Inhibitory effects of deoxynivalenol on gastric secretion in rats

Journal of Food Protection

Volumn 77, Issue 8, 2014, Pages 1367-1371

  Wang, Yuwei ^a   Wu, Wenda ^a   Wang, Xichun ^b   He, Chenghua ^a   Yue, Hua ^c   Ren, Zhe ^a   Zhang, Haibin ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b ANHUI AGRICULTURAL UNIVERSITY   (China)

^c HENAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN; MYCOTOXIN; TRICHOTHECENE DERIVATIVE; VOMITOXIN;

ANIMAL; DRUG EFFECTS; FEMALE; GENETICS; RAT; SECRETION (PROCESS); STOMACH JUICE; STOMACH MUCOSA; WISTAR RAT;

ANIMALS; FEMALE; GASTRIC JUICE; GASTRIC MUCOSA; GASTRINS; MYCOTOXINS; RATS; RATS, WISTAR; TRICHOTHECENES;

EID: 84921669277     PISSN: 0362028X     EISSN: None     Source Type: Journal    
DOI: 10.4315/0362-028X.JFP-13-470     Document Type: Article

References (43)

1. Anderson, D. E., W. J. Becktel, and F. W. Dahlquist. 1990. pH-induced denaturation of proteins: a single salt bridge contributes 3-5 kcal/mol to the free energy of folding of T4 lysozyme. Biochemistry 29:2403-2408.
2. Arnold, D. L., P. F. McGuire, E. A. Nera, K. F. Karpinski, M. G. Bickis, Z. Z. Zawidzka, S. Fernie, and R. F. Vesonder. 1986. The toxicity of orally administered deoxynivalenol (vomitoxin) in rats and mice. Food Chem. Toxicol. 24:935-941.
3. Avantaggiato, G., R. Havenaar, and A. Visconti. 2004. Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials. Food Chem. Toxicol. 42:817-824.
4. Awad, W. A., J. Bohm, E. Razzazi-Fazeli, K. Ghareeb, and J. Zentek. 2006. Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens. Poult. Sci. 85:974-979.
5. Awad, W. A., J. Bohm, E. Razzazi-Fazeli, and J. Zentek. 2006. Effects of feeding deoxynivalenol contaminated wheat on growth performance, organ weights and histological parameters of the intestine of broiler chickens. J. Anim. Physiol. Anim. Nutr. (Berl.) 90:32-37.
6. Awad, W. A., E. Razzazi-Fazeli, J. Bohm, and J. Zentek. 2007. Influence of deoxynivalenol on the D-glucose transport across the isolated epithelium of different intestinal segments of laying hens. J. Anim. Physiol. Anim. Nutr. (Berl.) 91:175-180.
7. Binder, E., L. Tan, L. Chin, J. Handl, and J. Richard. 2007. Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients. Anim. Feed Sci. Technol. 137:265-282.
8. Blair, D., M. Williams, A. Carr, and S. Kilpatrick. 1965. Effect of L-thyroxine on gastric secretion in the pylorus-ligated rat. Gut 6:343-348.
9. Bo-Linn, G. W., G. R. Davis, D. J. Buddrus, S. G. Morawski, C. Santa Ana, and J. S. Fordtran. 1984. An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium. J. Clin. Invest. 73:640-647.
10. Danicke, S., T. Goyarts, S. Doll, N. Grove, M. Spolders, and G. Flachowsky. 2006. Effects of the Fusarium toxin deoxynivalenol on tissue protein synthesis in pigs. Toxicol. Lett. 165:297-311.
11. Debouck, C., E. Haubruge, P. Bollaerts, D. van Bignoot, Y. Brostaux, A. Werry, and M. Rooze. 2001. Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice. Int. Orthop. 25:194-198.
12. De Walle, J. V., T. Sergent, N. Piront, O. Toussaint, Y. J. Schneider, and Y. Larondelle. 2010. Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis. Toxicol. Appl. Pharmacol. 245:291-298.
13. Ezekiel, C. N., B. Warth, I. M. Ogara, W. A. Abia, V. C. Ezekiel, J. Atehnkeng, M. Sulyok, P. C. Turner, G. O. Tayo, R. Krska, and R. Bandyopadhyay. 2014. Mycotoxin exposure in rural residents in northern Nigeria: a pilot study using multi-urinary biomarkers. Environ. Int. 66:138-145.
14. Fioramonti, J., C. Dupuy, J. Dupuy, and L. Bueno. 1993. The mycotoxin, deoxynivalenol, delays gastric emptying through serotonin-3 receptors in rodents. J. Pharmacol. Exp. Ther. 266:1255-1260.
15. Forsyth, D. M., T. Yoshizawa, N. Morooka, and J. Tuite. 1977. Emetic and refusal activity of deoxynivalenol to swine. Appl. Environ. Microbiol. 34:547-552.
16. González-Osnaya, L., C. Cortés, J. M. Soriano, J. C. Moltó, and J. Mañes. 2011. Occurrence of deoxynivalenol and T-2 toxin in bread and pasta commercialised in Spain. Food Chem. 124:156-161.
17. Goossens, J., F. Pasmans, E. Verbrugghe, V. Vandenbroucke, S. De Baere, E. Meyer, F. Haesebrouck, P. De Backer, and S. Croubels. 2012. Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin. BMC Vet. Res. 8:245.
18. Håkanson, R., J. Hedenbro, G. Liedberg, F. Sundler, and S. Vallgren. 1980. Mechanisms of gastric acid secretion after pylorus and oesophagus ligation in the rat. J. Physiol. 305:139-149.
19. Harboe, M., P. M. Andersen, B. Foltmann, J. Kay, and B. Kassell. 1974. The activation of bovine pepsinogen sequence of the peptides released, identification of a pepsin inhibitor. J. Biol. Chem. 249:4487-4494.
20. Jaksic, S., B. Abramovic, I. Jajic, M. Z. Balos, Z. Mihaljev, V. Despotovic, and D. Sojic. 2012. Co-occurrence of fumonisins and deoxynivalenol in wheat and maize harvested in Serbia. Bull. Environ. Contam. Toxicol. 89:615-619.
21. Ji, F., J. Xu, X. Liu, X. Yin, and J. Shi. 2014. Natural occurrence of deoxynivalenol and zearalenone in wheat from Jiangsu province, China. Food Chem. 157:393-397.
22. Kopin, A. S., Y. M. Lee, E. W. McBride, L. J. Miller, M. Lu, H. Y. Lin, L. F. Kolakowski, Jr., and M. Beinborn. 1992. Expression cloning and characterization of the canine parietal cell gastrin receptor. Proc. Natl. Acad. Sci. USA 89:3605-3609.
23. Kurasawa, T., Y. Chikaraishi, A. Naito, Y. Toyoda, and Y. Notsu. 2005. Effect of humulus lupulus on gastric secretion in a rat pylorus-ligated model. Biol. Pharm. Bull. 28:353-357.
24. Lindström, E.,D.Chen, P. Norlén, K. Andersson, and R.Håkanson. 2001. Control of gastric acid secretion: the gastrin-ECL cell-parietal cell axis. Comp. Biochem. Physiol. Part A: Mol. Integr. Physiol. 128:503-511.
25. Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 -ΔΔCT method. Methods 25:402-408.
26. Lowry, O., N. Rosebrough, A. Farr, and R. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265.
27. Maresca, M., R. Mahfoud, N. Garmy, and J. Fantini. 2002. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. J. Nutr. 132:2723-2731.
28. Matumba, L., C. Van Poucke, T. Biswick, M.Monjerezi, J. Mwatseteza, and S. De Saeger. 2014. A limited survey of mycotoxins in traditional maize based opaque beers in Malawi. Food Control 36:253-256.
29. McPhie, P. 1972. A spectrophotometric investigation of the pepsinogen-pepsin conversion. J. Biol. Chem. 247:4277-4281.
30. Noakes, T. D., N. J. Rehrer, and R. J. Maughan. 1991. The importance of volume in regulating gastric emptying. Med. Sci. Sports Exerc. 23:307-313.
31. O'Neill, K., A. P. Damoglou, and M. F. Patterson. 1993. The stability of deoxynivalenol and 3-acetyl deoxynivalenol to gamma irradiation. Food Addit. Contam. 10:209-215.
32. Pestka, J. J. 2007. Deoxynivalenol: toxicity, mechanisms and animal health risks. Anim. Feed Sci. Technol. 137:283-298.
33. Pestka, J. J., and C. J. Amuzie. 2008. Tissue distribution and proinflammatory cytokine gene expression following acute oral exposure to deoxynivalenol: comparison of weanling and adult mice. Food Chem. Toxicol. 46:2826-2831.
34. Pestka, J. J., Z. Islam, and C. J. Amuzie. 2008. Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse. Toxicol. Lett. 178:83-87.
35. Pestka, J. J., and A. T. Smolinski. 2005. Deoxynivalenol: toxicology and potential effects on humans. J. Toxicol. Environ. Health B Crit. Rev. 8:39-69.
36. Piper, D., and B. H. Fenton. 1965. pH stability and activity curves of pepsin with special reference to their clinical importance. Gut 6:506-508.
37. Sergeev, I. N., L. V. Kravchenko, N. M. Piliia, A. B. Batukhanov, V. S. Sobolev, E. E. Kuz'mina, L. M. Iakushina, V. B. Spirichev, and V. A. Tutel'ian. 1990. [The effect of the trichothecene mycotoxin deoxynivalenol (vomitoxin) on calcium homeostasis, vitamin D metabolism and receptors in rats]. Vopr. Med. Khim. 36:26-29.
38. Wolfe, M. M., and C. C. Tseng. 1993. The gastrin (or is it CCK-B?) receptor on the parietal cell is cloned. Gastroenterology 104:1876-1878.
39. Wolf-Hall, C. E., M. A. Hanna, and L. B. Bullerman. 1999. Stability of deoxynivalenol in heat-treated foods. J. Food Prot. 62:962-964.
40. Yoshida, M., and T. Nakajima. 2010. Deoxynivalenol and nivalenol accumulation in wheat infected with Fusarium graminearum during grain development. Phytopathology 100:763-773.
41. Zhao, H., Y. Wang, Y. Zou, and M. Zhao. 2013. Natural occurrence of deoxynivalenol in soy sauces consumed in China. Food Control 29:71-75.
42. Zhu, H., C. Hart, D. Sales, and N. Roberts. 2006. Bacterial killing in gastric juice - effect of pH and pepsin on Escherichia coli and Helicobacter pylori. J. Med. Microbiol. 55:1265-1270.
43. Zielonka, L., M. Wisniewska, M. Gajecka, K. Obremski, and M. Gajecki. 2009. Influence of low doses of deoxynivalenol on histopathology of selected organs of pigs. Pol. J. Vet. Sci. 12:89-95.