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Volumn 18, Issue 6, 2012, Pages 799-806

Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis

Author keywords

Epidemiology; Epstein Barr virus; human herpesvirus 6; multiple sclerosis

Indexed keywords

EPSTEIN BARR VIRUS ANTIBODY; HUMAN HERPESVIRUS 6 ANTIBODY; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

EID: 84861795775     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458511428081     Document Type: Review
Times cited : (44)

References (37)
  • 2
    • 80051535245 scopus 로고    scopus 로고
    • Current and past Epstein-Barr virus infection in risk of initial CNS demyelination
    • Lucas RM, Ponsonby AL, Dear K, et al. Current and past Epstein-Barr virus infection in risk of initial CNS demyelination. Neurology. 2011 ; 77: 371-379
    • (2011) Neurology , vol.77 , pp. 371-379
    • Lucas, R.M.1    Ponsonby, A.L.2    Dear, K.3
  • 3
    • 0036321307 scopus 로고    scopus 로고
    • Human herpes virus 6 and multiple sclerosis
    • Moore FG, Wolfson C. Human herpes virus 6 and multiple sclerosis. Acta Neurol Scand. 2002 ; 106: 63-83
    • (2002) Acta Neurol Scand , vol.106 , pp. 63-83
    • Moore, F.G.1    Wolfson, C.2
  • 4
    • 35548960964 scopus 로고    scopus 로고
    • Human herpesviruses in MS
    • Christensen T. Human herpesviruses in MS. Int MS J. 2007 ; 14: 41-47
    • (2007) Int MS J , vol.14 , pp. 41-47
    • Christensen, T.1
  • 5
    • 0037309220 scopus 로고    scopus 로고
    • Cross-reactivity with myelin basic protein and human herpesvirus-6 in multiple sclerosis
    • Tejada-Simon MV, Zang YC, Hong J, Rivera VM, Zhang JZ. Cross-reactivity with myelin basic protein and human herpesvirus-6 in multiple sclerosis. Ann Neurol. 2003 ; 53: 189-197
    • (2003) Ann Neurol , vol.53 , pp. 189-197
    • Tejada-Simon, M.V.1    Zang, Y.C.2    Hong, J.3    Rivera, V.M.4    Zhang, J.Z.5
  • 6
    • 49249116710 scopus 로고    scopus 로고
    • EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-{gamma} and IL-2
    • Lunemann JD, Jelcic I, Roberts S, et al. EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-{gamma} and IL-2. J Exp Med. 2008 ; 205: 1763-1773
    • (2008) J Exp Med , vol.205 , pp. 1763-1773
    • Lunemann, J.D.1    Jelcic, I.2    Roberts, S.3
  • 7
    • 0036779194 scopus 로고    scopus 로고
    • Human herpesvirus 6 and multiple sclerosis: A study of T cell cross-reactivity to viral and myelin basic protein antigens
    • Cirone M, Cuomo L, Zompetta C, et al. Human herpesvirus 6 and multiple sclerosis: a study of T cell cross-reactivity to viral and myelin basic protein antigens. J Med Virol. 2002 ; 68: 268-272
    • (2002) J Med Virol , vol.68 , pp. 268-272
    • Cirone, M.1    Cuomo, L.2    Zompetta, C.3
  • 8
    • 0033868149 scopus 로고    scopus 로고
    • Association between clinical disease activity and Epstein-Barr virus reactivation in MS
    • Wandinger K, Jabs W, Siekhaus A, et al. Association between clinical disease activity and Epstein-Barr virus reactivation in MS. Neurology. 2000 ; 55: 178-184
    • (2000) Neurology , vol.55 , pp. 178-184
    • Wandinger, K.1    Jabs, W.2    Siekhaus, A.3
  • 10
    • 0036307787 scopus 로고    scopus 로고
    • Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression
    • Berti R, Brennan MB, Soldan SS, et al. Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. J Neurovirol. 2002 ; 8: 250-256
    • (2002) J Neurovirol , vol.8 , pp. 250-256
    • Berti, R.1    Brennan, M.B.2    Soldan, S.S.3
  • 11
    • 4644303317 scopus 로고    scopus 로고
    • Beta-interferon treatment reduces human herpesvirus-6 viral load in multiple sclerosis relapses but not in remission
    • Alvarez-Lafuente R, De Las Heras V, Bartolome M, Picazo JJ, Arroyo R. Beta-interferon treatment reduces human herpesvirus-6 viral load in multiple sclerosis relapses but not in remission. Eur Neurol. 2004 ; 52: 87-91
    • (2004) Eur Neurol , vol.52 , pp. 87-91
    • Alvarez-Lafuente, R.1    De Las Heras, V.2    Bartolome, M.3    Picazo, J.J.4    Arroyo, R.5
  • 12
    • 28144448320 scopus 로고    scopus 로고
    • Presence of Epstein-Barr virus and human herpesvirus 6B DNA in multiple sclerosis patients: Associations with disease activity
    • Höllsberg P, Kusk M, Bech E, Hansen HJ, Jakobsen J, Haahr S. Presence of Epstein-Barr virus and human herpesvirus 6B DNA in multiple sclerosis patients: associations with disease activity. Acta Neurol Scand. 2005 ; 112: 395-402
    • (2005) Acta Neurol Scand , vol.112 , pp. 395-402
    • Höllsberg, P.1    Kusk, M.2    Bech, E.3    Hansen, H.J.4    Jakobsen, J.5    Haahr, S.6
  • 14
    • 79960320278 scopus 로고    scopus 로고
    • Human herpesvirus 6 and effectiveness of interferon beta 1b in multiple sclerosis patients
    • Garcia-Montojo M, De Las Heras V, Dominguez-Mozo M, et al. Human herpesvirus 6 and effectiveness of interferon beta 1b in multiple sclerosis patients. Eur J Neurol. 2011 ; 18: 1027-1035
    • (2011) Eur J Neurol , vol.18 , pp. 1027-1035
    • Garcia-Montojo, M.1    De Las Heras, V.2    Dominguez-Mozo, M.3
  • 15
    • 0032943438 scopus 로고    scopus 로고
    • Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis
    • Goldberg SH, Albright AV, Lisak RP, Gonzalez-Scarano F. Polymerase chain reaction analysis of human herpesvirus-6 sequences in the sera and cerebrospinal fluid of patients with multiple sclerosis. J Neurovirol. 1999 ; 5: 134-139
    • (1999) J Neurovirol , vol.5 , pp. 134-139
    • Goldberg, S.H.1    Albright, A.V.2    Lisak, R.P.3    Gonzalez-Scarano, F.4
  • 16
    • 79959568900 scopus 로고    scopus 로고
    • Human herpesvirus-6 viral load and antibody titer in serum samples of patients with multiple sclerosis
    • Behzad-Behbahani A, Mikaeili MH, Entezam M, et al. Human herpesvirus-6 viral load and antibody titer in serum samples of patients with multiple sclerosis. J Microbiol Immunol Infect. 2011 ; 44: 247-251
    • (2011) J Microbiol Immunol Infect , vol.44 , pp. 247-251
    • Behzad-Behbahani, A.1    Mikaeili, M.H.2    Entezam, M.3
  • 17
    • 68249150707 scopus 로고    scopus 로고
    • Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI
    • Farrell RA, Antony D, Wall GR, et al. Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology. 2009 ; 73: 32-38
    • (2009) Neurology , vol.73 , pp. 32-38
    • Farrell, R.A.1    Antony, D.2    Wall, G.R.3
  • 18
    • 77955020345 scopus 로고    scopus 로고
    • Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis
    • Castellazzi M, Tamborino C, Cani A, et al. Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis. Mult Scler. 2010 ; 16: 883-887
    • (2010) Mult Scler , vol.16 , pp. 883-887
    • Castellazzi, M.1    Tamborino, C.2    Cani, A.3
  • 19
    • 78650455250 scopus 로고    scopus 로고
    • Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity
    • Ingram G, Bugert JJ, Loveless S, Robertson NP. Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity. Eur J Neurol. 2010 ; 17: 1386-1389
    • (2010) Eur J Neurol , vol.17 , pp. 1386-1389
    • Ingram, G.1    Bugert, J.J.2    Loveless, S.3    Robertson, N.P.4
  • 20
    • 0038038037 scopus 로고    scopus 로고
    • The immune response against herpesvirus is more prominent in the early stages of MS
    • Villoslada P, Juste C, Tintore M, et al. The immune response against herpesvirus is more prominent in the early stages of MS. Neurology. 2003 ; 60: 1944-1948
    • (2003) Neurology , vol.60 , pp. 1944-1948
    • Villoslada, P.1    Juste, C.2    Tintore, M.3
  • 21
    • 17444453701 scopus 로고    scopus 로고
    • Association of human herpes virus 6 (HHV-6) with multiple sclerosis: Increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA
    • Soldan SS, Berti R, Salem N, et al. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nat Med. 1997 ; 3: 1394-1397
    • (1997) Nat Med , vol.3 , pp. 1394-1397
    • Soldan, S.S.1    Berti, R.2    Salem, N.3
  • 22
    • 67349263039 scopus 로고    scopus 로고
    • Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis
    • Pittas F, Ponsonby AL, van der Mei IA, et al. Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis. J Neurol. 2009 ; 256: 577-585
    • (2009) J Neurol , vol.256 , pp. 577-585
    • Pittas, F.1    Ponsonby, A.L.2    Van Der Mei, I.A.3
  • 23
    • 77955291052 scopus 로고    scopus 로고
    • Higher 25-hydroxyvitamin D is associated with lower relapse risk in MS
    • Simpson SL, Taylor B, Blizzard L, et al. Higher 25-hydroxyvitamin D is associated with lower relapse risk in MS. Ann Neurol. 2010 ; 68: 193-203
    • (2010) Ann Neurol , vol.68 , pp. 193-203
    • Simpson, S.L.1    Taylor, B.2    Blizzard, L.3
  • 24
    • 4344658431 scopus 로고    scopus 로고
    • Distribution and quantification of human herpesvirus 6 in multiple sclerosis and control brains
    • Tuke PW, Hawke S, Griffiths PD, Clark DA. Distribution and quantification of human herpesvirus 6 in multiple sclerosis and control brains. Mult Scler. 2004 ; 10: 355-359
    • (2004) Mult Scler , vol.10 , pp. 355-359
    • Tuke, P.W.1    Hawke, S.2    Griffiths, P.D.3    Clark, D.A.4
  • 25
    • 0029142819 scopus 로고
    • Plaque-associated expression of human herpesvirus 6 in multiple sclerosis
    • Challoner PB, Smith KT, Parker JD, et al. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci U S A. 1995 ; 92: 7440-7444
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7440-7444
    • Challoner, P.B.1    Smith, K.T.2    Parker, J.D.3
  • 26
    • 27144501566 scopus 로고    scopus 로고
    • Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes
    • Ahlqvist J, Fotheringham J, Akhyani N, Yao K, Fogdell-Hahn A, Jacobson S. Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. J Neurovirol. 2005 ; 11: 384-394
    • (2005) J Neurovirol , vol.11 , pp. 384-394
    • Ahlqvist, J.1    Fotheringham, J.2    Akhyani, N.3    Yao, K.4    Fogdell-Hahn, A.5    Jacobson, S.6
  • 27
    • 22544434363 scopus 로고    scopus 로고
    • Variant-specific tropism of human herpesvirus 6 in human astrocytes
    • Donati D, Martinelli E, Cassiani-Ingoni R, et al. Variant-specific tropism of human herpesvirus 6 in human astrocytes. J Virol. 2005 ; 79: 9439-9448
    • (2005) J Virol , vol.79 , pp. 9439-9448
    • Donati, D.1    Martinelli, E.2    Cassiani-Ingoni, R.3
  • 28
    • 43449125605 scopus 로고    scopus 로고
    • Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes
    • Fotheringham J, Williams EL, Akhyani N, Jacobson S. Human herpesvirus 6 (HHV-6) induces dysregulation of glutamate uptake and transporter expression in astrocytes. J Neuroimmune Pharmacol. 2008 ; 3: 105-116
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 105-116
    • Fotheringham, J.1    Williams, E.L.2    Akhyani, N.3    Jacobson, S.4
  • 29
    • 77955982744 scopus 로고    scopus 로고
    • Mechanism of neuroinflammation: Enhanced cytotoxicity and IL-17 production via CD46 binding
    • Yao K, Graham J, Akahata Y, Oh U, Jacobson S. Mechanism of neuroinflammation: enhanced cytotoxicity and IL-17 production via CD46 binding. J Neuroimmune Pharmacol. 2010 ; 5: 469-478
    • (2010) J Neuroimmune Pharmacol , vol.5 , pp. 469-478
    • Yao, K.1    Graham, J.2    Akahata, Y.3    Oh, U.4    Jacobson, S.5
  • 31
    • 18744409058 scopus 로고    scopus 로고
    • Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses
    • Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses. Rev Med Virol. 2005 ; 15: 179-211
    • (2005) Rev Med Virol , vol.15 , pp. 179-211
    • Christensen, T.1
  • 32
    • 0344450781 scopus 로고    scopus 로고
    • Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family
    • Blond JL, Beseme F, Duret L, et al. Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family. J Virol. 1999 ; 73: 1175-1185
    • (1999) J Virol , vol.73 , pp. 1175-1185
    • Blond, J.L.1    Beseme, F.2    Duret, L.3
  • 33
    • 70349976491 scopus 로고    scopus 로고
    • Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis
    • Perron H, Bernard C, Bertrand JB, et al. Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis. J Neurol Sci. 2009 ; 286: 65-72
    • (2009) J Neurol Sci , vol.286 , pp. 65-72
    • Perron, H.1    Bernard, C.2    Bertrand, J.B.3
  • 34
    • 20144387928 scopus 로고    scopus 로고
    • Human endogenous retrovirus (HERV)-W ENV and GAG proteins: Physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions
    • Perron H, Lazarini F, Ruprecht K, et al. Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions. J Neurovirol. 2005 ; 11: 23-33
    • (2005) J Neurovirol , vol.11 , pp. 23-33
    • Perron, H.1    Lazarini, F.2    Ruprecht, K.3
  • 35
    • 23944526944 scopus 로고    scopus 로고
    • Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response
    • Derfuss T, Hohlfeld R, Meinl E. Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response. J Neurol. 2005 ; 252: 968-971
    • (2005) J Neurol , vol.252 , pp. 968-971
    • Derfuss, T.1    Hohlfeld, R.2    Meinl, E.3
  • 37
    • 0030964403 scopus 로고    scopus 로고
    • Human herpesvirus-6 reactivation in a longitudinal study of two HIV-1 infected patients
    • Iuliano R, Trovato R, Lico S, et al. Human herpesvirus-6 reactivation in a longitudinal study of two HIV-1 infected patients. J Med Virol. 1997 ; 51: 259-264
    • (1997) J Med Virol , vol.51 , pp. 259-264
    • Iuliano, R.1    Trovato, R.2    Lico, S.3


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