Rapamycin attenuates aldosterone-induced tubulointerstitial inflammation and fibrosis

Cellular Physiology and Biochemistry

Volumn 35, Issue 1, 2015, Pages 116-125

  Wang, Bin ^a   Ding, Wei ^b   Zhang, Minmin ^a   Li, Hongmei ^b   Gu, Yong ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Aldosterone; Fibrosis; Rapamycin; Tubulointerstitial Inflammation

Indexed keywords

ALDOSTERONE; ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; INTERCELLULAR ADHESION MOLECULE 1; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; RAPAMYCIN; S6 KINASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN; VIMENTIN; ANTINEOPLASTIC ANTIBIOTIC; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELLULAR SECRETION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTERSTITIAL NEPHRITIS; KIDNEY FIBROSIS; LIVER PROTECTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; FIBROSIS; GENETICS; MALE; METABOLISM; NEPHRITIS, INTERSTITIAL; PATHOLOGY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

MAMMALIA; RATTUS;

ALDOSTERONE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROSIS; HUMANS; MALE; NEPHRITIS, INTERSTITIAL; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84920834451     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000369680     Document Type: Article

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