메뉴 건너뛰기




Volumn 20, Issue 30, 2014, Pages 10296-10304

Prognostic relevance of minimal residual disease in colorectal cancer

Author keywords

Circulating tumor cells; Colorectal cancer; Disseminated tumor cells; Isolated tumor cells; Micrometastases; Minimal residual disease; Occult disease

Indexed keywords

ARTICLE; BONE MARROW METASTASIS; CANCER DIAGNOSIS; CANCER EPIDEMIOLOGY; CANCER GROWTH; CANCER PATIENT; CANCER PROGNOSIS; CANCER RESEARCH; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CELL FUNCTION; CIRCULATING TUMOR CELL; COLORECTAL CANCER; DISEASE ASSOCIATION; DISTANT METASTASIS; HIGH RISK PATIENT; HUMAN; IN VITRO STUDY; IN VIVO STUDY; ISOLATED TUMOR CELL; LYMPH NODE CELL; LYMPH NODE METASTASIS; MICROMETASTASIS; MINIMAL RESIDUAL DISEASE; MOUSE MODEL; NONHUMAN; OCCULT CANCER; TRANSLATIONAL RESEARCH; TUMOR CELL; ANIMAL; BONE MARROW; COLORECTAL NEOPLASMS; LYMPH NODE; MORTALITY; PATHOLOGY; PERSONALIZED MEDICINE; PREDICTIVE VALUE; RISK ASSESSMENT; RISK FACTOR; TREATMENT OUTCOME; TUMOR EMBOLISM; TUMOR RECURRENCE;

EID: 84920608327     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i30.10296     Document Type: Article
Times cited : (32)

References (67)
  • 1
    • 84872967522 scopus 로고    scopus 로고
    • Cancer statistics, 2013
    • PMID: 23335087
    • Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013; 63: 11-30 [PMID: 23335087 DOI: 10.3322/caac.21166]
    • (2013) CA Cancer J Clin , vol.63 , pp. 11-30
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 5
    • 0000110505 scopus 로고
    • A case of cancer in which cells similar to those in the tumours were seen in the blood after death
    • Ashworth T. A case of cancer in which cells similar to those in the tumours were seen in the blood after death. Aus Med J 1869; 14: 146-9
    • (1869) Aus Med J , vol.14 , pp. 146-149
    • Ashworth, T.1
  • 6
    • 84863892963 scopus 로고    scopus 로고
    • Biology and significance of circulating and disseminated tumour cells in colorectal cancer
    • PMID: 22350614
    • Steinert G, Schölch S, Koch M, Weitz J. Biology and significance of circulating and disseminated tumour cells in colorectal cancer. Langenbecks Arch Surg 2012; 397: 535-542 [PMID: 22350614 DOI: 10.1007/s00423-012-0917-9]
    • (2012) Langenbecks Arch Surg , vol.397 , pp. 535-542
    • Steinert, G.1    Schölch, S.2    Koch, M.3    Weitz, J.4
  • 7
    • 0034687663 scopus 로고    scopus 로고
    • Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood
    • PMID: 11121063
    • Chang YS, di Tomaso E, McDonald DM, Jones R, Jain RK, Munn LL. Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci USA 2000; 97: 14608-14613 [PMID: 11121063 DOI: 10.1073/pnas.97.26.14608]
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 14608-14613
    • Chang, Y.S.1    Di Tomaso, E.2    McDonald, D.M.3    Jones, R.4    Jain, R.K.5    Munn, L.L.6
  • 8
    • 0014865396 scopus 로고
    • Metastasis: Guantitative analysis of distribution and fate of tumor embolilabeled with 125 I-5-iodo-2'-deoxyuridine
    • PMID: 5513503
    • Fidler IJ. Metastasis: guantitative analysis of distribution and fate of tumor embolilabeled with 125 I-5-iodo-2'-deoxyuridine. J Natl Cancer Inst 1970; 45: 773-782 [PMID: 5513503]
    • (1970) J Natl Cancer Inst , vol.45 , pp. 773-782
    • Fidler, I.J.1
  • 9
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • PMID: 16493418
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7: 131-142 [PMID: 16493418 DOI: 10.1038/nrm1835]
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 10
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • PMID: 19945376
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell 2009; 139: 871-890 [PMID: 19945376 DOI: 10.1016/j.cell.2009.11.007]
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 11
    • 0030452985 scopus 로고    scopus 로고
    • Mesenchyme to epithelium transition during development of the mammalian kidney tubule
    • PMID: 9124036
    • Davies JA. Mesenchyme to epithelium transition during development of the mammalian kidney tubule. Acta Anat (Basel) 1996; 156: 187-201 [PMID: 9124036]
    • (1996) Acta Anat (Basel) , vol.156 , pp. 187-201
    • Davies, J.A.1
  • 12
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • PMID: 17332325
    • Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res 2007; 67: 1979-1987 [PMID: 17332325 DOI: 10.1158/0008-5472.CAN-06-1479]
    • (2007) Cancer Res , vol.67 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.H.6
  • 14
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • PMID: 16098727
    • Huber MA, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 2005; 17: 548-558 [PMID: 16098727 DOI: 10.1016/j.ceb.2005.08.001]
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 16
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • PMID: 10647931
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70 [PMID: 10647931]
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 17
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • PMID: 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674 [PMID: 21376230 DOI: 10.1016/j.cell.2011.02.013]
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 19
    • 2942538264 scopus 로고    scopus 로고
    • Dissecting the metastatic cascade
    • PMID: 15170447
    • Pantel K, Brakenhoff RH. Dissecting the metastatic cascade. Nat Rev Cancer 2004; 4: 448-456 [PMID: 15170447 DOI: 10.1038/nrc1370]
    • (2004) Nat Rev Cancer , vol.4 , pp. 448-456
    • Pantel, K.1    Brakenhoff, R.H.2
  • 20
    • 41949093229 scopus 로고    scopus 로고
    • Influence of two different resection techniques (conventional liver resection versus anterior approach) of liver metastases from colorectal cancer on hematogenous tumor cell dissemination -prospective randomized multicenter trial
    • PMID: 18321372
    • Schmidt T, Koch M, Antolovic D, Reissfelder C, Schmitz-Winnenthal FH, Rahbari NN, Schmidt J, Seiler CM, Büchler MW, Weitz J. Influence of two different resection techniques (conventional liver resection versus anterior approach) of liver metastases from colorectal cancer on hematogenous tumor cell dissemination -prospective randomized multicenter trial. BMC Surg 2008; 8: 6 [PMID: 18321372 DOI: 10.1186/1471-2482-8-6]
    • (2008) BMC Surg , vol.8 , pp. 6
    • Schmidt, T.1    Koch, M.2    Antolovic, D.3    Reissfelder, C.4    Schmitz-Winnenthal, F.H.5    Rahbari, N.N.6    Schmidt, J.7    Seiler, C.M.8    Büchler, M.W.9    Weitz, J.10
  • 22
    • 33847383651 scopus 로고    scopus 로고
    • Increased detection rate and potential prognostic impact of disseminated tumor cells in patients undergoing endorectal ultrasound for rectal cancer
    • PMID: 16758164
    • Koch M, Antolovic D, Kienle P, Horstmann J, Herfarth C, von Knebel Doeberitz M, Weitz J. Increased detection rate and potential prognostic impact of disseminated tumor cells in patients undergoing endorectal ultrasound for rectal cancer. Int J Colorectal Dis 2007; 22: 359-365 [PMID: 16758164 DOI: 10.1007/s00384-006-0152-3]
    • (2007) Int J Colorectal Dis , vol.22 , pp. 359-365
    • Koch, M.1    Antolovic, D.2    Kienle, P.3    Horstmann, J.4    Herfarth, C.5    Von Knebel Doeberitz, M.6    Weitz, J.7
  • 23
    • 79952770095 scopus 로고    scopus 로고
    • Circulating tumour cells: Their utility in cancer management and predicting outcomes
    • PMID: 21789147
    • Krebs MG, Hou JM, Ward TH, Blackhall FH, Dive C. Circulating tumour cells: their utility in cancer management and predicting outcomes. Ther Adv Med Oncol 2010; 2: 351-365 [PMID: 21789147 DOI: 10.1177/1758834010378414]
    • (2010) Ther Adv Med Oncol , vol.2 , pp. 351-365
    • Krebs, M.G.1    Hou, J.M.2    Ward, T.H.3    Blackhall, F.H.4    Dive, C.5
  • 24
    • 51649120140 scopus 로고    scopus 로고
    • Review: Biological relevance of disseminated tumor cells in cancer patients
    • PMID: 18712708
    • Riethdorf S, Wikman H, Pantel K. Review: Biological relevance of disseminated tumor cells in cancer patients. Int J Cancer 2008; 123: 1991-2006 [PMID: 18712708 DOI: 10.1002/ijc.23825]
    • (2008) Int J Cancer , vol.123 , pp. 1991-2006
    • Riethdorf, S.1    Wikman, H.2    Pantel, K.3
  • 28
    • 84855528629 scopus 로고    scopus 로고
    • Molecular detection of tumor cells in regional lymph nodes is associated with disease recur-rence and poor survival in node-negative colorectal cancer: A systematic review and meta-analysis
    • PMID: 22124103
    • Rahbari NN, Bork U, Motschall E, Thorlund K, Büchler MW, Koch M, Weitz J. Molecular detection of tumor cells in regional lymph nodes is associated with disease recur-rence and poor survival in node-negative colorectal cancer: a systematic review and meta-analysis. J Clin Oncol 2012; 30: 60-70 [PMID: 22124103 DOI: 10.1200/JCO.2011.36.9504]
    • (2012) J Clin Oncol , vol.30 , pp. 60-70
    • Rahbari, N.N.1    Bork, U.2    Motschall, E.3    Thorlund, K.4    Büchler, M.W.5    Koch, M.6    Weitz, J.7
  • 31
    • 6044259206 scopus 로고    scopus 로고
    • Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases
    • PMID: 15501967
    • Allard WJ, Matera J, Miller MC, Repollet M, Connelly MC, Rao C, Tibbe AG, Uhr JW, Terstappen LW. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clin Cancer Res 2004; 10: 6897-6904 [PMID: 15501967 DOI: 10.1158/1078-0432.CCR-04-0378]
    • (2004) Clin Cancer Res , vol.10 , pp. 6897-6904
    • Allard, W.J.1    Matera, J.2    Miller, M.C.3    Repollet, M.4    Connelly, M.C.5    Rao, C.6    Tibbe, A.G.7    Uhr, J.W.8    Terstappen, L.W.9
  • 33
    • 84885843652 scopus 로고    scopus 로고
    • Essentials of circulating tumor cells for clinical research and practice
    • PMID: 23830807
    • Liberko M, Kolostova K, Bobek V. Essentials of circulating tumor cells for clinical research and practice. Crit Rev Oncol Hematol 2013; 88: 338-356 [PMID: 23830807 DOI: 10.1016/j.critrevonc.2013.05.002]
    • (2013) Crit Rev Oncol Hematol , vol.88 , pp. 338-356
    • Liberko, M.1    Kolostova, K.2    Bobek, V.3
  • 34
    • 0035148564 scopus 로고    scopus 로고
    • Comparative analysis of tumor cell dissemination in mesenteric, central, and peripheral venous blood in patients with colorectal cancer
    • PMID: 11146784
    • Koch M, Weitz J, Kienle P, Benner A, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M. Comparative analysis of tumor cell dissemination in mesenteric, central, and peripheral venous blood in patients with colorectal cancer. Arch Surg 2001; 136: 85-89 [PMID: 11146784]
    • (2001) Arch Surg , vol.136 , pp. 85-89
    • Koch, M.1    Weitz, J.2    Kienle, P.3    Benner, A.4    Willeke, F.5    Lehnert, T.6    Herfarth, C.7    Von Knebel Doeberitz, M.8
  • 35
    • 84868287226 scopus 로고    scopus 로고
    • Detection methods of circulating tumor cells
    • PMID: 23050102
    • Pantel K, Alix-Panabières C. Detection methods of circulating tumor cells. J Thorac Dis 2012; 4: 446-447 [PMID: 23050102 DOI: 10.3978/j.issn.2072-1439.2012.08.15]
    • (2012) J Thorac Dis , vol.4 , pp. 446-447
    • Pantel, K.1    Alix-Panabières, C.2
  • 36
    • 84863587972 scopus 로고    scopus 로고
    • Ultrasensitive clinical enumeration of rare cells ex vivo using a micro-hall detector
    • PMID: 22764208
    • Issadore D, Chung J, Shao H, Liong M, Ghazani AA, Castro CM, Weissleder R, Lee H. Ultrasensitive clinical enumeration of rare cells ex vivo using a micro-hall detector. Sci Transl Med 2012; 4: 141ra92 [PMID: 22764208 DOI: 10.1126/scitranslmed.3003747]
    • (2012) Sci Transl Med , vol.4 , pp. 141ra92
    • Issadore, D.1    Chung, J.2    Shao, H.3    Liong, M.4    Ghazani, A.A.5    Castro, C.M.6    Weissleder, R.7    Lee, H.8
  • 40
  • 41
    • 79955030814 scopus 로고    scopus 로고
    • Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer
    • PMID: 21422427
    • Iinuma H, Watanabe T, Mimori K, Adachi M, Hayashi N, Tamura J, Matsuda K, Fukushima R, Okinaga K, Sasako M, Mori M. Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. J Clin Oncol 2011; 29: 1547-1555 [PMID: 21422427 DOI: 10.1200/JCO.2010.30.5151]
    • (2011) J Clin Oncol , vol.29 , pp. 1547-1555
    • Iinuma, H.1    Watanabe, T.2    Mimori, K.3    Adachi, M.4    Hayashi, N.5    Tamura, J.6    Matsuda, K.7    Fukushima, R.8    Okinaga, K.9    Sasako, M.10    Mori, M.11
  • 43
    • 77951585096 scopus 로고    scopus 로고
    • Heterogeneous detection of circulating tumor cells in patients with colorectal cancer by immunomagnetic enrichment using different EpCAM-specific antibodies
    • PMID: 20426872
    • Antolovic D, Galindo L, Carstens A, Rahbari N, Büchler MW, Weitz J, Koch M. Heterogeneous detection of circulating tumor cells in patients with colorectal cancer by immunomagnetic enrichment using different EpCAM-specific antibodies. BMC Biotechnol 2010; 10: 35 [PMID: 20426872 DOI: 10.1186/1472-6750-10-35]
    • (2010) BMC Biotechnol , vol.10 , pp. 35
    • Antolovic, D.1    Galindo, L.2    Carstens, A.3    Rahbari, N.4    Büchler, M.W.5    Weitz, J.6    Koch, M.7
  • 44
    • 12744273125 scopus 로고    scopus 로고
    • Detection of hematogenous tumor cell dissemination predicts tumor relapse in patients undergoing surgical resection of colorectal liver metastases
    • PMID: 15650626
    • Koch M, Kienle P, Hinz U, Antolovic D, Schmidt J, Herfarth C, von Knebel Doeberitz M, Weitz J. Detection of hematogenous tumor cell dissemination predicts tumor relapse in patients undergoing surgical resection of colorectal liver metastases. Ann Surg 2005; 241: 199-205 [PMID: 15650626]
    • (2005) Ann Surg , vol.241 , pp. 199-205
    • Koch, M.1    Kienle, P.2    Hinz, U.3    Antolovic, D.4    Schmidt, J.5    Herfarth, C.6    Von Knebel Doeberitz, M.7    Weitz, J.8
  • 45
    • 84920572080 scopus 로고    scopus 로고
    • Health C for D and R. Recently-Approved Device-Cell-SearchTM Epithelial Cell Kit /CellSpotterTM Analyzer -K031588 [Internet]. [cited 2013 Oct 23]
    • Health C for D and R. Recently-Approved Device-Cell-SearchTM Epithelial Cell Kit /CellSpotterTM Analyzer -K031588 [Internet]. [cited 2013 Oct 23]. Available from: URL: http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/DeviceApprovalsandClearances/Recently-ApprovedDevices/ucm081239.htm
  • 47
    • 0035447983 scopus 로고    scopus 로고
    • Detection of tumor cells in the portal and peripheral blood of patients with colorectal carcinoma using competitive reverse transcriptase-polymerase chain reaction
    • PMID: 11571740
    • Sadahiro S, Suzuki T, Tokunaga N, Yurimoto S, Yasuda S, Tajima T, Makuuchi H, Murayama C, Matsuda K. Detection of tumor cells in the portal and peripheral blood of patients with colorectal carcinoma using competitive reverse transcriptase-polymerase chain reaction. Cancer 2001; 92: 1251-1258 [PMID: 11571740]
    • (2001) Cancer , vol.92 , pp. 1251-1258
    • Sadahiro, S.1    Suzuki, T.2    Tokunaga, N.3    Yurimoto, S.4    Yasuda, S.5    Tajima, T.6    Makuuchi, H.7    Murayama, C.8    Matsuda, K.9
  • 48
    • 0030424139 scopus 로고    scopus 로고
    • Study of the arterial pattern of the rectum and its clinical application
    • PMID: 9096745
    • Shafik A, Mostafa H. Study of the arterial pattern of the rectum and its clinical application. Acta Anat (Basel) 1996; 157: 80-86 [PMID: 9096745]
    • (1996) Acta Anat (Basel) , vol.157 , pp. 80-86
    • Shafik, A.1    Mostafa, H.2
  • 50
    • 0026806148 scopus 로고
    • Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients
    • PMID: 1381801
    • Lindemann F, Schlimok G, Dirschedl P, Witte J, Riethmüller G. Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients. Lancet 1992; 340: 685-689 [PMID: 1381801]
    • (1992) Lancet , vol.340 , pp. 685-689
    • Lindemann, F.1    Schlimok, G.2    Dirschedl, P.3    Witte, J.4    Riethmüller, G.5
  • 51
    • 52049116094 scopus 로고    scopus 로고
    • Cancer micrometastasis and tumour dormancy
    • PMID: 18834417
    • Wikman H, Vessella R, Pantel K. Cancer micrometastasis and tumour dormancy. APMIS 2008; 116: 754-770 [PMID: 18834417 DOI: 10.1111/j.1600-0463.2008.01033.x]
    • (2008) APMIS , vol.116 , pp. 754-770
    • Wikman, H.1    Vessella, R.2    Pantel, K.3
  • 52
    • 84865004049 scopus 로고    scopus 로고
    • Disseminated tumor cells in the bone marrow negatively influence survival after resection of colorectal liver metastases
    • PMID: 22395998
    • Hinz S, Bockhorst J, Röder C, Egberts JH, Schafmayer C, Küchler T, Becker T, Kalthoff H. Disseminated tumor cells in the bone marrow negatively influence survival after resection of colorectal liver metastases. Ann Surg Oncol 2012; 19: 2539-2546 [PMID: 22395998 DOI: 10.1245/s10434-012-2291-9]
    • (2012) Ann Surg Oncol , vol.19 , pp. 2539-2546
    • Hinz, S.1    Bockhorst, J.2    Röder, C.3    Egberts, J.H.4    Schafmayer, C.5    Küchler, T.6    Becker, T.7    Kalthoff, H.8
  • 53
    • 0028010876 scopus 로고
    • Identification of occult micrometastases in pericolic lymph nodes of Duke's B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival
    • PMID: 7507795
    • Greenson JK, Isenhart CE, Rice R, Mojzisik C, Houchens D, Martin EW. Identification of occult micrometastases in pericolic lymph nodes of Duke's B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival. Cancer 1994; 73: 563-569 [PMID: 7507795]
    • (1994) Cancer , vol.73 , pp. 563-569
    • Greenson, J.K.1    Isenhart, C.E.2    Rice, R.3    Mojzisik, C.4    Houchens, D.5    Martin, E.W.6
  • 54
    • 0037083251 scopus 로고    scopus 로고
    • Prognostic significance of cytokeratin-20 reverse transcriptase polymerase chain reaction in lymph nodes of node-negative colorectal cancer patients
    • PMID: 11844829
    • Rosenberg R, Hoos A, Mueller J, Baier P, Stricker D, Werner M, Nekarda H, Siewert JR. Prognostic significance of cytokeratin-20 reverse transcriptase polymerase chain reaction in lymph nodes of node-negative colorectal cancer patients. J Clin Oncol 2002; 20: 1049-1055 [PMID: 11844829]
    • (2002) J Clin Oncol , vol.20 , pp. 1049-1055
    • Rosenberg, R.1    Hoos, A.2    Mueller, J.3    Baier, P.4    Stricker, D.5    Werner, M.6    Nekarda, H.7    Siewert, J.R.8
  • 55
    • 0028230541 scopus 로고
    • The prognostic significance of immunohistochemically detected lymph node micrometastases in colorectal carcinoma
    • PMID: 7513353
    • Jeffers MD, O'Dowd GM, Mulcahy H, Stagg M, O'Donoghue DP, Toner M. The prognostic significance of immunohistochemically detected lymph node micrometastases in colorectal carcinoma. J Pathol 1994; 172: 183-187 [PMID: 7513353 DOI: 10.1002/path.1711720205]
    • (1994) J Pathol , vol.172 , pp. 183-187
    • Jeffers, M.D.1    O'dowd, G.M.2    Mulcahy, H.3    Stagg, M.4    O'donoghue, D.P.5    Toner, M.6
  • 56
    • 84872048462 scopus 로고    scopus 로고
    • Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer
    • PMID: 23136247
    • Gasch C, Bauernhofer T, Pichler M, Langer-Freitag S, Reeh M, Seifert AM, Mauermann O, Izbicki JR, Pantel K, Riethdorf S. Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer. Clin Chem 2013; 59: 252-260 [PMID: 23136247 DOI: 10.1373/clinchem.2012.188557]
    • (2013) Clin Chem , vol.59 , pp. 252-260
    • Gasch, C.1    Bauernhofer, T.2    Pichler, M.3    Langer-Freitag, S.4    Reeh, M.5    Seifert, A.M.6    Mauermann, O.7    Izbicki, J.R.8    Pantel, K.9    Riethdorf, S.10
  • 58
    • 0016696542 scopus 로고
    • Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure
    • PMID: 1149045
    • Corbett TH, Griswold DP, Roberts BJ, Peckham JC, Schabel FM. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 1975; 35: 2434-2439 [PMID: 1149045]
    • (1975) Cancer Res , vol.35 , pp. 2434-2439
    • Corbett, T.H.1    Griswold, D.P.2    Roberts, B.J.3    Peckham, J.C.4    Schabel, F.M.5
  • 59
    • 0015715862 scopus 로고
    • Evaluation of dimethylhydrazine induced tumours in mice as a model system for colorectal cancer
    • PMID: 4131500
    • Haase P, Cowen DM, Knowles JC, Cooper EH. Evaluation of dimethylhydrazine induced tumours in mice as a model system for colorectal cancer. Br J Cancer 1973; 28: 530-543 [PMID: 4131500]
    • (1973) Br J Cancer , vol.28 , pp. 530-543
    • Haase, P.1    Cowen, D.M.2    Knowles, J.C.3    Cooper, E.H.4
  • 60
    • 0017700371 scopus 로고
    • Colonic neoplasms in mice produced with six injections of 1, 2-dimethylhydrazine
    • PMID: 593654
    • Deschner EE, Long FC. Colonic neoplasms in mice produced with six injections of 1, 2-dimethylhydrazine. Oncology 1977; 34: 255-257 [PMID: 593654]
    • (1977) Oncology , vol.34 , pp. 255-257
    • Deschner, E.E.1    Long, F.C.2
  • 62
    • 0023114809 scopus 로고
    • An animal model for colon cancer metastasis: Establishment and characterization of murine cell lines with enhanced liver-metastasizing ability
    • PMID: 3028609
    • Bresalier RS, Hujanen ES, Raper SE, Roll FJ, Itzkowitz SH, Martin GR, Kim YS. An animal model for colon cancer metastasis: establishment and characterization of murine cell lines with enhanced liver-metastasizing ability. Cancer Res 1987; 47: 1398-1406 [PMID: 3028609]
    • (1987) Cancer Res , vol.47 , pp. 1398-1406
    • Bresalier, R.S.1    Hujanen, E.S.2    Raper, S.E.3    Roll, F.J.4    Itzkowitz, S.H.5    Martin, G.R.6    Kim, Y.S.7
  • 63
    • 0025942251 scopus 로고
    • Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens
    • PMID: 1924398
    • Fu XY, Besterman JM, Monosov A, Hoffman RM. Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. Proc Natl Acad Sci USA 1991; 88: 9345-9349 [PMID: 1924398]
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9345-9349
    • Fu, X.Y.1    Besterman, J.M.2    Monosov, A.3    Hoffman, R.M.4
  • 65
    • 2942574538 scopus 로고    scopus 로고
    • Fodstad Ø. Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
    • PMID: 15196545
    • Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H, Fodstad Ø. Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur J Cancer 2004; 40: 1593-1598 [PMID: 15196545 DOI: 10.1016/j.ejca.2004.02.023]
    • (2004) Eur J Cancer , vol.40 , pp. 1593-1598
    • Flatmark, K.1    Maelandsmo, G.M.2    Martinsen, M.3    Rasmussen, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.