Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity

NeuroToxicology

Volumn 46, Issue , 2015, Pages 53-59

  Mohan, Shekher ^a   Narumiya, Shuh ^b   Doré, Sylvain ^a,c  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

Heme; Hemoglobin; Inflammation; Neurons; Protein kinase A

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; BUTAPROST; CALCEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; HEMIN; LACTATE DEHYDROGENASE; PROSTAGLANDIN E RECEPTOR 2; 8-((4-CHLOROPHENYL)THIO)CYCLIC-3',5'-AMP; AMINO ACID RECEPTOR STIMULATING AGENT; GLUTAMIC ACID; IMMUNOLOGICAL ADJUVANT; NEUROPROTECTIVE AGENT; NUCLEOTIDE; PROSTAGLANDIN E1;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOCHEMISTRY; CYTOTOXICITY; FEMALE; IN VITRO STUDY; MALE; MITOCHONDRION; MOUSE; NERVE CELL CULTURE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WILD TYPE; AGONISTS; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; BRAIN CORTEX; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL;

MUS;

ADJUVANTS, IMMUNOLOGIC; ALPROSTADIL; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; CELL SURVIVAL; CEREBRAL CORTEX; COLFORSIN; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; HEMIN; L-LACTATE DEHYDROGENASE; MICE; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; THIONUCLEOTIDES;

EID: 84921510765     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.10.012     Document Type: Article

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