TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 89, Issue , 2015, Pages 339-346

  Shao, Yating ^a   Yang, Liang ^a   Han, Hyo Kyung ^a  

^a Dongguk University   (South Korea)

Author keywords

Anti oxidation; Bioavailability; Chitosan; Coenzyme Q10; Liposome; TPGS

Indexed keywords

CHITOSAN; CHITOSOME; LIPOSOME; REACTIVE OXYGEN METABOLITE; TOCOFERSOLAN; UBIDECARENONE; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ALPHA-TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; ANTIOXIDANT; MACROGOL DERIVATIVE; POWDER; UBIQUINONE;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; HUMAN; HUMAN CELL; MALE; MAXIMUM PLASMA CONCENTRATION; MUCOADHESION; NONHUMAN; PARTICLE SIZE; PH; PLASMA CONCENTRATION-TIME CURVE; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; BIOAVAILABILITY; CACO 2 CELL LINE; CHEMISTRY; MEDICINAL CHEMISTRY; METABOLISM; ORAL DRUG ADMINISTRATION; POWDER; PROCEDURES; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DRUG DELIVERY SYSTEMS; HUMANS; LIPOSOMES; MALE; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; UBIQUINONE; VITAMIN E;

EID: 84920864447     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.12.026     Document Type: Article

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