Study of viral pathogenesis in humanized mice

Current Opinion in Virology

Volumn 11, Issue , 2015, Pages 14-20

  Gaska, Jenna M ^a   Ploss, Alexander ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DENGUE VIRUS; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HERPESVIRIDAE; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; LIFE CYCLE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; TROPISM; VIRAL TROPISM; VIRUS INFECTION; VIRUS PATHOGENESIS; ANIMAL; DISEASE MODEL; HUMAN; IMMUNOLOGY; PATHOLOGY; SCID MOUSE; VIROLOGY; VIRUS DISEASES;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; MICE, SCID; VIRUS DISEASES;

EID: 84921456882     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2015.01.002     Document Type: Review

References (62)

1. T. Hatziioannou, Z. Ambrose, N.P.Y. Chung, M. Piatak, F. Yuan, C.M. Trubey, V. Coalter, R. Kiser, D. Schneider, and J. Smedley A macaque model of HIV-1 infection Proc Natl Acad Sci U S A 106 2009 4425 4429
2. J. Pietzsch, H. Gruell, S. Bournazos, B.M. Donovan, F. Klein, R. Diskin, M.S. Seaman, P.J. Bjorkman, J.V. Ravetch, and A. Ploss A mouse model for HIV-1 entry Proc Natl Acad Sci U S A 109 2012 15859 15864
3. R. Namikawa, H. Kaneshima, M. Lieberman, I.L. Weissman, and J.M. McCune Infection of the SCID-hu mouse by HIV-1 Science 242 1988 1684 1686
4. L.D. Shultz, M.A. Brehm, J.V. Garcia-Martinez, and D.L. Greiner Humanized mice for immune system investigation: progress, promise and challenges Nat Rev Immunol 12 2012 786 798
5. M.D. Marsden, and J.A. Zack HIV/AIDS eradication Bioorg Med Chem Lett 23 2013 4003 4010
6. S.K. Choudhary, N.M. Archin, M. Cheema, N.P. Dahl, J.V. Garcia, and D.M. Margolis Latent HIV-1 infection of resting CD4+ T cells in the humanized Rag2-/- c-/- mouse J Virol 86 2012 114 120
7. P.W. Denton, R. Olesen, S.K. Choudhary, N.M. Archin, A. Wahl, M.D. Swanson, M. Chateau, T. Nochi, J.F. Krisko, and R.A. Spagnuolo Generation of HIV latency in humanized BLT mice J Virol 86 2012 630 634
8. M.D. Marsden, M. Kovochich, N. Suree, S. Shimizu, R. Mehta, R. Cortado, G. Bristol, D.S. An, and J.A. Zack HIV latency in the humanized BLT mouse J Virol 86 2012 339 347
9. A. Halper-Stromberg, C.L. Lu, F. Klein, J.A. Horwitz, S. Bournazos, L. Nogueira, T.R. Eisenreich, C. Liu, A. Gazumyan, and U. Schaefer Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice Cell 2014 10.1016/j.cell.2014.07.043
10. A.B. Balazs, J. Chen, C.M. Hong, D.S. Rao, L. Yang, and D. Baltimore Antibody-based protection against HIV infection by vectored immunoprophylaxis Nature 481 2011 81 84
11. A. Balazs, Y. Ouyang, C. Hong, J. Chen, S. Nguyen, D. Rao, D. An, and D. Baltimore Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission Retrovirology 20 2014 296 300
12. T.E. Dudek, D.C. No, E. Seung, V.D. Vrbanac, L. Fadda, P. Bhoumik, C.L. Boutwell, K.A. Power, A.D. Gladden, and L. Battis Rapid evolution of HIV-1 to functional CD8+ T cell responses in humanized BLT mice Sci Transl Med 4 2012 143ra98
13. S. Bhatt, P.W. Gething, O.J. Brady, J.P. Messina, A.W. Farlow, C.L. Moyes, J.M. Drake, J.S. Brownstein, A.G. Hoen, and O. Sankoh The global distribution and burden of dengue Nature 496 2013 504 507
14. V.V. Costa, C.T. Fagundes, D.G. Souza, and M.M. Teixeira Inflammatory and innate immune responses in dengue infection: protection versus disease induction Am J Pathol 182 2013 1950 1961
15. R. Guabiraba, and B. Ryffel Dengue virus infection: current concepts in immune mechanisms and lessons from murine models Immunology 141 2014 143 156
16. S. Jaiswal, P. Pazoles, M. Woda, L.D. Shultz, D.L. Greiner, M.A. Brehm, and A. Mathew Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice Immunology 136 2012 334 343
17. N. Frias-Staheli, M. Dorner, S. Marukian, E. Billerbeck, R.N. Labitt, C.M. Rice, and A. Ploss Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing J Virol 88 2014 2205 2218
18. S. Blackley, Z. Kou, H. Chen, M. Quinn, R.C. Rose, J.J. Schlesinger, M. Coppage, and X. Jin Primary human splenic macrophages, but not T or B cells, are the principal target cells for dengue virus infection in vitro J Virol 81 2007 13325 13334
19. Z. Kou, M. Quinn, H. Chen, W.W.S.I. Rodrigo, R.C. Rose, J.J. Schlesinger, and X. Jin Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells J Med Virol 80 2008 134 146
20. J. Mota, and R. Rico-Hesse Humanized mice show clinical signs of dengue fever according to infecting virus genotype J Virol 83 2009 8638 8645
21. J. Cox, J. Mota, S. Sukupolvi-Petty, M.S. Diamond, and R. Rico-Hesse Mosquito bite delivery of dengue virus enhances immunogenicity and pathogenesis in humanized mice J Virol 86 2012 7637 7649
22. B.K. Berges, and A. Tanner Modelling of human herpesvirus infections in humanized mice J Gen Virol 95 2014 2106 2117
23. J.I. Cohen, A.S. Fauci, H. Varmus, and G.J. Nabel Epstein-Barr virus: an important vaccine target for cancer prevention Sci Transl Med 3 2011 107fs7
24. O. Chijioke, T. Azzi, D. Nadal, and C. Münz Innate immune responses against Epstein Barr virus infection J Leukoc Biol 94 2013 1185 1190
25. F. Heuts, M.E. Rottenberg, D. Salamon, E. Rasul, M. Adori, G. Klein, E. Klein, and N. Nagy T cells modulate Epstein-Barr virus latency phenotypes during infection of humanized mice J Virol 88 2014 3235 3245
26. R.E. White, P.C. Rämer, K.N. Naresh, S. Meixlsperger, L. Pinaud, C. Rooney, B. Savoldo, R. Coutinho, C. Bödör, and J. Gribben EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors J Clin Invest 122 2012 1487 1502
27. M.L. Harth-Hertle, B.A. Scholz, F. Erhard, L.V. Glaser, L. Dölken, R. Zimmer, and B. Kempkes Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9 PLoS Pathog 2013 9
28. K. Sato, N. Misawa, C. Nie, Y. Satou, D. Iwakiri, M. Matsuoka, R. Takahashi, K. Kuzushima, M. Ito, and K. Takada A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice Blood 117 2011 5663 5673
29. Y. Kuwana, M. Takei, M. Yajima, K.I. Imadome, H. Inomata, M. Shiozaki, N. Ikumi, T. Nozaki, H. Shiraiwa, and N. Kitamura Epstein-Barr virus induces erosive arthritis in humanized mice PLoS ONE 2011 6
30. B. Chatterjee, C.S. Leung, and C. Münz Animal models of Epstein Barr virus infection J Immunol Methods 2014 10.1016/j.jim.2014.04.009
31. C. Söderberg-Nauclér Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer? J Intern Med 259 2006 219 246
32. I. Slavuljica, D. Kveštak, P.C. Huszthy, K.K. Britt, and W.J.S. Jonjić Immunobiology of congenital cytomegalovirus infection of the central nervous system - the murine cytomegalovirus model Cell Mol Immunol 2014 10.1038/cmi.2014.51 Epub ahead of print
33. M.R. Schleiss Developing a vaccine against congenital cytomegalovirus (CMV) infection: what have we learned from animal models? Where Should We Go Next? Future Virol 8 2013 1161 1182
34. M.S. Smith, D.C. Goldman, A.S. Bailey, D.L. Pfaffle, C.N. Kreklywich, D.B. Spencer, F.A. Othieno, D.N. Streblow, J.V. Garcia, and W.H. Fleming Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model Cell Host Microbe 8 2010 284 291
35. T. Kawahara, L.F. Lisboa, S. Cader, D.N. Douglas, M. Nourbakhsh, C.H. Pu, J.T. Lewis, T.A. Churchill, A. Humar, and N.M. Kneteman Human cytomegalovirus infection in humanized liver chimeric mice Hepatol Res 43 2013 679 684
36. P. Banerjee, A. Tripp, M.D. Lairmore, L. Crawford, M. Sieburg, J.C. Ramos, W. Harrington, M.A. Beilke, and G. Feuer Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice Blood 115 2010 2640 2648
37. J. Villaudy, M. Wencker, N. Gadot, N.A. Gillet, J.Y. Scoazec, L. Gazzolo, M.G. Manz, C.R.M. Bangham, and M.D. Dodon Htlv-1 propels thymic human t cell development in 'human immune system' rag2-/- gamma c-/- mice PLoS Pathog 2011 7
38. K. Tezuka, R. Xun, M. Tei, T. Ueno, M. Tanaka, N. Takenouchi, and J.I. Fujisawa An animal model of adult T-cell leukemia: humanized mice with HTLV-1-specific immunity Blood 123 2014 346 355
39. K.E. Foreman, J. Friborg, B. Chandran, H. Katano, T. Sata, M. Mercader, G.J. Nabel, and B.J. Nickoloff Injection of human herpesvirus-8 in human skin engrafted on SCID mice induces Kaposi's sarcoma-like lesions J Dermatol Sci 26 2001 182 193
40. J.F. Moffat, L. Zerboni, P.R. Kinchington, C. Grose, H. Kaneshima, and A.M. Arvin Attenuation of the vaccine Oka strain of Varicella-zoster virus and role of glycoprotein C in alphaherpesvirus virulence demonstrated in the SCID-hu mouse J Virol 72 1998 965 974
41. M. Dandri, and M. Lütgehetmann Mouse models of hepatitis B and delta virus infection J Immunol Methods 2014 10.1016/j.jim.2014.03.002
42. E. Billerbeck, Y. De Jong, M. Dorner, C. De La Fuente, and A. Ploss Animal models for hepatitis C Curr Top Microbiol Immunol 369 2013 49 86
43. F.V. Chisari Hepatitis B virus transgenic mice: models of viral immunobiology and pathogenesis Curr Top Microbiol Immunol 206 1996 149 173
44. M. Dandri, M.R. Burda, E. Torok, J.M. Pollok, A. Iwanska, G. Sommer, X. Rogiers, C.E. Rogler, S. Gupta, and H. Will Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus Hepatology 33 2001 981 988
45. D.F. Mercer, D.E. Schiller, J.F. Elliott, D.N. Douglas, C. Hao, A. Rinfret, W.R. Addison, K.P. Fischer, T.A. Churchill, and J.R. Lakey Hepatitis C virus replication in mice with chimeric human livers Nat Med 7 2001 927 933
46. K.-D. Bissig, S.F. Wieland, P. Tran, M. Isogawa, T.T. Le, F.V. Chisari, and I.M. Verma Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment J Clin Invest 120 2010 924 930
47. A. Tesfaye, J. Stift, D. Maric, Q. Cui, H.P. Dienes, and S.M. Feinstone Chimeric mouse model for the infection of hepatitis B and C viruses PLOS ONE 2013 8
48. K. Kosaka, N. Hiraga, M. Imamura, S. Yoshimi, E. Murakami, T. Nakahara, Y. Honda, A. Ono, T. Kawaoka, and M. Tsuge A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections Biochem Biophys Res Commun 441 2013 230 235
49. T.L. Gutti, J.S. Knibbe, E. Makarov, J. Zhang, G.R. Yannam, S. Gorantla, Y. Sun, D.F. Mercer, H. Suemizu, and J.L. Wisecarver Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice Am J Pathol 184 2014 101 109
50. E. Wilson, J. Bial, G. Bial, B. Jensen, D. Greiner, M. Brehm, and M. Grompe Extensive double humanization of both liver and hematopoiesis in FRGN mice Stem Cell Res 13 2014 404 412
51. M.T. Bility, L. Cheng, Z. Zhang, Y. Luan, F. Li, L. Chi, L. Zhang, Z. Tu, Y. Gao, and Y. Fu Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages PLoS Pathog 2014 10
52. M.L. Washburn, M.T. Bility, L. Zhang, G.I. Kovalev, A. Buntzman, J.A. Frelinger, W. Barry, A. Ploss, C.M. Rice, and L. Su A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease Gastroenterology 140 2011 1334 1344
53. A. Ploss, M.J. Evans, V.A. Gaysinskaya, M. Panis, H. You, Y.P. de Jong, and C.M. Rice Human occludin is a hepatitis C virus entry factor required for infection of mouse cells Nature 457 2009 882 886
54. M. Dorner, J.A. Horwitz, J.B. Robbins, W.T. Barry, Q. Feng, K. Mu, C.T. Jones, J.W. Schoggins, M.T. Catanese, and D.R. Burton A genetically humanized mouse model for hepatitis C virus infection Nature 474 2011 208 211
55. M. Dorner, J.a Horwitz, B.M. Donovan, R.N. Labitt, W.C. Budell, T. Friling, A. Vogt, M.T. Catanese, T. Satoh, and T. Kawai Completion of the entire hepatitis C virus life cycle in genetically humanized mice Nature 501 2013 237 241
56. H. Yan, G. Zhong, G. Xu, W. He, Z. Jing, Z. Gao, Y. Huang, Y. Qi, B. Peng, and H. Wang Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus Elife 2012 2012
57. J. Zhao, K. Li, C. Wohlford-Lenane, S.S. Agnihothram, C. Fett, J. Zhao, M.J. Gale, R.S. Baric, L. Enjuanes, and T. Gallagher Rapid generation of a mouse model for Middle East respiratory syndrome Proc Natl Acad Sci U S A 111 2014 4970 4975
58. G. Valbuena, H. Halliday, V. Borisevich, Y. Goez, and B. Rockx A human lung xenograft mouse model of Nipah Virus infection PLoS Pathog 2014 10
59. H. Takeuchi, and T. Matano Host factors involved in resistance to retroviral infection Microbiol Immunol 52 2008 318 325
60. R.B. Ren, F. Costantini, E.J. Gorgacz, J.J. Lee, and V.R. Racaniello Transgenic mice expressing a human poliovirus receptor: a new model for poliomyelitis Cell 63 1990 353 362
61. M.B. Oldstone, H. Lewicki, D. Thomas, A. Tishon, S. Dales, J. Patterson, M. Manchester, D. Homann, D. Naniche, and A. Holz Measles virus infection in a transgenic model: virus-induced immunosuppression and central nervous system disease Cell 98 1999 629 640
62. J.E. Carette, M. Raaben, A.C. Wong, A.S. Herbert, G. Obernosterer, N. Mulherkar, A.I. Kuehne, P.J. Kranzusch, A.M. Griffin, and G. Ruthel Ebola virus entry requires the cholesterol transporter Niemann-Pick C1 Nature 477 2011 340 343