-
1
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-84.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
2
-
-
48549084059
-
Hepatocyte-specific Smad7 expression attenuates TGF-β-mediated fibrogenesis and protects against liver damage
-
Dooley S, Hamzavi J, Ciuclan L, et al. Hepatocyte-specific Smad7 expression attenuates TGF-β-mediated fibrogenesis and protects against liver damage. Gastroenterology 2008; 135: 642-59.
-
(2008)
Gastroenterology
, vol.135
, pp. 642-659
-
-
Dooley, S.1
Hamzavi, J.2
Ciuclan, L.3
-
3
-
-
34547599359
-
Transforming growth factor-β1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro
-
Kaimori A, Potter J, Kaimori JY, et al. Transforming growth factor-β1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro. J Biol Chem 2007; 282: 22089-101.
-
(2007)
J Biol Chem
, vol.282
, pp. 22089-22101
-
-
Kaimori, A.1
Potter, J.2
Kaimori, J.Y.3
-
4
-
-
79958050044
-
Hepatocyte-derived snail1 propagates liver fibrosis progression
-
Rowe RG, Lin Y, Shimizu-Hirota R, et al. Hepatocyte-derived snail1 propagates liver fibrosis progression. Mol Cell Biol 2011; 31: 2392-403.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2392-2403
-
-
Rowe, R.G.1
Lin, Y.2
Shimizu-Hirota, R.3
-
5
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
Zeisberg M, Yang C, Martino M, et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem 2007; 282: 23337-47.
-
(2007)
J Biol Chem
, vol.282
, pp. 23337-23347
-
-
Zeisberg, M.1
Yang, C.2
Martino, M.3
-
6
-
-
79955123951
-
Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis
-
Chu AS, Diax R, Hui JJ, et al. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. Hepatology 2011; 53: 1685-95.
-
(2011)
Hepatology
, vol.53
, pp. 1685-1695
-
-
Chu, A.S.1
Diax, R.2
Hui, J.J.3
-
7
-
-
77950597707
-
Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice
-
Taura K, Miura K, Iwaisako K, et al. Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice. Hepatology 2010; 51: 1027-36.
-
(2010)
Hepatology
, vol.51
, pp. 1027-1036
-
-
Taura, K.1
Miura, K.2
Iwaisako, K.3
-
8
-
-
84879888338
-
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
-
Yoshimoto S, Loo TM, Atarashi K, et al. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 2013; 499: 97-101.
-
(2013)
Nature
, vol.499
, pp. 97-101
-
-
Yoshimoto, S.1
Loo, T.M.2
Atarashi, K.3
-
9
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22: 894-907.
-
(2008)
Genes Dev
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
10
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert A, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.2
Paterson, E.L.3
-
11
-
-
79955954699
-
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
-
Gregory PA, Bracken CP, Smith E, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell 2011; 22: 1686-98.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1686-1698
-
-
Gregory, P.A.1
Bracken, C.P.2
Smith, E.3
-
12
-
-
84891883182
-
MicroRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition
-
in press.
-
Parikh A, Lee C, Joseph P, et al. MicroRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition. Nat Commun 2014; 5; in press.
-
(2014)
Nat Commun
, vol.5
-
-
Parikh, A.1
Lee, C.2
Joseph, P.3
-
13
-
-
84884725701
-
Polycyclic aromatic hydrocarbon (PAH)-mediated upregulation of hepatic microRNA-181 family promotes cancer cell migration by targeting MAPK phosphatase-5, regulating the activation of p38 MAPK
-
Song MK, Park YK, Ryu JC. Polycyclic aromatic hydrocarbon (PAH)-mediated upregulation of hepatic microRNA-181 family promotes cancer cell migration by targeting MAPK phosphatase-5, regulating the activation of p38 MAPK. Toxicol Appl Pharmacol 2013; 273: 130-9.
-
(2013)
Toxicol Appl Pharmacol
, vol.273
, pp. 130-139
-
-
Song, M.K.1
Park, Y.K.2
Ryu, J.C.3
-
14
-
-
84873859029
-
TGF-β upregulates miR-181a expression to promote breast cancer metastasis
-
Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP. TGF-β upregulates miR-181a expression to promote breast cancer metastasis. J Clin Investig 2013; 123: 150-63.
-
(2013)
J Clin Investig
, vol.123
, pp. 150-163
-
-
Taylor, M.A.1
Sossey-Alaoui, K.2
Thompson, C.L.3
Danielpour, D.4
Schiemann, W.P.5
-
15
-
-
77950095763
-
TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
-
Wang B, Hsu SH, Majumder S, et al. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene 2010; 29: 1787-97.
-
(2010)
Oncogene
, vol.29
, pp. 1787-1797
-
-
Wang, B.1
Hsu, S.H.2
Majumder, S.3
-
16
-
-
79953043006
-
Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
-
Wang Y, Yu Y, Tsuyada A, et al. Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene 2011; 30: 1470-80.
-
(2011)
Oncogene
, vol.30
, pp. 1470-1480
-
-
Wang, Y.1
Yu, Y.2
Tsuyada, A.3
-
17
-
-
30344473289
-
Immune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells
-
Dahlke MH, Loi R, Warren A, et al. Immune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells. J Hepatol 2006; 44: 334-41.
-
(2006)
J Hepatol
, vol.44
, pp. 334-341
-
-
Dahlke, M.H.1
Loi, R.2
Warren, A.3
-
18
-
-
84855989834
-
The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis
-
Lauer C, Brunner T, Corazza N. The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis. J Immunol 2012; 188: 916-22.
-
(2012)
J Immunol
, vol.188
, pp. 916-922
-
-
Lauer, C.1
Brunner, T.2
Corazza, N.3
-
19
-
-
53249137795
-
TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2
-
Ramesh S, Qi XJ, Wildey GM, et al. TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2. EMBO Rep 2008; 9: 990-7.
-
(2008)
EMBO Rep
, vol.9
, pp. 990-997
-
-
Ramesh, S.1
Qi, X.J.2
Wildey, G.M.3
-
20
-
-
84859445823
-
TGF-β in progression of liver disease
-
Dooley S, ten Dijke P. TGF-β in progression of liver disease. Cell Tissue Res 2012; 347: 245-56.
-
(2012)
Cell Tissue Res
, vol.347
, pp. 245-256
-
-
Dooley, S.1
ten Dijke, P.2
-
21
-
-
78650655487
-
Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim
-
Hoshino Y, Katsuno Y, Ehata S, Miyazono K. Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim. J Biochem 2011; 149: 55-65.
-
(2011)
J Biochem
, vol.149
, pp. 55-65
-
-
Hoshino, Y.1
Katsuno, Y.2
Ehata, S.3
Miyazono, K.4
-
22
-
-
70350004886
-
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics
-
Gillings AS, Balmanno K, Wiggins CM, Johnson M, Cook SJ. Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics. FEBS J 2009; 276: 6050-62.
-
(2009)
FEBS J
, vol.276
, pp. 6050-6062
-
-
Gillings, A.S.1
Balmanno, K.2
Wiggins, C.M.3
Johnson, M.4
Cook, S.J.5
-
23
-
-
33745552897
-
Dysregulation of growth factor signaling in human hepatocellular carcinoma
-
Breuhahn K, Longerich T, Schirmacher P. Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 2006; 25: 3787-800.
-
(2006)
Oncogene
, vol.25
, pp. 3787-3800
-
-
Breuhahn, K.1
Longerich, T.2
Schirmacher, P.3
-
24
-
-
79952706985
-
Transforming growth factor-beta and the hallmarks of cancer
-
Tian M, Neil JR, Schiemann WP. Transforming growth factor-beta and the hallmarks of cancer. Cell Signal 2011; 23: 951-62.
-
(2011)
Cell Signal
, vol.23
, pp. 951-962
-
-
Tian, M.1
Neil, J.R.2
Schiemann, W.P.3
-
25
-
-
34447117003
-
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
-
Gramantieri L, Ferracin M, Fornari F, et al. Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res 2007; 67: 6092-9.
-
(2007)
Cancer Res
, vol.67
, pp. 6092-6099
-
-
Gramantieri, L.1
Ferracin, M.2
Fornari, F.3
-
26
-
-
79954436127
-
MiR-21 overexpression in human primary squamous cell lung carcinoma is associated with poor patient prognosis
-
Gao W, Shen H, Liu L, et al. MiR-21 overexpression in human primary squamous cell lung carcinoma is associated with poor patient prognosis. J Cancer Res Clin Oncol 2011; 137: 557-66.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 557-566
-
-
Gao, W.1
Shen, H.2
Liu, L.3
-
27
-
-
79151484006
-
MiR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras
-
Shin KH, Bae SD, Hong HS, et al. MiR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras. Biochem Biophys Res Commun 2011; 404: 896-902.
-
(2011)
Biochem Biophys Res Commun
, vol.404
, pp. 896-902
-
-
Shin, K.H.1
Bae, S.D.2
Hong, H.S.3
-
28
-
-
77954315239
-
Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
-
Gao W, Yu Y, Cao H, et al. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed Pharmacother 2010; 64: 399-408.
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 399-408
-
-
Gao, W.1
Yu, Y.2
Cao, H.3
-
29
-
-
23044464236
-
Extensive modulation of a set of microRNAs in primary glioblastoma
-
Ciafrè SA, Galardi S, Mangiola A, et al. Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 2005; 334: 1351-8.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1351-1358
-
-
Ciafrè, S.A.1
Galardi, S.2
Mangiola, A.3
-
30
-
-
56449092072
-
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
-
Miller TE, Ghoshal K, Ramaswamy B, et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 2008; 283: 29897-903.
-
(2008)
J Biol Chem
, vol.283
, pp. 29897-29903
-
-
Miller, T.E.1
Ghoshal, K.2
Ramaswamy, B.3
-
31
-
-
68949170622
-
Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
-
Ji J, Yamashita T, Budhu A, et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 2009; 50: 472-80.
-
(2009)
Hepatology
, vol.50
, pp. 472-480
-
-
Ji, J.1
Yamashita, T.2
Budhu, A.3
-
32
-
-
60449087921
-
EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
-
Yamashita T, Ji J, Budhu A, et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 2009; 136: 1012-24.
-
(2009)
Gastroenterology
, vol.136
, pp. 1012-1024
-
-
Yamashita, T.1
Ji, J.2
Budhu, A.3
-
33
-
-
84868136612
-
MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6
-
Zhang X, Nie Y, Du Y, et al. MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. Tumor Biol 2012; 33: 1589-97.
-
(2012)
Tumor Biol
, vol.33
, pp. 1589-1597
-
-
Zhang, X.1
Nie, Y.2
Du, Y.3
-
34
-
-
84877037101
-
Activin and TGF-β regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells
-
Neel JC, Lebrun JJ. Activin and TGF-β regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells. Cell Signal 2013; 25: 1556-66.
-
(2013)
Cell Signal
, vol.25
, pp. 1556-1566
-
-
Neel, J.C.1
Lebrun, J.J.2
-
35
-
-
84868108544
-
MicroRNA-181a is associated with poor prognosis of colorectal cancer
-
Nishimura J, Handa R, Yamamoto H, et al. MicroRNA-181a is associated with poor prognosis of colorectal cancer. Oncol Rep 2012; 28: 2221-6.
-
(2012)
Oncol Rep
, vol.28
, pp. 2221-2226
-
-
Nishimura, J.1
Handa, R.2
Yamamoto, H.3
-
36
-
-
33645992763
-
Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype
-
Grimm D, Pandey K, Nakai H, Storm TA, Kay MA. Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype. J Virol 2006; 80: 426-39.
-
(2006)
J Virol
, vol.80
, pp. 426-439
-
-
Grimm, D.1
Pandey, K.2
Nakai, H.3
Storm, T.A.4
Kay, M.A.5
-
37
-
-
0032143649
-
Human hepatocyte clonal cell lines that support persistent replication of hepatitis C virus
-
Ikeda M, Sugiyama K, Mizutani T, et al. Human hepatocyte clonal cell lines that support persistent replication of hepatitis C virus. Virus Res 1998; 56: 157-67.
-
(1998)
Virus Res
, vol.56
, pp. 157-167
-
-
Ikeda, M.1
Sugiyama, K.2
Mizutani, T.3
|