GSTpi protects against angiotensin II-induced proliferation and migration of vascular smooth muscle cells by preventing signal transducer and activator of transcription 3 activation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1843, Issue 2, 2014, Pages 454-463

  Chen, Dan ^a   Liu, Jinjiao ^a   Rui, Bing ^a   Gao, Min ^a   Zhao, Ningwei ^c   Sun, Shuai ^a   Bi, Aijing ^a   Yang, Tingting ^a   Guo, Yingtao ^b   Yin, Zhimin ^b   Luo, Lan ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING NORMAL UNIVERSITY   (China)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Angiotensin II; Glutathione S transferase pi; Signal transducer and activator of transcription 3; Vascular smooth muscle cells

Indexed keywords

ANGIOTENSIN II; CYCLIN D1; GLUTATHIONE TRANSFERASE P1; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR; STAT1 PROTEIN; STAT3 PROTEIN;

ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL MIGRATION; CELL PROLIFERATION; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; HYPERPLASIA; HYPERTROPHY; IMMUNOPRECIPITATION; NEOINTIMA; NITROSATIVE STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; VASCULAR SMOOTH MUSCLE;

3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYL-TETRAZOLIUM BROMIDE; ANG II; ANGIOTENSIN II; C-JUN NH2-TERMINAL KINASES; DIMETHYLSULFOXIDE; DMSO; G-GLUTAMYL-S-(BENZYL) CYSTEINYL-R-PHENYL GLYCINE DIETHYL ESTER; GLUTATHIONE; GLUTATHIONE S-TRANSFERASE PI; GSH; GSTPI; JAK2; JANUS-ACTIVATED KINASE 2; JNK; MTT; PBS; PHOSPHATE BUFFERED SOLUTION; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; STAT3; TLK199; TNF-Α; TRAF2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 2; VASCULAR SMOOTH MUSCLE CELLS; VSMCS;

ANGIOTENSIN II; ANIMALS; CELL MOVEMENT; CELL NUCLEUS; CELL PROLIFERATION; CYTOPROTECTION; GENE KNOCKDOWN TECHNIQUES; GLUTATHIONE S-TRANSFERASE PI; HYPERTROPHY; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR;

EID: 84890835939     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.11.024     Document Type: Article

References (34)

1. Rudijanto A. The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis. Acta Med. Indones. 2007, 39:86-93.
2. Schwartz S.M. Smooth muscle migration in atherosclerosis and restenosis. J. Clin. Invest. 1997, 100:S87-S89.
3. Haider U.G., Sorescu D., Griendling K.K., Vollmar A.M., Dirsch V.M. Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol. Pharmacol. 2002, 62:772-777.
4. Mehta P.K., Griendling K.K. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am. J. Physiol. Cell Physiol. 2007, 292:C82-C97.
5. Weiss D., Sorescu D., Taylor W.R. Angiotensin II and atherosclerosis. Am. J. Cardiol. 2001, 87:25C-32C.
6. Ram P.T., Iyengar R. G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation. Oncogene 2001, 20:1601-1606.
7. Potula H.S., Wang D., Quyen D.V., Singh N.K., Kundumani-Sridharan V., Karpurapu M., Park E.A., Glasgow W.C., Rao G.N. Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration. J. Biol. Chem. 2009, 284:31142-31155.
8. Touyz R.M., Schiffrin E.L. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol. Rev. 2000, 52:639-672.
9. Venema R.C., Venema V.J., Eaton D.C., Marrero M.B. Angiotensin II-induced tyrosine phosphorylation of signal transducers and activators of transcription 1 is regulated by Janus-activated kinase 2 and Fyn kinases and mitogen-activated protein kinase phosphatase 1. J. Biol. Chem. 1998, 273:30795-30800.
10. Ihle J.N. STATs: signal transducers and activators of transcription. Cell 1996, 84:331-334.
11. Marrero M.B., Schieffer B., Li B., Sun J., Harp J.B., Ling B.N. Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation. J. Biol. Chem. 1997, 272:24684-24690.
12. Schwaiberger A.V., Heiss E.H., Cabaravdic M., Oberan T., Zaujec J., Schachner D., Uhrin P., Atanasov A.G., Breuss J.M., Binder B.R., Dirsch V.M. Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo. Arterioscler. Thromb. Vasc. Biol. 2010, 30:2475-2481.
13. Wincewicz A., Sulkowska M., Rutkowski R., Sulkowski S., Musiatowicz B., Hirnle T., Famulski W., Koda M., Sokol G., Szarejko P. STAT1 and STAT3 as intracellular regulators of vascular remodeling. Eur. J. Intern. Med. 2007, 18:267-271.
14. Levy O., Granot Y. Arginine-vasopressin activates the JAK-STAT pathway in vascular smooth muscle cells. J. Biol. Chem. 2006, 281:15597-15604.
15. Tew K.D. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 1994, 54:4313-4320.
16. Tew K.D., Manevich Y., Grek C., Xiong Y., Uys J., Townsend D.M. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic. Biol. Med. 2011, 51:299-313.
17. Yin Z., Ivanov V.N., Habelhah H., Tew K., Ronai Z. Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. Cancer Res. 2000, 60:4053-4057.
18. Thevenin A.F., Zony C.L., Bahnson B.J., Colman R.F. GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Sci. 2011, 20:834-848.
19. Wu Y., Fan Y., Xue B., Luo L., Shen J., Zhang S., Jiang Y., Yin Z. Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals. Oncogene 2006, 25:5787-5800.
20. Gate L., Majumdar R.S., Lunk A., Tew K.D. Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. J. Biol. Chem. 2004, 279:8608-8616.
21. Ruscoe J.E., Rosario L.A., Wang T., Gate L., Arifoglu P., Wolf C.R., Henderson C.J., Ronai Z., Tew K.D. Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J. Pharmacol. Exp. Ther. 2001, 298:339-345.
22. Galili N., Tamayo P., Botvinnik O.B., Mesirov J.P., Brooks M.R., Brown G., Raza A. Prediction of response to therapy with ezatiostat in lower risk myelodysplastic syndrome. J. Hematol. Oncol. 2012, 5:20.
23. Ranganna K., Mathew O.P., Yatsu F.M., Yousefipour Z., Hayes B.E., Milton S.G. Involvement of glutathione/glutathione S-transferase antioxidant system in butyrate-inhibited vascular smooth muscle cell proliferation. FEBS J. 2007, 274:5962-5978.
24. Lang Y., Chen D., Li D., Zhu M., Xu T., Zhang T., Qian W., Luo Y. Luteolin inhibited hydrogen peroxide-induced vascular smooth muscle cells proliferation and migration by suppressing the Src and Akt signalling pathways. J. Pharm. Pharmacol. 2012, 64:597-603.
25. Tozer B.T., Cammack K.A., Smith H. Separation of antigens by immunological specificity. 2. Release of antigen and antibody from their complexes by aqueous carbon dioxide. Biochem. J. 1962, 84:80.
26. Liang H., Venema V.J., Wang X., Ju H., Venema R.C., Marrero M.B. Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells. J. Biol. Chem. 1999, 274:19846-19851.
27. Xiong Y., Uys J.D., Tew K.D., Townsend D.M. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid. Redox Signal. 2011, 15:233-270.
28. Townsend D.M., Manevich Y., He L., Hutchens S., Pazoles C.J., Tew K.D. Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J. Biol. Chem. 2009, 284:436-445.
29. Lacolley P., Regnault V., Nicoletti A., Li Z., Michel J.-B. The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles. Cardiovasc. Res. 2012, 95:194-204.
30. Xue B., Wu Y., Yin Z., Zhang H., Sun S., Yi T., Luo L. Regulation of lipopolysaccharide-induced inflammatory response by glutathione S-transferase P1 in RAW264.7 cells. FEBS Lett. 2005, 579:4081-4087.
31. Luo L., Wang Y., Feng Q., Zhang H., Xue B., Shen J., Ye Y., Han X., Ma H., Xu J., Chen D., Yin Z. Recombinant protein glutathione S-transferases P1 attenuates inflammation in mice. Mol. Immunol. 2009, 46:848-857.
32. Yang Y., Parsons K.K., Chi L., Malakauskas S.M., Le T.H. Glutathione S-transferase-micro1 regulates vascular smooth muscle cell proliferation, migration, and oxidative stress. Hypertension 2009, 54:1360-1368.
33. Cho S.G., Lee Y.H., Park H.S., Ryoo K., Kang K.W., Park J., Eom S.J., Kim M.J., Chang T.S., Choi S.Y., Shim J., Kim Y., Dong M.S., Lee M.J., Kim S.G., Ichijo H., Choi E.J. Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1. J. Biol. Chem. 2001, 276:12749-12755.
34. Lui V.W., Boehm A.L., Koppikar P., Leeman R.J., Johnson D., Ogagan M., Childs E., Freilino M., Grandis J.R. Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1. Mol. Pharmacol. 2007, 71:1435-1443.