Effects of HCM cTnI mutation R145G on troponin structure and modulation by PKA phosphorylation elucidated by molecular dynamics simulations

Biophysical Journal

Volumn 108, Issue 2, 2015, Pages 395-407

  Lindert, Steffen ^a,c   Cheng, Yuanhua ^d   Kekenes Huskey, Peter ^a,e   Regnier, Michael ^d   McCammon, J Andrew ^a,b,c  

^a San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NSF Center for Theoretical Biological Physics   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; TROPONIN I;

AMINO ACID SEQUENCE; CARDIOMEGALY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MISSENSE MUTATION; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; CARDIOMEGALY; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; TROPONIN I;

EID: 84921473973     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2014.11.3461     Document Type: Article

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