-
1
-
-
84882571069
-
Head and neck cancer: from anatomy to biology
-
Bose P., Brockton N.T., Dort J.C. Head and neck cancer: from anatomy to biology. Int. J. Cancer 2013, 133:2013-2023. 10.1002/ijc.28112.
-
(2013)
Int. J. Cancer
, vol.133
, pp. 2013-2023
-
-
Bose, P.1
Brockton, N.T.2
Dort, J.C.3
-
2
-
-
33644778551
-
Beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury
-
Cordes N., Seidler J., Durzok R., Geinitz H., Brakebusch C. beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury. Oncogene 2006, 25:1378-1390.
-
(2006)
Oncogene
, vol.25
, pp. 1378-1390
-
-
Cordes, N.1
Seidler, J.2
Durzok, R.3
Geinitz, H.4
Brakebusch, C.5
-
3
-
-
84871967281
-
EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells
-
Eke I., Schneider L., Förster C., Zips D., Kunz-Schughart L.A., Cordes N. EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells. Cancer Res 2013, 73:297-306. 10.1158/0008-5472.CAN-12-2021.
-
(2013)
Cancer Res
, vol.73
, pp. 297-306
-
-
Eke, I.1
Schneider, L.2
Förster, C.3
Zips, D.4
Kunz-Schughart, L.A.5
Cordes, N.6
-
4
-
-
84859598676
-
Beta(1)Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy
-
Eke I., Deuse Y., Hehlgans S., Gurtner K., Krause M., Baumann M., et al. beta(1)Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy. J. Clin. Invest 2012, 122:1529-1540.
-
(2012)
J. Clin. Invest
, vol.122
, pp. 1529-1540
-
-
Eke, I.1
Deuse, Y.2
Hehlgans, S.3
Gurtner, K.4
Krause, M.5
Baumann, M.6
-
5
-
-
33748049409
-
Integrin-mediated cell-matrix interactions for prosurvival and antiapoptotic signaling after genotoxic injury
-
Cordes N. Integrin-mediated cell-matrix interactions for prosurvival and antiapoptotic signaling after genotoxic injury. Cancer Lett 2006, 242:11-19.
-
(2006)
Cancer Lett
, vol.242
, pp. 11-19
-
-
Cordes, N.1
-
6
-
-
77954353421
-
Breast cancer cells in three-dimensional culture display an enhanced radio response after coordinate targeting of integrin alpha5beta1 and fibronectin
-
Nam J.-M., Onodera Y., Bissell M.J., Park C.C. Breast cancer cells in three-dimensional culture display an enhanced radio response after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res 2010, 70:5238-5248. 10.1158/0008-5472.CAN-09-2319.
-
(2010)
Cancer Res
, vol.70
, pp. 5238-5248
-
-
Nam, J.-M.1
Onodera, Y.2
Bissell, M.J.3
Park, C.C.4
-
7
-
-
0036726312
-
Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
-
Weaver V.M., Lelièvre S., Lakins J.N., Chrenek M.A., Jones J.C.R., Giancotti F., et al. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2002, 2:205-216.
-
(2002)
Cancer Cell
, vol.2
, pp. 205-216
-
-
Weaver, V.M.1
Lelièvre, S.2
Lakins, J.N.3
Chrenek, M.A.4
Jones, J.C.R.5
Giancotti, F.6
-
8
-
-
0034893416
-
Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation
-
Damiano J.S., Hazlehurst L.A., Dalton W.S. Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation. Leukemia 2001, 15:1232-1239.
-
(2001)
Leukemia
, vol.15
, pp. 1232-1239
-
-
Damiano, J.S.1
Hazlehurst, L.A.2
Dalton, W.S.3
-
9
-
-
0037799517
-
Cell adhesion-mediated radioresistance (CAM-RR): extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro
-
Cordes N., Meineke V. Cell adhesion-mediated radioresistance (CAM-RR): extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro. Strahlenther. Onkol 2003, 179:337-344.
-
(2003)
Strahlenther. Onkol
, vol.179
, pp. 337-344
-
-
Cordes, N.1
Meineke, V.2
-
10
-
-
84907976823
-
β6 integrin induces the expression of metalloproteinase-3 and metalloproteinase-9 in colon cancer cells via ERK-ETS1 pathway
-
Gao H., Peng C., Liang B., Shahbaz M., Liu S., Wang B., et al. β6 integrin induces the expression of metalloproteinase-3 and metalloproteinase-9 in colon cancer cells via ERK-ETS1 pathway. Cancer Lett 2014, 354:427-437. 10.1016/j.canlet.2014.08.017.
-
(2014)
Cancer Lett
, vol.354
, pp. 427-437
-
-
Gao, H.1
Peng, C.2
Liang, B.3
Shahbaz, M.4
Liu, S.5
Wang, B.6
-
11
-
-
79956075585
-
Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling
-
Mantoni T.S., Lunardi S., Al-Assar O., Masamune A., Brunner T.B. Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling. Cancer Res 2011, 71:3453-3458. 10.1158/0008-5472.CAN-10-1633.
-
(2011)
Cancer Res
, vol.71
, pp. 3453-3458
-
-
Mantoni, T.S.1
Lunardi, S.2
Al-Assar, O.3
Masamune, A.4
Brunner, T.B.5
-
12
-
-
78649474761
-
Integrin signalling adaptors: not only figurants in the cancer story
-
Cabodi S., del Pilar Camacho-Leal M., Di Stefano P., Defilippi P. Integrin signalling adaptors: not only figurants in the cancer story. Nat. Rev. Cancer 2010, 10:858-870. 10.1038/nrc2967.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 858-870
-
-
Cabodi, S.1
del Pilar Camacho-Leal, M.2
Di Stefano, P.3
Defilippi, P.4
-
13
-
-
0037145037
-
Integrins: bidirectional, allosteric signaling machines in their roles as major adhesion receptors
-
Hynes R.O. Integrins: bidirectional, allosteric signaling machines in their roles as major adhesion receptors. Integrins 2002, 110:673-687.
-
(2002)
Integrins
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
14
-
-
61449213806
-
Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails
-
Legate K.R., Fässler R. Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails. J. Cell Sci 2009, 122:187-198. 10.1242/jcs.041624.
-
(2009)
J. Cell Sci
, vol.122
, pp. 187-198
-
-
Legate, K.R.1
Fässler, R.2
-
15
-
-
0033551899
-
Integrin signaling
-
Giancotti F.G. Integrin signaling. Science 1999, 285:1028-1032. 10.1126/science.285.5430.1028.
-
(1999)
Science
, vol.285
, pp. 1028-1032
-
-
Giancotti, F.G.1
-
16
-
-
33845329178
-
Signalling via integrins: implications for cell survival and anticancer strategies
-
Hehlgans S., Haase M., Cordes N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim. Biophys. Acta 2007, 1775:163-180. 10.1016/j.bbcan.2006.09.001.
-
(2007)
Biochim. Biophys. Acta
, vol.1775
, pp. 163-180
-
-
Hehlgans, S.1
Haase, M.2
Cordes, N.3
-
17
-
-
84882803879
-
Invasion as target for therapy of glioblastoma multiforme
-
Vehlow A., Cordes N. Invasion as target for therapy of glioblastoma multiforme. Biochim. Biophys. Acta - Rev, Cancer 1836, 2013:236-244.
-
(1836)
Biochim. Biophys. Acta - Rev, Cancer
, vol.2013
, pp. 236-244
-
-
Vehlow, A.1
Cordes, N.2
-
18
-
-
84883802415
-
Intracellular trafficking of integrins in cancer cells
-
Onodera Y., Nam J.-M., Sabe H. Intracellular trafficking of integrins in cancer cells. Pharmacol. Ther 2013, 140:1-9. 10.1016/j.pharmthera.2013.05.007.
-
(2013)
Pharmacol. Ther
, vol.140
, pp. 1-9
-
-
Onodera, Y.1
Nam, J.-M.2
Sabe, H.3
-
19
-
-
84899847639
-
Integrin β3 links therapy resistance and cancer stem cell properties
-
Kannan N., Nguyen L.V., Eaves C.J. Integrin β3 links therapy resistance and cancer stem cell properties. Nat. Cell Biol 2014, 16:397-399.
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 397-399
-
-
Kannan, N.1
Nguyen, L.V.2
Eaves, C.J.3
-
20
-
-
33644522372
-
New roles for integrins in squamous-cell carcinoma
-
Janes S.M., Watt F.M. New roles for integrins in squamous-cell carcinoma. Nat. Rev. Cancer 2006, 6:175-183. 10.1038/nrc1817.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 175-183
-
-
Janes, S.M.1
Watt, F.M.2
-
21
-
-
79953144790
-
Cilengitide: an RGD pentapeptide alphanubeta3 and alphanubeta5 integrin inhibitor in development for glioblastoma and other malignancies
-
Reardon D.A., Neyns B., Weller M., Tonn J.C., Nabors L.B., Stupp R. Cilengitide: an RGD pentapeptide alphanubeta3 and alphanubeta5 integrin inhibitor in development for glioblastoma and other malignancies. Future Oncol 2011, 7:339-354.
-
(2011)
Future Oncol
, vol.7
, pp. 339-354
-
-
Reardon, D.A.1
Neyns, B.2
Weller, M.3
Tonn, J.C.4
Nabors, L.B.5
Stupp, R.6
-
22
-
-
84885086130
-
Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis
-
Eke I., Storch K., Krause M., Cordes N. Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis. Cancer Res 2013, 73:5869-5879. 10.1158/0008-5472.CAN-13-0344.
-
(2013)
Cancer Res
, vol.73
, pp. 5869-5879
-
-
Eke, I.1
Storch, K.2
Krause, M.3
Cordes, N.4
-
23
-
-
84863620267
-
Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling
-
Hehlgans S., Eke I., Cordes N. Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling. Int. J. Radiat. Oncol. Biol. Phys 2012, 83:e669-e676. 10.1016/j.ijrobp.2012.01.065.
-
(2012)
Int. J. Radiat. Oncol. Biol. Phys
, vol.83
, pp. e669-e676
-
-
Hehlgans, S.1
Eke, I.2
Cordes, N.3
-
24
-
-
77952847488
-
Three-dimensional cell growth confers radioresistance by chromatin density modification
-
Storch K., Eke I., Borgmann K., Krause M., Richter C., Becker K., et al. Three-dimensional cell growth confers radioresistance by chromatin density modification. Cancer Res 2010, 70:3925-3934.
-
(2010)
Cancer Res
, vol.70
, pp. 3925-3934
-
-
Storch, K.1
Eke, I.2
Borgmann, K.3
Krause, M.4
Richter, C.5
Becker, K.6
-
25
-
-
69949162504
-
3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226
-
Hehlgans S., Lange I., Eke I., Cordes N. 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Radiother. Oncol 2009, 92:371-378. 10.1016/j.radonc.2009.08.001.
-
(2009)
Radiother. Oncol
, vol.92
, pp. 371-378
-
-
Hehlgans, S.1
Lange, I.2
Eke, I.3
Cordes, N.4
-
26
-
-
77954994889
-
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha
-
Eke I., Koch U., Hehlgans S., Sandfort V., Stanchi F., Zips D., et al. PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha. J. Clin. Invest 2010, 120:2516-2527. 10.1172/JCI41078.
-
(2010)
J. Clin. Invest
, vol.120
, pp. 2516-2527
-
-
Eke, I.1
Koch, U.2
Hehlgans, S.3
Sandfort, V.4
Stanchi, F.5
Zips, D.6
-
27
-
-
0036682924
-
Characterization of an activated mutant of focal adhesion kinase: "SuperFAK"
-
Gabarra-Niecko V., Keely P.J., Schaller M.D. Characterization of an activated mutant of focal adhesion kinase: "SuperFAK". Biochem. J. 2002, 365:591-603. 10.1042/BJ20020065.
-
(2002)
Biochem. J.
, vol.365
, pp. 591-603
-
-
Gabarra-Niecko, V.1
Keely, P.J.2
Schaller, M.D.3
-
28
-
-
33645380797
-
Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant alpha3beta1, alpha6beta1, alpha7beta1 and alpha6beta4 integrins
-
Nishiuchi R., Takagi J., Hayashi M., Ido H., Yagi Y., Sanzen N., et al. Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant alpha3beta1, alpha6beta1, alpha7beta1 and alpha6beta4 integrins. Matrix Biol 2006, 25:189-197. 10.1016/j.matbio.2005.12.001.
-
(2006)
Matrix Biol
, vol.25
, pp. 189-197
-
-
Nishiuchi, R.1
Takagi, J.2
Hayashi, M.3
Ido, H.4
Yagi, Y.5
Sanzen, N.6
-
29
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674. 10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
30
-
-
36849053853
-
Beta1 integrin as a molecular therapeutic target
-
Cordes N., Park C.C. beta1 integrin as a molecular therapeutic target. Int. J. Radiat. Biol 2007, 83:753-760. 10.1080/09553000701639694.
-
(2007)
Int. J. Radiat. Biol
, vol.83
, pp. 753-760
-
-
Cordes, N.1
Park, C.C.2
-
31
-
-
84865732679
-
Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by beta1 integrin inhibition
-
Eke I., Dickreuter E., Cordes N. Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by beta1 integrin inhibition. Radiother. Oncol 2012, 104:235-242. 10.1016/j.radonc.2012.05.009.
-
(2012)
Radiother. Oncol
, vol.104
, pp. 235-242
-
-
Eke, I.1
Dickreuter, E.2
Cordes, N.3
-
32
-
-
0027933266
-
Transformation and tumor progression are frequently associated with expression of the alpha 3/beta 1 heterodimer in solid tumors
-
Bartolazzi A., Cerboni C., Nicotra M.R., Mottolese M., Bigotti A., Natali P.G. Transformation and tumor progression are frequently associated with expression of the alpha 3/beta 1 heterodimer in solid tumors. Int. J. Cancer 1994, 58:488-491.
-
(1994)
Int. J. Cancer
, vol.58
, pp. 488-491
-
-
Bartolazzi, A.1
Cerboni, C.2
Nicotra, M.R.3
Mottolese, M.4
Bigotti, A.5
Natali, P.G.6
-
33
-
-
84893053467
-
Integrin alpha3beta1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma
-
Zhou B., Gibson-Corley K.N., Herndon M.E., Sun Y., Gustafson-Wagner E., Teoh-Fitzgerald M., et al. Integrin alpha3beta1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma. Mol. Cancer Res 2014, 12:143-154. 10.1158/1541-7786.mcr-13-0184.
-
(2014)
Mol. Cancer Res
, vol.12
, pp. 143-154
-
-
Zhou, B.1
Gibson-Corley, K.N.2
Herndon, M.E.3
Sun, Y.4
Gustafson-Wagner, E.5
Teoh-Fitzgerald, M.6
-
34
-
-
41149156919
-
Diagnostic value of integrin alpha3, beta4, and beta5 gene expression levels for the clinical outcome of tongue squamous cell carcinoma
-
Kurokawa A., Nagata M., Kitamura N., Noman A., Ohnishi M., Ohyama T., et al. Diagnostic value of integrin alpha3, beta4, and beta5 gene expression levels for the clinical outcome of tongue squamous cell carcinoma. Cancer 2008, 112:1272-1281. 10.1002/cncr.23295.
-
(2008)
Cancer
, vol.112
, pp. 1272-1281
-
-
Kurokawa, A.1
Nagata, M.2
Kitamura, N.3
Noman, A.4
Ohnishi, M.5
Ohyama, T.6
-
35
-
-
84883611645
-
ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma
-
Nagata M., Noman A., Suzuki K., Kurita H., Ohnishi M., Ohyama T., et al. ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma. BMC Cancer 2013, 13:410. 10.1186/1471-2407-13-410.
-
(2013)
BMC Cancer
, vol.13
, pp. 410
-
-
Nagata, M.1
Noman, A.2
Suzuki, K.3
Kurita, H.4
Ohnishi, M.5
Ohyama, T.6
-
36
-
-
84883464903
-
Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes
-
Shirakihara T., Kawasaki T., Fukagawa A., Semba K., Sakai R., Miyazono K., et al. Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes. Cancer Sci 2013, 104:1189-1197. 10.1111/cas.12220.
-
(2013)
Cancer Sci
, vol.104
, pp. 1189-1197
-
-
Shirakihara, T.1
Kawasaki, T.2
Fukagawa, A.3
Semba, K.4
Sakai, R.5
Miyazono, K.6
-
37
-
-
33646253672
-
Akt signaling and cancer: surviving but not moving on
-
Toker A., Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res 2006, 66:3963-3966. 10.1158/0008-5472.CAN-06-0743.
-
(2006)
Cancer Res
, vol.66
, pp. 3963-3966
-
-
Toker, A.1
Yoeli-Lerner, M.2
-
38
-
-
67649448820
-
Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer
-
Van Slambrouck S., Jenkins A.R., Romero A.E., Steelant W.F. Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer. Int. J. Oncol 2009, 34:1717-1726. 10.3892/ijo.
-
(2009)
Int. J. Oncol
, vol.34
, pp. 1717-1726
-
-
Van Slambrouck, S.1
Jenkins, A.R.2
Romero, A.E.3
Steelant, W.F.4
-
39
-
-
84906934465
-
Signaling events mediated by alpha3beta1 integrin are essential for mammary tumorigenesis
-
Cagnet S., Faraldo M.M., Kreft M., Sonnenberg A., Raymond K., Glukhova M.A. Signaling events mediated by alpha3beta1 integrin are essential for mammary tumorigenesis. Oncogene 2014, 33:4286-4295. 10.1038/onc.2013.391.
-
(2014)
Oncogene
, vol.33
, pp. 4286-4295
-
-
Cagnet, S.1
Faraldo, M.M.2
Kreft, M.3
Sonnenberg, A.4
Raymond, K.5
Glukhova, M.A.6
|