Latent TGF-β1 is compartmentalized between blood and seminal plasma of HIV-positive men and its activation in semen is negatively correlated with viral load and immune activation

American Journal of Reproductive Immunology

Volumn 73, Issue 2, 2015, Pages 151-161

  Kafka, Jessica K ^a   Osborne, Brendan J W ^b   Sheth, Prameet M ^c,d   Nazli, Aisha ^a   Dizzell, Sara ^a   Huibner, Sanja ^b   Kovacs, Colin ^e   Verschoor, Chris P ^a   Bowdish, Dawn M ^a   Kaul, Rupert ^b   Kaushic, Charu ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c KINGSTON GENERAL HOSPITAL   (Canada)

^d QUEEN S UNIVERSITY   (Canada)

^e Maple Leaf Medical   (Canada)

Author keywords

Blood plasma; HIV 1; Immune activation; SCD14; Seminal plasma; TGF 1

Indexed keywords

CD14 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; LIPOPOLYSACCHARIDE;

ADULT; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PLASMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMINAL PLASMA; UPREGULATION; VIRUS LOAD; AGED; BLOOD; CELL LINE; HIV INFECTIONS; IMMUNOLOGY; MIDDLE AGED; SPERM; VIROLOGY; YOUNG ADULT;

ADULT; AGED; ANTI-HIV AGENTS; ANTIGENS, CD14; CELL LINE; HIV INFECTIONS; HUMANS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; SEMEN; TRANSFORMING GROWTH FACTOR BETA1; VIRAL LOAD; YOUNG ADULT;

EID: 84920941582     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/aji.12300     Document Type: Article

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