Dual contradictory roles of cAMP signaling pathways in hydroxyl radical production in the rat striatum

Free Radical Biology and Medicine

Volumn 52, Issue 6, 2012, Pages 1086-1092

  Hara, Shuichi ^a   Kobayashi, Masamune ^a   Kuriiwa, Fumi ^a   Mukai, Toshiji ^b   Mizukami, Hajime ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

cAMP; Carbon monoxide poisoning; Epac; Hydroxyl radical; PKA; Rat striatum

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; 8 BROMO CYCLIC AMP; ADENYLATE CYCLASE; BUCLADESINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; HYDROXYL RADICAL; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBON MONOXIDE INTOXICATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVATION; ENZYME INHIBITION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; BIOMIMETIC MATERIALS; CARBON MONOXIDE; CARBON MONOXIDE POISONING; CORPUS STRIATUM; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FORSKOLIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HYDROXYBENZOATES; HYDROXYL RADICAL; ISOQUINOLINES; MALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SULFONAMIDES;

RATTUS;

EID: 84857233993     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.01.002     Document Type: Article

References (46)

1. J.A. Beavo, and L.L. Brunton Cyclic nucleotide research-still expanding after half a century Nat. Rev. Mol. Cell Biol. 3 2002 710 718
2. A.J. Murray Pharmacological PKA inhibition: all may not be what it seems Sci. Signal. 1 2008 re4
3. F. Schwede, E. Maronde, H. Genieser, and B. Jastorff Cyclic nucleotide analogs as biochemical tools and prospective drugs Pharmacol. Ther. 87 2000 199 226
4. M. Biel Cyclic nucleotide-regulated cation channels J. Biol. Chem. 284 2009 9017 9021
5. G.C. Palmer Cyclic nucleotides in stroke and related cerebrovascular disorders Life Sci. 36 1985 1995 2006
6. K. Tanaka Alteration of second messengers during acute cerebral ischemia-adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP response element binding protein Prog. Neurobiol. 65 2001 173 207
7. H.T. Lee, Y.C. Chang, L.Y. Wang, S.T. Wang, C.C. Huang, and C.J. Ho cAMP response element-binding protein activation in ligation preconditioning in neonatal brain Ann. Neurol. 56 2004 611 623
8. J.M. Choi, H.K. Shin, K.Y. Kim, J.H. Lee, and K.W. Hong Neuroprotective effect of cilostazol against focal cerebral ischemia via antiapoptotic action in rats J. Pharmacol. Exp. Ther. 300 2002 787 793
9. N. Miyamoto, R. Tanaka, T. Shimosawa, Y. Yatomi, T. Fujita, N. Hattori, and T. Urabe Protein kinase A-dependent suppression of reactive oxygen species in transient focal ischemia in adrenomedullin-deficient mice J. Cereb. Blood Flow Metab. 29 2009 1769 1779
10. T. Sasaki, K. Kitagawa, E. Omura-Matsuoka, K. Todo, Y. Terasaki, S. Sugiura, J. Hatazawa, Y. Yagita, and M. Hori The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia Stroke 38 2007 1597 1605
11. E. Carrasco, P. Werner, and D. Casper Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress Neurosci. Lett. 441 2008 44 49
12. E.J. Kim, K.J. Kwon, J.Y. Park, S.H. Lee, C.H. Moon, and E.J. Baik Neuroprotective effects of prostaglandin E2 or cAMP against microglial and neuronal free radical mediated toxicity associated with inflammation J. Neurosci. Res. 70 2002 97 107
13. R. Prado, R. Busto, and M.Y. Globus Ischemia-induced changes in extracellular levels of striatal cyclic AMP: role of dopamine neurotransmission J. Neurochem. 59 1992 1581 1584
14. Z.J. Yang, M. Torbey, X. Li, J. Bernardy, W.C. Golden, L.J. Martin, and R.C. Koehler Dopamine receptor modulation of hypoxic-ischemic neuronal injury in striatum of newborn piglets J. Cereb. Blood Flow Metab. 27 2007 1339 1351
15. S. Amadio, N. D'Ambrosi, M.L. Trincavelli, D. Tuscano, G. Sancesario, G. Bernadi, C. Martini, and C. Volonté Differences in the neurotoxicity profile induced by ATP and ATPgS in cultured cerebellar granule neurons Neurochem. Int. 47 2005 334 342
16. Y.C. Chang, C.C. Huang, P.L. Hung, and H.M. Huang Rolipram, a phosphodiesterase type IV inhibitor, exacerbates periventricular white matter lesions in rat pups Pediatr. Res. 64 2008 234 239
17. M.Y. Globus, R. Busto, B. Lin, H. Schnippering, and M.D. Ginsberg Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation J. Neurochem. 65 1995 1250 1256
18. H.Y. Kil, J. Zhang, and C.A. Piantadosi Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats J. Cereb. Blood Flow Metab. 16 1996 100 106
19. C. Themann, P. Teismann, K. Kuschinsky, and B. Ferger Comparison of two independent aromatic hydroxylation assays in combination with intracerebral microdialysis to determine hydroxyl free radicals J. Neurosci. Methods 108 2001 57 64
20. X.G. Xia, N. Schmidt, P. Teismann, B. Ferger, and J.B. Schulz Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation J. Neurochem. 79 2001 63 70
21. E. Lancelot, M.L. Revaud, R.G. Boulu, M. Plotkine, and J. Callebert A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate Brain Res. 809 1998 294 296
22. P. Teismann, and B. Ferger The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro Brain Res. Protoc. 5 2000 204 210
23. M. Ingelman-Sundberg, H. Kaur, Y. Terelius, J.O. Persson, and B. Halliwell Hydroxylation of salicylate by microsomal fractions and cytochrome P-450: lack of production of 2,3-dihydroxybenzoate unless hydroxyl radical formation is permitted Biochem. J. 276 1991 753 757
24. S. Hara, H. Mizukami, K. Kurosaki, F. Kuriiwa, and T. Mukai Existence of a threshold for hydroxyl radical generation independent of hypoxia in rat striatum during carbon monoxide poisoning Arch. Toxicol. 85 2011 1091 1099
25. 11-like receptors in rat striatum due to severe, but not moderate, carbon monoxide poisoning Toxicology 288 2011 49 55
26. A. Laurenza, Y. Khandelwal, N.J. De Souza, R.H. Rupp, H. Metzger, and K.B. Seamon Stimulation of adenylate cyclase by water-soluble analogues of forskolin Mol. Pharmacol. 32 1987 133 139
27. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 1998 Academic Press San Diego
28. S. Hara, H. Mizukami, T. Mukai, K. Kurosaki, F. Kuriiwa, and T. Endo Involvement of extracellular ascorbate and iron in hydroxyl radical generation in rat striatum in carbon monoxide poisoning Toxicology 264 2009 69 73
29. A. Lochner, and J.A. Moolman The many faces of H89: a review Cardiovasc. Drug Rev. 24 2006 261 274
30. H. Poppe, S.D. Rybalkin, H. Rehmann, T.R. Hinds, X.B. Tang, A.E. Christensen, F. Schwede, H.G. Genieser, J.L. Bos, S.O. Doskeland, J.A. Beavo, and E. Butt Cyclic nucleotide analogs as probes of signaling pathways Nat. Methods 5 2008 277 278
31. H. Rehmann, F. Schwede, S.O. Døskeland, A. Wittinghofer, and J.L. Bos Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac J. Biol. Chem. 278 2003 38548 38556
32. S.J. Wang, and T.S. Sihra Opposing facilitatory and inhibitory modulation of glutamate release elicited by cAMP production in cerebrocortical nerve terminals (synaptosomes) Neuropharmacology 44 2003 686 697
33. S. Dolan, and A.M. Nolan Biphasic modulation of nociceptive processing by the cyclic AMP-protein kinase A signalling pathway in sheep spinal cord Neurosci. Lett. 309 2001 157 160
34. B. Yusta, J. Ortiz-Caro, A. Pascual, and A. Aranda Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate J. Neurochem. 51 1988 1808 1818
35. P.J. England, and M. Shahid Effects of forskolin on contractile responses and protein phosphorylation in the isolated perfused rat heart Biochem. J. 246 1987 687 695
36. S.F. Steinberg, and L.L. Brunton Compartmentation of G protein-coupled signaling pathways in cardiac myocytes Annu. Rev. Pharmacol. Toxicol. 41 2001 751 773
37. D.M.F. Cooper, and A.J. Crossthwaite Higher-order organization and regulation of adenylyl cyclases Trends Pharmacol. Sci. 27 2006 426 431
38. S. Suzuki, U. Yokoyama, T. Abe, H. Kiyonari, N. Yamashita, Y. Kato, R. Kurotani, M. Sato, S. Okumura, and Y. Ishikawa Differential roles of Epac in regulating cell death in neuronal and myocardial cells J. Biol. Chem. 285 2010 24248 24259
39. M.B. Bogdanov, R.J. Ferrante, S. Kuemmerle, P. Klivenyi, and M.F. Beal Increased vulnerability to 3-nitropropionic acid in an animal model of Huntington's disease J. Neurochem. 71 1998 2642 2644
40. R. Dohovics, R. Janáky, V. Varga, A. Hermann, P. Saransaari, and S.S. Oja Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes Neurochem. Int. 42 2003 1 7
41. L.E. Chavez-Noriega, and C.F. Stevens Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices J. Neurosci. 14 1994 310 317
42. M.G. Weisskopf, P.E. Castillo, R.A. Zalutsky, and R.A. Nicoll Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP Science 265 1994 1878 1882
43. I. Gekel, and E. Neher Application of an Epac activator enhances neurotransmitter release at excitatory central synapses J. Neurosci. 28 2008 7991 8002
44. S. Hara, T. Mukai, K. Kurosaki, F. Kuriiwa, and T. Endo Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis Brain Res. 1016 2004 281 284
45. Y. Fu, F. He, S. Zhang, J. Huang, J. Zhang, and X. Jiao 3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum Neurotoxicol. Teratol. 17 1995 333 339
46. P. Nasr, T. Carbery, and J.W. Geddes N-methyl-D-aspartate receptor antagonists have variable affect in 3-nitropropionic acid toxicity Neurochem. Res. 34 2009 490 498