GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity

NeuroReport

Volumn 25, Issue 7, 2014, Pages 542-547

  Zhang, Yun ^a   Chen, Liyun ^a   Shen, Guangli ^a   Zhao, Qian ^a   Shangguan, Lijuan ^a   He, Maolin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

G protein coupled receptor kinase 5 dysfunction; Glycogen synthase kinase 3 ; Protein kinase C; Tau hyperphosphorylation

Indexed keywords

ACETYLCHOLINE; G PROTEIN COUPLED RECEPTOR KINASE 5; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; METHOCTRAMINE; MUSCARINIC M2 RECEPTOR; PROTEIN KINASE C; TAU PROTEIN; AMYLOID PRECURSOR PROTEIN; CHOLINERGIC RECEPTOR BLOCKING AGENT; DIAMINE; GPRK5 PROTEIN, RAT;

ACETYLCHOLINE RELEASE; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CHOLINERGIC ACTIVITY; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; CYTOSOLIC FRACTION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HIPPOCAMPUS; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPATIAL LEARNING; TISSUE LEVEL; WESTERN BLOTTING; AGING; ALZHEIMER DISEASE; ANIMAL; C57BL MOUSE; COMPLICATION; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; MAZE TEST; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; TRANSGENIC MOUSE;

ACETYLCHOLINE; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DIAMINES; DISEASE MODELS, ANIMAL; G-PROTEIN-COUPLED RECEPTOR KINASE 5; HIPPOCAMPUS; HUMANS; LITHIUM CHLORIDE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONS; PARASYMPATHOLYTICS; PHOSPHORYLATION; TAU PROTEINS;

EID: 84921273489     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000142     Document Type: Article

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