Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 17, 2012, Pages 6614-6619

  Jones, Christopher M ^a   Liyanapathirana, Milindu ^a   Agossa, Fiacre R ^b   Weetman, David ^a   Ranson, Hilary ^a   Donnelly, Martin James ^a   Wilding, Craig S ^a  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b CENTRE DE RECHERCHE ENTOMOLOGIQUE DE COTONOU CREC   (Benin)

Author keywords

Inactivation particle; Kdr; Selective sweep

Indexed keywords

INSECTICIDE; VOLTAGE GATED SODIUM CHANNEL;

AFRICA; AMINO ACID SUBSTITUTION; ANOPHELES GAMBIAE; ARTICLE; CONTROLLED STUDY; EXON; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HAPLOTYPE; HETEROZYGOTE; HOMOZYGOTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL;

ANIMALS; ANOPHELES GAMBIAE; HAPLOTYPES; HOMOZYGOTE; INSECTICIDE RESISTANCE; ION CHANNEL GATING; MUTATION; SELECTION, GENETIC; SODIUM CHANNELS;

EID: 84860169353     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1201475109     Document Type: Article

References (43)

1. Hastings I (2011) How artemisinin-containing combination therapies slow the spread of antimalarial drug resistance. Trends Parasitol 27:67-72.
2. Lim SS, et al. (2011) Net benefits: A multicountry analysis of observational data examining associations between insecticide-treated mosquito nets and health outcomes. PLoS Med 8:e1001091.
3. Ranson H, et al. (2011) Pyrethroid resistance in African anopheline mosquitoes: What are the implications for malaria control? Trends Parasitol 27:91-98.
4. malERA Consultative Group on Vector Control (2011) A research agenda for malaria eradication: Vector control. PLoS Med 8:e1000401.
5. della Torre A, Tu Z, Petrarca V (2005) On the distribution and genetic differentiation of Anopheles gambiae s.s. molecular forms. Insect Biochem Mol Biol 35:755-769. (Pubitemid 40707638)
6. Weetman D, Wilding CS, Steen K, Pinto J, Donnelly MJ (2012) Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms. Mol Biol Evol 29: 279-291.
7. Lynd A, et al. (2010) Field, genetic, and modeling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s. Mol Biol Evol 27:1117-1125.
8. Donnelly MJ, et al. (2009) Does kdr genotype predict insecticide- resistance phenotype in mosquitoes? Trends Parasitol 25:213-219.
9. O'Reilly AO, et al. (2006) Modelling insecticide-binding sites in the voltage-gated sodium channel. Biochem J 396:255-263. (Pubitemid 43837241)
10. Davies TG, Field LM, Usherwood PN, Williamson MS (2007) DDT, pyrethrins, pyrethroids and insect sodium channels. IUBMB Life 59:151-162. (Pubitemid 46752476)
11. Martinez-Torres D, et al. (1998) Molecular characterization of pyrethroid knockdown resistance (kdr) in the majormalaria vectorAnopheles gambiae s.s. Insect Mol Biol 7:179-184. (Pubitemid 28107084)
12. Ranson H, et al. (2000) Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol 9:491-497.
13. ffrench-Constant RH, Daborn PJ, Le Goff G (2004) The genetics and genomics of insecticide resistance. Trends Genet 20:163-170.
14. Labbé P, et al. (2007) Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens. PLoS Genet 3:e205.
15. Karasov T, Messer PW, Petrov DA (2010) Evidence that adaptation in Drosophila is not limited by mutation at single sites. PLoS Genet 6:e1000924.
16. Pritchard JK, Pickrell JK, Coop G (2010) The genetics of human adaptation: Hard sweeps, soft sweeps, and polygenic adaptation. Curr Biol 20:R208-R215.
17. Neafsey DE, et al. (2010) SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes. Science 330:514-517.
18. Weetman D, et al. (2010) Association mapping of insecticide resistance in wild Anopheles gambiae populations: Major variants identified in a low-linkage disequilbrium genome. PLoS ONE 5:e13140.
19. Harris C, Rousset F, Morlais I, Fontenille D, Cohuet A (2010) Low linkage disequilibrium in wild Anopheles gambiae s.l. populations. BMC Genet 11:81.
20. Hamblin MT, Di Rienzo A (2000) Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus. Am J Hum Genet 66:1669-1679. (Pubitemid 30463085)
21. Tishkoff SA, et al. (2001) Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance. Science 293:455-462. (Pubitemid 32679066)
22. Harris AF, Rajatileka S, Ranson H (2010) Pyrethroid resistance in Aedes aegypti from Grand Cayman. Am J Trop Med Hyg 83:277-284.
23. Davies TGE, Williamson MS (2009) Interactions of pyrethroids with the voltage-gated sodium channel. Bayer Crop Science J 62:159-178.
24. Burton MJ, et al. (2011) Differential resistance of insect sodium channels with kdr mutations to deltamethrin, permethrin and DDT. Insect Biochem Mol Biol 41:723-732.
25. Head DJ, McCaffery AR, Callaghan A (1998) Novel mutations in the para-homologous sodium channel gene associated with phenotypic expression of nerve insensitivity resistance to pyrethroids in Heliothine lepidoptera. Insect Mol Biol 7:191-196. (Pubitemid 28107086)
26. Liu Z, Tan J, Huang ZY, Dong K (2006) Effect of a fluvalinate-resistance- associated sodium channel mutation from varroa mites on cockroach sodium channel sensitivity to fluvalinate, a pyrethroid insecticide. Insect Biochem Mol Biol 36:885-889. (Pubitemid 44548395)
27. Lindsay HA, et al. (2008) The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic. Genetics 180:873-884.
28. Vais H, Williamson MS, Devonshire AL, Usherwood PNR (2001) The molecular interactions of pyrethroid insecticides with insect and mammalian sodium channels. Pest Manag Sci 57:877-888. (Pubitemid 32979908)
29. Handel A, Regoes RR, Antia R (2006) The role of compensatory mutations in the emergence of drug resistance. PLOS Comput Biol 2:e137.
30. Smith MR, Goldin AL (1997) Interaction between the sodium channel inactivation linker and domain III S4-S5. Biophys J 73:1885-1895. (Pubitemid 27425719)
31. Barbosa S, Black WCIV, Hastings I (2011) Challenges in estimating insecticide selection pressures from mosquito field data. PLoS Negl Trop Dis 5:e1387.
32. Ranson H, et al. (2009) Insecticide resistance in Anopheles gambiae: Data from the first year of a multi-country study highlight the extent of the problem. Malar J 8:299.
33. World Health Organization (WHO). (1998) Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticide on treated surfaces (WHO, Geneva).
34. Santolamazza F, et al. (2008) Insertion polymorphisms of SINE200 retrotransposons within speciation islands of Anopheles gambiae molecular forms. Malar J 7:163.
35. Bass C, et al. (2010) The Vector Population Monitoring Tool (VPMT): High-throughput DNA-based diagnostics for the monitoring of mosquito vector populations. Malar Res Treat 2010:190434.
36. Bass C, et al. (2007) Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: A comparison of two new high-throughput assays with existing methods. Malar J 6:111.
37. Davies TGE, Field LM, Usherwood PNR, Williamson MS (2007) A comparative study of voltage-gated sodium channels in the Insecta: Implications for pyrethroid resistance in Anopheline and other Neopteran species. Insect Mol Biol 16:361-375. (Pubitemid 46733771)
38. Stephens M, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68:978-989. (Pubitemid 32289743)
39. Clement M, Posada D, Crandall KA (2000) TCS: A computer program to estimate gene genealogies. Mol Ecol 9:1657-1659.
40. Sabeti PC, et al. (2002) Detecting recent positive selection in the human genome from haplotype structure. Nature 419:832-837. (Pubitemid 35238568)
41. R Development Core Team (2011) R: A Language and Environment for Statistical Computing (R Foundation for Statistical Computing, Vienna, Austria).
42. Williamson MS, Martinez-Torres D, Hick CA, Devonshire AL (1996) Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides. Mol Gen Genet 252:51-60.
43. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265. (Pubitemid 40202029)