Insights into caerulomycin A biosynthesis: A two-component monooxygenase CrmH-catalyzed oxime formation

Journal of the American Chemical Society

Volumn 135, Issue 50, 2013, Pages 18750-18753

  Zhu, Yiguang ^a   Zhang, Qingbo ^a,b   Li, Sumei ^a   Lin, Qinheng ^a,b   Fu, Peng ^c   Zhang, Guangtao ^a   Zhang, Haibo ^a   Shi, Rong ^d   Zhu, Weiming ^c   Zhang, Changsheng ^a  

^a SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

^d UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVIN REDUCTASE; FLAVIN-DEPENDENT; FOUR AMINO ACIDS; IMMUNOSUPPRESSIVE AGENT; MONOOXYGENASES; OXIME FORMATION; PRIMARY AMINES; SITE DIRECTED MUTAGENESIS;

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; ENZYME ACTIVITY;

CATALYSIS;

2,2' BIPYRIDINE DERIVATIVE; CERULOMYCIN; OXIME; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; ENZYME ANALYSIS; SITE DIRECTED MUTAGENESIS;

BIOCATALYSIS; CATALYTIC DOMAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OXIMES; PYRIDINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84890743826     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja410513g     Document Type: Article

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