Emotion dysregulation mediates the relationship between lifetime cumulative adversity and depressive symptomatology

Journal of Psychiatric Research

Volumn 61, Issue , 2015, Pages 89-96

  Abravanel, Benjamin T ^a   Sinha, Rajita ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adversity; Cumulative stress; Depression; Emotion regulation; Mediation

Indexed keywords

ADULT; ARTICLE; CENTER FOR EPIDEMIOLOGIC STUDIES DEPRESSION SCALE; CONTROLLED STUDY; CORRELATIONAL STUDY; CUMULATIVE ADVERSITY INVENTORY; DEPRESSION; DEPRESSION ASSESSMENT; DIFFICULTIES IN EMOTION REGULATION SCALE; DISEASE ASSOCIATION; EMOTION ASSESSMENT; EMOTION DYSREGULATION; EMOTIONAL DISORDER; EMOTIONALITY; FEMALE; HUMAN; LIFE STRESS; LIFETIME CUMULATIVE ADVERSITY; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; STRESS ASSESMENT; ADAPTIVE BEHAVIOR; EMOTION; HUMAN RELATION; LIFE EVENT; PERCEPTION; PERSONALITY TEST; PSYCHOLOGY; RISK FACTOR; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADAPTATION, PSYCHOLOGICAL; ADULT; DEPRESSION; EMOTIONS; FEMALE; HUMANS; INTERPERSONAL RELATIONS; LIFE CHANGE EVENTS; MALE; PERSONALITY INVENTORY; RISK FACTORS; SOCIAL PERCEPTION; YOUNG ADULT;

EID: 84921598402     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2014.11.012     Document Type: Article

References (76)

1. Aldao A., Nolen-Hoeksema S., Schweizer S. Emotion-regulation strategies across psychopathology: a meta-analytic review. Clin Psychol Rev 2010, 10:217-237.
2. Ansell E.B., Rando K., Tuit K., Guarnaccia J., Sinha R. Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions. Biol Psychiat 2012, 72:57-64.
3. Bandura A., Caprara G.V., Barbaranelli C., Gerbino M., Pastorelli C. Role of affective self-regulatory efficacy in diverse spheres of psychosocial functioning. Child Dev 2003, 74:769-782.
4. Bargh J.A., Williams L.E. On the nonconscious of emotion regulation. Handbook of emotion regulation 2007, 429-445. Guilford Press, New York. J.J. Gross (Ed.).
5. Baron R.M., Kenney D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. JPers Soc Psychol 1986, 51:1173-1182.
6. Benjet C., Borges G., Medina-Mora M.E. Chronic childhood adversity and onset of psychopathology during three life stages: childhood, adolescence and adulthood. JPsychiatr Res 2010, 44:732-740.
7. Berking M., Wupperman P., Reichhardt A., Pejic T., Dippel A., Znoj H. Emotion-regulation skills as a treatment target in psychotherapy. Behav Res Ther 2008, 46:1230-1237.
8. Berking M., Ebert D., Cuijpers P., Hofmann S.G. Emotion regulation skills training enhances the efficacy of inpatient cognitive behavioral therapy for major depressive disorder: a randomized controlled trial. Psychother Psychosom 2013, 82:234-245.
9. Bradley B., DeFife J.A., Guarnaccia C., Phifer J., Fani N., Ressler K.J., et al. Emotion dysregulation and negative affect: association with psychiatric symptoms. JClin Psychiatry 2011, 72:685-691.
10. Bromet E., Andrade L.H., Hwang I., Sampson N.A., Alonso J., de Girolamo G., et al. Cross-national epidemiology of DSM-IV major depressive episode. BMC Psychiatry 2011, 9:90.
11. Campbell-Sills L., Barlow D.H. Incorporating emotion regulation intro conceptualizations and treatments of anxiety and mood disorders. Handbook of emotion regulation 2007, 542-559. Guilford Press, New York. J.J. Gross (Ed.).
12. Caprara G.V., Gerbino M., Paciello M., Di Giunta L., Pastorelli C. Counteracting depression and delinquency in late adolescence: the role of regulatory emotional and interpersonal self-efficacy beliefs. Eur Psychol 2010, 15:34-48.
13. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301:386-389.
14. Coates A.A., Messman-Moore T.L. Astructural model of mechanisms predicting depressive symptoms in women following childhood psychological maltreatment. Child Abuse Negl 2014, 38:103-113.
15. Corcoran K.M., Farb N., Anderson A., Segal Z.V. Mindfulness and emotion regulation: outcomes and possible mediating mechanisms. Emotion regulation and psychopathology: a transdiagnostic approach to etiology and treatment 2009, 339-355. Guilford Press, New York. A.M. Kring, D.M. Sloan (Eds.).
16. Crow T., Cross D., Powers A., Bradley B. Emotion dysregulation as a mediator between childhood emotional abuse and current depression in a low-income African American sample. Child Abuse Negl 2014, 38:1590-1598.
17. Cuijpers P., Smit F. Subthreshold depression as a risk indicator for major depressive disorder: a systematic review of prospective studies. Acta Psychiat Scand 2004, 109:325-331.
18. Cuijpers P., Smit F., Van Straten A. Psychological treatments for subthreshold depression: a meta-analytic review. Acta Psychiat Scand 2007, 115:434-441.
19. Davidson R.J., Pizzagalli D., Nitschke J.B., Putnam K. Depression: perspectives from affective neuroscience. Ann Rev Psychol 2002, 53:545-574.
20. Devins G.M., Orme C.M., Costello C.G., Binik Y.M., Frizzell B., Stam H.J., et al. Measuring depressive symptoms in illness populations: psychometric properties of the Center for Epidemiologic Studies Depression (CES-D) scale. Psychol Health 1988, 2:139-156.
21. Dohrenwend B.P. Inventorying stressful life events as risk factors for psychopathology: toward resolution of the problem of intracategory variability. Psychol Bull 2006, 132:477-495.
22. Dvir Y., Ford J.D., Hill M., Frazier J.A. Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities. Harv Rev Psychiatry 2014, 22:149-161.
23. Enns M.W., Cox B.J., Borger S.C. Correlates of analogue and clinical depression: a further test of the phenomenological continuity hypothesis. JAffect Disord 2001, 66:175-183.
24. Fairholme C.P., Boisseau C.L., Ellard K.K., Ehrenreich J.T., Barlow D.H. Emotions, emotion regulation, and psychological treatment: a unified perspective. Emotion regulation and psychopathology: a transdiagnostic approach to etiology and treatment 2009, 283-309. Guilford Press, New York. A.M. Kring, D.M. Sloan (Eds.).
25. First M.B., Spitzer R.L., Gibbons M., Williams J.B.W. Structured clinical interview for DSM-IV axis I disorders - Patient version (SCID-I/P) 1996, New York State Psychiatric Institute, New York.
26. Flett G.L., Vredenburg K., Krames L. The continuity of depression in clinical and nonclinical samples. Psychol Bull 1997, 121:395-416.
27. Garrison C.Z., Addy C.L., Jackson K.L., McKeown R.E., Waller J.L. The CES-D as a screen for depression and other psychiatric disorders in adolescents. JAm Acad Child Psychiatry 1991, 30:636-641.
28. Gayman M.D., Turner R.J., Cui M. Physical limitations and depressive symptoms: exploring the nature of the association. JGerontol B Psychol Sci Soc Sci 2008, 63:S219-S228.
29. Goldsmith R.E., Chesney S.A., Heath N.M., Barlow M.R. Emotion regulation difficulties mediate associations between betrayal trauma and symptoms of posttraumatic stress, depression, and anxiety. JTrauma Stress 2013, 26:376-384.
30. Grant K.E., Compas B.E., Thurm A.E., McMahon S.D., Gipson P.Y., Campbell A.J., et al. Stressors and child and adolescent psychopathology: evidence of moderating and mediating effects. Clin Psychol Rev 2006, 26:257-283.
31. Gratz K.L., Roemer L. Multidimensional assessment of emotion regulation and dysregulation: development, factor structure, and initial validation of the difficulties in emotion regulation scale. JPsychopathol Behav 2004, 26:41-54.
32. Gratz K.L., Tull M.T. Emotion regulation as a mechanism of change in acceptance- and mindfulness-based treatments. Assessing mindfulness and acceptance processes in clients: Illuminating the theory and practice of change 2010, 107-134. New Harbinger Publications, Oakland, CA. R.A. Baer (Ed.).
33. Gross J.J. The emerging field of emotion regulation: an integrative review. Rev Gen Psychol 1998, 2:271-299.
34. Gross J.J., Munoz R.F. Emotion regulation and mental health. Clin Psychol-Sci Pr 1995, 2:151-164.
35. Hammen C. Stress and depression. Annu Rev Clin Psychol 2005, 1:293-319.
36. Hayes A.F. Introduction to mediation, moderation, and conditional process analysis: a regression-based approach 2013, Guilford Press, New York.
37. Hopp H., Troy A.S., Mauss I.B. The unconscious pursuit of emotion regulation: Implications for psychological health. Cogn Emot 2011, 25:532-545.
38. Kessler R.C. The effects of stressful life events on depression. Annu Rev Psychol 1997, 48:191-214.
39. Kessler R.C., Zhao S., Blazer D.G., Swartz M. Prevalence, correlates, and course of minor depression and major depression in the National Comorbidity Survey. JAffect Disord 1997, 45:19-30.
40. Kim P., Evans G.W., Angstadt M., Ho S.S., Sripada C.S., Swain J.E., et al. Effects of childhood poverty and chronic stress on emotion regulatory brain function in adulthood. Proc Natl Acad Sci USA 2013, 110:18442-18447.
41. Kovacs M., Lopez-Duran N.L. Contextual emotion regulation therapy: a developmentally-based intervention for pediatric depression. Child Adul Psych Cl 2012, 21:327-342.
42. Lewinsohn P.M., Solomon A., Seeley J.R., Zeiss A. Clinical implications of "subthreshold" depressive symptoms. JAbnorm Psychol 2000, 109:345-351.
43. Mabunda M., Idemudia E.S. Cumulative adversities and mental health of employees in workplace settings in Gauteng Province, South Africa. JSoc Sci 2012, 33:189-199.
44. Maddux J.E., Meier L.J. Self efficacy and depression. Self-efficacy, adjustment, and adaptation: theory, research, and application 1995, 143-169. Plenum Press, New York. J.E. Maddux (Ed.).
45. McEwen B.S. Protection and damage from acute and chronic stress: allostatis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann NY Acad Sci 2004, 1032:1-7.
46. McEwen B.S. Brain on stress: how the social environment gets under the skin. Proc Natl Acad Sci USA 2012, 109:17180-17185.
47. McLaughlin K.A., Hatzenbuehler M.L. Stressful life events, anxiety sensitivity, and internalizing symptoms in adolescents. JAbnorm Psychol 2009, 118:659-669.
48. Mennin D.S., Fresco D.M. Emotion regulation as a framework for understanding and treating psychopathology. Emotion regulation and psychopathology: a transdiagnostic approach to etiology and treatment 2009, 256-379. Guilford Press, New York. A.M. Kring, D.M. Sloan (Eds.).
49. Mennin D.S., Holoway R.M., Fresco D.M., Moore M.T., Heimberg R.G. Delineating components of emotion and its dysregulation in anxiety and mood psychopathology. Behav Ther 2007, 38:284-302.
50. Moriya J., Takahashi Y. Depression and interpersonal stress: the mediating role of emotion regulation. Motiv Emot 2013, 37:600-608.
51. Ochsner K.N., Gross J.J. The cognitive control of emotion. Trends Cogn Sci 2005, 9:242-249.
52. Ortega V. Specificity of age differences in emotion regulation. Aging Ment Health 2009, 13:818-826.
53. Preacher K.J., Hayes A.F. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods 2008, 40:879-891.
54. Preacher K.J., Kelley K. Effect size measures for mediation models: quantitative strategies for communicating indirect effects. Psychol Methods 2011, 16:93-115.
55. Radloff L.S. The CES-D Scale: a self-report depression scale for research in the general population. Appl Psych Meas 1977, 1:385-401.
56. Raio C.M., Orederu T.A., Palazzolo L., Shurick A.A., Phelps E.A. Cognitive emotion regulation fails the stress test. Proc Natl Acad Sci USA 2013, 110:15139-15144.
57. Repetti R.L., Taylor S.E., Seeman T.E. Risky families: family social environments and the mental and physical health of offspring. Psychol Bull 2002, 128:330.
58. Rodriguez M.R., Nuevo R., Chatterji S., Ayuso Mateos J.L. Definitions and factors associated with subthreshold depressive conditions: a systematic review. BMC Psychiatry 2012, 12:181.
59. Rottenberg J., Gross J.J. When emotion goes wrong: realizing the promise of affective science. Clin Psychol-Sci Pr 2003, 10:227-232.
60. Scott K.M., Von Korff M., Alonso J., Angermeyer M.C., Benjet C., Bruffaerts R., et al. Childhood adversity, early-onset depressive/anxiety disorders, and adult-onset asthma. Psychosom Med 2008, 70:1035-1043.
61. Seligman M.E.P., Cook L. Learned helplessness and depression. Readings in contemporary psychology 1978, 270-282. Trillas, Mexico City. G.E. Finley, G. Marin (Eds.).
62. Seo D., Tsou K.A., Ansell E.B., Potenza M.N., Sinha R. Cumulative adversity sensitizes neural response to acute stress: association with health symptoms. Neuropsychopharmacol 2014, 39:670-680.
63. Shallcross A.J., Troy A.S., Boland M., Mauss I.B. Let it be: accepting negative emotional experiences predicts decreased negative affect and depressive symptoms. Behav Res Ther 2010, 48:921-929.
64. Shrira A. The effect of lifetime cumulative adversity on change and chronicity in depressive symptoms and quality of life in older adults. Int Psychogeriatr 2012, 24:1988-1997.
65. Sinha R. How does stress increase risk of drug abuse and relapse?. Psychopharmacology 2001, 158:343-359.
66. Solomon A., Haaga D.A., Arnow B.A. Is clinical depression distinct from subthreshold depressive symptoms? A review of the continuity issue in depression research. JNerv Ment Dis 2001, 189:498-506.
67. Stevens N.R., Gerhart J., Goldsmith R.E., Heath N.M., Chesney S.A., Hobfoll S.E. Emotion regulation difficulties, low social support, and interpersonal violence mediate the link between childhood abuse and posttraumatic stress symptoms. Behav Ther 2013, 44:152-161.
68. Syzdek M.R., Addis M.E., Martell C.R. Working with emotion and emotion regulation in behavioral activation therapy for depressed mood. Emotion regulation and psychopathology: a transdiagnostic approach to etiology and treatment 2009, 405-426. Guilford Press, New York. A.M. Kring, D.M. Sloan (Eds.).
69. Tafet G.E., Bernardini R. Psychoneuroendocrinological links between chronic stress and depression. Prog Neuropsychopharmacol Biol Psychiatry 2003, 27:893-903.
70. Thompson R.A. Emotion regulation: a theme in search of definition. Monogr Soc Res Child 1994, 59:25-52.
71. Turner R.J., Lloyd D.A. Lifetime traumas and mental health: the significance of cumulative adversity. JHealth Soc Behav 1995, 36:360-376.
72. Turner R.J., Lloyd D.A. Stress burden and the lifetime incidence of psychiatric disorder in young adults: racial and ethnic contrasts. Arch Gen Psychiatry 2004, 61:481-488.
73. Turner R.J., Wheaton B., Lloyd D.A. The epidemiology of social stress. Am Sociol Rev 1995, 60:104-125.
74. van der Veek S.M.C., Kraaij V., Garnefski N. Cognitive coping strategies and stress in parents of children with down syndrome: a prospective study. Intellect Dev Disabil 2009, 47:295-306.
75. Watson D. Rethinking the mood and anxiety disorders: a quantitative hierarchical model for DSM-V. JAbnorm Psychol 2005, 114:522-536.
76. Weissman M.M., Sholomskas D., Pottenger M., Prusoff B.A., Locke B.Z. Assessing depressive symptoms in five psychiatric populations: a validation study. Am J Epidemiol 1977, 106:203-214.