Lymphocytic mitochondrial aconitase activity is reduced in Alzheimer's disease and mild cognitive impairment

Journal of Alzheimer's Disease

Volumn 44, Issue 2, 2015, Pages 649-660

  Mangialasche, Francesca ^a,b   Baglioni, Mauro ^a   Cecchetti, Roberta ^a   Kivipelto, Miia ^b   Ruggiero, Carmelinda ^a   Piobbico, Danilo ^a   Kussmaul, Lothar ^c   Monastero, Roberto ^d   Brancorsini, Stefano ^a   Mecocci, Patrizia ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^d UNIVERSITY OF PALERMO   (Italy)

Author keywords

Aconitase (aconitate hydratase); Alzheimer disease; antioxidants; free radicals; lymphocyte; mild cognitive impairment; mitochondria; oxidative stress; reactive nitrogen species; reactive oxygen species

Indexed keywords

ACONITATE HYDRATASE; ALPHA TOCOPHEROL; ASCORBIC ACID; FREE RADICAL; MITOCHONDRIAL PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; RETINOL; URIC ACID; ACO2 PROTEIN, HUMAN; BIOLOGICAL MARKER; MESSENGER RNA;

ADULT; AGED; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN MITOCHONDRION; CITRIC ACID CYCLE; CLINICAL ARTICLE; CLINICAL DEMENTIA RATING; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; FEMALE; GERIATRIC DEPRESSION SCALE; HAMILTON ANXIETY SCALE; HUMAN; IN VITRO STUDY; LYMPHOCYTE; MALE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NITROSATIVE STRESS; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; URIC ACID BLOOD LEVEL; VITAMIN BLOOD LEVEL; BLOOD; MENTAL HEALTH; METABOLISM; MITOCHONDRION; POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACONITATE HYDRATASE; AGED; ALZHEIMER DISEASE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; DISEASE PROGRESSION; FEMALE; FREE RADICALS; HUMANS; LYMPHOCYTES; MALE; MENTAL STATUS SCHEDULE; MILD COGNITIVE IMPAIRMENT; MITOCHONDRIA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; VITAMIN E;

EID: 84921535131     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-142052     Document Type: Article

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