Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

Chemico-Biological Interactions

Volumn 227, Issue , 2015, Pages 63-68

  Stuchlíková, Lucie ^a   Matoušková, Petra ^a   Bártíková, Hana ^a   Vokřál, Ivan ^a   Lamka, Jiří ^a   Štolcová, Tereza ^a   Pětníková, Hana ^a   Szotáková, Barbora ^a   Kubíček, Vladimír ^a   Skálová, Lenka ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Anthelmintics; CYP3A; CYP3A24; Drugdrug interactions; Zolvix

Indexed keywords

7 METHOXY 4 TRIFLUOROMETHYLCOUMARIN; ALKYLOXYRESORUFIN DERIVATIVE; COUMARIN DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 3A24; DEXAMETHASONE; ISOENZYME; LIVER ENZYME; MESSENGER RNA; MIDAZOLAM; MONEPANTEL; RESORUFIN DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG; AMINOACETONITRILE; CYTOCHROME P450 3A; ISOPROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME MODIFICATION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LIVER CELL; LIVER HOMOGENATE; LIVER MICROSOME; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RECOMMENDED DRUG DOSE; SHEEP; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; LIVER; METABOLISM;

ANIMALIA; OVIS; OVIS ARIES;

AMINOACETONITRILE; ANIMALS; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; HEPATOCYTES; LIVER; PROTEIN ISOFORMS; RNA, MESSENGER; SHEEP;

EID: 84920735898     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.12.025     Document Type: Article

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