Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2

Journal of Applied Physiology

Volumn 118, Issue 2, 2015, Pages 224-237

  Sun, Chengcao ^a   Yang, Cuili ^a   Xue, Ruilin ^a   Li, Shujun ^a   Zhang, Ting ^a   Pan, Lei ^a   Ma, Xuejiao ^a   Wang, Liang ^a   Li, Dejia ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Duchenne muscular dystrophy; Nrf2; Oxidative stress; Sulforaphane

Indexed keywords

ANTINEOPLASTIC AGENT; HEME OXYGENASE 1; HMOX1 PROTEIN, MOUSE; ISOTHIOCYANIC ACID DERIVATIVE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; NQO1 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFORAFAN; TRANSCRIPTION FACTOR NRF2;

ANIMAL; ANTIOXIDANT RESPONSIVE ELEMENT; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; HEART; INFLAMMATION; MALE; METABOLISM; MUSCULAR DYSTROPHY, ANIMAL; OXIDATIVE STRESS; PRECLINICAL STUDY; RANDOMIZATION; SARCOLEMMA; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANT RESPONSE ELEMENTS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION; HEART; HEME OXYGENASE-1; INFLAMMATION; ISOTHIOCYANATES; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RANDOM ALLOCATION; SARCOLEMMA; SIGNAL TRANSDUCTION;

EID: 84921325237     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00744.2014     Document Type: Article

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