-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
0034113808
-
Primary prevention of hepatocellular carcinoma in developing countries
-
Wild CP, Hall AJ. Primary prevention of hepatocellular carcinoma in developing countries. Mutat Res 2000;462:381-93.
-
(2000)
Mutat Res
, vol.462
, pp. 381-393
-
-
Wild, C.P.1
Hall, A.J.2
-
3
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999;340:745-50.
-
(1999)
N Engl J Med
, vol.340
, pp. 745-750
-
-
El-Serag, H.B.1
Mason, A.C.2
-
4
-
-
0028965102
-
Hepatic resection for hepatocellular carcinoma. An audit of 343 patients
-
Lai EC, Fan ST, Lo CM, et al. Hepatic resection for hepatocellular carcinoma. An audit of 343 patients. Ann Surg 1995;221:291-8.
-
(1995)
Ann Surg
, vol.221
, pp. 291-298
-
-
Lai, E.C.1
Fan, S.T.2
Lo, C.M.3
-
5
-
-
0028851163
-
Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma
-
Vauthey JN, Klimstra D, Franceschi D, et al. Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma. Am J Surg 1995;169:28-34.
-
(1995)
Am J Surg
, vol.169
, pp. 28-34
-
-
Vauthey, J.N.1
Klimstra, D.2
Franceschi, D.3
-
6
-
-
0642307263
-
The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-Year survival has improved significantly with time
-
Yoo HY, Patt CH, Geschwind JF, Thuluvath PJ. The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-year survival has improved significantly with time. J Clin Oncol 2003;21:4329-35.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4329-4335
-
-
Yoo, H.Y.1
Patt, C.H.2
Geschwind, J.F.3
Thuluvath, P.J.4
-
7
-
-
27144557565
-
A randomized phase III study of doxorubicin versus cisplatin/interferon α-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
-
Yeo W, Mok TS, Zee B, et al. A randomized phase III study of doxorubicin versus cisplatin/interferon α-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 2005;97:1532-8.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1532-1538
-
-
Yeo, W.1
Mok, T.S.2
Zee, B.3
-
8
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002;31:339-46.
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
9
-
-
0037061766
-
Genetic mechanisms of hepatocarcinogenesis
-
Feitelson MA, Sun B, Satiroglu Tufan NL, Liu J, Pan J, Lian Z. Genetic mechanisms of hepatocarcinogenesis. Oncogene 2002;21:2593-604.
-
(2002)
Oncogene
, vol.21
, pp. 2593-2604
-
-
Feitelson, M.A.1
Sun, B.2
Satiroglu Tufan, N.L.3
Liu, J.4
Pan, J.5
Lian, Z.6
-
10
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-28.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
11
-
-
0141648473
-
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
-
Lee S, Lee HJ, Kim JH, Lee HS, Jang JJ, Kang GH. Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am J Pathol 2003;163:1371-8.
-
(2003)
Am J Pathol
, vol.163
, pp. 1371-1378
-
-
Lee, S.1
Lee, H.J.2
Kim, J.H.3
Lee, H.S.4
Jang, J.J.5
Kang, G.H.6
-
12
-
-
0041924707
-
Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma
-
Yang B, Guo M, Herman JG, Clark DP. Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. Am J Pathol 2003;163:1101-7.
-
(2003)
Am J Pathol
, vol.163
, pp. 1101-1107
-
-
Yang, B.1
Guo, M.2
Herman, J.G.3
Clark, D.P.4
-
13
-
-
0037468934
-
Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma
-
Schagdarsurengin U, Wilkens L, Steinemann D, et al. Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene 2003;22:1866-71.
-
(2003)
Oncogene
, vol.22
, pp. 1866-1871
-
-
Schagdarsurengin, U.1
Wilkens, L.2
Steinemann, D.3
-
14
-
-
0034597517
-
Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3σ gene in human hepatocellular carcinoma
-
Iwata N, Yamamoto H, Sasaki S, et al. Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3σ gene in human hepatocellular carcinoma. Oncogene 2000;19:5298-302.
-
(2000)
Oncogene
, vol.19
, pp. 5298-5302
-
-
Iwata, N.1
Yamamoto, H.2
Sasaki, S.3
-
15
-
-
0035879017
-
Hypermethylation leads to silencing of the SYK gene in human breast cancer
-
Yuan Y, Mendez R, Sahin A, Dai JL. Hypermethylation leads to silencing of the SYK gene in human breast cancer. Cancer Res 2001;61:5558-61.
-
(2001)
Cancer Res
, vol.61
, pp. 5558-5561
-
-
Yuan, Y.1
Mendez, R.2
Sahin, A.3
Dai, J.L.4
-
16
-
-
0038707589
-
Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia
-
Goodman PA, Burkhardt N, Juran B, Tibbles HE, Uckun FM. Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia. Oncogene 2003;22:2504-14.
-
(2003)
Oncogene
, vol.22
, pp. 2504-2514
-
-
Goodman, P.A.1
Burkhardt, N.2
Juran, B.3
Tibbles, H.E.4
Uckun, F.M.5
-
17
-
-
0034680108
-
The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells
-
Coopman PJ, Do MT, Barth M, et al. The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells. Nature 2000;406:742-7.
-
(2000)
Nature
, vol.406
, pp. 742-747
-
-
Coopman, P.J.1
Do, M.T.2
Barth, M.3
-
18
-
-
0043136678
-
Alternative splicing disrupts a nuclear localization signal in spleen tyrosine kinase that is required for invasion suppression in breast cancer
-
Wang L, Duke L, Zhang PS, et al. Alternative splicing disrupts a nuclear localization signal in spleen tyrosine kinase that is required for invasion suppression in breast cancer. Cancer Res 2003;63:4724-30.
-
(2003)
Cancer Res
, vol.63
, pp. 4724-4730
-
-
Wang, L.1
Duke, L.2
Zhang, P.S.3
-
19
-
-
0037458567
-
Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor κB-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3′-kinase activity in breast cancer cells
-
Mahabeleshwar GH, Kundu GC. Syk, a protein-tyrosine kinase, suppresses the cell motility and nuclear factor κB-mediated secretion of urokinase type plasminogen activator by inhibiting the phosphatidylinositol 3′-kinase activity in breast cancer cells. J Biol Chem 2003;278:6209-21.
-
(2003)
J Biol Chem
, vol.278
, pp. 6209-6221
-
-
Mahabeleshwar, G.H.1
Kundu, G.C.2
-
20
-
-
5644271510
-
Progressive loss of Syk and abnormal proliferation in breast cancer cells
-
Moroni M, Soldatenkov V, Zhang L, et al. Progressive loss of Syk and abnormal proliferation in breast cancer cells. Cancer Res 2004;64:7346-54.
-
(2004)
Cancer Res
, vol.64
, pp. 7346-7354
-
-
Moroni, M.1
Soldatenkov, V.2
Zhang, L.3
-
21
-
-
20544451947
-
The non-receptor-associated tyrosine kinase Syk is a regulator of metastatic behavior in human melanoma cells
-
Hoeller C, Thallinger C, Pratscher B, et al. The non-receptor-associated tyrosine kinase Syk is a regulator of metastatic behavior in human melanoma cells. J Invest Dermatol 2005;124:1293-9.
-
(2005)
J Invest Dermatol
, vol.124
, pp. 1293-1299
-
-
Hoeller, C.1
Thallinger, C.2
Pratscher, B.3
-
22
-
-
0037427571
-
Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer
-
Toyama T, Iwase H, Yamashita H, et al. Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer. Cancer Lett 2003;189:97-102.
-
(2003)
Cancer Lett
, vol.189
, pp. 97-102
-
-
Toyama, T.1
Iwase, H.2
Yamashita, H.3
-
23
-
-
11144357007
-
Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer
-
Graziano F, Arduini F, Ruzzo A, et al. Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer. Clin Cancer Res 2004;10:2784-9.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2784-2789
-
-
Graziano, F.1
Arduini, F.2
Ruzzo, A.3
-
24
-
-
18644384743
-
Tissue inhibitor of metalloproteinase-3 (TIMP3) gene is methylated in the development of esophageal adenocarcinoma: Loss of expression correlates with poor prognosis
-
Darnton SJ, Hardie LJ, Muc RS, Wild CP, Casson AG. Tissue inhibitor of metalloproteinase-3 (TIMP3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis. Int J Cancer 2005;115:351-8.
-
(2005)
Int J Cancer
, vol.115
, pp. 351-358
-
-
Darnton, S.J.1
Hardie, L.J.2
Muc, R.S.3
Wild, C.P.4
Casson, A.G.5
-
25
-
-
33744726186
-
-
Sobin LH, Wittekind C, editors. New York: John Wiley & Sons
-
Sobin LH, Wittekind C, editors. UICC TNM classification of malignant tumors. 6th ed. New York: John Wiley & Sons; 2002. p. 81-6.
-
(2002)
UICC TNM Classification of Malignant Tumors. 6th Ed.
, pp. 81-86
-
-
-
26
-
-
0037328351
-
Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
-
House MG, Guo M, Iacobuzio-Donahue C, Herman JG. Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Carcinogenesis 2003;24:193-8.
-
(2003)
Carcinogenesis
, vol.24
, pp. 193-198
-
-
House, M.G.1
Guo, M.2
Iacobuzio-Donahue, C.3
Herman, J.G.4
-
27
-
-
0033740401
-
E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia
-
Corn PG, Smith BD, Ruckdeschel ES, Douglas D, Baylin SB, Herman JG. E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia. Clin Cancer Res 2000;6:4243-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4243-4248
-
-
Corn, P.G.1
Smith, B.D.2
Ruckdeschel, E.S.3
Douglas, D.4
Baylin, S.B.5
Herman, J.G.6
-
28
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graft JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996;93:9821-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graft, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
29
-
-
11144291007
-
Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness
-
Yuan Y, Liu H, Sahin A, Dai JL. Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness. Int J Cancer 2005;113:654-9.
-
(2005)
Int J Cancer
, vol.113
, pp. 654-659
-
-
Yuan, Y.1
Liu, H.2
Sahin, A.3
Dai, J.L.4
-
30
-
-
0035132145
-
Aberrant promoter methylation of multiple genes in non-small cell lung cancers
-
Zochbauer-Muller S, Fong KM, Virmani AK, Geradts J, Gazdar AF, Minna JD. Aberrant promoter methylation of multiple genes in non-small cell lung cancers. Cancer Res 2001;61:249-55.
-
(2001)
Cancer Res
, vol.61
, pp. 249-255
-
-
Zochbauer-Muller, S.1
Fong, K.M.2
Virmani, A.K.3
Geradts, J.4
Gazdar, A.F.5
Minna, J.D.6
-
31
-
-
0032401808
-
Aging and DNA methylation in colorectal mucosa and cancer
-
Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JP. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 1998;58:5489-94.
-
(1998)
Cancer Res
, vol.58
, pp. 5489-5494
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.5
-
32
-
-
0028849277
-
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas
-
Graff JR, Herman JG, Lapidus RG, et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res 1995;55:5195-9.
-
(1995)
Cancer Res
, vol.55
, pp. 5195-5199
-
-
Graff, J.R.1
Herman, J.G.2
Lapidus, R.G.3
-
33
-
-
0033558192
-
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
-
Bachman KE, Herman JG, Corn PG, et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res 1999;59:798-802.
-
(1999)
Cancer Res
, vol.59
, pp. 798-802
-
-
Bachman, K.E.1
Herman, J.G.2
Corn, P.G.3
-
34
-
-
0036725378
-
Altered expression of E-cadherin in hepatocellular carcinoma: Correlations with genetic alterations, β-catenin expression, and clinical features
-
Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA. Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, β-catenin expression, and clinical features. Hepatology 2002;36:692-701.
-
(2002)
Hepatology
, vol.36
, pp. 692-701
-
-
Wei, Y.1
Van Nhieu, J.T.2
Prigent, S.3
Srivatanakul, P.4
Tiollais, P.5
Buendia, M.A.6
-
36
-
-
1242296351
-
Favorable surgical outcomes in patients with early hepatocellular carcinoma
-
Yamamoto M, Takasaki K, Otsubo T, et al. Favorable surgical outcomes in patients with early hepatocellular carcinoma. Ann Surg 2004;239:395-9.
-
(2004)
Ann Surg
, vol.239
, pp. 395-399
-
-
Yamamoto, M.1
Takasaki, K.2
Otsubo, T.3
-
37
-
-
0035014082
-
Underlying liver disease, not tumor factors, predicts long-term survival after resection of hepatocellular carcinoma
-
Bilimoria MM, Lauwers GY Doherty DA, et al. Underlying liver disease, not tumor factors, predicts long-term survival after resection of hepatocellular carcinoma. Arch Surg 2001;136:528-35.
-
(2001)
Arch Surg
, vol.136
, pp. 528-535
-
-
Bilimoria, M.M.1
Lauwers, G.Y.2
Doherty, D.A.3
-
38
-
-
0037087696
-
Simplified staging for hepatocellular carcinoma
-
Vauthey JN, Lauwers GY, Esnaola NF, et al. Simplified staging for hepatocellular carcinoma. J Clin Oncol 2002;20:1527-36.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1527-1536
-
-
Vauthey, J.N.1
Lauwers, G.Y.2
Esnaola, N.F.3
-
39
-
-
0036534375
-
Tumor microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: A prospective study
-
Poon RT, Ng IO, Lau C, et al. Tumor microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: a prospective study. J Clin Oncol 2002;20:1775-85.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1775-1785
-
-
Poon, R.T.1
Ng, I.O.2
Lau, C.3
-
40
-
-
0033766176
-
Acquired expression of p27 is a favorable prognostic indicator in patients with hepatocellular carcinoma
-
Fiorentino M, Altimari A, D'Errico A, et al. Acquired expression of p27 is a favorable prognostic indicator in patients with hepatocellular carcinoma. Clin Cancer Res 2000;6:3966-72.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3966-3972
-
-
Fiorentino, M.1
Altimari, A.2
D'Errico, A.3
-
41
-
-
15144343103
-
p53 mutation is a poor prognostic indicator for survival in patients with hepatocellular carcinoma undergoing surgical tumour ablation
-
Honda K, Sbisa E, Tullo A, et al. p53 mutation is a poor prognostic indicator for survival in patients with hepatocellular carcinoma undergoing surgical tumour ablation. Br J Cancer 1998;77:776-82.
-
(1998)
Br J Cancer
, vol.77
, pp. 776-782
-
-
Honda, K.1
Sbisa, E.2
Tullo, A.3
-
42
-
-
0037094189
-
DNA methylation and environmental exposures in human hepatocellular carcinoma
-
Shen L, Ahuja N, Shen Y, et al. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst 2002;94:755-61.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 755-761
-
-
Shen, L.1
Ahuja, N.2
Shen, Y.3
-
43
-
-
0037068358
-
Reactivating the expression of methylation silenced genes in human cancer
-
Karpf AR, Jones DA. Reactivating the expression of methylation silenced genes in human cancer. Oncogene 2002;21:5496-503.
-
(2002)
Oncogene
, vol.21
, pp. 5496-5503
-
-
Karpf, A.R.1
Jones, D.A.2
-
44
-
-
0035799382
-
Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
-
Santini V, Kantarjian HM, Issa JP. Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann Intern Med 2001;134:573-86.
-
(2001)
Ann Intern Med
, vol.134
, pp. 573-586
-
-
Santini, V.1
Kantarjian, H.M.2
Issa, J.P.3
-
45
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa JP, Garcia-Manero G, Giles FJ, et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004;103:1635-40.
-
(2004)
Blood
, vol.103
, pp. 1635-1640
-
-
Issa, J.P.1
Garcia-Manero, G.2
Giles, F.J.3
-
46
-
-
1642499364
-
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells
-
Cheng JC, Weisenberger DJ, Gonzales FA, et al. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol 2004;24:1270-8.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1270-1278
-
-
Cheng, J.C.1
Weisenberger, D.J.2
Gonzales, F.A.3
|