MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells

Circulation Research

Volumn 116, Issue 1, 2015, Pages 23-34

  Zhao, Ning ^a   Koenig, Sara N ^a   Trask, Aaron J ^a   Lin, Cho Hao ^a   Hans, Chetan P ^a   Garg, Vidu ^a   Lilly, Brenda ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

extracellular matrix; microRNAs; myocytes, smooth muscle; transforming growth factors

Indexed keywords

ANGIOTENSIN II; COLLAGEN; ELASTIN; MICRORNA 143; MICRORNA 145; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; MICRORNA; MIRN145 MICRORNA, HUMAN; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCENDING AORTA; CELL CULTURE; COCULTURE; CONTROLLED STUDY; DESCENDING AORTA; DIFFERENTIATION; DISEASE COURSE; DISEASE EXACERBATION; EXTRACELLULAR MATRIX; FIBROSIS; GENE CLUSTER; GENE CONTROL; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; MOUSE MODEL; MUSCLE DEVELOPMENT; NONHUMAN; NOTCH SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA ANALYSIS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION REGULATION; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SMOOTH MUSCLE CELL; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; CELLS, CULTURED; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 84920885784     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.303970     Document Type: Article

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