메뉴 건너뛰기




Volumn 214, Issue 5, 2008, Pages 610-616

Ongoing activation of p53 pathway responses is a long-term consequence of radiation exposure in vivo and associates with altered macrophage activities

Author keywords

Apoptosis; Bone marrow; Bystander effects; Immunohistochemistry; Ionizing radiation; Leukaemia; Macrophages; p53

Indexed keywords

3 NITROTYROSINE; NITROGEN; OXYGEN; PROTEIN P21; PROTEIN P53;

EID: 41649108191     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2321     Document Type: Article
Times cited : (39)

References (36)
  • 1
    • 30344448292 scopus 로고    scopus 로고
    • Ionizing radiation and leukaemia: More questions than answers
    • Wright EG. Ionizing radiation and leukaemia: more questions than answers. Hematol Oncol 2005;23:119-126.
    • (2005) Hematol Oncol , vol.23 , pp. 119-126
    • Wright, E.G.1
  • 2
    • 0242574381 scopus 로고    scopus 로고
    • Genomic instability and bystander effects induced by high-LET radiation
    • Hall EJ, Hei TK. Genomic instability and bystander effects induced by high-LET radiation. Oncogene 2003;22:7034-7042.
    • (2003) Oncogene , vol.22 , pp. 7034-7042
    • Hall, E.J.1    Hei, T.K.2
  • 3
    • 0034063909 scopus 로고    scopus 로고
    • Radiation carcinogenesis
    • Little JB. Radiation carcinogenesis. Carcinogenesis 2000;21:397-404.
    • (2000) Carcinogenesis , vol.21 , pp. 397-404
    • Little, J.B.1
  • 4
    • 0032907251 scopus 로고    scopus 로고
    • Inherited and inducible chromosomal instability: A fragile bridge between genome integrity mechanisms and tumourigenesis
    • Wright EG. Inherited and inducible chromosomal instability: a fragile bridge between genome integrity mechanisms and tumourigenesis. J Pathol 1999;187:19-27.
    • (1999) J Pathol , vol.187 , pp. 19-27
    • Wright, E.G.1
  • 5
    • 0242490151 scopus 로고    scopus 로고
    • Radiation-induced genomic instability and bystander effects: Inter-related nontargeted effects of exposure to ionizing radiation
    • Lorimore SA, Coates PJ, Wright EG. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation. Oncogene 2003;22:7058-7069.
    • (2003) Oncogene , vol.22 , pp. 7058-7069
    • Lorimore, S.A.1    Coates, P.J.2    Wright, E.G.3
  • 6
    • 33846834182 scopus 로고    scopus 로고
    • Non-targeted bystander effects induced by ionizing radiation
    • Morgan WF, Sowa MB. Non-targeted bystander effects induced by ionizing radiation. Mutat Res 2007;616:159-164.
    • (2007) Mutat Res , vol.616 , pp. 159-164
    • Morgan, W.F.1    Sowa, M.B.2
  • 8
    • 13644254917 scopus 로고    scopus 로고
    • Cell and tissue responses to genotoxic stress
    • Coates PJ, Lorimore SA, Wright EG. Cell and tissue responses to genotoxic stress. J Pathol 2005;205:221-235.
    • (2005) J Pathol , vol.205 , pp. 221-235
    • Coates, P.J.1    Lorimore, S.A.2    Wright, E.G.3
  • 9
    • 0242658543 scopus 로고    scopus 로고
    • Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation?
    • Morgan WF. Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation? Oncogene 2003;22:7094-7099.
    • (2003) Oncogene , vol.22 , pp. 7094-7099
    • Morgan, W.F.1
  • 10
    • 21344432563 scopus 로고    scopus 로고
    • Chromosomal instability in unirradiated hemopoietic cells resulting from a delayed in vivo bystander effect of gamma radiation
    • Lorimore SA, McIlrath JM, Coates PJ, Wright EG. Chromosomal instability in unirradiated hemopoietic cells resulting from a delayed in vivo bystander effect of gamma radiation. Cancer Res 2005;65:5668-5673.
    • (2005) Cancer Res , vol.65 , pp. 5668-5673
    • Lorimore, S.A.1    McIlrath, J.M.2    Coates, P.J.3    Wright, E.G.4
  • 12
    • 0034667364 scopus 로고    scopus 로고
    • Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation
    • Watson GE, Lorimore SA, Macdonald DA, Wright EG. Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation. Cancer Res 2000;60:5608-5611.
    • (2000) Cancer Res , vol.60 , pp. 5608-5611
    • Watson, G.E.1    Lorimore, S.A.2    Macdonald, D.A.3    Wright, E.G.4
  • 13
    • 0035950528 scopus 로고    scopus 로고
    • Inflammatory-type responses after exposure to ionizing radiation in vivo: A mechanism for radiation-induced bystander effects?
    • Lorimore SA, Coates PJ, Scobie GE, Milne G, Wright EG. Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects? Oncogene 2001;20:7085-7095.
    • (2001) Oncogene , vol.20 , pp. 7085-7095
    • Lorimore, S.A.1    Coates, P.J.2    Scobie, G.E.3    Milne, G.4    Wright, E.G.5
  • 14
    • 0037373853 scopus 로고    scopus 로고
    • Delayed reactivation of p53 in the progeny of cells surviving ionizing radiation
    • Suzuki K, Yokoyama S, Waseda S, Kodama S, Watanabe M. Delayed reactivation of p53 in the progeny of cells surviving ionizing radiation. Cancer Res 2003;63:936-941.
    • (2003) Cancer Res , vol.63 , pp. 936-941
    • Suzuki, K.1    Yokoyama, S.2    Waseda, S.3    Kodama, S.4    Watanabe, M.5
  • 15
    • 0033566705 scopus 로고    scopus 로고
    • Delayed apoptotic responses associated with radiation-induced neoplastic transformation of human hybrid cells
    • Mendonca MS, Howard KL, Farrington DL, Desmond LA, Temples TM, Mayhugh BM, et al. Delayed apoptotic responses associated with radiation-induced neoplastic transformation of human hybrid cells. Cancer Res 1999;59:3972-3979.
    • (1999) Cancer Res , vol.59 , pp. 3972-3979
    • Mendonca, M.S.1    Howard, K.L.2    Farrington, D.L.3    Desmond, L.A.4    Temples, T.M.5    Mayhugh, B.M.6
  • 16
    • 0028171451 scopus 로고
    • Alpha-particle-induced p53 protein expression in a rat lung epithelial cell strain
    • Hickman AW, Jaramillo RJ, Lechner JF, Johnson NF. Alpha-particle-induced p53 protein expression in a rat lung epithelial cell strain. Cancer Res 1994;54:5797-5800.
    • (1994) Cancer Res , vol.54 , pp. 5797-5800
    • Hickman, A.W.1    Jaramillo, R.J.2    Lechner, J.F.3    Johnson, N.F.4
  • 17
    • 0017904178 scopus 로고
    • Myeloid leukaemia in X-ray irradiated CBA mice
    • Major IR, Mole RH. Myeloid leukaemia in X-ray irradiated CBA mice. Nature 1978;272:455-456.
    • (1978) Nature , vol.272 , pp. 455-456
    • Major, I.R.1    Mole, R.H.2
  • 18
    • 0035075404 scopus 로고    scopus 로고
    • In vivo chromosomal instability and transmissible aberrations in the progeny of haemopoietic stem cells induced by high- and low-LET radiations
    • Watson GE, Pocock DA, Papworth D, Lorimore SA, Wright EG. In vivo chromosomal instability and transmissible aberrations in the progeny of haemopoietic stem cells induced by high- and low-LET radiations. Int J Radiat Biol 2001;77:409-417.
    • (2001) Int J Radiat Biol , vol.77 , pp. 409-417
    • Watson, G.E.1    Pocock, D.A.2    Papworth, D.3    Lorimore, S.A.4    Wright, E.G.5
  • 19
    • 4544231106 scopus 로고    scopus 로고
    • Detecting and quantifying apoptosis in tissue sections
    • Save V, Hall PA, Coates PJ. Detecting and quantifying apoptosis in tissue sections. Methods Mol Biol 2004;282:67-84.
    • (2004) Methods Mol Biol , vol.282 , pp. 67-84
    • Save, V.1    Hall, P.A.2    Coates, P.J.3
  • 20
    • 0242558968 scopus 로고    scopus 로고
    • Tissue-specific p53 responses to ionizing radiation and their genetic modification: The key to tissue-specific tumour susceptibility?
    • Coates PJ, Lorimore SA, Lindsay KJ, Wright EG. Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility? J Pathol 2003;201:377-388.
    • (2003) J Pathol , vol.201 , pp. 377-388
    • Coates, P.J.1    Lorimore, S.A.2    Lindsay, K.J.3    Wright, E.G.4
  • 21
    • 0037317216 scopus 로고    scopus 로고
    • Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors
    • Hayashi T, Kusunoki Y, Hakoda M, Morishita Y, Kubo Y, Maki M, et al. Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors. Int J Radiat Biol 2003;79:129-136.
    • (2003) Int J Radiat Biol , vol.79 , pp. 129-136
    • Hayashi, T.1    Kusunoki, Y.2    Hakoda, M.3    Morishita, Y.4    Kubo, Y.5    Maki, M.6
  • 22
  • 23
    • 27644590943 scopus 로고    scopus 로고
    • Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry
    • Nenutil R, Smardova J, Pavlova S, Hanzelkova Z, Muller P, Fabian P, et al. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry. J Pathol 2005;207:251-259.
    • (2005) J Pathol , vol.207 , pp. 251-259
    • Nenutil, R.1    Smardova, J.2    Pavlova, S.3    Hanzelkova, Z.4    Muller, P.5    Fabian, P.6
  • 24
    • 0036203197 scopus 로고    scopus 로고
    • Markers of senescence?
    • Coates PJ. Markers of senescence? J Pathol 2002;196:371- 373.
    • (2002) J Pathol , vol.196 , pp. 371-373
    • Coates, P.J.1
  • 25
    • 0035950526 scopus 로고    scopus 로고
    • Induction of endogenous beta-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice
    • Coates PJ, Lorimore SA, Rigat BA, Lane DP, Wright EG. Induction of endogenous beta-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice. Oncogene 2001;20:7096-7097.
    • (2001) Oncogene , vol.20 , pp. 7096-7097
    • Coates, P.J.1    Lorimore, S.A.2    Rigat, B.A.3    Lane, D.P.4    Wright, E.G.5
  • 27
    • 0014414665 scopus 로고
    • Influence of microbial environment on development of myeloid leukemia in X-irradiated RFM mice
    • Walburg HE Jr, Cosgrove GE, Upton AC. Influence of microbial environment on development of myeloid leukemia in X-irradiated RFM mice. Int J Cancer 1968;3:150-154.
    • (1968) Int J Cancer , vol.3 , pp. 150-154
    • Walburg Jr, H.E.1    Cosgrove, G.E.2    Upton, A.C.3
  • 28
    • 33748670457 scopus 로고    scopus 로고
    • The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
    • Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 2006;443:214-217.
    • (2006) Nature , vol.443 , pp. 214-217
    • Christophorou, M.A.1    Ringshausen, I.2    Finch, A.J.3    Swigart, L.B.4    Evan, G.I.5
  • 30
    • 0033047022 scopus 로고    scopus 로고
    • Homing and mobilization in the stem cell niche
    • Whetton AD, Graham GJ. Homing and mobilization in the stem cell niche. Trends Cell Biol 1999;9:233-238.
    • (1999) Trends Cell Biol , vol.9 , pp. 233-238
    • Whetton, A.D.1    Graham, G.J.2
  • 31
    • 28544438548 scopus 로고    scopus 로고
    • Radiation and the microenvironment - tumorigenesis and therapy
    • Barcellos-Hoff MH, Park C, Wright EG. Radiation and the microenvironment - tumorigenesis and therapy. Nature Rev Cancer 2005;5:867-875.
    • (2005) Nature Rev Cancer , vol.5 , pp. 867-875
    • Barcellos-Hoff, M.H.1    Park, C.2    Wright, E.G.3
  • 32
    • 12344318372 scopus 로고    scopus 로고
    • Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment?
    • Bissell MJ, Labarge MA. Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? Cancer Cell 2005;7:17-23.
    • (2005) Cancer Cell , vol.7 , pp. 17-23
    • Bissell, M.J.1    Labarge, M.A.2
  • 33
    • 39049141295 scopus 로고    scopus 로고
    • Indirect macrophage responses to ionizing radiation: Implications for genotype-dependent bystander signaling
    • Coates PJ, Rundle JK, Lorimore SA, Wright EG. Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling. Cancer Res 2008;68:450-456.
    • (2008) Cancer Res , vol.68 , pp. 450-456
    • Coates, P.J.1    Rundle, J.K.2    Lorimore, S.A.3    Wright, E.G.4
  • 34
    • 18144431719 scopus 로고    scopus 로고
    • Genotype-dependent induction of transmissible chromosomal instability by gamma-radiation and the benzene metabolite hydroquinone
    • Gowans ID, Lorimore SA, McIlrath JM, Wright EG. Genotype-dependent induction of transmissible chromosomal instability by gamma-radiation and the benzene metabolite hydroquinone. Cancer Res 2005;65:3527-3530.
    • (2005) Cancer Res , vol.65 , pp. 3527-3530
    • Gowans, I.D.1    Lorimore, S.A.2    McIlrath, J.M.3    Wright, E.G.4
  • 35
    • 0024440255 scopus 로고
    • Activation of bone marrow phagocytes following benzene treatment of mice
    • Laskin DL, MacEachern L, Snyder R. Activation of bone marrow phagocytes following benzene treatment of mice. Environ Health Perspect 1989;82:75-79.
    • (1989) Environ Health Perspect , vol.82 , pp. 75-79
    • Laskin, D.L.1    MacEachern, L.2    Snyder, R.3
  • 36
    • 0028960223 scopus 로고
    • Distinct actions of benzene and its metabolites on nitric oxide production by bone marrow leukocytes
    • Laskin JD, Rao NR, Punjabi CJ, Laskin DL, Synder R. Distinct actions of benzene and its metabolites on nitric oxide production by bone marrow leukocytes. J Leukoc Biol 1995;57:422-426.
    • (1995) J Leukoc Biol , vol.57 , pp. 422-426
    • Laskin, J.D.1    Rao, N.R.2    Punjabi, C.J.3    Laskin, D.L.4    Synder, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.