Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability

Molecular Oncology

Volumn 9, Issue 2, 2015, Pages 437-449

  Greve, Katrine B V ^a   Lindgreen, Jonas N ^a   Terp, Mikkel G ^a   Pedersen, Christina B ^a   Schmidt, Steffen ^a   Mollenhauer, Jan ^a   Kristensen, Stine B ^a   Andersen, Rikke S ^a   Relster, Mette M ^a   Ditzel, Henrik J ^a,b   Gjerstorff, Morten F ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Cancer testis antigen; Genomic instability; Oncogene; Senescence; SSX2

Indexed keywords

BETA GALACTOSIDASE; CANCER TESTIS ANTIGEN; CYCLIN A; CYCLIN B; CYCLIN D; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 3; CYCLIN E; DOUBLE STRANDED DNA; PROTEIN P21; PROTEIN P53; SYNOVIAL SARCOMA X2 ANTIGEN; UNCLASSIFIED DRUG; REPRESSOR PROTEIN; SYNOVIAL SARCOMA X BREAKPOINT PROTEINS; TP53 PROTEIN, HUMAN; TUMOR PROTEIN;

A375 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CARCINOGENICITY; CELL AGING; CELL DIVISION; CELL GROWTH; CELL NUCLEUS; CELL SHAPE; CLONOGENESIS; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME ACTIVITY; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENE SILENCING; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MCF 7 CELL LINE; MITOSIS; MOUSE; NONHUMAN; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SENESCENCE; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; MELANOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

CELL AGING; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; MELANOMA; NEOPLASM PROTEINS; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921386240     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.09.001     Document Type: Article

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