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Volumn 14, Issue 6, 2013, Pages 725-736

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

Author keywords

Dynamin inhibitors; Endocytosis; PDGF; Signaling; STAT3

Indexed keywords

DNA; DYNAMIN; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN INHIBITOR; STAT3 PROTEIN;

EID: 84878153692     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12061     Document Type: Article
Times cited : (33)

References (67)
  • 2
    • 67349103762 scopus 로고    scopus 로고
    • Signaling from endosomes: location makes a difference
    • Sadowski L, Pilecka I, Miaczynska M. Signaling from endosomes: location makes a difference. Exp Cell Res 2009;315:1601-1609.
    • (2009) Exp Cell Res , vol.315 , pp. 1601-1609
    • Sadowski, L.1    Pilecka, I.2    Miaczynska, M.3
  • 3
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: intertwining molecular networks
    • Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 2009;10:609-622.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    von Zastrow, M.2
  • 4
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL. Regulated portals of entry into the cell. Nature 2003;422:37-44.
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 5
    • 77955057786 scopus 로고    scopus 로고
    • Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis
    • Howes MT, Mayor S, Parton RG. Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol 2010;22:519-527.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 519-527
    • Howes, M.T.1    Mayor, S.2    Parton, R.G.3
  • 6
    • 79960720320 scopus 로고    scopus 로고
    • Molecular mechanism and physiological functions of clathrin-mediated endocytosis
    • McMahon HT, Boucrot E. Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol 2011;12:517-533.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 517-533
    • McMahon, H.T.1    Boucrot, E.2
  • 8
    • 0037598870 scopus 로고    scopus 로고
    • Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
    • Di Guglielmo GM, Le Roy C, Goodfellow AF, Wrana JL. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat Cell Biol 2003;5:410-421.
    • (2003) Nat Cell Biol , vol.5 , pp. 410-421
    • Di Guglielmo, G.M.1    Le Roy, C.2    Goodfellow, A.F.3    Wrana, J.L.4
  • 9
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, Di Fiore PP. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell 2008;15:209-219.
    • (2008) Dev Cell , vol.15 , pp. 209-219
    • Sigismund, S.1    Argenzio, E.2    Tosoni, D.3    Cavallaro, E.4    Polo, S.5    Di Fiore, P.P.6
  • 10
    • 46049089076 scopus 로고    scopus 로고
    • Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling
    • Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. Dev Cell 2008;15:37-48.
    • (2008) Dev Cell , vol.15 , pp. 37-48
    • Yamamoto, H.1    Sakane, H.2    Yamamoto, H.3    Michiue, T.4    Kikuchi, A.5
  • 12
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008;22:1276-1312.
    • (2008) Genes Dev , vol.22 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 13
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999;79:1283-1316.
    • (1999) Physiol Rev , vol.79 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 15
    • 0027235878 scopus 로고
    • Pool of ligand-bound platelet-derived growth factor beta-receptors remain activated and tyrosine phosphorylated after internalization
    • Sorkin A, Eriksson A, Heldin CH, Westermark B, Claesson-Welsh L. Pool of ligand-bound platelet-derived growth factor beta-receptors remain activated and tyrosine phosphorylated after internalization. J Cell Physiol 1993;156:373-382.
    • (1993) J Cell Physiol , vol.156 , pp. 373-382
    • Sorkin, A.1    Eriksson, A.2    Heldin, C.H.3    Westermark, B.4    Claesson-Welsh, L.5
  • 16
    • 1542289711 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-mediated signal transduction from endosomes
    • Wang Y, Pennock SD, Chen X, Kazlauskas A, Wang Z. Platelet-derived growth factor receptor-mediated signal transduction from endosomes. J Biol Chem 2004;279:8038-8046.
    • (2004) J Biol Chem , vol.279 , pp. 8038-8046
    • Wang, Y.1    Pennock, S.D.2    Chen, X.3    Kazlauskas, A.4    Wang, Z.5
  • 17
    • 0028120928 scopus 로고
    • Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain
    • Andersson M, Ostman A, Westermark B, Heldin CH. Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain. J Biol Chem 1994;269:926-930.
    • (1994) J Biol Chem , vol.269 , pp. 926-930
    • Andersson, M.1    Ostman, A.2    Westermark, B.3    Heldin, C.H.4
  • 20
    • 67449116833 scopus 로고    scopus 로고
    • Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling
    • Hellberg C, Schmees C, Karlsson S, Ahgren A, Heldin CH. Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling. Mol Biol Cell 2009;20:2856-2863.
    • (2009) Mol Biol Cell , vol.20 , pp. 2856-2863
    • Hellberg, C.1    Schmees, C.2    Karlsson, S.3    Ahgren, A.4    Heldin, C.H.5
  • 21
    • 33750509827 scopus 로고    scopus 로고
    • Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor
    • Karlsson S, Kowanetz K, Sandin A, Persson C, Ostman A, Heldin CH, Hellberg C. Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor. Mol Biol Cell 2006;17:4846-4855.
    • (2006) Mol Biol Cell , vol.17 , pp. 4846-4855
    • Karlsson, S.1    Kowanetz, K.2    Sandin, A.3    Persson, C.4    Ostman, A.5    Heldin, C.H.6    Hellberg, C.7
  • 24
    • 0029030937 scopus 로고
    • EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
    • Mu FT, Callaghan JM, Steele-Mortimer O, Stenmark H, Parton RG, Campbell PL, McCluskey J, Yeo JP, Tock EP, Toh BH. EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif. J Biol Chem 1995;270:13503-13511.
    • (1995) J Biol Chem , vol.270 , pp. 13503-13511
    • Mu, F.T.1    Callaghan, J.M.2    Steele-Mortimer, O.3    Stenmark, H.4    Parton, R.G.5    Campbell, P.L.6    McCluskey, J.7    Yeo, J.P.8    Tock, E.P.9    Toh, B.H.10
  • 25
    • 0020550999 scopus 로고
    • Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents
    • Ciechanover A, Schwartz AL, Dautry-Varsat A, Lodish HF. Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents. J Biol Chem 1983;258:9681-9689.
    • (1983) J Biol Chem , vol.258 , pp. 9681-9689
    • Ciechanover, A.1    Schwartz, A.L.2    Dautry-Varsat, A.3    Lodish, H.F.4
  • 26
    • 0025819331 scopus 로고
    • CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells
    • Metzelaar MJ, Wijngaard PL, Peters PJ, Sixma JJ, Nieuwenhuis HK, Clevers HC. CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. J Biol Chem 1991;266:3239-3245.
    • (1991) J Biol Chem , vol.266 , pp. 3239-3245
    • Metzelaar, M.J.1    Wijngaard, P.L.2    Peters, P.J.3    Sixma, J.J.4    Nieuwenhuis, H.K.5    Clevers, H.C.6
  • 27
    • 0041843750 scopus 로고    scopus 로고
    • An integrated model of epidermal growth factor receptor trafficking and signal transduction
    • Resat H, Ewald JA, Dixon DA, Wiley HS. An integrated model of epidermal growth factor receptor trafficking and signal transduction. Biophys J 2003;85:730-743.
    • (2003) Biophys J , vol.85 , pp. 730-743
    • Resat, H.1    Ewald, J.A.2    Dixon, D.A.3    Wiley, H.S.4
  • 28
    • 33947223260 scopus 로고    scopus 로고
    • Endosomal receptor kinetics determine the stability of intracellular growth factor signalling complexes
    • Tzafriri AR, Edelman ER. Endosomal receptor kinetics determine the stability of intracellular growth factor signalling complexes. Biochem J 2007;402:537-549.
    • (2007) Biochem J , vol.402 , pp. 537-549
    • Tzafriri, A.R.1    Edelman, E.R.2
  • 30
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • Rink J, Ghigo E, Kalaidzidis Y, Zerial M. Rab conversion as a mechanism of progression from early to late endosomes. Cell 2005;122:735-749.
    • (2005) Cell , vol.122 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 31
    • 0025971082 scopus 로고
    • Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor
    • Sorkin A, Westermark B, Heldin CH, Claesson-Welsh L. Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor. J Cell Biol 1991;112:469-478.
    • (1991) J Cell Biol , vol.112 , pp. 469-478
    • Sorkin, A.1    Westermark, B.2    Heldin, C.H.3    Claesson-Welsh, L.4
  • 38
    • 36348985073 scopus 로고    scopus 로고
    • Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II
    • Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol Pharmacol 2007;72:1425-1439.
    • (2007) Mol Pharmacol , vol.72 , pp. 1425-1439
    • Quan, A.1    McGeachie, A.B.2    Keating, D.J.3    van Dam, E.M.4    Rusak, J.5    Chau, N.6    Malladi, C.S.7    Chen, C.8    McCluskey, A.9    Cousin, M.A.10    Robinson, P.J.11
  • 39
    • 62549151303 scopus 로고    scopus 로고
    • A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes
    • Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P. A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell 2009;136:1110-1121.
    • (2009) Cell , vol.136 , pp. 1110-1121
    • Zoncu, R.1    Perera, R.M.2    Balkin, D.M.3    Pirruccello, M.4    Toomre, D.5    De Camilli, P.6
  • 40
    • 84858665104 scopus 로고    scopus 로고
    • Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane
    • Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J. Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A 2012;109:4419-4424.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 4419-4424
    • Sousa, L.P.1    Lax, I.2    Shen, H.3    Ferguson, S.M.4    De Camilli, P.5    Schlessinger, J.6
  • 42
    • 84934436076 scopus 로고    scopus 로고
    • Pharmacological inhibition of endocytic pathways: is it specific enough to be useful?
    • Ivanov AI. Pharmacological inhibition of endocytic pathways: is it specific enough to be useful? Methods Mol Biol 2008;440:15-33.
    • (2008) Methods Mol Biol , vol.440 , pp. 15-33
    • Ivanov, A.I.1
  • 43
    • 0028349735 scopus 로고
    • Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr, J.E.3
  • 44
    • 0028036513 scopus 로고
    • Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
    • Damke H, Baba T, Warnock DE, Schmid SL. Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol 1994;127:915-934.
    • (1994) J Cell Biol , vol.127 , pp. 915-934
    • Damke, H.1    Baba, T.2    Warnock, D.E.3    Schmid, S.L.4
  • 45
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE Jr. STATs and gene regulation. Science 1997;277:1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr, J.E.1
  • 47
    • 0035150990 scopus 로고    scopus 로고
    • Growth-factor-dependent mitogenesis requires two distinct phases of signalling
    • Jones SM, Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol 2001;3:165-172.
    • (2001) Nat Cell Biol , vol.3 , pp. 165-172
    • Jones, S.M.1    Kazlauskas, A.2
  • 50
    • 0034690026 scopus 로고    scopus 로고
    • Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity
    • Wang YZ, Wharton W, Garcia R, Kraker A, Jove R, Pledger WJ. Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity. Oncogene 2000;19:2075-2085.
    • (2000) Oncogene , vol.19 , pp. 2075-2085
    • Wang, Y.Z.1    Wharton, W.2    Garcia, R.3    Kraker, A.4    Jove, R.5    Pledger, W.J.6
  • 51
    • 0037135528 scopus 로고    scopus 로고
    • Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor
    • Ahn S, Kim J, Lucaveche CL, Reedy MC, Luttrell LM, Lefkowitz RJ, Daaka Y. Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor. J Biol Chem 2002;277:26642-26651.
    • (2002) J Biol Chem , vol.277 , pp. 26642-26651
    • Ahn, S.1    Kim, J.2    Lucaveche, C.L.3    Reedy, M.C.4    Luttrell, L.M.5    Lefkowitz, R.J.6    Daaka, Y.7
  • 52
    • 75149163629 scopus 로고    scopus 로고
    • SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin
    • Cao H, Chen J, Krueger EW, McNiven MA. SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin. Mol Cell Biol 2010;30:781-792.
    • (2010) Mol Cell Biol , vol.30 , pp. 781-792
    • Cao, H.1    Chen, J.2    Krueger, E.W.3    McNiven, M.A.4
  • 54
    • 79955520123 scopus 로고    scopus 로고
    • A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src
    • Wang Y, Cao H, Chen J, McNiven MA. A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src. Mol Biol Cell 2011;22:1529-1538.
    • (2011) Mol Biol Cell , vol.22 , pp. 1529-1538
    • Wang, Y.1    Cao, H.2    Chen, J.3    McNiven, M.A.4
  • 57
    • 77957284437 scopus 로고    scopus 로고
    • Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis
    • Conery AR, Sever S, Harlow E. Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis. Proc Natl Acad Sci U S A 2010;107:15461-15466.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15461-15466
    • Conery, A.R.1    Sever, S.2    Harlow, E.3
  • 58
    • 80052759856 scopus 로고    scopus 로고
    • Dynamin 2 associates with microtubules at mitosis and regulates cell cycle progression
    • Ishida N, Nakamura Y, Tanabe K, Li SA, Takei K. Dynamin 2 associates with microtubules at mitosis and regulates cell cycle progression. Cell Struct Funct 2011;36:145-154.
    • (2011) Cell Struct Funct , vol.36 , pp. 145-154
    • Ishida, N.1    Nakamura, Y.2    Tanabe, K.3    Li, S.A.4    Takei, K.5
  • 59
    • 79959585828 scopus 로고    scopus 로고
    • Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression
    • Joshi S, Braithwaite AW, Robinson PJ, Chircop M. Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression. Mol Cancer 2011;10:78.
    • (2011) Mol Cancer , vol.10 , pp. 78
    • Joshi, S.1    Braithwaite, A.W.2    Robinson, P.J.3    Chircop, M.4
  • 60
    • 59449088311 scopus 로고    scopus 로고
    • Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells
    • Liu YW, Surka MC, Schroeter T, Lukiyanchuk V, Schmid SL. Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells. Mol Biol Cell 2008;19:5347-5359.
    • (2008) Mol Biol Cell , vol.19 , pp. 5347-5359
    • Liu, Y.W.1    Surka, M.C.2    Schroeter, T.3    Lukiyanchuk, V.4    Schmid, S.L.5
  • 61
    • 51649130231 scopus 로고    scopus 로고
    • Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation
    • Kermorgant S, Parker PJ. Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J Cell Biol 2008;182:855-863.
    • (2008) J Cell Biol , vol.182 , pp. 855-863
    • Kermorgant, S.1    Parker, P.J.2
  • 62
    • 84866124328 scopus 로고    scopus 로고
    • Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation
    • Luwor RB, Chin X, McGeachie AB, Robinson PJ, Zhu HJ. Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation. Growth Factors 2012;30:220-229.
    • (2012) Growth Factors , vol.30 , pp. 220-229
    • Luwor, R.B.1    Chin, X.2    McGeachie, A.B.3    Robinson, P.J.4    Zhu, H.J.5
  • 63
    • 67650540827 scopus 로고    scopus 로고
    • Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription
    • Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M. Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription. J Biol Chem 2009;284:18115-18128.
    • (2009) J Biol Chem , vol.284 , pp. 18115-18128
    • Rashid, S.1    Pilecka, I.2    Torun, A.3    Olchowik, M.4    Bielinska, B.5    Miaczynska, M.6
  • 64
    • 25144481466 scopus 로고    scopus 로고
    • Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis
    • Mace G, Miaczynska M, Zerial M, Nebreda AR. Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis. EMBO J 2005;24:3235-3246.
    • (2005) EMBO J , vol.24 , pp. 3235-3246
    • Mace, G.1    Miaczynska, M.2    Zerial, M.3    Nebreda, A.R.4
  • 66
    • 44649084521 scopus 로고    scopus 로고
    • Biotin labeling and quantitation of cell-surface proteins
    • Chapter 18:Unit 8 17.
    • Turvy DN, Blum JS. Biotin labeling and quantitation of cell-surface proteins. Curr Protoc Immunol 2001; Chapter 18:Unit 8 17.
    • (2001) Curr Protoc Immunol
    • Turvy, D.N.1    Blum, J.S.2
  • 67
    • 70350088552 scopus 로고    scopus 로고
    • Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex
    • Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M. Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex. Biochem J 2009;423:389-400.
    • (2009) Biochem J , vol.423 , pp. 389-400
    • Banach-Orlowska, M.1    Pilecka, I.2    Torun, A.3    Pyrzynska, B.4    Miaczynska, M.5


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