Ivorenolide a, an unprecedented immunosuppressive macrolide from khaya ivorensis: Structural elucidation and bioinspired total synthesis

Journal of the American Chemical Society

Volumn 134, Issue 51, 2012, Pages 20605-20608

  Zhang, Bo ^a   Wang, Yao ^b   Yang, Sheng Ping ^a   Zhou, Yu ^a   Wu, Wen Bin ^a   Tang, Wei ^a   Zuo, Jian Ping ^a   Li, Ying ^b   Yue, Jian Min ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIO-INSPIRED; CHIRAL CENTERS; KHAYA IVORENSIS; MACROLIDES; SINGLE CRYSTAL X-RAY DIFFRACTION; STRUCTURAL ELUCIDATION; TOTAL SYNTHESIS;

SPECTROSCOPIC ANALYSIS; X RAY DIFFRACTION;

METABOLITES;

CYCLOSPORIN A; GLYCOSIDE; IMMUNOSUPPRESSIVE AGENT; IVORENOLIDE A; MACROLIDE; PERIPLOCOSIDE A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; KHAYA IVORENSIS; MELIACEAE; MOUSE; NONHUMAN; STRUCTURE ANALYSIS;

ANIMALS; B-LYMPHOCYTES; CRYSTALLOGRAPHY, X-RAY; IMMUNOSUPPRESSIVE AGENTS; MACROLIDES; MELIACEAE; MICE; MODELS, MOLECULAR; STEREOISOMERISM; T-LYMPHOCYTES;

EID: 84871568616     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja310482z     Document Type: Article

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