autonomic integration. J Physiol 517: 617-628, 1999.
12. Cuomo S, Marciano F, Migaux ML, Finizio F, Pezzella E, Losi MA, Betocchi S. Abnormal QT interval variability in patients with hypertrophic cardiomyopathy. Can syncope be predicted? J Electrocardiol 37: 113-119, 2004. (Pubitemid 38656719)
13. Franz MR, Swerdlow CD, Liem LB, Schaeefer J. Cycle length dependence of human action potential duration in vivo. Effects of single extrastimiuli, sudden sustained rate acceleration and deceleration, and different steady state frequencies. J Clin Invest 82: 972-979, 1988.
14. Furlan R, Porta A, Costa F, Tank J, Baker L, Schiavi R, Robertson D, Malliani A, Moscheda-Garcia R. Oscillatory patterns in sympathetic neural discharge and cardiovascular variables during orthostatic stimulus. Circulation 101: 886-892, 2000. (Pubitemid 30117884)
15. Haigney MC, Zareba W, Gentlesk PJ, Goldstein RE, Illovsky M, McNitt S, Andrews ML, Moss AJ. QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. J Am Coll Cardiol 44: 1481-1487, 2004. (Pubitemid 39303953)
16. Kay SM, Marple SL. Spectrum analysis: a modern perspective. Proc IEEE 69: 1380-1418, 1981.
17. Lau CP, Freeman AR, Fleming SJ, Malik M, Camm AJ, Ward DE. Hysteresis of the ventricular paced QT interval in response to abrupt changes in pacing rate. Cardiovasc Res 22: 67-72, 1988. (Pubitemid 18034779)
18. Lombardi F, Sandrone G, Porta A, Torzillo D, Terranova G, Baselli G, Cerutti S, Malliani A. Spectral analysis of short term R-Tapex interval variability during sinus rhythm and fixed atrial rate. Eur Heart J 17: 769-778, 1996. (Pubitemid 26160786)
19. Lux RL, Ershler PR. Cycle length sequence dependent repolarization dynamics. J Electrocardiol 36: 205-208, 2003.
20. Malik M. Beat-to-beat QT variability and cardiac autonomic regulation. Am J Physiol Heart Circ Physiol 295: H923-H925, 2008.
21. Malik M, Farbom P, Batchvarov V, Hnatkova K, Camm AJ. Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval. Heart 87: 220-228, 2002. (Pubitemid 34177674)
22. Merri M, Benhorin J, Alberti M, Locati E, Moss AJ. Electrocardiographic quantification of ventricular repolarization. Circulation 80: 1301-1308, 1989.
23. Montano N, Gnecchi-Ruscone T, Porta A, Lombardi F, Pagani M, Malliani A. Power spectrum analysis of heart rate variability to assess changes in sympatho-vagal balance during graded orthostatic tilt. Circulation 90: 1826-1831, 1994.
24. Negoescu R, Dinca-Panaitescu S, Filcescu V, Ionescu D, Wolf S. Mental stress enhances the sympatehtic fraction of QT variability in an RR-independent way. Integr Physiol Behav Sci 32: 220-227, 1997. (Pubitemid 127525832)
25. Piccirillo G, Cacciafesta M, Lionetti M, Nocco M, Di Giuseppe V, Moisé A, Naso C, Marigliano V. Influence of age, the autonomic nervous system and anxiety on QT-interval variability. Clin Sci (Lond) 101: 429-438, 2001. (Pubitemid 32929859)
26. Piccirillo G, Magnanti M, Matera S, Di Carlo S, De Laurentis T, Torrini A, Marchitto N, Ricci R, Magrì D. Age and QT variability index during free breathing, controlled breathing and tilt in patients with chronic heart failure and healthy control subjects. Transl Res 142: 72-78, 2006. (Pubitemid 44142354)
27. Piccirillo G, Magrì D, Ogawa M, Song J, Chong VJ, Han S, Joung B, Choi EK, Hwang S, Chen LS, Lin SF, Chen PS. Autonomic nervous system activity measured directly and QT interval variability in normal and pacing-induced tachycarda heart failure dogs. J Am Coll Cardiol 54: 840-850, 2009.
28. Porta A, Baselli G, Caiani E, Malliani A, Lombardi F, Cerutti S. Quantifying electrocardiogram RT-RR variability interactions. Med Biol Eng Comput 36: 27-34, 1998. (Pubitemid 28059649)
29. Porta A, Baselli G, Cerutti C. Implicit and explicit model-based signal processing for the analysis of short-term cardiovascular interactions. Proc IEEE 94: 805-818, 2006.
30. Porta A, Baselli G, Lombardi F, Cerutti S, Antolini R, Del Greco M, Ravelli F, Nollo G. Performance assessment of standard algorithms for dynamic R-T interval measurement: comparison between R-Tapex and R-Tend approach. Med Biol Eng Comput 36: 35-42, 1998. (Pubitemid 28059650)
31. Porta A, Baselli G, Rimoldi O, Malliani A, Pagani M. Assessing baroreflex gain from spontaneous variability in conscious dogs: role of causality and respiration. Am J Physiol Heart Circ Physiol 279: H2558-H2567, 2000.
32. Porta A, Tobaldini E, Guzzetti S, Furlan R, Montano N, Gnecchi-Ruscone T. Assessment of cardiac autonomic modulation during graded head-up tilt by symbolic analysis of heart rate variability. Am J Physiol Heart Circ Physiol 293: H702-H708, 2007. (Pubitemid 47105132)
33. Porta A, Tobaldini E, Magagnin V, Bassani T, Gnecchi-Ruscone T, Montano N. Open loop linear parametric modelling of the QT variability. 31st Annual International Conference of the IEEE EMBS, Minneapolis, MN, Sept. 2-6, 2009, p. 6453-6456.
34. Pueyo E, Smetana P, Caminal P, Bayes de Luna A, Malik M, Laguna P. Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in Amiodarone-trated survivors of acute myocardial infarction. IEEE Trans Biomed Eng 51: 1511-1520, 2004. (Pubitemid 39100224)
35. Segerson NM, Litwin SE, Daccarett M, Scott Wall T, Hamdan MH, Lux RL. Scatter in repolarization timing predicts clinical events in post-myocardial infarction patients. Heart Rhythm 5: 208-214, 2008.
36. Soderstrom T, Stoica P. System Identification. Englewood Cliffs, NJ: Prentice Hall, 1988.
37. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Standard of measurement, physiological interpretation and clinical use. Circulation 93: 1043-1065, 1996.
38. Yamada A, Hayano J, Horie K, Ieda K, Mukai S, Yamada M, Fujinami T. Regulation of QT interval during postural transitory changes in heart rate in normal subjects. Am J Cardiol 71: 996-998, 1993. (Pubitemid 23118077)
39. Yeragani VK, Pohl R, Jampala VC, Balon R, Kay J, Igel G. Effect of posture and isoproterenol on beat-to-beat heart rate and QT variability. Neuropsychobiology 41: 113-123, 2000. (Pubitemid 30172990)
40. Yeragani VK, Pohl R, Jampala VC, Balon R, Ramesh C, Srinivasan K. Increased QT variability in patients with panic disorder and depression. Psychiatry Res 93: 225-235, 2000. (Pubitemid 30175953)