SirT1 knockdown potentiates radiation-induced bystander effect through promoting c-Myc activity and thus facilitating ROS accumulation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 772, Issue , 2015, Pages 23-29

  Xie, Yuexia ^a,b   Tu, Wenzhi ^a   Zhang, Jianghong ^a   He, Mingyuan ^a   Ye, Shuang ^a   Dong, Chen ^a   Shao, Chunlin ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Hepatoma and hepatocyte cells; Oxygen conditions; RIBE; ROS; SirT1 and c Myc

Indexed keywords

CATALASE; MYC PROTEIN; SIRTUIN 1; SUPEROXIDE DISMUTASE; MYC PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; SIRT1 PROTEIN, HUMAN;

ARTICLE; BIOACCUMULATION; BYSTANDER EFFECT; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IRRADIATION; LIVER CELL; MICRONUCLEUS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; RADIATION INDUCED BYSTANDER EFFECT; REPORTER GENE; SIRT1 GENE; CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; GAMMA RADIATION; GENE SILENCING; GENETICS; HEPG2 CELL LINE; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; RADIATION RESPONSE;

BYSTANDER EFFECT; CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; GAMMA RAYS; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; PROTO-ONCOGENE PROTEINS C-MYC; REACTIVE OXYGEN SPECIES; SIRTUIN 1;

EID: 84920895697     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2014.12.010     Document Type: Article

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