Cavity as a source of conformational fluctuation and high-energy state: High-pressure NMR study of a cavity-enlarged mutant of T4lysozyme

Biophysical Journal

Volumn 108, Issue 1, 2015, Pages 133-145

  Maeno, Akihiro ^a,b   Sindhikara, Daniel ^c   Hirata, Fumio ^c   Otten, Renee ^d   Dahlquist, Frederick W ^e   Yokoyama, Shigeyuki ^f,g   Akasaka, Kazuyuki ^a,b   Mulder, Frans A A ^h   Kitahara, Ryo ^b,c  

^a KINKI UNIVERSITY   (Japan)

^b RIKEN SPring 8 Center   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

^d BRANDEIS UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f RIKEN   (Japan)

^g UNIVERSITY OF TOKYO   (Japan)

^h AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; LYSOZYME; RECOMBINANT PROTEIN; VIRAL PROTEIN; WATER;

CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER SIMULATION; ENTEROBACTERIA PHAGE T4; GENETICS; MOLECULAR MODEL; MUTATION; NUCLEAR MAGNETIC RESONANCE; PRESSURE; PROTEIN CONFORMATION; PROTON NUCLEAR MAGNETIC RESONANCE;

BACTERIOPHAGE T4; CARBON ISOTOPES; COMPUTER SIMULATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MURAMIDASE; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PRESSURE; PROTEIN CONFORMATION; PROTON MAGNETIC RESONANCE SPECTROSCOPY; RECOMBINANT PROTEINS; VIRAL PROTEINS; WATER;

EID: 84920994522     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2014.11.012     Document Type: Article

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