Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels

Journal of Biological Chemistry

Volumn 290, Issue 4, 2015, Pages 2086-2098

  Poblete, Horacio ^a   Oyarzún, Ingrid ^b   Olivero, Pablo ^c   Comer, Jeffrey ^d   Zuñiga, Matías ^e   Sepulveda, Romina V ^e   Báez Nieto, David ^b   Leon, Carlos González ^b   González Nilo, Fernando ^b,e   Latorre, Ramón ^b  

^a UNIVERSIDAD DE TALCA   (Chile)

^b Centro Interdisciplinario de Neurociencias de Valparaíso   (Chile)

^c UNIVERSIDAD DE VALPARAÍSO   (Chile)

^d KANSAS STATE UNIVERSITY   (United States)

^e UNIVERSIDAD ANDRÉS BELLO   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; MOLECULAR DYNAMICS;

AMINO ACID RESIDUES; BINDING AFFINITIES; BINDING POCKETS; DELOCALIZATIONS; MOLECULAR DETERMINANTS; MOLECULAR DYNAMICS SIMULATIONS; PHOSPHATIDYLINOSITOL 4 ,5-BISPHOSPHATE; TRANSIENT RECEPTOR POTENTIALS;

SIGNAL TRANSDUCTION;

ARGININE; LYSINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; VANILLOID RECEPTOR 1; PROTEIN BINDING; TRPV1 PROTEIN, HUMAN; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHANNEL GATING; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; PROTEIN DOMAIN; ANIMAL; CHEMISTRY; COMPUTER SIMULATION; CRYOELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; HEK293 CELL LINE; HELA CELL LINE; MUTATION; PROTEIN TERTIARY STRUCTURE; RAT;

ANIMALS; ARGININE; BINDING SITES; COMPUTER SIMULATION; CRYOELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; HEK293 CELLS; HELA CELLS; HUMANS; LYSINE; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS; MUTATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; TRPV CATION CHANNELS;

EID: 84921440717     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.613620     Document Type: Article

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