Phainanoids A-F, A new class of potent immunosuppressive triterpenoids with an unprecedented carbon skeleton from phyllanthus hainanensis

Journal of the American Chemical Society

Volumn 137, Issue 1, 2015, Pages 138-141

  Fan, Yao Yue ^a   Zhang, Hua ^a   Zhou, Yu ^a   Liu, Hong Bing ^a   Tang, Wei ^a   Zhou, Bin ^a   Zuo, Jian Ping ^a   Yue, Jian Min ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CRYSTALLOGRAPHY; MUSCULOSKELETAL SYSTEM;

ABSOLUTE CONFIGURATION; B LYMPHOCYTES; CARBON SKELETON; CHEMICAL METHOD; PHYLLANTHUS; SPECTROSCOPIC DATA; STRUCTURE ACTIVITY RELATIONSHIPS; TRITERPENOIDS;

X RAY CRYSTALLOGRAPHY;

IMMUNOSUPPRESSIVE AGENT; PHAINANOID A; PHAINANOID B; PHAINANOID C; PHAINANOID D; PHAINANOID DERIVATIVE; PHAINANOID E; PHAINANOID F; TRITERPENOID; UNCLASSIFIED DRUG; CARBON; CONCANAVALIN A; LIPOPOLYSACCHARIDE; TRITERPENE;

ARTICLE; B LYMPHOCYTE; DRUG POTENCY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; IC50; IN VITRO STUDY; NONHUMAN; PHYLLANTHUS; PHYLLANTHUS HAINANENSIS; PROTON NUCLEAR MAGNETIC RESONANCE; T LYMPHOCYTE; X RAY CRYSTALLOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; MOUSE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

ANIMALS; B-LYMPHOCYTES; CARBON; CELL PROLIFERATION; CELL SURVIVAL; CONCANAVALIN A; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOSUPPRESSIVE AGENTS; LIPOPOLYSACCHARIDES; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHYLLANTHUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; TRITERPENES;

EID: 84921062009     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja511813g     Document Type: Article

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