A mutation in the intracellular loop III/IV of mosquito sodium channel synergizes the effect of mutations in helix IIS6 on pyrethroid resistance

Molecular Pharmacology

Volumn 87, Issue 3, 2015, Pages 421-429

  Wang, Lingxin ^a   Nomura, Yoshiko ^a   Du, Yuzhe ^a   Liu, Nannan ^b   Zhorov, Boris S ^c,d   Dong, Ke ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

^c MCMASTER UNIVERSITY   (Canada)

^d SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE CARBAMOYLTRANSFERASE; PYRETHROID; SODIUM CHANNEL NAV1.1; INSECTICIDE; SODIUM CHANNEL;

AEDES AEGYPTI; ALLOSTERISM; ARTICLE; BINDING SITE; CHANNEL GATING; COMPUTER MODEL; CONTROLLED STUDY; HYDROPHILICITY; HYDROPHOBICITY; INSECTICIDE RESISTANCE; MUTANT; MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; XENOPUS; ANIMAL; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; GENETICS; MEMBRANE POTENTIAL; MOSQUITO; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; XENOPUS LAEVIS;

ANIMALS; CULICIDAE; DRUG RESISTANCE; FEMALE; INSECTICIDES; MEMBRANE POTENTIALS; MUTATION; PROTEIN STRUCTURE, SECONDARY; PYRETHRINS; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 84921305314     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.094730     Document Type: Article

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