Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 1, 2015, Pages 239-248

  Arts, Florence A ^a   Velghe, Amélie I ^a   Stevens, Monique ^a,b   Renauld, Jean Christophe ^a,b   Essaghir, Ahmed ^a   Demoulin, Jean Baptiste ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

Author keywords

Brain calcification; Fahr disease; Imatinib; PDGFRB; Receptor degradation; STAT3

Indexed keywords

MUTANT PROTEIN; PHOSPHOLIPASE C GAMMA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; STAT3 PROTEIN;

AMINO ACID SUBSTITUTION; CALCINOSIS; DEGENERATIVE DISEASE; DRUG EFFECTS; EXTRAPYRAMIDAL SYNDROME; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MUTATION; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMINO ACID SUBSTITUTION; BASAL GANGLIA DISEASES; CALCINOSIS; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; MUTANT PROTEINS; MUTATION; NEURODEGENERATIVE DISEASES; PHOSPHOLIPASE C GAMMA; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-SIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84921450495     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12443     Document Type: Article

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