Early developability screen of therapeutic antibody candidates using Taylor dispersion analysis and UV area imaging detection

mAbs

Volumn 7, Issue 1, 2015, Pages 77-83

  Lavoisier, Alexandra ^a   Schlaeppi, Jean Marc ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Developability assessment; Hydrodynamic radius; Monoclonal antibodies; Taylor dispersion; UV array imaging detection; Viscosity

Indexed keywords

MONOCLONAL ANTIBODY;

ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SCREENING; HUMAN; HYDRODYNAMICS; HYDROPHILICITY; MAJOR CLINICAL STUDY; NONHUMAN; NORMAL DISTRIBUTION; PREFORMULATION; QUALITY CONTROL; RISK ASSESSMENT; TAYLOR DISPERSION ANALYSIS; ULTRAVIOLET RADIATION; VISCOMETRY; CHEMISTRY; HEK293 CELL LINE;

ANTIBODIES, MONOCLONAL; HEK293 CELLS; HUMANS; HYDRODYNAMICS; ULTRAVIOLET RAYS;

EID: 84921367691     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/19420862.2014.985544     Document Type: Article

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