Nanomechanical property maps of breast cancer cells as determined by multiharmonic atomic force microscopy reveal SYK-dependent changes in microtubule stability mediated by map1b

Biochemistry

Volumn 54, Issue 1, 2015, Pages 60-68

  Krisenko, Mariya O ^a,c   Cartagena, Alexander ^a,d   Raman, Arvind ^b,d   Geahlen, Robert L ^a,c  

^a Department of Medicinal Chemistry and Molecular Pharmacology ^*  (United States)

^b School of Mechanical Engineering   (United States)

^c Purdue University   (United States)

^d Purdue University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ATOMIC FORCE MICROSCOPY; CELL SIGNALING; CYTOLOGY; DISEASES; MACHINERY; SIGNAL TRANSDUCTION; VISCOSITY;

BREAST CANCER CELLS; IMMUNE RECOGNITION; MICROTUBULE NETWORKS; MICROTUBULE STABILITY; NANOMECHANICAL PROPERTY; PROTEIN TYROSINE KINASE; RECEPTOR SIGNALING; TUMOR PROGRESSIONS;

CELLS;

MAP1B PROTEIN; MEMBRANE PROTEIN; NOCODAZOLE; PROTEIN KINASE SYK; UNCLASSIFIED DRUG; MAP1B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ACETYLATION; ARTICLE; ATOMIC FORCE MICROSCOPY; BREAST CANCER; BREAST CANCER CELL LINE; CELLULAR DISTRIBUTION; CHEMICAL PARAMETERS; CONTROLLED STUDY; DEPOLYMERIZATION; ELASTICITY; MICROTUBULE; MOLECULAR STABILITY; NANOMECHANICAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VISCOSITY; BREAST TUMOR; FEMALE; HUMAN; METABOLISM; NANOTECHNOLOGY; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, ATOMIC FORCE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NANOTECHNOLOGY; PROTEIN-TYROSINE KINASES;

EID: 84921342234     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500325n     Document Type: Article

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