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Volumn 1849, Issue 3, 2015, Pages 247-256

Epigenetic regulation of p14ARF and p16INK4A expression in cutaneous and uveal melanoma

Author keywords

Epi drug; Histone deacetylation; Human melanoma; P14ARF; P16INK4A; Promoter methylation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DECITABINE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HISTONE H3; HISTONE H4; LYSINE; MESSENGER RNA; AZACITIDINE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; HISTONE DEACETYLASES; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 84921496342     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2014.12.004     Document Type: Article
Times cited : (60)

References (46)
  • 3
    • 84890060947 scopus 로고    scopus 로고
    • Sun exposure, sunbeds and sunscreens and melanoma. What are the controversies?
    • Bataille V. Sun exposure, sunbeds and sunscreens and melanoma. What are the controversies?. Curr. Oncol. Rep. 2013, 15:526-532.
    • (2013) Curr. Oncol. Rep. , vol.15 , pp. 526-532
    • Bataille, V.1
  • 5
    • 84874496172 scopus 로고    scopus 로고
    • Contact lens wearing and chronic cigarette smoking positively correlate with TGF-β1 and VEGF tear levels and impaired corneal wound healing after photorefractive keratectomy
    • Roszkowska A.M., De Grazia L., Visalli M., Mondello M., Teti D., Venza M., Venza I. Contact lens wearing and chronic cigarette smoking positively correlate with TGF-β1 and VEGF tear levels and impaired corneal wound healing after photorefractive keratectomy. Curr. Eye Res. 2013, 38:335-341.
    • (2013) Curr. Eye Res. , vol.38 , pp. 335-341
    • Roszkowska, A.M.1    De Grazia, L.2    Visalli, M.3    Mondello, M.4    Teti, D.5    Venza, M.6    Venza, I.7
  • 11
    • 0037189033 scopus 로고    scopus 로고
    • A melanoma-predisposing germline CDKN2A mutation with functional significance for both p16 and p14ARF
    • Hashemi J., Lindström M.S., Asker C., Platz A., Hansson J., Wiman K.G. A melanoma-predisposing germline CDKN2A mutation with functional significance for both p16 and p14ARF. Cancer Lett. 2002, 180:211-221.
    • (2002) Cancer Lett. , vol.180 , pp. 211-221
    • Hashemi, J.1    Lindström, M.S.2    Asker, C.3    Platz, A.4    Hansson, J.5    Wiman, K.G.6
  • 14
    • 0033560166 scopus 로고    scopus 로고
    • INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma
    • INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma. Oncogene 1999, 18:2527-2532.
    • (1999) Oncogene , vol.18 , pp. 2527-2532
    • Fujimoto, A.1    Morita, R.2    Hatta, N.3    Takehara, K.4    Takata, M.5
  • 16
    • 78149464297 scopus 로고    scopus 로고
    • High frequency of p16(INK4A) promoter methylation in NRAS-mutated cutaneous melanoma
    • Jonsson A., Tuominen R., Grafström E., Hansson J., Egyhazi S. High frequency of p16(INK4A) promoter methylation in NRAS-mutated cutaneous melanoma. J. Investig. Dermatol. 2010, 130:2809-2817.
    • (2010) J. Investig. Dermatol. , vol.130 , pp. 2809-2817
    • Jonsson, A.1    Tuominen, R.2    Grafström, E.3    Hansson, J.4    Egyhazi, S.5
  • 18
    • 0036727852 scopus 로고    scopus 로고
    • Mutational analysis of selected genes in the TGFbeta, Wnt, pRb, and p53 pathways in primary uveal melanoma
    • Edmunds S.C., Kelsell D.P., Hungerford J.L., Cree I.A. Mutational analysis of selected genes in the TGFbeta, Wnt, pRb, and p53 pathways in primary uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2002, 43:2845-2851.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 2845-2851
    • Edmunds, S.C.1    Kelsell, D.P.2    Hungerford, J.L.3    Cree, I.A.4
  • 19
    • 0037712001 scopus 로고    scopus 로고
    • Methylation analysis of several tumour suppressor genes shows a low frequency of methylation of CDKN2A and RARB in uveal melanomas
    • Zeschnigk M., Tschentscher F., Lich C., Brandt B., Horsthemke B., Lohmann D.R. Methylation analysis of several tumour suppressor genes shows a low frequency of methylation of CDKN2A and RARB in uveal melanomas. Comp. Funct. Genom. 2003, 4:329-336.
    • (2003) Comp. Funct. Genom. , vol.4 , pp. 329-336
    • Zeschnigk, M.1    Tschentscher, F.2    Lich, C.3    Brandt, B.4    Horsthemke, B.5    Lohmann, D.R.6
  • 23
    • 84874349294 scopus 로고    scopus 로고
    • Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells
    • Venza I., Visalli M., Oteri R., Cucinotta M., Teti D., Venza M. Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells. Pigment Cell Melanoma Res. 2013, 26:193-204.
    • (2013) Pigment Cell Melanoma Res. , vol.26 , pp. 193-204
    • Venza, I.1    Visalli, M.2    Oteri, R.3    Cucinotta, M.4    Teti, D.5    Venza, M.6
  • 24
    • 34548427509 scopus 로고    scopus 로고
    • The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1
    • Ou Y.H., Chung P.H., Hsu F.F., Sun T.P., Chang W.Y., Shieh S.Y. The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1. EMBO J. 2007, 26:3968-3980.
    • (2007) EMBO J. , vol.26 , pp. 3968-3980
    • Ou, Y.H.1    Chung, P.H.2    Hsu, F.F.3    Sun, T.P.4    Chang, W.Y.5    Shieh, S.Y.6
  • 25
    • 0029670840 scopus 로고    scopus 로고
    • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
    • Hara E., Smith R., Parry D., Tahara H., Stone S., Peters G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 1996, 16:859-867.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 859-867
    • Hara, E.1    Smith, R.2    Parry, D.3    Tahara, H.4    Stone, S.5    Peters, G.6
  • 26
    • 80051789018 scopus 로고    scopus 로고
    • Interleukin-8 overexpression in astrocytomas is induced by prostaglandin E2 and is associated with the transcription factors CCAAT/enhancer-binding protein-β and CCAAT/enhancer-binding homologous protein
    • (discussion 721)
    • Venza M., Visalli M., Alafaci C., Caffo M., Caruso G., Salpietro F.M., Tomasello F., Teti D. Interleukin-8 overexpression in astrocytomas is induced by prostaglandin E2 and is associated with the transcription factors CCAAT/enhancer-binding protein-β and CCAAT/enhancer-binding homologous protein. Neurosurgery 2011, 69:713-721. (discussion 721).
    • (2011) Neurosurgery , vol.69 , pp. 713-721
    • Venza, M.1    Visalli, M.2    Alafaci, C.3    Caffo, M.4    Caruso, G.5    Salpietro, F.M.6    Tomasello, F.7    Teti, D.8
  • 30
    • 33845947971 scopus 로고    scopus 로고
    • Suppression of cancer cell migration and invasion by protein phosphatase 2A through dephosphorylation of mu- and m-calpains
    • Xu L., Deng X. Suppression of cancer cell migration and invasion by protein phosphatase 2A through dephosphorylation of mu- and m-calpains. J. Biol. Chem. 2006, 281:35567-35575.
    • (2006) J. Biol. Chem. , vol.281 , pp. 35567-35575
    • Xu, L.1    Deng, X.2
  • 34
    • 0032978249 scopus 로고    scopus 로고
    • Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma
    • Merbs S.L., Sidransky D. Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma. Invest. Ophthalmol. Vis. Sci. 1999, 40:779-783.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 779-783
    • Merbs, S.L.1    Sidransky, D.2
  • 37
    • 0038819652 scopus 로고    scopus 로고
    • The INK4a/ARF locus and melanoma
    • Sharpless N.E., Chin L. The INK4a/ARF locus and melanoma. Oncogene 2003, 22:3092-3098.
    • (2003) Oncogene , vol.22 , pp. 3092-3098
    • Sharpless, N.E.1    Chin, L.2
  • 41
    • 0036313607 scopus 로고    scopus 로고
    • Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase
    • Straume O., Smeds J., Kumar R., Hemminki K., Akslen L.A. Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase. Am. J. Pathol. 2002, 161:229-237.
    • (2002) Am. J. Pathol. , vol.161 , pp. 229-237
    • Straume, O.1    Smeds, J.2    Kumar, R.3    Hemminki, K.4    Akslen, L.A.5
  • 42
    • 84885845375 scopus 로고    scopus 로고
    • Long-term cadmium exposure leads to the enhancement of lymphocyte proliferation via down-regulating p16 by DNA hypermethylation
    • Yuan D., Ye S., Pan Y., Bao Y., Chen H., Shao C. Long-term cadmium exposure leads to the enhancement of lymphocyte proliferation via down-regulating p16 by DNA hypermethylation. Mutat. Res. 2013, 757:125-131.
    • (2013) Mutat. Res. , vol.757 , pp. 125-131
    • Yuan, D.1    Ye, S.2    Pan, Y.3    Bao, Y.4    Chen, H.5    Shao, C.6
  • 43
    • 0034103810 scopus 로고    scopus 로고
    • Loss of nuclear p16 protein expression correlates with increased tumor cell proliferation (Ki-67) and poor prognosis in patients with vertical growth phase melanoma
    • Straume O., Sviland L., Akslen L.A. Loss of nuclear p16 protein expression correlates with increased tumor cell proliferation (Ki-67) and poor prognosis in patients with vertical growth phase melanoma. Clin. Cancer Res. 2000, 6:1845-1853.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1845-1853
    • Straume, O.1    Sviland, L.2    Akslen, L.A.3
  • 45
    • 84875333898 scopus 로고    scopus 로고
    • Inhibition of breast tumor cell growth by ectopic expression of p16/INK4A via combined effects of cell cycle arrest, senescence and apoptotic induction, and angiogenesis inhibition
    • Lu Y., Zhang X., Zhang J. Inhibition of breast tumor cell growth by ectopic expression of p16/INK4A via combined effects of cell cycle arrest, senescence and apoptotic induction, and angiogenesis inhibition. J. Cancer 2012, 3:333-344.
    • (2012) J. Cancer , vol.3 , pp. 333-344
    • Lu, Y.1    Zhang, X.2    Zhang, J.3
  • 46
    • 84874394983 scopus 로고    scopus 로고
    • P16(INK) (4a) deficiency promotes DNA hyper-replication and genetic instability in melanocytes
    • Fung C., Pupo G.M., Scolyer R.A., Kefford R.F., Rizos H. p16(INK) (4a) deficiency promotes DNA hyper-replication and genetic instability in melanocytes. Pigment Cell Melanoma Res. 2013, 26:236-246.
    • (2013) Pigment Cell Melanoma Res. , vol.26 , pp. 236-246
    • Fung, C.1    Pupo, G.M.2    Scolyer, R.A.3    Kefford, R.F.4    Rizos, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.